Vol 7 korvaa täysin Vol 6:n. Linkit, joiden täydentäminen alkoi 7.2.2021. esitetään uusimmat ylimpänä. Tämä nopeuttaa kiinnostavimpien, usein uusimpien linkkien löytämistä. Jatkuvasti päivittyvät löytyvät edelleen alimpana.
Disclaimer: Tästä ja edellisistä viidestä linkkikokoelmasta löytyvät artikkelit eivät muodosta täydellistä, edustavaa, suositeltua eikä luotettavaksi varmennettua koostetta eri medioissa julkaistuista SARS-CoV-2 virukseen, Covid-19 sairauteen, sen hoitoon tai estämiseen liittyvistä artikkeleista.
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Six-month sequelae of post-vaccination SARS-CoV-2 infection: A retrospective cohort study of 10,024 breakthrough infections. Brain Behaviour Immunity. NN.7.2022. https://www.sciencedirect.com/science/article/pii/S0889159122001118
July 11-20
July 1-10
Long-COVID in children and adolescents: a systematic review and meta-analyses. Scientific Reports, 23.6.2022. https://www.nature.com/articles/s41598-022-13495-5
Long COVID symptoms in SARS-CoV-2-positive children aged 0–14 years and matched controls in Denmark (LongCOVIDKidsDK): a national, cross-sectional study. Lancet. 22.6.2022. https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(22)00154-7/fulltext
June 21-30
Outcomes of SARS-CoV-2 Reinfection [US Veterans study, 0…1…2…3 infections]. Research Square. 17.6.2022. https://www.researchsquare.com/article/rs-1749502/v1
Persistent circulating SARS-CoV-2 spike is associated with post-acute COVID-19 sequelae. medRxiv.16.6.2022. https://www.medrxiv.org/content/10.1101/2022.06.14.22276401v1
Life expectancy in racial and ethnic groups in the USA. Lancet. 16.6.2022. The Lancet | The best science for better lives
Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure. Science 14.6.2022. https://www.science.org/doi/10.1126/science.abq1841
People who caught Covid in first wave get ‘no immune boost’ from Omicron
Study of triple vaccinated people also says Omicron infection does little to reduce chance of catching variant again. Guardian. 14.6.2022. https://www.theguardian.com/world/2022/jun/14/people-who-caught-covid-in-first-wave-get-no-immune-boost-from-omicron?CMP=Share_iOSApp_Other
Japan Has Fewest Covid-19 Deaths Per Capita in OECD, New Data Show
Widespread mask-wearing and relatively little obesity in East Asia are cited for low mortality rate, but lessons remain elusive. WSJ. 13.6.2022. https://www.wsj.com/articles/japan-has-fewest-covid-19-deaths-per-capita-in-oecd-new-data-show-11655116829
Relax, This Isn’t the Future of Japanese Tourism. It’s easy to be frustrated with Japan’s slow reopening, but the country needs to learn to let down its guard first. Bloomberg. 13.6.2022. https://www.bloomberg.com/opinion/articles/2022-06-12/relax-tourism-to-japan-is-not-becoming-like-north-korea#xj4y7vzkg
Yle: Husin johtajaylilääkäri varoittaa kesän koronakuolemista – ”Kehitys voi olla varsin huolestuttava”. Markku Mäkijärvi pitää kesäkuukausia tartuntojen kannalta riskialttiina, koska ihmiset liikkuvat ja lomailevat paljon. Ilta=Sanomat. 13.6.2022. https://www.is.fi/kotimaa/art-2000008881999.html
June 11-20
Neurodevelopmental Outcomes at 1 Year in Infants of Mothers Who Tested Positive for SARS-CoV-2 During Pregnancy. JAMA. 9.6.2022. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2793178
Study Finds Previous Covid-19 Infection Doesn’t Protect Children From Omicron. Forbes. 9.6.2022. https://www.forbes.com/sites/williamhaseltine/2022/06/09/study-finds-previous-covid-19-infection-doesnt-protect-children-from-omicron/?sh=49cf6e9e1176
Hallitus laatii pelisääntöjä syksyn korona-aallon varalle – Koronapassilla ei enää voisi kiertää rajoituksia, jos niihin turvaudutaan. Hallitus kerää lausuntoja tartuntatautilakiin ehdotetuista muutoksista. Mediuutiset 8.6.2022. https://www.mediuutiset.fi/uutiset/mu/9f7492b9-942f-4298-b4e8-3ea828ea8161
Nirmatrelvir Resistant SARS-CoV-2 Variants with High Fitness in Vitro. bioRxiv. 7.6.2022. https://www.biorxiv.org/content/10.1101/2022.06.06.494921v1
The substitutions L50F, E166A and L167F in SARS-CoV-2 3CLpro are selected by a protease inhibitor in vitro and confer resistance to nirmatrelvir. bioRxiv. 7.6.2022. https://www.biorxiv.org/content/10.1101/2022.06.07.495116v1
U.S. CDC removes mask recommendation from monkeypox travel notice to avoid confusion. Reuters. 7.6.2022. https://www.reuters.com/world/us/us-cdc-removes-mask-recommendation-monkeypox-travel-notice-avoid-confusion-2022-06-07/
Suomessa on varastossa yli 3 miljoonaa koronarokotetta – ylilääkäri kommentoi. Suomen suuret koronarokotevarastot ovat monen tekijän summa. Iltalehti. 6.6.2022. https://www.iltalehti.fi/terveysuutiset/a/1a472435-f0dd-4758-8cbf-a1aef16b9cc0
What Our COVID-19 Response Can Teach Us About Dealing With Monkeypox. TIME. 6.6.2022. https://view.newsletters.time.com/?qs=9cb58f3b3de900675050d37e9b6ffb7f1046c9a1ae9705166182eecc6f650ee06006c91f5ac2b1d08814c8613a974a32c9e21a0b23c631e31989e7d00123d09625d8bc616f83a350777fe2b0696e294c&fbclid=IwAR3-zUmfPNK1KYaybI8s8IhOaAfQRaxLWEvhiiJNJCZOBTphHED9CZ0Hb9k
Short-term Mortality Fluctuations. HMD Short-Term Human Mortality Database. 6.6.2022. https://mpidr.shinyapps.io/stmortality/
How Swedish authorities worked to export “herd immunity” to other countries. The following is a submission to the Global Workers’ Inquest into the COVID-19 Pandemic from anti-COVID activists Keith Begg and Virpi Flyg on the efforts of the Swedish government to export its “herd immunity” strategy of mass infection to countries throughout the world. Begg is a communications specialist from Ireland who holds both Irish and Swedish citizenship, and the founder of Media Watchdogs of Sweden. Flyg is a writer, translator, and social media influencer from Finland. World Socioalist Web Site. 5.6.2022. https://www.wsws.org/en/articles/2022/06/06/swed-j06.html
Suomalaistutkijat alkavat etsiä kiivaasti long covidin alatyyppejä – diagnoosien määrä on jopa nelinkertaistunut lyhyessä ajassa
Helsingin yliopistollisen sairaalan johtaman tutkimushankkeen tavoitteena on selvittää koronavirusinfektion jälkeisten pitkäaikaisten oireiden eli long covidin taustalla olevia mekanismeja.YLE Uutiset. 4.6.2022. https://yle.fi/uutiset/3-12468334
Can long Covid lead to death? A new analysis suggests it could
The CDC is beginning to look at death certificates that indicate more than 100 people who died had long Covid. Politico. 3.6.2022. https://www.politico.com/news/2022/06/03/can-long-covid-lead-to-death-a-new-analysis-suggests-it-could-00036845
Omicron subvariant drives spike in cases and deaths in Portugal
Europe faces prospect of further Covid measures later in the year as share of Omicron BA.5 cases rise in Portugal and Germany. Guardian. 3.6.2022. https://www.theguardian.com/world/2022/jun/03/omicron-covid-subvariant-drives-spike-in-cases-and-deaths-in-portgual?CMP=Share_iOSApp_Other
Lasse Lehtoselta kritiikkiä THL:n rokotussuosituksista: ”Hifistelyä” – näkee myös asiakastyytyväisyyden vaarantuvan. Helsingin ja Uudenmaan sairaanhoitopiirin diagnostiikkajohtaja ja terveysoikeuden professori Lasse Lehtonen antaa kritiikkiä THL:n tänään päivittämästä rokotussuosituksesta. Demokraatti. 2.6.2022. https://demokraatti.fi/lasse-lehtoselta-kritiikkia-thln-rokotussuosituksista-hifistelya-nakee-myos-asiakastyytyvaisyyden-vaarantuvan
Yli 80-vuotiaiden ylikuolleisuudella ei selvää yhteyttä tehosterokotusten myöhäiseen aloitukseen. FaktaBaari. 2.6.2022. https://www.faktabaari.fi/fakta/yli-80-vuotiaiden-ylikuolleisuudella-ei-selvaa-yhteytta-tehosterokotusten-myohaiseen-aloitukseen/
Why did Covid disappear from our collective consciousness so quickly?
Brigid Delaney. Guardian. 2.6.2022. https://www.theguardian.com/commentisfree/2022/jun/03/why-did-covid-disappear-from-our-collective-consciousness-so-quickly
Efficacy and Safety of a Recombinant Plant-Based Adjuvanted Covid-19 Vaccine. NEJM. 2.6.2022. https://www.nejm.org/doi/full/10.1056/NEJMoa2201300
Why does viral RNA sometimes persist after recovery from acute infections? PLOS Biology. 1.6.2022. https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3001687
COVID death tolls: scientists acknowledge errors in WHO estimates
Researchers with the World Health Organization explain mistakes in high-profile mortality estimates for Germany and Sweden.. nature. 1.6.2022. https://www.nature.com/articles/d41586-022-01526-0?utm_source=Nature+Briefing&utm_campaign=1436525283-briefing-dy-20220601&utm_medium=email&utm_term=0_c9dfd39373-1436525283-46822866
Hyvästi, Koronavilkku! Sovellus lopetti toimintansa – Sen kautta tehtiin 64 000 tartuntailmoitusta. Mediuutiset. 1.6.2022. https://www.mediuutiset.fi/uutiset/mu/f72367c1-f0c0-41c1-b36d-82457a0bdf7b?ref=newsletter:e718&utm_source=uutiskirje%40mediuutiset.fi&utm_medium=email&utm_campaign=MU-Uutiskirje-laakari
June 1-10
During the Omicron Wave, Death Rates Soared for Older People
Last year, people 65 and older died from Covid at lower rates than in previous waves. But with Omicron and waning immunity, death rates rose again. New York Times. 31.5.2022. https://www.nytimes.com/2022/05/31/health/omicron-deaths-age-65-elderly.html
Mask wearing in community settings reduces SARS-CoV-2 transmission. PNAS. 31.5.2022. https://www.pnas.org/doi/10.1073/pnas.2119266119
Living with covid cannot save lives, but research can. BMJ. 30.5.2022. https://www.bmj.com/content/377/bmj.o1361
Monitoring for SARS-CoV-2 drug resistance mutations in broad viral populations. bioRxiv. 30.5.2022. https://www.biorxiv.org/content/10.1101/2022.05.27.493798v1
COVID-19: Infektionen hinterlassen bei Kindern keinen Antikörperschutz vor Omikron. 30.5.2022. https://www.aerzteblatt.de/nachrichten/134653/COVID-19-Infektionen-hinterlassen-bei-Kindern-keinen-Antikoerperschutz-vor-Omikron?utm_source=dlvr.it&utm_medium=twitter
Secretoglobin family 1D member 2 (SCGB1D2) protein inhibits growth of Borrelia burgdorferi and affects susceptibility to Lyme disease. bioRxiv. 28.5.2022. https://www.biorxiv.org/content/10.1101/2022.05.27.493784v1
On the Trail of Long COVID. TIME. 26.5.2022. https://view.newsletters.time.com/?qs=7655bc242c5b342e5fb155e57cad97209b4badce519bcf744c4012e3ac96471e53f513725b0c4e0158e7cea04ca0ad76012970bcb2e05b541e8b6b0551b0dc6822cf87e979b88be24d3847588b973482&fbclid=IwAR0C8kVgWIbRoWIjs3dNxUWWu4yIvjbAElOvNVeAdAuYjIheN40UFKBGKrE
Long COVID after breakthrough SARS-CoV-2 infection. Nature Medicine.25.5.2022. https://www.nature.com/articles/s41591-022-01840-0
Kuolleisuus on kasvanut, mutta THL ei tingi neljänsien koronarokotteiden ikärajasta – ”En uskonut silmiäni”, sanoo Maijaliisa Aho, 72
Moni ikäihminen odottaa muutoksia rokotusten ikärajoihin. Asiantuntijat ovat erimielisiä, eikä Kansallisen rokotusasiantuntijaryhmän päätöskään ollut yksimielinen.YLE Uutiset. 25.5.2022. https://yle.fi/uutiset/3-12461806
Suomen ensimmäinen apinarokkotartunta hyvin todennäköinen. HUSissa on todettu aikuisella miespotilaalla orthopox-ryhmään kuuluvan viruksen aiheuttama tartunta. Apina- ja isorokkovirukset ovat orthopoxviruksia. Lopullinen varmistus apinarokkotartunnasta saadaan, kun näytteen sekvensointi valmistuu loppuviikolla. STT Info (HUS). 25.5.2022. https://www.sttinfo.fi/tiedote/suomen-ensimmainen-apinarokkotartunta-hyvin-todennakoinen?publisherId=23980819&releaseId=69942501
Why the Air at the Gym May Be More Likely to Spread Covid. A new study found exercisers expel a shocking number of tiny aerosol particles when they are working hard. New York Times. 24.5.2022. https://www.nytimes.com/2022/05/24/well/move/covid-gym-air.html
Post-COVID C+onditions Among Adult COVID-19 Survivors Aged 18-64 and >65 Years – United States, March 2020-November 2021. CDC MMWR. 24.5.2022. https://www.cdc.gov/mmwr/volumes/71/wr/mm7121e1.htm
Aerosol particle emission increases exponentially above moderate exercise intensity resulting in superemission during maximal exercise. 23.5.2022. PNAS. https://www.pnas.org/doi/10.1073/pnas.2202521119
As Monkeypox Cases Rise, Nations Are Urged to Examine Vaccine Stores
The United States has stockpiled millions of doses of two smallpox vaccines, also effective against monkeypox. But the outbreaks so far are clustered in other countries. New York Times. 23.5.2022. https://www.nytimes.com/2022/05/23/health/monkeypox-vaccines.html?referringSource=articleShare
COVID-19 symptoms and duration of direct antigen test positivity at a community testing and surveillance site, January 2021-2022. medRxiv. 23.5.2022. https://www.medrxiv.org/content/10.1101/2022.05.19.22274968v1
How Rapid Reinfection Has Changed the Covid Fight. New variants can infect people who had Covid-19 as recently as a few months ago. The Mew Republic. 23.5.2022. https://newrepublic.com/article/166573/reinfection-ba2-omicron-covid
Widening of inequalities in COVID- 19 years of life lost from 2020 to 2021: a Scottish Burden of Disease Study. JECH. 21.5.2022.https://jech.bmj.com/content/jech/early/2022/05/24/jech-2022-219090.full.pdf
May 21-31
Excess Mortality in Massachusetts During the Delta and Omicron Waves of COVID-19. JAMA. 20.5.2022. https://jamanetwork.com/journals/jama/fullarticle/2792738?
Child hepatitis cases up to almost 200, say public health officials. ‘It’s important that parents know the likelihood of their child developing hepatitis is extremely low’ says UKHSA. Independent. 20.5.2022. https://www.independent.co.uk/news/health/child-hepatitis-public-health-b2083855.html
Monkeypox in Australia: what is it and how can we prevent the spread? The Conversation. 20.5.2022. https://theconversation.com/monkeypox-in-australia-what-is-it-and-how-can-we-prevent-the-spread-183526
So, Have You Heard About Monkeypox? A new viral outbreak is testing whether the world has learned anything from COVID. Atlantic. 20.5.2022. https://www.theatlantic.com/health/archive/2022/05/monkeypox-outbreak-covid-pandemic/629920/
SARSCoV2 variants of concern and variants under investigation in England Technical briefing 42. UK Health Security Agency. 20.5.2022. extension://elhekieabhbkpmcefcoobjddigjcaadp/https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1077180/Technical-Briefing-42-20May2022.pdf
Want to prevent pandemics? Stop spillovers. Decision-makers discussing landmark agreements on health and biodiversity must include four actions to reduce the risk of animals and people exchanging viruses. Nature. 19.5.2022. https://media.nature.com/original/magazine-assets/d41586-022-01312-y/d41586-022-01312-y.pdf
Ensimmäinen poliotapaus 30 vuoteen on vahvistettu Mosambikissa – Virus hävitettiin Afrikasta jo kertaalleen. Maailman terveysjärjestön (WHO) Afrikan-aluejohtaja Matshidiso Moeti totesi uuden löydöksen olevan ”erittäin huolestuttava”. Helsingin Sanomat. 19.5.2022. https://www.hs.fi/ulkomaat/art-2000008830045.html
Korona aiheuttaa edelleen runsaasti poissaoloja työpaikoilta – korvaushakemuksia on niin paljon jonossa, että Kela palkkaa 50 uutta käsittelijää. S-ryhmässä alkuvuosi oli haastava omikronin viedessä työntekijöitä sairauslomille. Pandemian aikana koronapoissaolot ovat pakottaneet jopa sulkemaan yksittäisiä S-ryhmän liikkeitä tai lyhentämään aukioloa. YLE Uutiset. 19.5.2022. https://yle.fi/uutiset/3-12450525
Apinarokko on isorokon varjo. (Aivelo) Tiede. 19.5.2022. https://www.tiede.fi/blogit/kaiken-takana-loinen/apinarokko-isorokon-varjo
Neutralization Escape by the SARS-CoV-2 Omicron Variants BA.2.12.1 and BA.4/BA.5 medRxiv. 19.5.2022. https://www.medrxiv.org/content/10.1101/2022.05.16.22275151v1
Erkenntnisse zu Covid-Infektionen: Warum manche Menschen kein Corona hatten. Während der Omikron-Welle haben sich Millionen Menschen mit Sars-CoV-2 infiziert. Manche hatten aber bisher noch nie ein positives Testergebnis. Woran kann das liegen? BaZ Wissen. 18.5.2022. https://www.bazonline.ch/warum-manche-menschen-kein-corona-hatten-318416937600?
The pandemic’s true health cost: how much of our lives has COVID stolen? Researchers are trying to calculate how many years have been lost to disability and death. (DALY) Nature. 18.5.2022. https://www.nature.com/articles/d41586-022-01341-7?
Monkeypox – United Kingdom of Great Britain and Northern Ireland. WHO. 18.5.2022. https://www.who.int/emergencies/disease-outbreak-news/item/2022-DON383
U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak. STAT. 18.5.2022. https://www.statnews.com/2022/05/18/spain-portugal-report-monkeypox-cases-raising-specter-of-wider-outbreak/?
Onko kesä peruttu? Tehoavatko rokotteet? Viisi kysymystä ja vastausta Suomeen rantautuneesta uudesta omikronvariantista
Turun yliopistollinen keskussairaala kertoi keskiviikkona löytäneensä potilaalta Suomen ensimmäisen Etelä-Afrikan omikronvariantin. YLE Uutiset. 18.5.2022. https://yle.fi/uutiset/3-12451831
Limited cross-variant immunity from SARS-CoV-2 Omicron without vaccination. nature.18.5.2022. https://www.nature.com/articles/s41586-022-04865-0.
Omicron Infection Induces Low-Level, Narrow-Range SARS-CoV-2 Neutralizing Activity. Lancet. 16.5.2022. https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4099400
Coronavirus may be linked to cases of severe hepatitis in children. Reuters. 16.5.2022. https://www.reuters.com/business/healthcare-pharmaceuticals/coronavirus-may-be-linked-cases-severe-hepatitis-children-2022-05-16/
The Answer to Stopping the Coronavirus May Be Up Your Nose. New York Times. 16.5.2022. https://www.nytimes.com/2022/05/16/opinion/covid-nasal-vaccine.html
Just how accurate are rapid antigen tests? Two testing experts explain the latest data. The Conversation. 16.5.2022. https://theconversation.com/just-how-accurate-are-rapid-antigen-tests-two-testing-experts-explain-the-latest-data-180405?
Avohilmo: Perusterveydenhuollon avohoidon ICD-10 – käyntisyyt. THL jatkuvasti päivittyvä? https://sampo.thl.fi/pivot/prod/fi/avo/perus06/summary_icd1001?alue_0=11810&alue_1=&alue_2=&palvelumuoto_0=33780&ammattiryhm%C3%A4_0=30664&ik%C3%A4luokat_0=109987&sukupuoli_0=11936&mittari_0=100050&drill-diagnoosi=11
How Australia Saved Thousands of Lives While Covid Killed a Million Americans. The United States and Australia share similar demographics, but their pandemic death rates point to very different cultures of trust. New York Times. 15.5.2022. https://www.nytimes.com/2022/05/15/world/australia/covid-deaths.html?referringSource=articleShare
Multivariate profile and acute-phase correlates of cognitive deficits in a COVID-19 hospitalised cohort. eClinicalMedicine. NN.5.2022. https://www.sciencedirect.com/science/article/pii/S258953702200147X
Post COVID-19 pulmonary fibrosis; a meta-analysis study. Annals of Medicine and Surgery. NN.5.2022. https://www.sciencedirect.com/science/article/pii/S2049080122003508
SARS-CoV-2 Infection May Present as Acute Hepatitis in Children. Ped Inf Dis J. NN.5.2022. https://journals.lww.com/pidj/fulltext/2021/05000/sars_cov_2_infection_may_present_as_acute.38.aspx
Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens. Lancet Gastroent&Hepatol. 14.5.2022. https://www.sciencedirect.com/science/article/pii/S2468125322001662
Elevated liver enzymes and bilirubin following SARS-CoV-2 infection in children under 10. medRxiv. 14.5.2022. https://www.medrxiv.org/content/10.1101/2022.05.10.22274866v1
Mistä ylikuolleisuusluvut johtuvat? Koronapandemia on sosiaalilääketieteellinen tauti, jonka ilmaantuvuuteen ja haittoihin vaikuttavat niin lääketieteelliset kuin sosiaalisetkin tekijät. Mielipidekirjoitus. Helsingin Sanomat. 14.5.2022. https://www.hs.fi/mielipide/art-2000008812081.html
Tracking covid-19 excess deaths across countries. In many parts of the world, official death tolls undercount the total number of fatalities. Economist. 13.5.2022. https://www.economist.com/graphic-detail/coronavirus-excess-deaths-tracker
You Could Catch Covid Again. And Again. And Even Again. As the virus surges through the US yet again, some people are catching it for a second, third or even fourth time. Bloomberg. 13.5.2022. https://www.bloomberg.com/news/articles/2022-05-13/can-i-get-covid-twice-covid-surges-again-in-us-with-reinfections-rising?
Protecting Children Against Omicron. JAMA. 13.5.2022. https://jamanetwork.com/journals/jama/fullarticle/2792526?guestAccessKey=dce928b5-79bb-4785-978d-20cc768a93cb&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_content=olf&utm_term=051322
Epidemiological update: SARS-CoV-2 Omicron sub-lineages BA.4 and BA.5. ECDC. 13.5.2022. https://www.ecdc.europa.eu/en/news-events/epidemiological-update-sars-cov-2-omicron-sub-lineages-ba4-and-ba5
High population burden of Omicron variant (B.1.1.529) is associated with the emergence of severe hepatitis of unknown etiology in children. Int J Infect Dis. 12.5.2022. https://www.ijidonline.com/article/S1201-9712(22)00290-9/fulltext
Sairaanhoitopiiri suosittaa neljänsiä koronarokotteita nyt myös yli 70-vuotiaille kotihoidon tai omaishoidon piirissä oleville – Tampere aloittaa heti
Jo aiemmin neljänsiä rokotuksia on suositeltu yli 80-vuotiaille. YLE Uutiset. 12.5.2022. https://yle.fi/uutiset/3-12441549
”Koronakuolleisuuden voimakas kasvu jäänyt pimentoon”, sanoo HUSin Lasse Lehtonen – Suomi saattaa tätä menoa kiilata Ruotsin ohi
Lehtosen mukaan väärä tilannekuva voi vähentää ihmisten hakeutumista tehosterokotuksiin. YLE Uutiset. 12.5.2022. https://yle.fi/uutiset/3-12440967
Akuutteja maksatulehduksia havaittu useissa Euroopan maissa, ei yhteyttä koronavirukseen – Suomessa ei viitteitä tapausten lisääntymisestä. Keski-Uusimaa. 12.5.2022. https://www.keski-uusimaa.fi/paikalliset/4600549
Japanese researcher suggests ties between omicron variant and severe hepatitis in children, Japan Times. 12.5.2022. https://www.japantimes.co.jp/news/2022/05/12/national/science-health/japanese-researcher-omicron-hepatitis-children/
Health outcomes in people 2 years after surviving hospitalisation with COVID-19: a longitudinal cohort study. Lancet. Respiratory Medicine. 11.5.2022. https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(22)00126-6/fulltext
May 11-20
Fulminant onset COVID-19: predictors and outcome. BMJ Postgraduate Medical Journal. 10.5.2022. https://pmj.bmj.com/content/early/2022/05/10/postgradmedj-2022-141724
Suun kautta otettavia koronalääkkeitä ei toiveista huolimatta ole saatu Suomeen – neuvottelut junnaavat tai lisänäyttöä vaaditaan
Tuore tutkimustulos kertoo, että koronalääkkeistä remdesiviiri vähentää varmasti kuolleisuutta varhain aloitettuna. Suomalaisprofessori toivoo, että lääkkeitä käyttöönotettaessa niiltä vaadittaisiin laajempaa tutkimusnäyttöä. YLE-Uutiset. 10.5.2022. https://yle.fi/uutiset/3-12430354?utm_source=social-media-share&utm_medium=social&utm_campaign=ylefiapp
Are COVID surges becoming more predictable? New Omicron variants offer a hint. Omicron relatives called BA.4 and BA.5 are behind a fresh wave of COVID-19 in South Africa, and could be signs of a more predictable future for SARS-CoV-2. Nature. 10.5.2022. https://www.nature.com/articles/d41586-022-01240-x?
Effectiveness of influenza vaccination against SARS-CoV-2 infection among healthcare workers in Qatar. medRxiv. 10.5.2022. https://www.medrxiv.org/content/10.1101/2022.05.09.22274802v1.full
New versions of Omicron are masters of immune evasion. Vaccines and prior infection still prevent severe disease from new SARS-CoV-2 strains. Science. 10.5.2022. https://www.science.org/content/article/new-versions-omicron-are-masters-immune-evasion
Covid-19: Fourth dose of mRNA vaccines is safe and boosts immunity, study finds. BMJ. 10.5.2022. https://www.bmj.com/content/377/bmj.o1170?
Feature: How Hong Kong’s vaccination missteps led to the world’s highest covid-19 death rate. Omicron has taken Hong Kong from having one of the lowest covid-19 death rates in the world to having the highest daily death rate per capita. A key reason for this is the island’s handling of vaccination. BMJ. 9.5.2022. https://www.bmj.com/content/377/bmj.o1127?
The route back to 2% inflation − speech by Michael Saunders (impact of COVID & Long COVID on workforce) 9.5.2022. https://www.bankofengland.co.uk/speech/2022/may/michael-saunders-speech-at-the-resolution-foundation-event
Surviving the pandemic is only half the battle: ‘Long COVID’ could affect a billion in just a few years. Fortune. 8.5.2022. https://fortune.com/2022/05/08/surviving-pandemic-half-the-battle-long-covid-growing-public-health-crisis-could-affect-a-billion-in-just-a-few-years/
Suomi kärkisijoilla koronakuolleisuustilastossa – Lasse Lehtonen: ”Epäonnistumiseen on vaikuttanut viisi tekijää”. Kauppalehti. 8.5.2022. https://www.kauppalehti.fi/uutiset/suomi-karkisijoilla-koronakuolleisuustilastossa-lasse-lehtonen-epaonnistumiseen-on-vaikuttanut-viisi-tekijaa/d9ec49a7-8766-46b5-a2a0-f7e737ea4a9c?ref=whatsapp:6978
Estimates of excess mortality for the five Nordic countries during the Covid-19 pandemic 2020-2021. medRxiv. 7.5.2022. https://www.medrxiv.org/content/10.1101/2022.05.07.22274789v1.full.pdf
Prevalence of ongoing symptoms following coronavirus (COVID-19) infection in the UK: 6 May 2022
Estimates of the prevalence of self-reported long COVID and associated activity limitation, using UK Coronavirus (COVID-19) Infection Survey data. Office of National Statistics. 6.5.2022. https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/prevalenceofongoingsymptomsfollowingcoronaviruscovid19infectionintheuk/6may2022
Omicron as severe as other COVID variants -large U.S. study. Reuters. 6.5.2022. https://www.reuters.com/business/healthcare-pharmaceuticals/omicron-severe-previous-covid-variants-large-study-finds-2022-05-05/
SARS-CoV-2 and its variants, but not Omicron, induces severe thymic atrophy and impaired T cell development. Research Square. 5.5.2022. https://www.researchsquare.com/article/rs-1581769/v1
Long COVID or Post-COVID Conditions. CDC. 5.5.2022. https://www.cdc.gov/coronavirus/2019-ncov/long-term-effects/index.html
Mitä maskien hyödyistä oikeasti tiedetään? Maskisuositus päättyi, mutta maski kannattaisikin vaihtaa hengityksensuojaimeen, jos haluaa välttää koronan. Lääkärilehti. 4.5.2022. https://www.laakarilehti.fi/terveydenhuolto/mita-maskien-hyodyista-oikeasti-tiedetaan/?public=e5870728c558cf14d30dff51e32e1935
The Children Left Behind by Long Covid. As the world pretends the pandemic is over, at least a half-million children in the U.S. are struggling with the mysterious disease. Bloomberg. 4.5.2022. https://www.bloomberg.com/news/features/2022-05-04/long-covid-in-kids-has-effects-that-last-beyond-hospital
Long COVID: As much as 75% of hospital patients still not ’fully recovered’. -Researchers followed around 2,000 people who were hospitalized due to a COVID-19-related illness. Of the participants, only 1 in 4 reported feeling fully recovered a year after they were released from the hospital.
Some factors the researchers believe contributed to a poorer outcome include obesity and requiring the use of a ventilator during their hospital stay. MedicalNewsToday. 3.5.2022. https://www.medicalnewstoday.com/articles/long-covid-as-much-as-75-of-hospital-patients-still-not-fully-recovered
SARS-CoV-2 Omicron Variant is as Deadly as Previous Waves After Adjusting for Vaccinations, Demographics, and Comorbidities. Research QSARS-CoV-2 Omicron Variant is as Deadly as Previous Waves After Adjusting for Vaccinations, Demographics, and Comorbidities. Research Square. 2.5.2022. https://www.researchsquare.com/article/rs-1601788/v1
Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses [Marjukka Myllärniemi]. Lancet. 2.5.2022. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00519-0/fulltext
Inflammasome activation in infected macrophages drives COVID-19 pathology. bioRxiv. 1.5.2022. https://www.biorxiv.org/content/10.1101/2021.09.27.461948v2
May 1-10
Fulminant onset COVID- 19: predictors and outcome. BMJ. 30.4.2022. extension://elhekieabhbkpmcefcoobjddigjcaadp/https://pmj.bmj.com/content/postgradmedj/early/2022/05/10/postgradmedj-2022-141724.full.pdf
The 4 physician groups leading the political antivax movement. A physician-led attack on public health is being mediated by the Big 4: The Great Barrington Declaration, America’s Front Line Doctors, Frontline Critical Care Alliance, and the Unity Project. MisinformationKills’s Newsletter. 30.4.2022. https://misinformationkills.substack.com/p/the-4-physician-groups-leading-the?s=r
Protection against Omicron re-infection conferred by prior heterologous SARS-CoV-2 infection, with and without mRNA vaccination. medRxiv. 29.4.2022.https://globalnews.ca/news/8688590/long-covid-symptoms-children/ https://www.medrxiv.org/content/10.1101/2022.04.29.22274455v1.full
Long-term mortality following SARS-CoV-2 infection: A national cohort study from Estonia. Lancet Regional Health Europe, 28.4.2022. https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(22)00087-4/fulltext
South Africa is being hit hard by COVID again. Here is what that means for the US. It’s too soon to know whether the BA.4 and BA.5 omicron variants will take off in the U.S. as they are in South Africa. But some experts are anxious. USA Today. 28.4.2022. https://eu.usatoday.com/story/news/health/2022/04/28/south-africa-omicron-ba-4-ba-5-what-means-us/9553483002/
Monitoring SARS-CoV-2 in air and on surfaces and estimating infection risk in buildings and buses on a university campus. Journal of Exposure Science & Environmental Epidemiology. 27.4.2022. https://www.nature.com/articles/s41370-022-00442-9
Critical weaknesses in shielding strategies for COVID-19. PLOS Global Public Health. 26.4.2022. https://journals.plos.org/globalpublichealth/article?id=10.1371/journal.pgph.0000298
Moderna’s new COVID-19 booster protects better against Omicron and other variants. MedicalNewsToday. 25.4.2022. https://www.medicalnewstoday.com/articles/modernas-new-covid-19-booster-protects-better-against-omicron-other-variants?
COVID-19 and the Brain: The Neuropathological Italian Experience on 33 Adult Autopsies. MDPI (Biomolecules) 25.4.2022. https://www.mdpi.com/2218-273X/12/5/629
Investigation into acute hepatitis of unknown aetiology in children in England. Technical briefing. UK Health Security Agency, 25.4.2022. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1071198/acute-hepatitis-technical-briefing-1_4_.pdf
WHO recommends highly successful COVID-19 therapy (Paxlovid) and calls for wide geographical distribution and transparency from originator. WHO. 22.4.2022. https://www.who.int/news/item/22-04-2022-who-recommends-highly-successful-covid-19-therapy-and-calls-for-wide-geographical-distribution-and-transparency-from-originator
An mRNA vaccine with a twist—it copies itself—protects against COVID-19. Company’s limited data release backs promise of new, lower dose vaccine designed to be easier to distribute and cheaper. Science. 21.4.2022. https://www.science.org/content/article/mrna-vaccine-twist-it-copies-itself-protects-against-covid-19?
Everything You Need to Know About the Hepatitis Outbreak Among Children. Is the number of cases in Israel unusually high, what are the symptoms of the disease and is it linked to the coronavirus? Haaretz explains. Haaretz. 21.4.2022. https://www.haaretz.com/israel-news/everything-you-need-to-know-about-the-hepatitis-outbreak-among-children-1.10754895
Israel Examining 12 Cases of Kids’ Hepatitis After WHO Warning
After 84 cases of hepatitis in children were discovered in the U.K. without a known cause, Israel begins monitoring similar cases in hopes of finding an explanation for the recent surge. Haaretz. 21.4.2022. https://www.haaretz.com/israel-news/israel-examining-12-cases-of-kids-hepatitis-after-who-warning-1.10752779
Kaksi kokenutta lääkäriä vaatii neljänsiä rokotteita entistä nuoremmille – viidessä kuukaudessa koronakuolemia on ollut Suomessa yli 2300. HUSin Eeva Ruotsalainen ja Länsi-Pohjan Markku Broas vaativat neljänsien rokotteiden ikärajan laskemista pikaisella aikataululla. Näin on tehty myös useissa muissa maissa. YLE Uutiset. 21.4.2022. https://yle.fi/uutiset/3-12412961
April 21-30
Ruotsin valtionepidemiologi Anders Tegnell ei saanutkaan töitä WHO:sta. Rokotteiden saannin turvaamiseen liittyvän työpaikan oli tarkoitus sijaita WHO:n päämajassa Sveitsin Genevessä. Helsinngin Sanomat. 20.4.2022. https://www.hs.fi/ulkomaat/art-2000008763814.html
Maskeista luovutaan Helsingin seudun joukkoliikenteessä – Finnair tarkastelee maskivaatimustaan lähiaikoina. Helsingin seudun liikenne luopuu yleisestä maskisuosituksesta. Helsingin Sanomat. 20.4.2022. https://www.hs.fi/kaupunki/art-2000008763129.html
UK to have slowest growth of G7 nations in 2023, says IMF. PM’s claims that Britain has strongest rebound in group undermined by fund’s latest economic forecast (COVID pandemic). Financial Times. 19.4.2022. https://www.ft.com/content/4ac7e454-5a0c-4094-90af-fb54404d45a0
THL:n Mika Salminen tokaisi Ylellä työterveydestä ”suosittu mutta typerä”– ja palautetta vyöryy. Mika Salmisen mielestä terveydenhuoltojärjestelmän pitäisi olla kaikille sama riippumatta siitä, käykö ihminen töissä. Mediuutiset. 19.4.2022. https://www.mediuutiset.fi/uutiset/mu/dd510566-85d2-4472-9165-4e1e81db3909
Global COVID-19 Death Toll May Be Triple the Reported Deaths. JAMA. 19.4.2022. https://jamanetwork.com/journals/jama/fullarticle/2791213?
Pulmonary fibrosis seen in half of COVID-19 survivors. Univadis. 18.4.2022. https://www.univadis.com/viewarticle/pulmonary-fibrosis-seen-in-half-of-covid-19-survivors-76f7a96b-ee38-31c8-9986-f9aa25b835a3?
Six-month sequelae of post-vaccination SARS-CoV-2 infection: A retrospective cohort study of 10,024 breakthrough infections. Brain Behaviour and Immunity. 18.4.2022. https://reader.elsevier.com/reader/sd/pii/S0889159122001118?
Global Prevalence of Post COVID-19 Condition or Long COVID: A Meta-Analysis and Systematic Review. J Infect Dis. 16.4.2022. https://pubmed.ncbi.nlm.nih.gov/35429399/
Vaccines are no match for long Covid. Treating it is science’s next great challenge. Guardian. 16.4.2022. https://www.theguardian.com/commentisfree/2022/apr/16/vaccines-long-covid-science?CMP=Share_AndroidApp_Other
Even mild COVID-19 can cause your brain to shrink. Recent brain imaging shows the disease can cause physical changes equivalent to a decade of aging and trigger problems with attention and memory. Exactly why is still a mystery. National Geographic. 15.4.2022. https://www.nationalgeographic.com/magazine/article/even-mild-covid-19-can-cause-your-brain-to-shrink?
Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland. WHO. 15.4.2022. https://www.who.int/emergencies/disease-outbreak-news/item/acute-hepatitis-of-unknown-aetiology—the-united-kingdom-of-great-britain-and-northern-ireland
FDA authorizes first Covid-19 breath test. CNN health. 15.4.2022. https://edition.cnn.com/2022/04/14/health/covid-breath-test/index.html?
Estimating excess mortality due to the COVID-19 pandemic: a systematic analysis of COVID-19-related mortality, 2020–21. Lancet. 14.4.,2022. https://www.thelancet.com/action/showPdf?pii=S0140-6736%2821%2902796-3
Hundreds are still dying from Covid every day. Why is Paxlovid sitting on shelves? The supply of Pfizer’s highly effective antiviral pill has rapidly increased, but many physicians still aren’t prescribing it. NBCNews.14.4.2022. https://www.nbcnews.com/health/health-news/covid-antiviral-pill-paxlovid-underused-supply-rcna24200
COVID-19 Autopsies Reveal Underreporting of SARS-CoV-2 Infection and Scarcity of Co-infections. Frontiers in Medicine. 14.4.2022. https://www.frontiersin.org/articles/10.3389/fmed.2022.868954/full
SARS-CoV-2 Actively Infects And Kills Lymphoid Cells. Forbes. 14.4.2022. https://www.forbes.com/sites/williamhaseltine/2022/04/14/sars-cov-2-actively-infects-and-kills-lymphoid-cells/?sh=2c22257786b8
Potilaan Lääkärilehti: Neurologian professorin mukaan koronatartunnan välttely on yhä järkevää, Koronatartunnan välttely on neurologian professorin Risto O. Roineen mukaan edelleen järkevää. Roine kommentoi asiaa Potilaan lääkärilehdessä. Kaleva. 14.4.2022. https://www.kaleva.fi/potilaan-laakarilehti-neurologian-professorin-muka/4521049
Unmasked Facies. JAMA. 14.2.2022. https://jamanetwork.com/journals/jama/fullarticle/2791316
Omikron BA.2 on nyt yleisin jätevesien koronavirusmuunnos Koronaviruksen RNA:n kokonaismäärä Suomen jätevesissä on edelleen korkealla tasolla. Mediuutiset. 13.4.2022. https://www.mediuutiset.fi/uutiset/mu/00b5d440-733e-49df-aa28-c181927582c6
Statement on the eleventh meeting of the International Health Regulations (2005) Emergency Committee regarding the coronavirus disease (COVID-19) pandemic. WHO. 13.4.2022. https://www.who.int/news/item/13-04-2022-statement-on-the-eleventh-meeting-of-the-international-health-regulations-(2005)-emergency-committee-regarding-the-coronavirus-disease-(covid-19)-pandemic
COVID-19: “THE ELIMINATION OF THE VIRUS IS ALWAYS POSSIBLE”
Interview with Yaneer Bar-Yam. World Health Network. 12.4.2022. https://www.worldhealthnetwork.global/yaneer-interview
COVID-19: Current cases. Information about confirmed and probable cases of COVID-19 in New Zealand. Ministry of Health. 11.4.2022. https://www.mediuutiset.fi/uutiset/mu/d12f17a8-a11a-4aad-a02a-8c47c99a4834
NHS chiefs call for return of masks and limits on indoor mixing. The NHS Confederation wants a return to mask use. Health chiefs want the government to reconsider its ’living with Covid plan’ and are urging a return to mask use, accusing No10 of abandoning ”any interest in Covid whatsoever.” LBC. 11.4.2022. https://www.lbc.co.uk/news/nhs-chiefs-call-for-return-of-masks-and-limits-on-indoor-mixing/
Postmortem Assessment of Olfactory Tissue Degeneration and Microvasculopathy in Patients With COVID-19. JAMA Neurology. 11.4.2022. https://jamanetwork.com/journals/jamaneurology/fullarticle/2790735
Aivot ottavat koronasta osumaa. Korona ei vanhenna aivoja kymmentä vuotta, vaan kohutussa brittitutkimuksessa havaittiin sen aiheuttavan volyymikatoa aivojen etualaosassa etenkin iäkkäillä. Lääkärilehti. 11.4.2022. https://www.laakarilehti.fi/terveydenhuolto/aivot-ottavat-koronasta-osumaa/
Japan’s Low-Key Covid Campaign Has Lessons for China
The strident efforts in the People’s Republic are in stark contrast to the restrained but more sustainable efforts by its old rival to the east. Bloomberg. 11.4.2022. https://www.bloomberg.com/opinion/articles/2022-04-10/japan-s-low-key-covid-campaign-is-more-sustainable-than-china-s-all-out-efforts
April 11-20
In-person schooling and associated COVID-19 risk in the United States over spring semester 2021. Science Advances. 20.4.2022. https://www.science.org/doi/10.1126/sciadv.abm9128
Erikoislääkäri Maria Juusela pohtii, pitäisikö meillä olla itsenäinen koronapandemian seurantalaskuri? Juusela myös ihmettelee, missä viipyvät päätökset ikäihmisten 4. rokotteista ja kolmas rokotekierros 12–17-vuotiaille? MediUutiset. 10.4.2022. https://www.mediuutiset.fi/uutiset/mu/d12f17a8-a11a-4aad-a02a-8c47c99a4834
The Latest on Long Covid Research with Dr. Iwasaki. YouTube. 7.4.2022. https://www.youtube.com/embed/CF4j-EVPlPU
Use of face masks did not impact COVID-19 incidence among 10–12-year-olds in Finland. medRxiv. 7.4.2022. https://www.medrxiv.org/content/10.1101/2022.04.04.22272833v1
Covid-19: Symptomatic infection with omicron variant is milder and shorter than with delta, study reports. BMJ. 7.4.2022. https://www.bmj.com/content/377/bmj.o922
COVID-19 Linked to Increased Risk of Blood Clots Even Months Later: What to Know. A new study finds that people who had COVID-19 are at increased risk for blood disorders months after their illness.
This may be due to inflammation from the illness.
Getting vaccinated can help protect people from developing blood clots or bleeding disorders after COVID-19. HealthLine. 6.4.2022. https://www.healthline.com/health-news/covid-19-linked-to-increased-risk-of-blood-clots-even-months-later-what-to-know
Post COVID-19 pulmonary fibrosis; a meta-analysis study. Ann Med Surg. 6.4.2022. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983072/
FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation. Nature. 8.4.2022. https://www.nature.com/articles/s41586-022-04702-4
Why the WHO took two years to say COVID is airborne. Early in the pandemic, the World Health Organization stated that SARS-CoV-2 was not transmitted through the air. That mistake and the prolonged process of correcting it sowed confusion and raises questions about what will happen in the next pandemic. Nature. 6.4.2022. https://www.nature.com/articles/d41586-022-00925-7#:~:text=Early%20in%20the%20pandemic%2C%20the,happen%20in%20the%20next%20pandemic.
What triggers severe COVID? Infected immune cells hold clues. Studies have revealed that infected immune cells prompt a massive inflammatory response. Nature. 6.4.2022. https://www.nature.com/articles/d41586-022-00925-7?
Long Covid-19 may remain a chronic condition for millions. CNN. 6.4.2022. https://edition.cnn.com/2022/04/06/health/long-covid-19-what-it-is/index.html?utm_term=1649773240313cb7d3e794e8f&utm_source=cnn_04.12.22+Results+are+In&utm_medium=email&bt_ee=PEXLei5P3p%2BiG1z4Yln2Auu78mQi6iafOQnIivqIAJmUfotwGi0zJPx41Ek%2Fpfri&bt_ts=1649773240315
Exhaled CO2 as a COVID-19 Infection Risk Proxy for Different Indoor Environments and Activities. National Library of Medicine. (Environ Sci Technol Lett) 5.4.2022. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043197/
Protection by a Fourth Dose of BNT162b2 against Omicron in Israel. NEJM. 5.4.2022. https://www.nejm.org/doi/full/10.1056/NEJMoa2201570?query=recirc_mostViewed_railB_article
Glasses and risk of COVID-19 transmission – analysis of the Virus Watch Community Cohort study. medRxiv. 4.4.2022. https://www.medrxiv.org/content/medrxiv/early/2022/04/04/2022.03.29.22272997.full.pdf
Bars, cinemas, gyms: Belgium agrees on ‘ventilation plan’ for public places. The Brussels Times. 4.4.2022. https://www.brusselstimes.com/belgium-news/214866/bars-cinemas-gyms-belgium-agrees-on-ventilation-plan-for-public-places?s=03
Cardiac impairment in Long Covid 1-year post-SARS-CoV-2 infection. medRxiv. 4.4.2022. https://www.medrxiv.org/content/10.1101/2022.04.03.22272610v1
Prof Jeremy Nicholson: the link between Long Covid and heart disease. RNZ. 2.4.2022. https://www.rnz.co.nz/national/programmes/saturday/audio/2018836711/prof-jeremy-nicholson-the-link-between-long-covid-and-heart-disease
What Is The Omicron XE Variant And Why Are Scientists Concerned About Its Rapid Transmission Rate? Medriva. 2.4.2022. https://medriva.com/what-is-the-omicron-xe-variant-and-why-are-scientists-concerned-about-their-rapid-transmission-rates-fueling-the-uk/
What Drives Post-COVID Cognitive Changes? — New research hints at why COVID brain fog may persist. Medpage Today. 1.4.2022. https://www.medpagetoday.com/neurology/generalneurology/97981
Projecting COVID-19 Mortality as States Relax Nonpharmacologic Interventions. JAMA Health Forum. 1.4.2022. https://jamanetwork.com/journals/jama-health-forum/fullarticle/2790812?
Incidence Rates and Clinical Outcomes of SARS-CoV-2 Infection With the Omicron and Delta Variants in Children Younger Than 5 Years in the US. JAMA Pediatrics. 1.4.2022. https://jamanetwork.com/journals/jamapediatrics/fullarticle/2790793?
Analyysi: Korona yhdisti tiedemaailman, Venäjän hyökkäys rikkoi sen jälleen – tieteellä ei ole varaa uuteen kylmään sotaan. Venäjän hallitus on kieltänyt tutkijoitaan osallistumasta kansainvälisiin konferensseihin ja länsimaiset tiedeyhteisöt boikotoivat venäläisiä. Sota on monella alalla katkaissut tutkimuksen, joka luotti yhtenäiseen maailmaan, kirjoittaa toimittaja Johannes Blom. YLE-Uutiset. 1.4.2022. https://yle.fi/uutiset/3-12384327?
April 1 – 10
Diabetes risk rises after COVID, massive study finds
Even mild SARS-CoV-2 infections can amplify a person’s chance of developing diabetes, especially for those already susceptible to the disease. Nature. 31.3.2022. https://www.nature.com/articles/d41586-022-00912-y
How Japan survived covid-19. BMJ. 31.3.2022. https://www.bmj.com/content/376/bmj.o778
Koronakuolemia voitaisiin estää antamalla neljäs annos nopeasti myös alle 80-vuotiaille, sanovat HUSin asiantuntijat. Tehosteannokset olisivat tarpeen erityisesti 70-79-vuotiaiden ikäryhmälle. YLE_Uutiset. 31.3.2022. https://yle.fi/uutiset/3-12384691
SARS-CoV-2 spike protein induces cognitive deficit and anxiety-like behavior in mouse via non-cell autonomous hippocampal neuronal death. Scientific Reports. 31.3.2022. https://www.nature.com/articles/s41598-022-09410-7
Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults. Nature Medicine. 31.3.2022. https://www.nature.com/articles/s41591-022-01780-9
Column: Did Sweden beat the pandemic by refusing to lock down? No, its record is disastrous. Los Angeles Times. 31.3.2022. https://www.latimes.com/business/story/2022-03-31/sweden-covid-policy-was-a-disaster
Diabetes risk rises after COVID, massive study finds. Even mild SARS-CoV-2 infections can amplify a person’s chance of developing diabetes, especially for those already susceptible to the disease. Nature. 31.3.2022. https://www.nature.com/articles/d41586-022-00912-y?
Can you get Covid twice in one month? How soon you can recatch coronavirus and if you can get Omicron again. Omicron has been shown to typically cause less serious illness, but also brings with it an increased risk of reinfection. iNews/Health. 30.3.2022. https://inews.co.uk/news/health/covid-can-get-twice-month-how-soon-catch-coronavirus-again-what-reinfection-explained-1443820
Rapid increase in SARS-CoV-2 seroprevalence during the emergence of Omicron variant, Finland. medRxiv. 30.3.2022. https://www.medrxiv.org/content/10.1101/2022.03.25.22272952v1
Omikron säilyy muovipinnalla pidempään kuin muut koronavariantit, jopa 193 tuntia – Myös ihmisiholla se sinnittelee pisimpään. Kaksi tuoretta aasialaista tutkimusta vertailee koronaviruksen omikron-variantin poikkeuksellista kykyä säilyä erilaisilla pinnoilla elossa. Mediuutiset. 30.3.2022. https://www.mediuutiset.fi/uutiset/mu/1c7262b3-4ebd-43b5-bda3-fd9052f4d743?ref=newsletter:65ee&utm_source=uutiskirje%40mediuutiset.fi&utm_medium=email&utm_campaign=MU-Uutiskirje-laakari
Effect of Early Treatment with Ivermectin among Patients with Covid-19. NEJM. 30.3.2022. https://www.nejm.org/doi/full/10.1056/NEJMoa2115869
Asiantuntijat: Korona ei muutu ehkä koskaan tavalliseksi kausiflunssaksi – tästä se johtuu. Asiantuntijat suhtautuvat epäillen siihen, että koronaviruksesta olisi ainakaan lähiaikoina tulossa ihmisille lievä ja vaaraton tauti. Ilta=sanomat. 30.3.2022. https://www.is.fi/kotimaa/art-2000008714148.html
F.D.A. Allows Second Coronavirus Boosters for Everyone 50 and Older
People in the age group can get the additional shot at least four months after their first booster. Those 12 and older with certain immune deficiencies are also eligible. New York Times. 29.3.2022. https://www.nytimes.com/2022/03/29/us/politics/second-coronavirus-booster-shot.html?referringSource=articleShare
White House Reverts to Air Hygiene in latest efforts to thwart coronavirus. It is pushingh strategies, such as better wir filters in schools and businesses, to help thwart the virus. Washingtonm Post. 29.3.2022. https://www.washingtonpost.com/health/2022/03/29/white-house-covid-strategy-indoor-air-quality/
Risk of SARS-CoV-2 reinfections in children: a prospective national surveillance study between January, 2020, and July, 2021, in England. Lancet. 28.3.2022. https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(22)00059-1/fulltext
Molecular consequences of SARS-CoV-2 liver tropism. Nature Metabolism. 28.3.2022. https://www.nature.com/articles/s42255-022-00552-6.
SvD: Förvirring kring Tegnells nya jobb på WHO – jobbet finns inte. HBL. 28.3.2022. https://www.hbl.fi/artikel/forvirring-kring-tegnells-nya-jobb-pa-who-jobbet-finns-inte/?
Fourth Vaccine Reduces Risk of Dying From COVID by 78 Percent, Israeli Study Finds. As omicron’s BA.2 variant is fueling a spike in COVID-19 infections, the latest large-scale study by an Israeli HMO suggests that a fourth dose reduces both the risk of infection and severe illness. Haaretz. 26.3.2022. https://www.haaretz.com/israel-news/fourth-vaccine-reduces-risk-of-dying-from-covid-by-78-percent-israeli-study-finds-1.10700268
What to know about flying during the COVID-19 pandemic. Medical News Today. 28.3.2022. https://www.medicalnewstoday.com/articles/flying-during-covid
Fourth Vaccine Reduces Risk of Dying From COVID by 78 Percent, Israeli Study Finds. As omicron’s BA.2 variant is fueling a spike in COVID-19 infections, the latest large-scale study by an Israeli HMO suggests that a fourth dose reduces both the risk of infection and severe illness. Haaretz. 26.3.2022. https://www.haaretz.com/israel-news/fourth-vaccine-reduces-risk-of-dying-from-covid-by-78-percent-israeli-study-finds-1.10700268
SARS-CoV-2 co-infection with influenza viruses, respiratory syncytial virus, or adenoviruses. Lancet. 25.3.2022. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00383-X/fulltext
Can drugs reduce the risk of long COVID? What scientists know so far
Researchers are trying to establish whether existing COVID-19 vaccines and treatments can prevent lasting symptoms. nature. 25.3.2022. https://www.nature.com/articles/d41586-022-00823-y?fbclid=IwAR0rO3bh97jIMiIucaYJHf5yhtOTpWE7vFFDveiEUnT8dZE-CWDSS2FL3Ng
Evusheld (tiksagevimabi/silgavimabi) Yleistiedot Evusheld-valmisteesta sekä siitä, miksi se on hyväksytty EU:ssa (COVID-19 ehkäisylääke). EMA. 25.3.2022. https://www.ema.europa.eu/en/documents/overview/evusheld-epar-medicine-overview_fi.pdf
SARS-CoV-2 infects and replicates in photoreceptor and retinal ganglion cells of human retinal organoids. Stem Cell Reports. 24.3.2022. https://www.cell.com/stem-cell-reports/fulltext/S2213-6711(22)00104-7
Second Booster Vaccine and Covid-19 Mortality in Adults 60 to 100 Years Old. Research Square. 24.3.2022. https://assets.researchsquare.com/files/rs-1478439/v1/24514bba-2c9d-4add-9d8f-321f610ed199.pdf?c=1648141784
Evaluation of airborne transmission risk in university towns based on IEQ surveys. National Library of Medicine. (Energy and Built Environment) 23.3.2022. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942440/
Burden of PCR-Confirmed SARS-CoV-2 Reinfection in the U.S. Veterans Administration, March 2020 – January 2022. medRxiv. 23.3.2022. https://www.medrxiv.org/content/10.1101/2022.03.20.22272571v1.full.pdf
Robust, persistent adaptive immune responses to SARS-CoV-2 in the oropharyngeal lymphoid tissue of children. Research Square. 23.4.2022. https://www.researchsquare.com/article/rs-1276578/v1
Airborne transmission: Are CO2 monitors a long term solution or “pandemic hack?” BMJ. 23.3.2022. https://www.bmj.com/content/376/bmj.o736?
Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 (PIMS-TS): Prospective, national surveillance, United Kingdom and Ireland, 2020. Lancet. 22.3.2022. https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(21)00052-1/fulltext#:~:text=There%20was%20a%20strong%20geographical,SARS%2DCoV%2D2%20antibodies
Evaluation of science advice during the COVID-19 pandemic in Sweden. Nature / Humanities & Sociall Sciences Communications. 22.3.2022. https://www.nature.com/articles/s41599-022-01097-5
Italian study shows ventilation can cut school COVID cases by 82%. Reuters. 22.3.2022. https://www.reuters.com/world/europe/italian-study-shows-ventilation-can-cut-school-covid-cases-by-82-2022-03-22/
Effectiveness of a second BNT162b2 booster vaccine against hospitalization and death from COVID-19 in adults aged over 60 years. Nature Medicine. 22.3.2022. https://www.nature.com/articles/s41591-022-01832-0_reference.pdf
Myocarditis and pericarditis after COVID-19 vaccination: clinical management guidance for healthcare professionals. Gov.UK. 21.3.2022. https://www.gov.uk/government/publications/myocarditis-and-pericarditis-after-covid-19-vaccination/myocarditis-and-pericarditis-after-covid-19-vaccination-guidance-for-healthcare-professionals
March 21-31
Ivermectin Didn’t Reduce Covid-19 Hospitalizations in Largest Trial to Date
Patients who got the antiparasitic drug didn’t fare better than those who received a placebo. Wall Street Journal. 18.3.2022. https://www.wsj.com/articles/ivermectin-didnt-reduce-covid-19-hospitalizations-in-largest-trial-to-date-11647601200
Omicron survives longer on some surfaces, studies find. That may help explain why it’s more contagious, but it’s no reason to panic. CNN Health. 18.3.2022. https://edition.cnn.com/2022/03/18/health/omicron-surfaces-studies/index.html?
Infektiolääkäri kirjoitti kriittisen kirjan koronan hoidosta – Rajoitukset aiheuttaneet vakavia terveysongelmia ja taloudellisia tappioita.
Uutuuskirja koronapandemiasta Suomessa: Taudin torjuntakeinot aiheuttaneet vakavia terveydellisiä ja taloudellisia haittoja. Kirjan mukaan paljossa on onnistuttu, mutta pelon lietsominen ja ylimitoitetut rajoitukset ajoittaisine täyssulkuineen ovat aiheuttaneet vakavia terveysongelmia ja taloudellisia tappioita. Mediuutiset. 17.3.2022. https://www.mediuutiset.fi/uutiset/mu/a6ea7482-cf62-4c5e-b245-c63603c7a8f7?
FACT SHEET: Biden Administration Launches Effort to Improve Ventilation and Reduce the Spread of COVID-19 in Buildings. White House. 17.3.2022. https://www.whitehouse.gov/briefing-room/statements-releases/2022/03/17/fact-sheet-biden-administration-launches-effort-to-improve-ventilation-and-reduce-the-spread-of-covid-19-in-buildings/
America Is Zooming Through the Pandemic Panic-Neglect Cycle. All epidemics trigger the same Sisyphean cycle of panic and neglect. Even so, that cycle isn’t meant to spin this quickly. Atlantic. 17.3.2022. https://www.theatlantic.com/health/archive/2022/03/congress-covid-spending-bill/627090/
‘Heartbreaking’: How long COVID is impacting children. Global News. 16.3.2022. https://globalnews.ca/news/8688590/long-covid-symptoms-children/
Global Prevalence of Post COVID-19 Condition or Long COVID: A Meta-Analysis and Systematic Review. J Infect Dis. 16.3.2022. https://pubmed.ncbi.nlm.nih.gov/35429399/ COMPLETE https://watermark.silverchair.com/jiac136.pdf
1 in 4 symptomatic children get long COVID, a new study finds. What are the symptoms? EuroNewsNext. 16.3.2022. https://www.euronews.com/next/2022/03/15/long-covid-has-been-found-in-1-in-4-symptomatic-children-a-new-study-finds-what-are-the-sy
Fevers, convulsions seen more in children during omicron wave: Japan Pediatric Society. The Mainichi. 16.3.2022. https://mainichi.jp/english/articles/20220316/p2a/00m/0na/006000c
Comparative analysis of the risks of hospitalisation and death associated with SARS-CoV-2 omicron (B.1.1.529) and delta (B.1.617.2) variants in England: a cohort study. Lancet. 16.3.2022. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00462-7/fulltext
‘Heartbreaking’: How long COVID is impacting children. Global News. 17.3.2022. https://globalnews.ca/news/8688590/long-covid-symptoms-children/
THE COLOR OF CORONAVIRUS:
COVID-19 DEATHS BY RACE AND ETHNICITY IN THE U.S. APM Research Lab. 15.3.2022. https://www.apmresearchlab.org/covid/deaths-by-race
Airborne Transmission of SARS-CoV-2 Delta Variant within Tightly Monitored Isolation Facility, New Zealand (Aotearoa). Emerging Infectious Diseases. NN.3 2022. https://doi.org/10.3201/eid2803.212318
Fatigue and cognitive impairment in Post-COVID-19 Syndrome: A systematic review and meta-analysis. Brain, Behaviour, and Immunity. NN.3.2022. https://www.sciencedirect.com/science/article/pii/S0889159121006516
COVID and the Heart: It Spares No One. Research now tells us that COVID doesn’t discriminate when it comes to heart problems. Johns Hopkins. 14.3.2022. https://publichealth.jhu.edu/2022/covid-and-the-heart-it-spares-no-one
Antigenic evolution will lead to new SARS-CoV-2 variants with unpredictable severity. Nature Reviews. Microbiology. 14.3.2022. ttps://www.nature.com/articles/s41579-022-00722-z
Effect of Sotrovimab on Hospitalization or Death Among High-risk Patients With Mild to Moderate COVID-19. A Randomized Clinical Trial. JAMA. 14.3.2022. https://jamanetwork.com/journals/jama/fullarticle/2790246?
Long COVID in Children and Adolescents: A Systematic Review and Meta-analyses. medRxiv. 13.3.2022. https://www.medrxiv.org/content/10.1101/2022.03.10.22272237v1
One-third of all US child Covid deaths occurred during Omicron surge.
Children seem to be facing increasing risks as mask mandates are abandoned and vaccination rates stall. Guardian. 11.3.2022. https://www.theguardian.com/world/2022/mar/11/us-child-covid-deaths-omicron-surge?CMP=Share_iOSApp_Other
ACE2-independent infection of T lymphocytes by SARS-CoV-2. Nature. 11.3.2022. https://www.nature.com/articles/s41392-022-00919-x
March 11-20
We cannot afford to repeat these four pandemic mistakes. BMJ. 10.3.2022. https://www.bmj.com/content/376/bmj.o631
Estimating excess mortality due to the COVID-19 pandemic: a systematic analysis of COVID-19-related mortality, 2020–21. Lancet. 10.3.2022. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)02796-3/fulltext
Mandatory masking in schools reduced COVID-19 cases during Delta surge. NIH-funded study compared more than 1.1 million students across nine states. NIH News Releases. 10.3.2022. https://www.nih.gov/news-events/news-releases/mandatory-masking-schools-reduced-covid-19-cases-during-delta-surge?
Perspectives: The “Wolf” Is Indeed Coming: Recombinant “Deltacron” SARS-CoV-2 Detected. CCDC Weekly. 9.3.2022. https://weekly.chinacdc.cn/en/article/doi/10.46234/ccdcw2022.054
School Masking Policies and Secondary SARS-CoV-2 Transmission. Pediatrics. 9.3.2022. https://publications.aap.org/pediatrics/article/doi/10.1542/peds.2022-056687/185379/School-Masking-Policies-and-Secondary-SARS-CoV-2
Sveriges statsepidemiolog Anders Tegnell slutar – får jobb hos WHO. Hufvudstadsbladet. 9.3.3033. https://www.hbl.fi/artikel/sveriges-statsepidemiolog-anders-tegnell-slutar-far-jobb-hos-who/
SARS-CoV-2 is associated with changes in brain structure in UK Biobank. Nature. 7.3.2022. https://www.nature.com/articles/s41586-022-04569-5
Aamulehti: Aki Lindén huolissaan koronarokotustahdin hiipumisesta.
Aki Lindén muistuttaa Aamulehdessä, että koronaa on edelleen liikkeellä. Iltalehti. 5.3.2022. https://www.iltalehti.fi/koronavirus/a/a554622b-41ec-4f0d-82ef-f64b7d73bfa8
How a nondescript box has been saving lives during the pandemic – and revealing the power of grassroots innovation. The Conversation 3.2.2022. https://theconversation.com/how-a-nondescript-box-has-been-saving-lives-during-the-pandemic-and-revealing-the-power-of-grassroots-innovation-176779?
The Challenge of Debunking Health Misinformation in Dynamic Social Media Conversations: Online Randomized Study of Public Masking During COVID-19. J Med Internet Res. 2.3.2022. https://pubmed.ncbi.nlm.nih.gov/35156933/
The White House unveils a new Covid strategy, but it will need congressional funding. NewYork Times. 2.3.2022. https://www.nytimes.com/live/2022/03/02/world/covid-19-tests-cases-vaccine?referringSource=articleShare#biden-announces-initiative-to-pair-coronavirus-tests-with-treatment
How ventilation, filtration, and humidity may prevent coronavirus transmission. Medical News Today. 2.3.2022. https://www.medicalnewstoday.com/articles/how-ventilation-filtration-and-humidity-may-prevent-coronavirus-transmission
Molecular imaging findings on acute and long-term effects of COVID-19 on the brain: A systematic review. JNM. 1.3.2022. https://jnm.snmjournals.org/content/early/2022/02/17/jnumed.121.263085
March 1 – 10
Koronapandemian alkuperä yhä varmempi: tutkimusten mukaan tartunnat lähtivät eläintorilta kahteen otteeseen, väli-isäntänä saattoi olla supikoira
Kahdessa kansainvälisessä ja yhdessä kiinalaisessa tutkimuksessa on saatu vahvaa näyttöä siitä, että SARS-CoV-2 tarttui torilla myydyistä eläimistä. Hypoteesi laboratoriosta viruksen syntypaikkana hiipuu. YLE Uutiset 28.2.2022. https://yle.fi/uutiset/3-12336380?utm_source=newsletter&utm_medium=email&utm_campaign=scienceweekly&utm_content=2022-03-06
Wuhan market was epicentre of pandemic’s start, studies suggest
Report authors say that the coronavirus SARS-CoV-2 jumped to people from animals sold at the market on two occasions in late 2019 — but some scientists want more definitive evidence. Nature. 27.2.2022. https://www.nature.com/articles/d41586-022-00584-8?
The role of outdoor and indoor air quality in the spread of SARS-CoV-2: Overview and recommendations by the research group on COVID-19 and particulate matter (RESCOP commission). National Library of Medicine. (Environ Res) 26.2.2022. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881809/
Comparative effectiveness of N95, surgical or medical, and non-medical facemasks in protection against respiratory virus infection: A systematic review and network meta-analysis. Wiley Online Library. 26.2.2022. https://onlinelibrary.wiley.com/doi/10.1002/rmv.2336
Käännettä parempaan ei koronatilanteessa vielä nähdä – teho-osastolla tilanne oli perjantaina Satakunnassa koko epidemian pahin. Perjantaina hoidossa oli lyhyen ajan jopa viisi koronapotilasta yhtä aikaa. Se on enemmän kuin kertaakaan koko epidemian aikana. Satakunnan kansa. 25.2.2022. https://www.satakunnankansa.fi/koronavirus/art-2000008644315.html
Hus: Kasvomaskisuositus jatkunee vielä kuukausia. Husin Markku Mäkijärven mukaan suojautuminen koronavirustartuntoja vastaan vain korostuu, kun rajoituksia puretaan ja ihmisten kohtaamiset lisääntyvät. Helsingin Sanomat. 25.2.2022. https://www.hs.fi/kaupunki/art-2000008636704.html
NIH launches new initiative to study “Long COVID”. The NIH Director. 23.2.2022. https://www.nih.gov/about-nih/who-we-are/nih-director/statements/nih-launches-new-initiative-study-long-covid
Koronatartunnat ovat hidastaneet koronarokotustahtia. Koronarokotuksia annetaan nyt vain kymmenes osa siitä, mitä annettiin vuoden alussa. YLE Uutiset. 23.2.2022. https://yle.fi/uutiset/3-12329829
Coronavirus vaccine protection was much weaker against omicron, data shows. Washington Post. 23.2.2022. https://www.washingtonpost.com/health/interactive/2022/vaccine-omicron-effectiveness/?itid=hp_pandemic
Genomic assessment of quarantine measures to prevent SARS-CoV-2 importation and transmission. Nature Communications. 23.2.2022. https://www.nature.com/articles/s41467-022-28371-z
Persisting pulmonary dysfunction in pediatric post-acute Covid-19. medRxiv. 22.2.2022. https://www.medrxiv.org/content/10.1101/2022.02.21.22270909v1
When Finland Decided to Open Up: A Behavioural Scientist’s Perspective. Matti Heino blog. 21.2.2022. https://mattiheino.com/2022/02/21/let-me-be-your-deja-vu/
February 21 – 28
Hemliga dokument avslöjar strategin. Svenska Dagbladet. 20.2.2022. https://www.svd.se/hemliga-dokument-avslojar-strategin
Opinion: After the pandemic, long covid may unleash a tidal wave of health troubles. Washington Post. 20.2.2022. https://www.washingtonpost.com/opinions/2022/02/20/long-covid-may-unleash-health-troubles-after-pandemic/
How Long Covid Exhausts the Body. New York Times. 19.2.2022. https://www.nytimes.com/interactive/2022/02/19/science/long-covid-causes.html
Vil at koronasyke barn skal gå på skolen. Barn som kan smitte andre med korona kan være på skolen dersom allmenntilstanden er god. Regjeringen har gjort denne lettelsen i tiltak av hensyn til barn og unge. NRK. 18.2.2022. https://www.nrk.no/norge/vil-at-koronasyke-barn-skal-ga-pa-skolen-1.15857082
Uusi koronatrendi: Lapsipotilaiden määrä sairaaloissa kasvaa Ruotsissa ja Norjassa – tutkimuksen mukaan lapset herkempiä omikronille kuin deltalle
Yhdysvaltalaistutkimuksen mukaan omikroniin sairastuneet lapset joutuivat sairaalahoitoon nelinkertaisesti deltamuunnokseen verrattuna. YLE -Uutiset. 18.2.2022. https://yle.fi/uutiset/3-12322753
Uusi koronatrendi: Lapsipotilaiden määrä sairaaloissa kasvaa Ruotsissa ja Norjassa – tutkimuksen mukaan lapset herkempiä omikronille kuin deltalle
Yhdysvaltalaistutkimuksen mukaan omikroniin sairastuneet lapset joutuivat sairaalahoitoon nelinkertaisesti deltamuunnokseen verrattuna. YLE Uutiset. 18.2.2022. https://yle.fi/uutiset/3-12322753
As BA.2 subvariant of Omicron rises, lab studies point to signs of severity. CNN Health.18.2.2022. https://edition.cnn.com/2022/02/17/health/ba-2-covid-severity/index.html
Waning 2-Dose and 3-Dose Effectiveness of mRNA Vaccines Against COVID-19–Associated Emergency Department and Urgent Care Encounters and Hospitalizations Among Adults During Periods of Delta and Omicron Variant Predominance — VISION Network, 10 States, August 2021–January 2022. CDC MMWR. 18.2.2022. https://www.cdc.gov/mmwr/volumes/71/wr/mm7107e2.htm?s_cid=mm7107e2_w
’I’m an Olympic Athlete. Due to Long COVID, Now I Struggle to Walk Up a Flight of Stairs’. For COVID-19 long haulers, recovery is slow. New research may, however, explain their suffering and point to new avenues for treatment. Everyday Health. 18.2.2022. https://www.everydayhealth.com/coronavirus/mitochondrial-dysfunction-may-be-to-blame-in-long-covid-19/
Estimates of SARS-CoV-2 Omicron Variant Severity in Ontario, Canada. JAMA. 17.2.2022. https://jamanetwork.com/journals/jama/fullarticle/2789408?
US has suffered more than 1m excess deaths during pandemic, CDC finds
The latest statistic hints at the breadth of Covid-19’s impact on health in the United States. Guardian 17.2.2022. https://www.theguardian.com/world/2022/feb/17/us-excess-deaths-pandemic-cdc
Estimates of SARS-CoV-2 Omicron Variant Severity in Ontario, Canada. JAMA. 17.2.2022. https://jamanetwork.com/journals/jama/fullarticle/2789408
Do masks really harm kids? Here’s what the science says. As more states drop mask mandates, experts explain why keeping them on in schools is still a smart move for families and teachers. National Geographic 17.2.2022. https://www.nationalgeographic.com/science/article/do-masks-really-harm-kids-heres-what-the-science-says
Koronavirustippoja laitettiin vapaaehtoisten nenään – tulokset yllättivät. Miksi toiset ovat alttiimpia tartunnalle kuin toiset, ihmettelevät tutkijat. Ilta=sanomat. 17.2.2022. https://www.is.fi/kotimaa/art-2000008620645.html
Grafiikat näyttävät selkeän käänteen epidemian vaarallisuudessa tammikuussa – katso oman ikäryhmäsi tiedot. Vaikka tartuntojen ilmaantuvuus moninkertaistui tammikuussa, kuolemien ilmaantuvuus jopa laski joissain ryhmissä, selviää THL:n uusista tiedoista. Helsingin Sanomat. 17.2.2022. https://www.hs.fi/kotimaa/art-2000008617430.html?
STM:n ja THL:n tilannekatsaus koronavirustílanteesta. Valtioneuvosto. 17.2.2022. https://stm.fi/documents/1271139/110045675/STM+THL+VM+mediainfo17.2.22.FINAL.pdf/
Pandemics disable people — the history lesson that policymakers ignore
Influenza, polio and more have shown that infections can change lives even decades later. Why the complacency over possible long-term effects of COVID-19?. Nature. 16.2.2022. https://www.nature.com/articles/d41586-022-00414-x?
Risks of mental health outcomes in people with covid-19: cohort study. BMJ. 16.2.2022. https://www.bmj.com/content/376/bmj-2021-068993?
Mask Effectiveness for Preventing Secondary Cases of COVID-19, Johnson County, Iowa, USA. CDC Emerging Infectious Diseases, nn.1.2022. https://wwwnc.cdc.gov/eid/article/28/1/21-1591_article
Increased Potency and Breadth of SARS-CoV-2 Neutralizing Antibodies After a Third mRNA Vaccine Dose. bioRxiv. 15.2.2022. https://www.biorxiv.org/content/10.1101/2022.02.14.480394v1
”Det mest anständiga är att åtalet läggs ner”. Jag var en av dem som erbjöds förmånen att bli testad, skriver Sven Britton, professor emeritus, om att åtal väckts för en testning för bestämning av antikroppar mot sars-cov-2. (1 kommentar). Dagens Medicin. 15.2.2022. https://www.dagensmedicin.se/opinion/debatt/det-mest-anstandiga-ar-att-atalet-laggs-ner/
Ilmahygienia suojaa koronatartunnoilta. Ilmavälitteisen tartunnan riskiä voidaan vähentää tieteen ja teknologian tuomien ratkaisujen avulla. Lääkärilehti. 14.2.2022. https://www.laakarilehti.fi/kliininen-tyo/ilmahygienia-suojaa-koronatartunnoilta/?public=c118ba0e51b2a0f8429a4b19c5e7a7df
CDC: COVID-19 Booster Effectiveness Wanes After Four Months.
The agency also finds that third shots prevented hospitalizations during the Omicron wave.The Scientist. 14.2.2022. https://www.the-scientist.com/news-opinion/cdc-covid-19-booster-effectiveness-wanes-after-four-months-69703?
FEATURE: Reduced brain function, immune disorder a possibility of ”long COVID”. Kyodo News. 14.2.2022. https://english.kyodonews.net/news/2022/02/263518f1cd8b-feature-reduced-brain-function-immune-disorder-a-possibility-of-long-covid.html
Tutkijat varoittavat pandemian jälkeisestä sydänpommista: Riskit koholla vielä vuosi infektion jälkeen. MTV-Uutiset 12.2.2021. https://www.msn.com/fi-fi/terveysjafitness/hyvinvointi/tutkijat-varoittavat-pandemian-j%C3%A4lkeisest%C3%A4-syd%C3%A4npommista-riskit-koholla-viel%C3%A4-vuosi-infektion-j%C3%A4lkeen/ar-AATJ1uJ?ocid=winp-sf
Effectiveness of Face Mask or Respirator Use in Indoor Public Settings for Prevention of SARS-CoV-2 Infection — California, February–December 2021. CDC MMWR. 11.2.2022. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830622/
Desinfioivaa UV-valaistusta voidaan käyttää myös ihmisten läsnä ollessa. Covid-19-pandemia on vauhdittanut UV-valoon perustuvan desinfiointiteknologian kehitystä ja käyttöönottoa. Mediuutiset. 11.2.2022. https://www.mediuutiset.fi/uutiset/mu/50a72e39-7b3c-402b-8d5a-92170a0ebcc5?
Academics: Viral Evolution Scenarios, 10 February 2022. Gov.UK. 11.2.2022. https://www.gov.uk/government/publications/academics-viral-evolution-scenarios-10-february-2022
THL: Koronastrategiaan muutos – Neljäs annos ensisijaisesti vain riskiryhmille. Neljäs rokoteannos ei toisi merkittävää lisähyötyä koko väestölle. Suoja vakavalta taudilta säilyy hyvänä kolmannen annoksen jälkeen myös omikrontartunnoissa. Sosiaali- ja terveydenhuollon henkilöstön rokotukset ovat yhä lääketieteellisesti perusteltuja. Mediuutiset. 11.2.2022. https://www.mediuutiset.fi/uutiset/thl-koronastrategiaan-muutos-neljas-annos-ensisijaisesti-vain-riskiryhmille/c1ff347d-76fc-40c8-b79b-e11ea5bcf9db
February 11 – 20
Weekly death statistics [31 European Countries]. Eurostat. 10.2.2021. https://ec.europa.eu/eurostat/statistics-explained/index.php?title=Weekly_death_statistics#Data_sources
Heart-disease risk soars after COVID — even with a mild case
Massive study shows a long-term, substantial rise in risk of cardiovascular disease, including heart attack and stroke, after a SARS-CoV-2 infection. Nature. 10.2.2022. https://www.nature.com/articles/d41586-022-00403-0
Risk of persistent and new clinical sequelae among adults aged 65 years and older during the post-acute phase of SARS-CoV-2 infection: retrospective cohort study. BMJ. 9.2.2022. https://www.bmj.com/content/376/bmj-2021-068414
Omicron Has Been Found in Deer—That Should Worry Us. TIME. 9.2.2022. https://time.com/6146253/omicron-deer-covid-19/
Perspective SARS-CoV-2 infections in children: Understanding diverse outcomes. Immunity (Cell). 8.2.2022. https://www.cell.com/action/showPdf?pii=S1074-7613%2822%2900043-7
Tyypin 1 diabetes on lisääntynyt korona-aikana Helsingissäkin. Syy on epäselvä ja vaatii lisätutkimuksia, mutta koronapandemiaan on ajallinen yhteys. Lääkärilehti. 8.2.2022. https://www.laakarilehti.fi/tieteessa/tyypin-1-diabetes-on-lisaantynyt-korona-aikana-helsingissakin/?
Long-term cardiovascular outcomes of COVID-19. Nature Medicine. 7.2.2022. https://www.nature.com/articles/s41591-022-01689-3
Host genomes for the unique SARS-CoV-2 variant leaked into Antarctic soil metagenomic sequencing data. Research Square. 7.2.2022. https://www.researchsquare.com/article/rs-1330800/v1
Antihistamines for Postacute Sequelae of SARS-CoV-2 Infection. The Journal for Nurse Practitioners. 7.2.2022. https://www.sciencedirect.com/science/article/pii/S155541552100547X
Rapid and ultrasensitive electromechanical detection of ions, biomolecules and SARS-CoV-2 RNA in unamplified samples, Nature Biomedical Engineering. 7.2.2022. https://www.nature.com/articles/s41551-021-00833-7?
Long-term cardiovascular outcomes of COVID-19. Nature Medicine. 7.2.2022. https://www.nature.com/articles/s41591-022-01689-3
Päivittyvä seuranta: Sairaanhoitopiirit tyrmäävät koululaisten säännöllisen kotitestauksen | Australia avaa rajansa helmikuun lopulla | Turkin presidentillä koronatartunta
Kerromme uusimmat tiedot koronaviruksesta tässä artikkelissa. YLE-Uutiset. 7.2.2022. https://yle.fi/uutiset/3-11942036?utm_source=social-media-share&utm_medium=social&utm_campaign=ylefiapp
Brief incubation, high viral shedding: COVID-19 human challenge trial results. Medical News Today. 4.2.2022. https://www.medicalnewstoday.com/articles/brief-incubation-high-viral-shedding-covid-19-human-challenge-trial-results?
Effectiveness of Face Mask or Respirator Use in Indoor Public Settings for Prevention of SARS-CoV-2 Infection — California, February–December 2021. CDC Morbidity and Mortality Weekly Report. 4.2.2022. https://www.cdc.gov/mmwr/volumes/71/wr/mm7106e1.htm
Alzheimer’s-like changes found in COVID patients’ brains; flu shot, mRNA booster safe together. Reuters. 4.2.2022. https://www.reuters.com/business/healthcare-pharmaceuticals/alzheimers-like-changes-found-covid-patients-brains-flu-shot-mrna-booster-safe-2022-02-04/
Complications Following SARS-CoV-2 Infection in Victoria, Australia: A Record Linkage Study. SSRN (Lancet). 3.2.2022. https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4025054
SARS-CoV-2 Infections in Close Contacts of Positive Cases in the Olympic and Paralympic Village at the 2021 Tokyo Olympic and Paralympic Games. JAMA. 3.2.2022. https://jamanetwork.com/journals/jama/fullarticle/2788895?
Pre-infection 25-hydroxyvitamin D3 levels and association with severity of COVID-19 illness. OLOS One. 3.2.2022. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0263069
Tutkimus: Koronavirus voi tarttua yhdestä pisarasta. Tutkijoiden mukaan kokeiden perusteella tehtiin rohkaisevia havaintoja. Iltalehti. 3.2.2022. [ep’äeettinen tutkimus] https://www.iltalehti.fi/ulkomaat/a/4db7f55f-75d2-401b-9fab-bed077f38095
Prevalence of ongoing symptoms following coronavirus (COVID-19) infection in the UK. ONS. 3.2.2021. https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/datasets/alldatarelatingtoprevalenceofongoingsymptomsfollowingcoronaviruscovid19infectionintheuk?s=09
Miksi rajoituksia puretaan, vaikka koronakuolemia kirjataan yhä kymmeniä viikossa? – ”Ei voida ajatella, että kukaan ei saa Suomessa koskaan kuolla mihinkään”, sanoo THL:n Salminen. Yhä pienempi osa koronatartunnan saaneista kuolee tautiin. Aamulehti. 2.2.2022. https://www.aamulehti.fi/koronavirus/art-2000008583714.html
Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge. [Alexander van Assendelft: an unethical human experiment] Research Square. 1.2.2022. https://www.researchsquare.com/article/rs-1121993/v1
Model-Estimated Association Between Simulated US Elementary School-Related SARS-CoV-2 Transmission, Mitigation Interventions, and Vaccine Coverage Across Local Incidence Levels. JAMA. 1.2.2022. https://pubmed.ncbi.nlm.nih.gov/35157056/
Moni uskoo, että Suomessa on tiukemmat koronarajoitukset kuin muualla – tarkistimme faktat, ja asia on lähes päinvastoin. Tämä juttu kertoo, miten Suomen tämänhetkiset rajoitukset vertautuvat Tanskaan, Saksaan, Englantiin ja Italiaan. Tällä hetkellä yhteiskuntaa avataan osassa Euroopan maita Suomea rivakammin. YLE-Uutiset. 1.2.2022. https://yle.fi/uutiset/3-12297246?utm_source=newsletter&utm_medium=email&utm_campaign=newsdaily&utm_content=2022-02-02
Koronakuolemien määrä kasvaa nopeasti – kysyimme, miksi THL laskee lukuihin muitakin kuin selkeitä koronataudin aiheuttamia kuolemia. Koronaan liittyvien kuolemien määrä ylittää pian 2 000:n rajapyykin. Suurin kuolleisuus on iäkkäillä rokottamattomilla. THL kirjaa koronakuolemiksi kuolemat, jotka ovat tapahtuneet 30 vuorokauden aikana tartunnasta. YLE-Uutiset. 1.2.2022. https://yle.fi/uutiset/3-12296560?utm_source=newsletter&utm_medium=email&utm_campaign=newsdaily&utm_content=2022-02-02
High Rates of Rapid Antigen Test Positivity After 5 days of Isolation for COVID-19. medRxiv. 1.2.2022. https://www.medrxiv.org/content/10.1101/2022.02.01.22269931v1.full.pdf
Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge. In Review.1.2.2022. https://www.researchsquare.com/article/rs-1121993/v1
February 1 – 10
It’s a delusion to think mass spread of Omicron will end the pandemic.Globe and Mail. 31.1.2022. https://www.theglobeandmail.com/opinion/article-its-a-delusion-to-think-mass-spread-of-omicron-will-end-the-pandemic/
Transmission of SARS-CoV-2 Omicron VOC subvariants BA.1 and BA.2: Evidence from Danish Households. medRxiv. 30.1.2022. https://www.medrxiv.org/content/10.1101/2022.01.28.22270044v1.full
Russia Sees Record Population Decline As Excess Deaths Hit 1M. Russia experienced its largest population decline in 2021 since the end of the Soviet Union. Moscow Times. 29.1.2022. https://www.themoscowtimes.com/2022/01/28/russias-pandemic-excess-death-toll-almost-1m-a76194
37,000 People Already Received 4th Vaccination in Hungary. Hungary today. 28.1.2022. https://hungarytoday.hu/coronavirus-covid-19-vaccines-fourth-dose-jab-booster/
Covid-19: Antibody “signature” could predict risk of long covid. BMJ. 28.1.2022. https://www.bmj.com/content/376/bmj.o245?
The COVID Project: Coronavirus in Kids Tracking and Education Project. 28.1.2022. https://www.covkidproject.org/
Nämä keinot ovat vanhentuneet koronan torjunnassa, professori sanoo – tässä pätevät
Moni lotraa edelleen käsidesin kanssa, vaikka oleellisempaa omikronin leviämisen ehkäisemisessä olisi maskin käyttäminen oikein. Iltalehti. 28.1.2022. https://www.iltalehti.fi/terveysuutiset/a/4beeae55-439a-4367-8762-24239d61be4a?
Coronaviruset hänger ofta kvar i inomhusluften – forskare uppmanar oss att vrida upp luftkonditioneringen och att använda luftrenare. Svenska YLE. 28.1.2022. https://svenska.yle.fi/a/7-10012085
Läkare med postcovid: Jag saknar den jag var. Detta är min berättelse om postcovid och den är varken unik eller allmängiltig, skriver läkaren Lisa Norén som har postcovid och är aktiv i nätverket Läkare till läkare. Hon tar upp Hanne Kjöllers uppmärksammade artiklar om postcovid och avfärdar att det är en kultursjukdom. Hon menar att sjukdomen är komplex och därför krävs det läkare med postcovidkompetens. Kvartal. 27.1.2022. https://kvartal.se/artiklar/lakare-med-postcovid-jag-saknar-den-jag-var/
Asiantuntijan mukaan olemme koronapandemian loppuvaiheilla, mutta sinänsä korona ei koskaan lopu. Koronapandemia päättyy eri paikoissa eri aikaan, mutta epidemiologi Jussi Sanen mukaan pandemiassa ollaan jo loppuvaiheilla. HUSin apulaisylilääkäri Eeva Ruotsalainen ei kuitenkaan halua olla ylioptimistinen.YLE-Uutiset. 27.1.2022. https://yle.fi/uutiset/3-12288922?
COVID-19 vaccine surveillance report. Week 4. UK Health Security Agency. 27.1.2022. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1050721/Vaccine-surveillance-report-week-4.pdf
Turkulainen hammastahna-suuvesi covid-19-infektiota vastaan sai patentin Yhdysvalloissa.
Yhtiön mukaan koronaa vastaan toimiva hammastahna-suuvesi perustuu elimistön oman kemiallisen puolustusmekanismin vahvistamiseen. Mediuutiset. 27.1.2022. https://www.mediuutiset.fi/uutiset/mu/8f2511e1-86f7-499e-8195-d9c95ea05583?
The Covid Resilience Ranking. The Best and Worst Places to Be as We Learn to Live With Covid. Bloomberg. 27.1.2022. https://www.bloomberg.com/graphics/covid-resilience-ranking/?
Implication of COVID-19 on Erythrocytes Functionality: Red Blood Cell Biochemical Implications and Morpho-Functional Aspects. Int J Mol Sci. 27.1.2022. https://www.mdpi.com/1422-0067/23/4/2171/htm
A second version of omicron is spreading. Here’s why scientists are on alert. NPR. 27.1.2022. https://www.npr.org/sections/goatsandsoda/2022/01/27/1076123109/new-covid-variant-omicron-ba-2
Satasairaalan henkilöstöllä todettu runsaasti koronatartuntoja – Leikkauksia joudutaan perumaan. Kiireelliset toimenpiteet ja päivystysleikkaukset toteutetaan poikkeustilanteesta huolimatta normaalisti. Satakunnan Kansa. 26.1.2022. https://www.satakunnankansa.fi/koronainfo/art-2000008569067.html
Neutralizing immunity in vaccine breakthrough infections from the SARS-CoV-2 Omicron and Delta 2 variants. medRxiv. 26.1.2022. https://www.medrxiv.org/content/10.1101/2022.01.25.22269794v1.full.pdf
When will the COVID-19 pandemic end? 4 essential reads on past pandemics and what the future could bring. The Conversation. 26.1.2022. https://theconversation.com/when-will-the-covid-19-pandemic-end-4-essential-reads-on-past-pandemics-and-what-the-future-could-bring-175587?
The Real-time Assessment of Community Transmission (REACT) programme is one of the largest, most significant pieces of research looking at how the COVID-19 pandemic is progressing in England. Imperial College. 25.1.2022. https://www.imperial.ac.uk/medicine/research-and-impact/groups/react-study/real-time-assessment-of-community-transmission-findings/
The study is being carried out by a world-class team of scientists, clinicians and researchers at Imperial College London, in partnership with Ipsos MORI, and was commissioned by the Department of Health and Social Care. Explore our study’s findings below.
Neutralizing immunity in vaccine breakthrough infections from the SARS-CoV-2 Omicron and Delta variants. medRxiv. 25.1.2022. https://www.medrxiv.org/content/10.1101/2022.01.25.22269794v1.full.pdf
Close relatives of MERS-CoV in bats use ACE2 as their functional receptors, bioRxiv.25.1.2022. https://www.biorxiv.org/content/10.1101/2022.01.24.477490v1.full.pdf
COVID-19: endemic doesn’t mean harmless. Nature. 24.1.2022. https://www.nature.com/articles/d41586-022-00155-x
Rosy assumptions endanger public health — policymakers must act now to shape the years to come.
Parties may lead to his downfall, but is this the worst of what Johnson has done? BMJ. 24.1.2022. https://www.bmj.com/content/376/bmj.o196?
Disease severity during SARS-COV-2 reinfection: a nationwide study. J of Infection. 24.1.2022. https://www.journalofinfection.com/article/S0163-4453(22)00010-X/fulltext
COVID-19: endemic doesn’t mean harmless. Rosy assumptions endanger public health — policymakers must act now to shape the years to come. Nature. 24.1.2022. https://www.nature.com/articles/d41586-022-00155-x
Functional evaluation of the P681H mutation on the proteolytic activation of the SARS-CoV-2 variant B.1.1.7 (Alpha) spike. iScience. 21.1.2022. https://www.sciencedirect.com/science/article/pii/S2589004221015595?
“Hengitysilma paremmaksi ja FFP2-maskit kasvoille” – fysiikka ei erehdy, koronan torjunnassa on otettava uusi askel. Pandemian alkuvaiheessa monet asiantuntijat ja poliitikot uskoivat vahvasti myyttiin, etteivät virukset leviä ensisijaisesti hengitysilmassa vaan kosketustartunnan kautta. Fyysikot toivat kuitenkin jo pandemian alkuvaiheessa esille, että korona leviää voimakkaimmin nimenomaan hengitysilmassa. Virusta täytyykin jatkossa torjua rokotusten ohella ennen kaikkea hengitysilman laatuun keskittymällä, kirjoittaa apulaisprofessori Ville Vuorinen. MustRead. 21.1.2022. https://www.mustread.fi/artikkelit/hengitysilma-paremmaksi-ja-ffp2-maskit-kasvoille-fysiikka-ei-erehdy-koronan-torjunnassa-on-otettava-uusi-askel/?
January 21 – 31
Rapid vigilance and episodic memory decrements in COVID-19 survivors. Brain Communications. 19.1.2022. https://academic.oup.com/braincomms/article/4/1/fcab295/6511053?login=false
Ilmanvaihto-ohjeistus varhaiskasvatuksen, opetuksen ja koulutuksen tilojen käytöstä vastaaville. THL. 19.1.2021. https://thl.fi/fi/web/ymparistoterveys/sisailma/koronavirus-ja-sisailman-turvallisuus/ilmanvaihto-ohjeistus-varhaiskasvatuksen-opetuksen-ja-koulutuksen-tilojen-kaytosta-vastaaville
Differences in environmental stability among SARS-CoV-2 variants of concern: Omicron has higher stability. bioRxiv. 19.1.2022. https://www.biorxiv.org/content/10.1101/2022.01.18.476607v1.full
SARS-CoV-2 breakthrough infections elicit potent, broad, and durable neutralizing antibody responses. Cell. 19.1.2022. https://www.cell.com/cell/fulltext/S0092-8674(22)00069-1#relatedArticles
Biden Will Give Away Free N95 Masks at Pharmacies and Health Centers. TIME. 19.1.2022. https://time.com/6140223/biden-free-n95-masks/?utm_medium=email&utm_source=sfmc&utm_campaign=newsletter+coronavirus+default+ac&utm_content=+++20220119+++body&et_rid=149179605&lctg=149179605
Respiratory viruses that hijack immune mechanisms may have Achilles’ heel. Phys.org. 18.1.2022. https://phys.org/news/2022-01-respiratory-viruses-hijack-immune-mechanisms.html
Incidence of Type 1 Diabetes in Children and Adolescents During the COVID-19 Pandemic in Germany: Results From the DPV Registry. Diabetes Care. 17.1.2022. https://diabetesjournals.org/care/article-abstract/doi/10.2337/dc21-0969/139385/Incidence-of-Type-1-Diabetes-in-Children-and?redirectedFrom=fulltext
Israel Finds Fourth COVID Booster is only ‘Partially Effective,’ Vast Majority of Hospitalised Omicron Patients Are Unvaccinated. Health Policy Watch. 17.1.2022. https://healthpolicy-watch.news/israel-fourth-covid-booster-ineffective/
Tamperelaisyritys sai luvan koronakeksinnölleen: puhallustesteri antaa alle minuutissa tiedon koronatartunnasta. Suomessa kehitetty puhallustesteri mittaa uloshengityksestä koronainfektion aiheuttamia yhdisteitä. YLE-Uutiset. 17.1.2022. https://yle.fi/uutiset/3-12273307?
Kannanotto: Valmiuslaki ei takaa terveydenhuollon kantokykyä. Nuorten Lääkärien Yhdistys. 17.1.2022. https://www.nly.fi/kannanotto-valmiuslaki-ei-takaa-terveydenhuollon-kantokykya/
Hengityssuojaimet toimivat, vaikka jotkut muuta väittävätkin [Ari Laaksonen]. Kaleva. 16.1.2022. https://www.kaleva.fi/hengityssuojaimet-toimivat-vaikka-jotkut-muuta-vai/4249701
Excess mortality in 2020-2021 % change compared with 2016-2019 average. Eurostat Statistics explained. nn.1.2022. https://ec.europa.eu/eurostat/statistics-explained/index.php?title=File:Excess_Mortality_Update_DEC2021GIF.gif
Risk factors and disease profile of post-vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: a prospective, community-based, nested, case-control study. Lancet Infectious Diseases. NN.1.2022. https://www.sciencedirect.com/science/article/pii/S1473309921004606
With COVID-19, Air Is Both the Problem and the Solution. SARS-CoV-2 can linger in the air. Dealing with it can be relatively easy, but first, we have to admit we have a problem McGill. 15.1.2022. https://www.mcgill.ca/oss/article/covid-19/covid-19-air-both-problem-and-solution
One in nine recent virus cases in Israel are reinfections — report. High proportion of those who recovered and were then reinfected were at least partially vaccinated; officials believe confirmed daily cases will reach 100,000 in coming days. Times of Israel. 15.1.2022. https://www.timesofisrael.com/one-in-nine-recent-virus-cases-in-israel-are-reinfections-report/
Risk for Newly Diagnosed Diabetes >30 Days After SARS-CoV-2 Infection Among Persons Aged <18 Years — United States, March 1, 2020–June 28, 2021. CDC. 14.1.2022. https://www.cdc.gov/mmwr/volumes/71/wr/mm7102e2.htm
Weekly epidemiological update: Omicron variant of concern (VOC) – week 2 (data as of 13 January 2022) EU/EEA. ECDC. 14.1.2022. https://www.ecdc.europa.eu/en/news-events/weekly-epidemiological-update-omicron-variant-concern-voc-week-2-data-13-january-2022
COVID-19 starkly increases pregnancy complications, including stillbirths, among the unvaccinated, Scottish study shows. Separate study finds timing of infection during pregnancy predicts prematurity. Science. 14.1.2022. https://www.science.org/content/article/covid-19-starkly-increases-pregnancy-complications-including-stillbirths-among?
Covid-19: Peak of viral shedding is later with omicron variant, Japanese data suggest. BMJ. 13.1.2022. https://www.bmj.com/content/376/bmj.o89
Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection. Nature Immunology. 13.1.2022. https://www.nature.com/articles/s41590-021-01113-x?
Comparison of serum neurodegenerative biomarkers among hospitalized COVID-19 patients versus non-COVID subjects with normal cognition, mild cognitive impairment, or Alzheimer’s dementia. Alzheimer’s Association. 13.1.2022. https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.12556
Covid-19: Peak of viral shedding is later with omicron variant, Japanese data suggest. BMJ. 13.1.2022. https://www.bmj.com/content/376/bmj.o89
Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection. Nature Immunology. 13.1.2022. https://www.nature.com/articles/s41590-021-01113-x
The effectiveness of vaccination against long COVID. A rapid evidence briefing. UK Health Security Agency. 12.1.2022. https://ukhsa.koha-ptfs.co.uk/cgi-bin/koha/opac-retrieve-file.pl?id=fe4f10cd3cd509fe045ad4f72ae0dfff
Covid-19 control measures and common paediatric infections. BMJ. 12.1.2022. https://doi.org/10.1136/bmj.n3093
Analyzing natural herd immunity media discourse in the United Kingdom and the United States. [Great Barrington Declaration, False balance in media coverage]. PLOS Global Public Health. 12.1.2022. https://journals.plos.org/globalpublichealth/article?id=10.1371/journal.pgph.0000078
Indirect effects of the covid-19 pandemic on childhood infection in England: population based observational study. BMJ. 12.1.2022. https://doi.org/10.1136/bmj-2021-067519
The Dynamics of SARS-CoV-2 Infectivity with Changes in Aerosol. Microenvironment. medRxiv. 10.1.2022. https://www.medrxiv.org/content/10.1101/2022.01.08.22268944v1.full.pdf
Covid loses 90% of ability to infect within 20 minutes in air – study
Exclusive: Findings highlight importance of short-range Covid transmission. The Guardian. 11.1.2022. https://www.theguardian.com/world/2022/jan/11/covid-loses-90-of-ability-to-infect-within-five-minutes-in-air-study
WHO: Jatkuvissa tehosterokotuksissa ei järkeä
Maailman terveysjärjestön mukaan tarvitaan rokote, joka ehkäisee tartuntoja. Iltalehti. 11.1.2022. https://www.iltalehti.fi/ulkomaat/a/5ca307c8-7c15-4476-a361-b544d3b9e77e?
January 11 – 20
The Dynamics of SARS-CoV-2 Infectivity with Changes in Aerosol Microenvironment. medRxiv. 10.1.2022. https://www.medrxiv.org/content/10.1101/2022.01.08.22268944v1
Infectious viral load in unvaccinated and vaccinated patients infected with SARS-CoV-2 WT, Delta and Omicron. MedRxiv. 10.1.2022. https://www.medrxiv.org/content/10.1101/2022.01.10.22269010v1
Liikuntaväki huolissaan lasten harrastusten rajoituksista – THL:n Tervahauta: Hyödyt vähäiset, haitat suuret. Viranomaisten toimia pidetään poukkoilevana ja rajoituskaavailuja epäreiluina lasten ja nuorten kannalta. Lajiliittojen johtajat pelkäävät koko ikäluokan menettämistä. YLE-Uutiset. 8.1.2022. https://yle.fi/uutiset/3-12263002?
Mild respiratory SARS-CoV-2 infection can cause multi-lineage cellular dysregulation and myelin loss in the brain. bioRxiv. 10.1.2022. https://www.biorxiv.org/content/10.1101/2022.01.07.475453v1.full
Hospitals Are in Serious Trouble. Omicron is inundating a health-care system that was already buckling under the cumulative toll of every previous surge. Atlantic. 7.1.2022. https://www.theatlantic.com/health/archive/2022/01/omicron-mild-hospital-strain-health-care-workers/621193/
STM:n asiantuntijaryhmä: Korona voi ilmetä pitkäkestoisena joka toisella aikuisella – HS seurasi tiedotustilaisuutta. Uupumus, hengenahdistus ja kognitiiviset häiriöt yleisiä oireita. Helsingin Sanomat. 7.1.2022. https://www.hs.fi/kotimaa/art-2000008523531.html
Immunity against Omicron from breakthrough infection could be a matter of timing. Laboratory studies hint that a longer interval between vaccination and infection is better than a shorter one. Nature. 7.1.2022. https://www.nature.com/articles/d41586-022-00004-x?
Risk Factors for Severe COVID-19 Outcomes Among Persons Aged ≥18 Years Who Completed a Primary COVID-19 Vaccination Series — 465 Health Care Facilities, United States, December 2020–October 2021. CDC Morbidity and Mortality Weekly Report. 7.1.2022. https://www.cdc.gov/mmwr/volumes/71/wr/mm7101a4.htm
How to Think About Covid Data Right Now. New York Times. 7.1.2022. https://www.nytimes.com/interactive/2022/01/07/us/covid-data-explained.html
Higher viral load and infectivity increase risk of aerosol transmission for Delta and Omicron variants of SARS-CoV-2. Swiss Medical Weekly. 6.1.2021. https://smw.ch/article/doi/smw.2022.w30133
Virologian professori: Maskien käyttö on nyt tärkeämpää kuin koskaan – Tilanne pääkaupunkiseudulla ”kuin Lontoossa”. Uusi Suomi. 6.1.2022. https://www.uusisuomi.fi/uutiset/virologian-professori-maskien-kaytto-on-nyt-tarkeampaa-kuin-koskaan-tilanne-paakaupunkiseudulla-kuin-lontoossa/488a3898-2b85-4b5a-ab09-edb16d5ad59f
Comprehensive Chemosensory Psychophysical Evaluation of Self-reported Gustatory Dysfunction in Patients With Long-term COVID-19. A Cross-sectional Study. JAMA Network. 6.1.2022. https://jamanetwork.com/journals/jamaotolaryngology/fullarticle/2787787?
A National Strategy for the “New Normal” of Life With COVID. JAMA Network. 6.1.2022. https://jamanetwork.com/journals/jama/article-abstract/2787944
Gut microbiota dynamics in a prospective cohort of patients with post-acute COVID-19 syndrome. BMJ / Gut. 5.1.2022. https://gut.bmj.com/content/early/2022/01/05/gutjnl-2021-325989
South African scientist thinks she may have solved the mystery of long COVID-19, which afflicts 100M people. A recent study by Resia Pretorius and her team at Stellenbosch University in South Africa suggests that long COVID-19 may be triggered by microclots. The Hill. 5.1.2022. https://thehill.com/changing-america/well-being/medical-advances/588443-south-african-scientist-thinks-she-may-have
Association between vaccination status and reported incidence of post-acute COVID-19 symptoms in Israel: a cross-sectional study of patients tested between March 2020 and November 2021. medRxiv. 5.1.2022. https://www.medrxiv.org/content/10.1101/2022.01.05.22268800v2
Practical Indicators for Risk of Airborne Transmission in Shared Indoor Environments and Their Application to COVID-19 Outbreaks. Environmental Science & Technology. 5.1.2022. https://doi.org/10.1021/acs.est.1c06531
Residual SARS-CoV-2 viral antigens detected in GI and hepatic tissues from five recovered patients with COVID-19. @IanRicksecker, A Duke pathology study in Singapore “detected SARS-CoV-2 .. in the colon, appendix, ileum, haemorrhoid, liver, gallbladder and lymph nodes .. suggesting widespread multiorgan involvement of the viral infection.” The same study found “evidence of residual virus in .. tissues during the convalescent phase, up to 6 months after recovery, in a non-postmortem setting,” suggesting that “a negative swab result might not necessarily indicate complete viral clearance from the body.” Gut. 5.1.2022. gut.bmj/content/gutjnl-2021-324280.full.pdf
Discordant SARS-CoV-2 PCR and Rapid Antigen Test Results. When Infectious: A December 2021 Occupational Case Series. medRxiv. 5.1.2022. Discordant SARS-CoV-2 PCR and Rapid Antigen Test Results When Infectious: A December 2021 Occupational Case Series (medrxiv.org)
By wearing face masks in schools, students protect their learning, families and long-term health. Flawed or unrepresentative studies promote the view that masks are ineffective or harmful. But at times when Covid case rates are high, they’re one of our best options. iNews. 5.1.2022. https://inews.co.uk/opinion/by-wearing-face-masks-in-schools-students-protect-their-learning-families-and-long-term-health-1381627
Practical Indicators for Risk of Airborne Transmission in Shared Indoor Environments and Their Application to COVID-19 Outbreaks. Environ Sci Technol. 5.1.2022. https://pubs.acs.org/doi/10.1021/acs.est.1c06531
Early Israeli findings show fivefold boost from fourth COVID vaccine dose. CIDRAP, University of Minnesota. 4.1.2022. https://www.cidrap.umn.edu/news-perspective/2022/01/early-israeli-findings-show-fivefold-boost-fourth-covid-vaccine-dose
Viikoittaiset tilastot kuolleista julkaistaan jatkossa kerran kuukaudessa. Tilastokeskus. 4.1.2022. https://www.stat.fi/uutinen/viikoittaiset-tilastot-kuolleista-julkaistaan-jatkossa-kerran-kuukaudessa
Long Covid: why do some people have symptoms months after infection? Researchers say more than 100m suffer ill effects for at least 12 weeks. Financial Times. 4.1.2022. https://www.ft.com/content/ed89cad2-6f82-44f0-b01d-c4490e4a7372?shareType=nongift
A framework for reconstructing SARS-CoV-2 transmission dynamics using excess mortality data. (Iran) medRxiv. 4.1.2022. https://www.medrxiv.org/content/10.1101/2021.10.04.21264540v2.full.pdf
Mapping the antigenic diversification of SARS-CoV-2. medRxiv. 3.1.2022. https://www.medrxiv.org/content/10.1101/2022.01.03.21268582v1
Covid-19: An urgent call for global “vaccines-plus” action. BMJ. 3.1.2022. https://www.bmj.com/content/376/bmj.o1
Superspreading: Insufficient ventilation led to a probable long-range airborne transmission of SARS-CoV-2 on two buses. Buiding and Environment. NN.1.2022. https://www.sciencedirect.com/science/article/pii/S0360132321008118?via%3Dihub
The hyper-transmissible SARS-CoV-2 Omicron variant exhibits significant antigenic change, vaccine escape and a switch in cell entry mechanism. @IanRicksecker, Luckily, the University of Glasgow found that “Whilst Delta is optimised for fusion at the cell surface, Omicron .. achieves entry through endosomal fusion. This switch .. offers [an] explanation for [its] reduced syncytia formation.”1.1.2022. https://t.co/lsAwufl6dl
What is an N95 respirator? N95DECON Publications. 2022. https://www.n95decon.org/publications
2022 January 1 – 10
Studies suggest why omicron is less severe: It spares the lungs. The Seattle Times. 31.12.2021. https://www.seattletimes.com/nation-world/studies-suggest-why-omicron-is-less-severe-it-spares-the-lungs/
Travelers infected one another across hallway in Covid-19 quarantine facility, New Zealand research shows. CNN Travel. 31.12.2021. https://edition.cnn.com/2021/12/30/health/new-zealand-covid-facility-transmission/index.html
Paradoxical sex-specific patterns of autoantibody response to SARS-CoV-2 infection. @IanRicksecker, Those warnings have since been proven by discovery of autoimmune features. This study of 177 Los Angeles healthcare workers found that all had persistent self-attacking antibodies at least 6 months after infection, regardless of illness severity. J Translational Medicine. 30.12.2021. https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-021-03184-8
Covid-19: Is it safe to reduce the self-isolation period? BMJ. 30.12.2021. https://www.bmj.com/content/375/bmj.n3164?
Taiwan rejects US CDC guidance on 5-day quarantine. Some Omicron cases still infectious up to 12 days after testing positive. Taiwan News. 30.12.2021. https://www.taiwannews.com.tw/en/news/4393548
Rekord bei Corona-Neuinfektionen. Die Pandemie erreicht in der Schweiz und weltweit einen neuen Höhepunkt. Mehr als 17’600 Ansteckungen innert 24 Stunden – und das dürfte erst der Anfang einer riesigen Welle in der Schweiz sein. Welche Länder ebenfalls stark betroffen sind. BaZ. 29.12.2021. https://www.bazonline.ch/die-pandemie-erreicht-in-der-schweiz-und-weltweit-einen-neuen-hoehepunkt-318445720632?
The SARS-CoV-2 B.1.1.529 Omicron virus causes attenuated infection and disease in mice and hamsters. Research Square. 29.12.2021. https://www.researchsquare.com/article/rs-1211792/v1
Omikron voi todella olla lievempi – Tutkija: Ihan huippua. Akatemiatutkijan mukaan uusi virusmuunnos ei ilmeisesti pääse leviämään yhtä tuhoisasti keuhkoissa kuin aiempi delta. Verkkouutiset. 29.12.2021. https://www.verkkouutiset.fi/omikron-voi-todella-olla-lievempi-tutkija-ihan-huippua/#773fc543
HUSin ylilääkäri ehdottaa erillisten koronasairaaloiden perustamista Suomeen. Ylilääkäri Eero Hirvensalon mukaan sairaalat olisi mahdollista perustaa terveydenhuollon niukoista resursseista huolimatta, jos mukana olisi useita toimijoita ja soveltuvilta osin yksityinen terveydenhuolto. YLE Uutiset. 29.12.2021. https://yle.fi/uutiset/3-12248864?
Can COVID-19 alter your personality? Here’s what brain research shows. Alzheimer’s, Parkinson’s, and traumatic brain injury can cause changes in behavior by altering brain anatomy. Now it seems the coronavirus can too. National Geographic. 29.12.2021. https://www.nationalgeographic.com/science/article/can-covid-19-alter-your-personality-heres-what-brain-research-shows?cmpid=org=ngp::mc=social::src=twitter::cmp=editorial::add=tw20211229science-sciencecovidpersonalitydisorder&linkId=146317189
CDC shortens recommended Covid-19 isolation and quarantine time. CNN Health. 28.12.2021. https://edition.cnn.com/2021/12/27/health/cdc-covid-quarantine-isolation-shortened-recommendation/index.html?
Intranasal inhibitor blocks omicron and other variants of SARS-CoV-2. Research Square. 28.12.2021. https://www.researchsquare.com/article/rs-1196079/v1
Combined triple treatment of fibrin amyloid microclots and platelet pathology in individuals with Long COVID/ Post-Acute Sequelae of COVID-19 (PASC) can resolve their persistent symptoms. @IanRicksecker, [COVID-19] also causes microclots: “Fibrin(ogen) amyloid microclots and platelet hyperactivation [were] observed in [Long COVID] patients,” in this work by Stellenbosch University of South Africa, which also explored potential treatments. Research Square. 28.12.2021. https://www.researchsquare.com/article/rs-1205453/v1
Risk of Cardiovascular Events after Covid-19: a double-cohort study. (@IanRicksecker) Oregon Health & Science University found that “symptomatic or asymptomatic SARS-CoV-2 infection is associated with increased risk of [fatal] cardiovascular outcomes and has causal effect on all-cause mortality.” medRxiv. 27.12.2021. https://doi.org/10.1101/2021.12.27.21268448
Omicron infection enhances neutralizing immunity against the Delta variant. medRxiv. 27.12.2021. https://www.medrxiv.org/content/10.1101/2021.12.27.21268439v1.full
Emeritusprofessori: Visiiri suojaa koronalta kuin aurinkolasit HIV:lta. Verkkouutiset. 27.12.2021. https://www.verkkouutiset.fi/emeritusprofessori-visiiri-suojaa-koronalta-yhta-hyvin-kuin-aurinkolasit-hivlta/#773fc543
Characterizing Long COVID in an International Cohort: 7 Months of Symptoms and Their Impact. medRxiv. 27.12.2021. https://www.medrxiv.org/content/10.1101/2020.12.24.20248802v2
Coronavirus Can Persist for Months After Traversing Body. BloombergQuint. 26.12.2021. https://www.bloombergquint.com/coronavirus-outbreak/coronavirus-can-persist-for-months-after-traversing-entire-body.
The omicron (B.1.1.529) SARS-CoV-2 variant of concern does not readily infect Syrian hamsters. bioRxiv. 26.12.2021. https://www.biorxiv.org/content/10.1101/2021.12.24.474086v1
Aerosol generation during general anesthesia is comparable to coughing: An observational clinical study. Acta Anesthesiologica Scandinavica. 24.12.2021. https://onlinelibrary.wiley.com/doi/10.1111/aas.1402
SARS-CoV-2 variants of concern and variants under investigation in England. Technical briefing 33. UK Health Security Agency. 23.12.2021. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1043807/technical-briefing-33.pdf
Covid-19: Early studies give hope omicron is milder than other variants. BMJ. 23.12.2021. https://www.bmj.com/content/375/bmj.n3144?
Helsinki GSE:n Tilannehuoneen selvitys: Rokotukset suojaavat lapsia tehokkaasti tartunnoilta – 11-vuotiailla jopa kaksinkertainen määrä tartuntoja 12-vuotiaisiin verrattuna. Helsinki Graduate School of Economics. 23.12.2021. https://www.helsinkigse.fi/corona/helsinki-gsen-tilannehuoneen-selvitys-rokotukset-suojaavat-lapsia-tehokkaasti-tartunnoilta-11-vuotiailla-jopa-kaksinkertainen-maara-tartuntoja-12-vuotiaisiin-verrattuna/
Coronavirus disease (COVID-19): How is it transmitted? How does COVID-19 spread between people? WHO. 23.12.2021. https://www.who.int/news-room/questions-and-answers/item/coronavirus-disease-covid-19-how-is-it-transmitted
Medical technologies have been central to US pandemic response – but social behaviors matter just as much. The Conversation. 22.12.2021. https://theconversation.com/medical-technologies-have-been-central-to-us-pandemic-response-but-social-behaviors-matter-just-as-much-171587?
Kannattaako oireettoman tehdä kotitesti? Pitääkö lapset testata ennen isovanhempien tapaamista? 10 kysymystä ja vastausta toisesta koronajoulusta. Turun yliopiston virusopin professori Ilkka Julkusen mukaan kotitestejä voi hyvin käyttää lieväoireisessa taudissa. Kotitestistä saatuun negatiiviseen tulokseen pitää kuitenkin suhtautua pienellä varauksella. Helsingin Sanomat. 22.12.2021. https://www.hs.fi/hyvinvointi/art-2000008492207.html
How The Koch Network Hijacked The War On Covid [GBD, Trump]. CMD. 22.12.2021. https://www.exposedbycmd.org/2021/12/22/how-the-koch-network-hijacked-the-war-on-covid/
What now for Sweden and covid-19? BMJ. 22.12.2021. https://www.bmj.com/content/375/bmj.n3081?
Covid News: What the U.S. Vaccination Campaign Looks Like One Year On. Pfizer said a combination of pills reduced the risk of hospitalization and death by 89 percent if given within three days of the onset of symptoms. New York Times. 21.12.2021. https://www.nytimes.com/live/2021/12/14/world/covid-omicron-vaccines#pfizer-covid-pill-paxlovid
In world first, Israel set to give 4th COVID shot to over 60s, at-risk groups. Hailing recommendation by panel of health experts, Bennett orders swift roll-out of extra vaccine booster for people over 60, immunocompromised and health care workers. The Times of Israel. 21.12.2021. https://www.timesofisrael.com/health-ministry-panel-recommends-fourth-covid-shot-for-at-risk-groups/?
Viranomainen määräsi yleisötilaisuudet säppiin – Kirkko vetää omaa linjaa: joulukirkot järjestetään. ”Älytön päätös tässä vaiheessa.” Salon seurakunnassa kritisoidaan tuomiokapitulin ohjetta. Kirkon mukaan uskonnon harjoittaminen auttaa ihmisiä jaksamaan pandemiassa. Suomen Kuvalehti. 21.12.2021. https://suomenkuvalehti.fi/jutut/kotimaa/viranomainen-maarasi-yleisotilaisuudet-sappiin-kirkko-vetaa-omaa-linjaa-joulukirkot-jarjestetaan/?
Koronarajoitukset kiristymässä. Useat alueet ovat tiedottaneet rajoitussuosituksista. Lääkärilehti. 21.12.2021. https://www.laakarilehti.fi/ajassa/ajankohtaista/koronarajoitukset-kiristymassa/?public
December 21 – 31
Avoin kirje päättäjille: Omikronin torjunta vaatii kiireellisiä rajoitustoimia. Eroonkoronasta. 20.12.2021. https://www.eroonkoronasta.fi/avoin-kirje-paeaettaejille-omikronin-torjunta-vaatii-kiireellisiae-rajoitustoimia/#s_allekirjoittajat
SARS-CoV-2 infection and persistence throughout the human body and brain. Research Square. 20.12.2021. https://assets.researchsquare.com/files/rs-1139035/v1_covered.pdf?c=1640020576
Teholla 63 koronapotilasta – tehohoidon koordinaattorit: Hallituksen tehtävä rajuja päätöksiä ja heti. Professori Matti Reinikainen arvioi, että Suomeen vasta tuloaan tekevä omikron työllistää sairaaloita arvioitua enemmän. Etelä-Afrikassa virus on jyllännyt nuorten keskuudessa. YLE-Uutiset. 20.12.2021. https://yle.fi/uutiset/3-12239558?
Multisystem Inflammatory Syndrome in Children by COVID-19 Vaccination Status of Adolescents in France. JAMA Network. 20.12.2021. https://jamanetwork.com/journals/jama/fullarticle/2787495
Multifactorial seroprofiling dissects the contribution of pre-existing human coronaviruses responses to SARS-CoV-2 immunity. nature. 18.12.2021. https://www.nature.com/articles/s41467-021-27040-x
Ministeri Krista Kiuru: Hätäjarrusta on päätettävä jo ensi viikolla ja rajoitustoimia on lisättävä merkittävästi. Kiuru toivoo, että Italian tapaan Suomi alkaa vaatia myös eurooppalaisilta ennen maahan tuloa otettua koronatestitodistusta. Helsingin Sanomat. 18.12.2021. https://www.hs.fi/politiikka/art-2000008474448.html
Status på omikron-varianten (B.1.1.529) pr. Statens Serum Institut finder et stadigt stigende antal omikron tilfælde i Danmark. Samlet er der nu fundet 11.559 tilfælde af smitte med virus-varianten omikron. Alle fakta om forekomsten af omikron i Danmark udsendes nu i en daglig rapport. Statens SerumInstitut. 17.12.2021. https://www.ssi.dk/aktuelt/nyheder/2021/status-pa-omikron-varianten-b11529-pr-171221
Omicron largely evades immunity from past infection or two vaccine doses. Imperial College. 17.12.2021. https://www.imperial.ac.uk/news/232698/omicron-largely-evades-immunity-from-past/
How Omicron Evades Natural Immunity, Vaccination, And Monoclonal Antibody Treatments. Forbes. 17.12.2021. https://www.forbes.com/sites/williamhaseltine/2021/12/17/how-omicron-evades-natural-immunity-vaccination-and-monoclonal-antibody-treatments/?sh=d4e595f60e08
CDC recommends Pfizer, Moderna vaccines over J&J’s. CNN Health. 17.12.2021. https://edition.cnn.com/2021/12/16/health/johnson-vaccine-acip-recommendation-mrna-preferred/index.html
Vaccine inequality may undermine the booster programme. BMJ. 17.12.2021. https://www.bmj.com/content/375/bmj.n3118
Huonossa sisäilmassa koronatartunnan voi saada minuuteissa – tehokas tuuletus laskee riskiä luultua enemmän, kertoo VTT:n tuore tutkimus. Mitä enemmän huonetilassa on viruksia, sitä suurempi on riski taudin leviämisestä. Tuulettamalla viruspitoisuudet tippuvat tutkijoiden mukaan jopa 90 prosenttia. YLE-Uutiset. 16.12.2021. https://yle.fi/uutiset/3-12231997?
Report 48 – The value of vaccine booster doses to mitigate the global impact of the Omicron SARS-CoV-2 variant. Imperial College. 16.12.2021. https://www.imperial.ac.uk/mrc-global-infectious-disease-analysis/covid-19/report-48-global-omicron/
The S1 protein of SARS-CoV-2 crosses the blood-brain barrier in mice. @IanRicksecker The virus appears to be able to cross the blood-brain barrier and cause significant neurological damage. The ability of the spike protein to cross the blood-brain barrier was demonstrated in mice at the University of Washington. Nature Neuroscience. 16.12.2021. https://doi:10.1038/s41593-020-00771-8.
Report 49 – Growth, population distribution and immune escape of Omicron in England. Imperial College. 16.12.2021. https://www.imperial.ac.uk/mrc-global-infectious-disease-analysis/covid-19/report-49-Omicron/
Missed shots: Science revisits its 2020 Breakthrough of the Year. The COVID-19 vaccine rollout was a spectacular success—and a stunning tragedy. Science . 16.12.2021. https://www.science.org/content/article/missed-shots-science-revisits-its-2020-breakthrough-year?
A tantalizing clue to why omicron is spreading so quickly. NPR. 15.12.2021. https://www.npr.org/sections/goatsandsoda/2021/12/15/1064597592/a-tantalizing-clue-to-why-omicron-is-spreading-so-quickly
HKUMed finds Omicron SARS-CoV-2 can infect faster and better than Delta in human bronchus but with less severe infection in lung. HKU Faculty of Medicine News. 15.12.2021. https://www.med.hku.hk/en/news/press/20211215-omicron-sars-cov-2-infection
Covid-19: Long covid symptoms among hospital inpatients show little improvement after a year, data suggest. BMJ. 15.12.2021. https://www.bmj.com/content/375/bmj.n3092?=&utm_source=adestra&utm_medium=email&utm_campaign=usage&utm_content=daily&utm_term=text
U.S. study suggests vaccines may be ineffective against Omicron without booster. Reuters. 15.12.2021. https://www.reuters.com/business/healthcare-pharmaceuticals/us-study-suggests-covid-19-vaccines-may-be-ineffective-against-omicron-without-2021-12-14/?
Assessment of the further emergence of the SARS-CoV-2 Omicron VOC in the context of the ongoing Delta VOC transmission in the EU/EEA, 18th update. ECDC. 15.12.2021. https://www.ecdc.europa.eu/en/publications-data/covid-19-assessment-further-emergence-omicron-18th-risk-assessment
Pohjois-Pohjanmaalla tahallista koronalle altistumista: ”Liittyy luultavasti koronapassiin”. Kallion kuntayhtymä kertoo huolestuttavasta koronailmiöstä. Iltalehti. 15.12.2021. https://www.iltalehti.fi/koronavirus/a/8ec31170-683e-470c-a3db-091fbc205f23?
THL haluaa rajoille kireämmän linjan kuin hallitus suunnittelee – Ruotsikin on omikronin riskimaa. Valtioneuvosto on päättämässä huomenna torstaina matkustusrajoitusten kiristämisestä. Sisäministeri Mikkonen sanoo, että hallituksessa on keskusteltu myös sisärajatarkastusten palauttamisesta. YLE-Uutiset. 15.12.2021. https://yle.fi/uutiset/3-12231096
REVIEW: How Common is Long COVID in Children and Adolescents? Pediat Incfext Dis J. NN.12.2021. https://journals.lww.com/pidj/fulltext/2021/12000/how_common_is_long_covid_in_children_and.20.aspx
Evidence for a mouse origin of the SARS-CoV-2 Omicron variant. Journal of Genetics and Genomics. nn.12.2021. https://www.sciencedirect.com/science/article/pii/S1673852721003738
Final data on pills to treat Covid-19 holds strong against hospitalization and death, Pfizer says. CNN Health. 14.12.2021. https://edition.cnn.com/2021/12/14/health/pfizer-paxlovid-pills-covid-treatment/index.html?
Pfizer’s Covid Pill Works Well, Company Confirms in Final Analysis. The treatment, called Paxlovid, is likely to work against Omicron and could be available in the United States before the end of the year. New York Times. 14.12.2021. https://www.nytimes.com/2021/12/14/health/pfizer-covid-19-pill-paxlovid.html?
Sairaalapomot eivät näe hätäjarrulle tarvetta hoidon kuormituksen takia – johtajalääkäri: ”vaikuttavin toimi olisi puuttuminen ravintoloiden aukioloihin”
Koronan omikronmuunnoksen tulevaa vaikutusta sairaaloiden kuormitukseen ei vielä tiedetä. Sosiaali- ja terveysministeriö valmistautuu rajoitusten tiukentamiseen, mutta kahden sairaanhoitopiirin johtajat arvioivat, että toistaiseksi hätäjarrun käytölle ei ole tarvetta. YLE-Uutiset. 14.12.2021. https://yle.fi/uutiset/3-12229385
Pääministeri Marin: Kolmansien rokotusten antamista vauhditettava – ”Työterveydenhuoltoa voitaisiin hyödyntää laajemmin”. Hallitus käsittelee koronatilannetta neuvottelussaan ensi viikon tiistaina 21. joulukuuta. Ilta=sanomat. 14.12.2021. https://www.is.fi/politiikka/art-2000008474610.html
Ministeri Kiuru: Maahantulorajoitukset kiristyvät – kolmansiin rokotuksiin on pyydetty apua puolustusvoimilta
Tänään kokoontunut sote-ministeriryhmä on tehnyt hallitukselle esityksen rajatoimien kiristämisestä sekä lisäavusta kunnille rokotusten järjestämistä varten. YLE-Uutiset. 14.12.2021. https://yle.fi/uutiset/3-12230314
Hollanti sulkee koulut etuajassa koronan takia. Hollannissa koululaiset pääsevät joululomalle viikkoa aiemmin heikentyneen koronatilanteen takia.Iltalehti. 14.12.2021. https://www.iltalehti.fi/ulkomaat/a/e41dd356-07b6-4a15-810a-93921e9794bb
Covid-19: Almost 100 ICU staff from Malaga hospital test positive after Christmas lunch. BMJ. 14.12.2021. https://www.bmj.com/content/375/bmj.n3085?
Why do Covid boosters offer greater protection against Omicron? Studies show three jabs are more effective than two as manufacturers work on variant-specific vaccines. Financial Times. 14.12.2021. https://www.ft.com/content/8a6a0ec8-fd07-49cd-a3f5-386a06269a5c
Merck’s COVID pill loses its lustre: what that means for the pandemic. Molnupiravir was initially heralded by public-health officials as a game-changer for COVID-19, but full clinical-trial data showed lower-than-expected efficacy. Nature. 13.12.2021. https://www.nature.com/articles/d41586-021-03667-0?
Meet the Vaccine Scientists: TIME’s Heroes of the Year. TIME. 13.12.2021. https://view.newsletters.time.com/?
Where I Live, No One Cares About COVID. Outside the world inhabited by the professional classes in a handful of major metropolitan areas, many Americans are leading their lives as if COVID is over. Atlantic. 13.12.2021. https://www.theatlantic.com/ideas/archive/2021/12/where-i-live-no-one-cares-about-covid/620958/
COVID-19-tutkimuskatsaus 13/2021. Valtioneuvosto. 13.12.2021. https://julkaisut.valtioneuvosto.fi/handle/10024/163688
Risikovurdering af omikron. Statens Seruminstitut. 12.12.2021. https://covid19.ssi.dk/-/media/arkiv/subsites/covid19/risikovurderinger/risikovurdering_omikron_121221_ssi.pdf?la=da
HUS: Neljä kymmenestä teho-osastolla hoidetuista koronapotilaista ei ollut palannut työhön tai harrastukseen kolme kuukautta kotiutumisen jälkeen. Teho-osastolle joutuneiden koronapotilaiden keski-ikä on koko epidemian ajalta 57 vuotta. Nuorempien ikäryhmien osuus tehohoidossa olevista koronapotilaista on kasvanut. YLE Uutiset. 11.12.2021. https://yle.fi/uutiset/3-12225995
Modelling the potential consequences of the Omicron. SARS-CoV-2 variant in England. 11.12.2021. https://cmmid.github.io/topics/covid19/reports/omicron_england/report_11_dec_2021.pdf
December 11 – 20
South Africa: early data suggest Omicron is more transmissible but less severe. The Conversation. 10.12.2021. https://theconversation.com/south-africa-early-data-suggest-omicron-is-more-transmissible-but-less-severe-173517?
Uusi tutkimus: tässä ajassa kaksi koronarokotetta ottaneiden suoja tartuntaa vastaan heikkenee. Koronarokotteiden teho hiipuu kolmen kuukauden jälkeen. Ilta=sanomat. 10.12.2021. https://www.is.fi/terveys/art-2000008464942.html?
Lopettaako Suomi rokotteiden tilaamisen? Hallitukselta vaaditaan vastauksia. Kokoomuksen Terhi Koulumies kysyy, aikooko Suomi todellakin peruuttaa rokotetilauksiaan. Verkkouutiset. 10.12.2021. https://www.verkkouutiset.fi/lopettaako-suomi-rokotteiden-tilaamisen-hallitukselta-vaaditaan-vastauksia/#773fc543
Filtration Efficiency of Face Masks Used by the Public During the COVID-19 Pandemic. JAMA Internal Medicine. 10.12.2021. https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2774265
The Hunt for a Single Shot to Defeat Omicron and All Coronaviruses. While the science is still in its early stages, the hardest part about developing a super-vaccine for all coronaviruses could be finding a way to pay for it. Bloomberg. 9.12.2021. https://www.bloomberg.com/news/features/2021-12-09/could-a-one-shot-coronavirus-vaccine-protect-you-from-all-variants
Alarm as almost 20% of South Africa’s healthcare workers contract Covid. Mail&Guardian. 9.12.2021. https://mg.co.za/coronavirus-essentials/2021-12-09-alarm-as-almost-20-of-south-africas-healthcare-workers-contract-covid/
16- and 17-year-olds are now eligible for a Pfizer/BioNTech Covid-19 vaccine booster. CNN Health. 9.12.2021. https://edition.cnn.com/2021/12/09/health/covid-booster-adolescents-fda-authorization/index.html?
STM huolestui Suomen kouluista ja lasten tartuntojen noususta – vetoomus THL:lle. WHO kehotti koronatoimiin peruskouluissa. STM huolestui Suomen tilanteesta ja vetoaa nyt THL:ään. Uusi Suomi. 9.12.2021. https://www.uusisuomi.fi/uutiset/stm-huolestui-suomen-kouluista-ja-lasten-tartuntojen-noususta-vetoomus-thllle/c1dd0e38-6941-44ca-a929-381ca8b4f7ea
Corona infections and air quality. More infections in poorly ventilated classrooms. Indoor air quality has an influence on how many corona virus infections occur there. This has now been shown for the first time in a pilot project involving Empa researchers in 150 primary school classrooms in Graubünden. The analysis also showed that the air quality in many classrooms is poor. The study concluded that regular ventilation of classrooms is therefore very important, even in winter months. EMPA. 9.12.2021. https://www.empa.ch/web/s604/covid-and-co2
Study shows benefit of regular classroom ventilation classroom. A Swiss study has found that poorly ventilated school classrooms record up to six times as many Covid-19 cases compared with those which are regularly aired. SwissInfo. 9.12.2021. https://www.swissinfo.ch/eng/society/study-shows-benefit-of-regular-classroom-ventilation/47179498
Ensimmäiset merkit omikronin kyvystä väistää rokotussuoja ilmi – Melatoniinista ja D-vitamiinista nyt apu pandemian hallintaan? (Mikko Paunio). Uusi Suomi. 8.12.2021. https://puheenvuoro.uusisuomi.fi/mikkopaunio/ensimmaiset-merkit-omikronin-kyvysta-vaistaa-rokotussuoja-ilmi-melatoniinista-ja-d-vitamiinista-nyt-apu-pandemian-hallintaan/
Pfizer antoi ensimmäisen arvion koronarokotteensa tehosta omikronmuunnosta vastaan. Kolmas annos Comirnaty-rokotetta herättää alustavien tulosten mukaan lupaavan paljon vasta-aineita omikronvarianttia vastaan. Mediuutiset. 8.12.2021. https://www.mediuutiset.fi/uutiset/mu/a4697e4f-84b6-45c1-8c32-dd112e1b581e?ref=newsletter:66d0&utm
Pfizer, BioNTech vaccine neutralises Omicron with three shots. Reuters. 8.12.2021. https://www.reuters.com/business/healthcare-pharmaceuticals/biontech-pfizer-say-test-shows-3-doses-vaccine-neutralise-omicron-2021-12-08/
PFIZER AND BIONTECH PROVIDE UPDATE ON OMICRON VARIANT. Pfizer. 8.12.2021. https://www.pfizer.com/news/press-release/press-release-detail/pfizer-and-biontech-provide-update-omicron-variant
Scientists Discover Harder-to-Detect Version of Omicron. Bloomberg. 8.12.2021. https://www.bloomberg.com/news/articles/2021-12-08/australia-finds-new-omicron-lineage-in-arrival-from-south-africa?cmpid=BBD120821_BIZ&utm_medium=email&utm_source=newsletter&utm_term=211208&utm_campaign=bloombergdaily
Tanska sulkee koulut. Aiemmin Tanska kertoi, että omikron leviää koko yhteiskunnassa. Iltalehti. 8.12.2021. https://www.iltalehti.fi/ulkomaat/a/55748a61-25a4-4f07-ade8-c03eb3c64d3d
Tallinnan-laivalta pääsi kävelemään suoraan Helsinkiin, vaikka kuulutus varoitti koronapassin tarkastuksesta. Katajanokan terminaalissa Helsingissä ei tarkastettu koronapasseja matkustajilta vaan jaettiin vanhentunutta ohjetta koronatestiin menemisestä. HS. 8.12.2021. https://www.hs.fi/kaupunki/art-2000008460200.html?share=583b747344b857ca56a08ac8b1522f47
COVID-19 Community Response Framework v4.0. New Zealand Government. 8.12.2021. https://www.health.govt.nz/system/files/documents/pages/covid-19_community_protection_framework_v4.0_8_dec_2021.pdf
Omicron coronavirus variant partly evades Pfizer vaccine’s protection, study shows. CNN Health. 8.12.2021. https://edition.cnn.com/2021/12/07/health/omicron-variant-pfizer-vaccine-south-africa-study/index.html
Omikronin vakavat tapaukset lisääntyvät räjähdysmäisesti. Verkkouutiset. 8.12.2021. https://www.verkkouutiset.fi/omikronin-vakavat-tapaukset-lisaantyvat-rajahdysmaisesti/#7e9b2b60
Reduced Neutralization of SARS-CoV-2 Omicron Variant by Vaccine Sera and monoclonal antibodies. medRxiv. 8.12.2021. https://www.medrxiv.org/content/10.1101/2021.12.07.21267432v1.full.pdf
Soomest sisse toodud haigusjuhtude arv kasvab. 8.12.2021. https://www.err.ee/1608429296/soomest-sisse-toodud-haigusjuhtude-arv-kasvab
Omikron paljasti leviämisensä saloja: Se on lainannut geneettistä koodia tavalliselta flunssalta. Koronan sairastaminen näyttää suojaavaan uudelta koronatartunnalta kolme kertaa huonommin, jos tartuttaja on deltamuunnoksen sijasta omikron. Mediuutiset. 8.12.2021. https://www.mediuutiset.fi/uutiset/mu/82024ba4-be86-433f-ad9d-c7783cbb8bad
Persistence of clinically relevant levels of SARS-CoV2 envelope gene subgenomic RNAs in non-immunocompromised individuals. International Journal of Infectious Diseases. 7.12.2021. https://www.ijidonline.com/article/S1201-9712(21)01206-6/fulltext
An upper bound on one-to-one exposure to infectious human respiratory particles. PLOS One. 7.12.2021. https://www.pnas.org/content/118/49/e2110117118
Anders Tegnell svarade på läsarnas frågor om corona. Expressen. 7.12.2021. https://www.expressen.se/nyheter/anders-tegnell-svarar-pa-dina-fragor-om-corona-/
Omicron variant of SARS-CoV-2 harbors a unique insertion mutation of putative viral or human genomic origin. OSF Preprints. 7.12.2021. https://osf.io/f7txy/
FHI: Alvorlig situasjon, men lite sannsynlig at omikron gir mer alvorlig sykdom. Det er ingen sikre tegn på at smittesituasjonen er i ferd med å snu. Folkehelseinstituttet (FHI) forventer en betydelig forverring for sykehusene selv om omikron trolig ikke gir mer alvorlig sykdom.NRK 7.12.2021. https://www.nrk.no/norge/fhi_-alvorlig-situasjon_-men-lite-sannsynlig-at-omikron-gir-mer-alvorlig-sykdom-1.15761037
Monet maat antavat jo keppiä rokottamattomille – Tässä lista 11 valtion käyttämistä kovista keinoista. Useat maat iskevät rokottamattomille sanktioita, kertoo uutistoimisto Bloomberg. Kovien keinojen joukossa ovat esimerkiksi lihavat sakot ja lomautukset. Mediuutiset. 7.12.2021. https://www.mediuutiset.fi/uutiset/monet-maat-antavat-jo-keppia-rokottamattomille-tassa-lista-11-valtion-kayttamista-kovista-keinoista/aed61f0a-b5ea-43d5-b1af-d9724675ff2c
Sollen auch Geimpfte und Genesene Maske tragen? Vielerorts gilt wieder Maskenpflicht. Eine neue Studie zeigt: FFP2-Masken schützen weit besser als medizinische Masken. Was Sie dazu wissen sollten. BaZ. 6.12.2021. https://www.bazonline.ch/sollen-auch-geimpfte-und-genesene-maske-tragen-447605008512
Omicron can reset the World’s Covid Strategy. Bloomberg. 5.12.2021. https://www.bloomberg.com/opinion/articles/2021-12-05/omicron-is-unavoidable-but-it-s-not-time-to-give-in-to-covid-panic
Prognosis. Initial Hospital Data in Omicron Epicenter Shows Milder Disease. Most patients in Covid wards have not been oxygen dependent. This seems different from earlier waves where fewer vaccinated. Bloomberg. 5.12.2021. https://www.bloomberg.com/news/articles/2021-12-05/initial-hospital-data-in-omicron-epicenter-shows-milder-disease?cmpid=BBD120621_MKT&utm_medium=email&utm_source=newsletter&utm_term=211206&utm_campaign=markets
Tshwane District Omicron Variant Patient Profile – Early Features. SAMRC. 4.12.2021. https://www.samrc.ac.za/news/tshwane-district-omicron-variant-patient-profile-early-features
Covid-19: Antibody boost after third dose varies greatly by vaccine, study finds. BMJ. 3.12.2021. doi: https://doi.org/10.1136/bmj.n3011
NHS forecasts 230,000 extra cases of PTSD in England due to Covid. Post-traumatic stress disorder diagnoses likely be among domestic abuse victims, care workers and the bereaved. Guardian. 3.12.2021. https://www.theguardian.com/society/2021/dec/03/nhs-forecasts-230000-extra-cases-of-ptsd-in-england-due-to-covid?utm_term=Autofeed&CMP=twt_gu&utm_medium&utm_source=Twitter#Echobox=1638513650
COVID-19: Omicron has ’substantial’ ability to evade immunity from previous coronavirus infection. Researchers at the National Institute for Communicable Diseases (NICD) warn their finding has important public health implications. Sky News. 3.12.2021. https://news.sky.com/story/covid-19-omicron-has-substantial-ability-to-evade-immunity-from-previous-coronavirus-infection-12484840
Disorders of Consciousness Associated With COVID-19
A Prospective Multimodal Study of Recovery and Brain Connectivity. Neurology. 18.12.2021. https://n.neurology.org/content/98/3/e315.long
KORONAVIRUS ON TAPPANUT KAHDEN VUODEN AIKANA JO YLI VIISI MILJOONAA IHMISTÄ. MUTTA MITEN SE SAI ALKUNSA? VASTA NYT SUURI SALAISUUS ALKAA RATKETA. HS Kuukausiliite.12. 3.12.2021. https://www.hs.fi/kuukausiliite/art-2000008369960.html?share=6e9bd8e471f70562f7ded6e3bbcaff37
Koronavirus leviää ilmateitse – onko sillä merkitystä?
On hämmästyttävää, miten vähän on varmaa tietoa siitä, millä lailla yleiset ylähengitysteiden tartuntataudit tarttuvat. Lyhyessä ajassa on käynyt selväksi, että aiemmin tunnettujen kosketus- ja pisaratartuntamekanismien lisäksi aerosolivälitteinen leviäminen on yleistä (1,2). Usein näiden reittien erottaminen ei ole helppoa. Infektoitunut voi tartuttaa vieressä seisovan terveen henkilön kaikilla kolmella tavalla. Kaukana tartunnan saaneesta olevat eivät voi saada tartuntatautia kosketus- tai pisaratartuntana – jäljelle jää siis aerosolitartunta.Lääkärilehti. 3.12.2021. https://www.laakarilehti.fi/ajassa/paakirjoitukset-tiede/koronavirus-leviaa-ilmateitse-ndash-onko-silla-merkitysta/?utm_medium=newsletter&utm_source=uk&utm_campaign=uk48pe-2021&m=NDA3NDYsZjg0YjM5MTczMzZhYWI4MDQ1YWIyMzMxOGU3YTcwNmM%3D
COVID-19 vaccine surveillance report. Week 48. UK Health Security Agency. 3.12.2021. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1037987/Vaccine-surveillance-report-week-48.pdf
Impact of community masking on COVID-19: A cluster-randomized trial in Bangladesh. Science. 2.12.2021. https://www.science.org/doi/10.1126/science.abi9069
Covid: Trigger of rare blood clots with AstraZeneca jab found by scientists. BBC. 2.12.2021. https://www.bbc.com/news/health-59418123
Prevalence of ongoing symptoms following coronavirus (COVID-19) infection in the UK : 2 December 2021
Estimates of the prevalence of self-reported long COVID and associated activity limitation, using UK Coronavirus (COVID-19) Infection Survey data. ONS. 2.12.2021. https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/prevalenceofongoingsymptomsfollowingcoronaviruscovid19infectionintheuk/2december2021
THL: Kolmas koronarokote annetaan kaikille täysi-ikäisille – Osa saa Comirnatyn, osa Spikevaxin. ”Koska kaksi koronarokotetta ei täysin estä tartuntoja, kolmansilla annoksilla saadaan edelleen ehkäistyä tartuntojen leviämistä myös nuoremmissa ikäryhmissä.” Mediuutiset. 2.12.2021. https://www.mediuutiset.fi/uutiset/thl-kolmas-koronarokote-annetaan-kaikille-taysi-ikaisille-osa-saa-comirnatyn-osa-spikevaxin/c412884b-f0b8-4060-9cb5-e5c0eadbeecf
Safety and immunogenicity of seven COVID-19 vaccines as a third dose (booster) following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK (COV-BOOST): a blinded, multicentre, randomised, controlled, phase 2 trial. 2.12.2021. Lancet. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)02717-3/fulltext
How bad is Omicron? What scientists know so far
COVID researchers are working at breakneck speed to learn about the variant’s transmissibility, severity and ability to evade vaccines. Nature 2.12.2021. https://www.nature.com/articles/d41586-021-03614-z?fbclid=IwAR3j_uqwpXhvx6W2afVU10mL0yqbhL6SxymfsWqooYj9FLdQpVKHpu8GUJY
THL suosittelee, että kolmansia koronarokoteannoksia aletaan tarjota kaikille 18 vuotta täyttäneille 5–6 kuukautta toisesta annoksesta. THL. 2.12.2021. https://thl.fi/-/thl-suosittelee-etta-kolmansia-koronarokoteannoksia-aletaan-tarjota-kaikille-18-vuotta-tayttaneille-5-6-kuukautta-toisesta-annoksesta
Aikuisista yli 99 % täysrokotettuja, mutta korona ryöpsähti silti – Gibraltarin tapaus ihmetyttää, mutta nyt ”tehosterokote todella toimii”. Pienen Gibraltarin koronatilanne nousee tällä hetkellä toistuvasti esiin rokotekeskusteluissa, koska maa on täysin rokotettu mutta tartunnat lähtivät silti eksponentiaaliseen kasvuun. Mediuutiset. 2.12.2021. https://www.mediuutiset.fi/uutiset/mu/b186ff7e-3f3e-421e-831e-e443b38ea80c?ref=newsletter:6bbc&utm_source=uutiskirje%40mediuutiset.fi&utm_medium=email&utm_campaign=MU-Uutiskirje-laakari
Omicron will likely ‘dominate and overwhelm’ the world in 3-6 months, doctor says. “Frankly, omicron will dominate and overwhelm the whole world in three to six months,” Singapore doctor Leong Hoe Nam told CNBC’s “Street Signs Asia.”
New vaccines targeting omicron are a “nice idea” but won’t be practical because of the transmissibility of the strain, he said.
Experts don’t know exactly how contagious the highly mutated omicron variant is, but the virus’ spike protein — which binds to human cells — has mutations associated with higher transmission and a decrease in antibody protection. CNBC. 2.12.2021. https://www.cnbc.com/2021/12/02/omicron-to-dominate-and-overwhelm-the-world-in-3-6-months-doctor-says.html
Sotrovimab: New COVID drug which cuts risk of hospitalisation and death by 79% approved for use in UK in people aged 12 years and older. Xevundy, also known as sotrovimab, has been approved for anyone aged 12 and over, who weighs more than 40kg. It is authorised for use in people who have a mild or moderate COVID infection and who are at risk of developing severe illness, Sky News. 2.12.2021. https://news.sky.com/story/sotrovimab-new-covid-drug-which-cuts-risk-of-hospitalisation-and-death-by-79-approved-for-use-in-uk-in-people-aged-12-years-and-older-12484329
Vanhojen näytteiden analyysi paljasti: omikron kiersi jo lokakuussa – kolme teoriaa muunnoksen synnystä. Omikron ei ole kehittynyt deltamuunnoksesta. Iltalehti. 1.12.2021. https://www.iltalehti.fi/ulkomaat/a/a02107be-f1ba-4201-b21f-68ed088ea524?utm_source=iltalehti.fi&utm_medium=email&utm_campaign=email_il_uutiskirje
Visualising SARS-CoV-2 transmission routes and mitigations. BMJ. 1.12.2021. https://www.bmj.com/content/375/bmj-2021-065312
Expert elicitation on the relative importance of possible SARS-CoV-2 transmission routes and the effectiveness of mitigations. BMJ. 1.12.2021. https://bmjopen.bmj.com/content/11/12/e050869
The Coronavirus in a Tiny Drop. NYT. 1.12.2021. https://www.nytimes.com/interactive/2021/12/01/science/coronavirus-aerosol-simulation.html
ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome. Science. 1.12.2021. https://www.science.org/doi/10.1126/sciadv.abl8213
COVID-19 Post-acute Sequelae Among Adults: 12 Month Mortality Risk. Frontiers in Medicine.. 1.12.2021. https://www.frontiersin.org/articles/10.3389/fmed.2021.778434/full
1 – 10. Joulukuuta
Misinformation Kills. Learn How to Counter It. University of Toronto. 30.11.2021. https://temertymedicine.utoronto.ca/event/misinformation-kills-learn-how-counter-it
Health Department-Reported Cases of Multisystem Inflammatory Syndrome in Children (MIS-C) in the United States. @IanRicksecker You may think, at least our children are safe. They are not. The CDC is tracking incidence of a life-threatening multisystem inflammatory syndrome in children following an acute COVID-19 infection, with 5,973 cases as of November 30, 2021. CDC Covid Data Tracker. updated 30.11.2021. https://covid.cdc.gov/covid-data-tracker/#mis-national-surveillance
Ilmanvaihto-ohjeistus varhaiskasvatuksen, opetuksen ja koulutuksen tilojen käytöstä vastaaville. THL. 30.11.2021. https://thl.fi/fi/web/ymparistoterveys/sisailma/koronavirus-ja-sisailman-turvallisuus/ilmanvaihto-ohjeistus-varhaiskasvatuksen-opetuksen-ja-koulutuksen-tilojen-kaytosta-vastaaville
Omicron variant found in two previous test samples. RIVM has found the Omicron variant in test samples taken in the Netherlands earlier in November. These samples were taken in the GGD test lanes on 19 and 23 November 2021. Saltro, the lab that analysed the tests, submitted the samples when requested by RIVM. RIVM. 30.11.2021. https://www.rivm.nl/en/news/omicron-variant-found-in-two-previous-test-samples?utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=newsAlerts&utm_term=coronavirus&utm_content=2021-12-01&apid=35182891&rvid=36e7b8c23c4809c80789f33a578dd1ee1d782a7186ca0f4d83fca8b14a1a75e7
COVID-19: Why the Omicron variant has scientists worried.
Scientists have detected cases of a new variant of SARS-CoV-2, which is the virus that causes COVID-19, in a number of countries. Omicron (B.1.1.529) has an unprecedentedly large number of mutations in the part of its genome that encodes a key section of its spike protein, which the virus uses to infect host cells. This suggests that Omicron may be able to evade some of the immune protection afforded by vaccines, many of which are based on the original spike protein, and past infections. Medical News Today. 29.11.2021. https://www.medicalnewstoday.com/articles/covid-19-why-the-omicron-variant-has-scientists-worried?utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=newsAlerts&utm_term=coronavirus&utm_content=2021-11-29&apid=35182891&rvid=36e7b8c23c4809c80789f33a578dd1ee1d782a7186ca0f4d83fca8b14a1a75e7
Why WHO skipped two letters of the Greek alphabet in naming Omicron. CNN Health. 29.11.2021. https://edition.cnn.com/2021/11/29/health/omicron-covid-variant-naming-cec/index.html
WHO Director-General’s opening remarks at the Special Session of the World Health Assembly – 29 November 2021. WHO. 29.11.2021. https://www.who.int/director-general/speeches/detail/who-director-general-s-opening-remarks-at-the-special-session-of-the-world-health-assembly—29-november-2021
Det svenska coronaexperimentet. Den negativa uppmärksamhet som statsepidemiolog Anders Tegnell, eller den svenska strategin över huvud taget, fick möta berodde till övervägande del på dödsfallen inom äldrevården. När många europeiska länder förbereder sig för att återinföra coronarestriktioner är läget i Sverige förhållandevis lugnt: Den svenske journalisten Johan Anderberg beskriver i en uppmärksammad bok hur den omdiskuterade svenska strategin föddes. HBL 29.11.2021. https://www.hbl.fi/artikel/det-svenska-coronaexperimentet/?utm_source=HBL%3As+nyhetsbrev&utm_campaign=25221686e9-veckans_kulturplock&utm_medium=email&utm_term=0_6233309afd-25221686e9-323144264
Professorit vetosivat sunnuntaina kolmannen koronarokotuksen kiirehtimiseksi. Iltalehden mukaan THL ja Kansallinen rokotusasiantuntijaryhmä (Krar) eivät ole noudattaneet hallituksen pyyntöjä nopeuttaa kolmannen koronarokotuskierroksen aloittamista alle 60-vuotiaiden keskuudessa. Mediuutiset. 29.11.2021. https://www.mediuutiset.fi/uutiset/mu/38fd6be0-71d9-48be-ad6d-59a8ed59356b?ref=newsletter:30ac&utm_source=uutiskirje%40mediuutiset.fi&utm_medium=email&utm_campaign=MU-Uutiskirje-laakari
Asiantuntijat vaativat HS:n mielipidekirjoituksessa kiirehtimään kolmansia rokotuksia – näkevät merkittävän ongelman THL:n Nohynekin arviossa. Lasse Lehtonen, Tuuli Lappalainen, Marjukka Myllärniemi ja Mark Daly kommentoivat THL:n Hanna Nohynekin sanomisia HS:n mielipidekirjoituksessa. Ilta=Sanomat. 29.11.2021. https://www.is.fi/kotimaa/art-2000008438117.html
IL:n tiedot: Kolmatta rokotekierrosta ei ole nopeutettu, vaikka hallitus vaatii. ”Kansallisen rokoteasiantuntijaryhmän (KRAR) sihteeri Hanna Nohynek on ollut laumasuoja-ajattelun vallassa, eikä ole halunnut aloittaa kolmatta rokotuskierrosta”, hallituslähde sanoo Iltalehdelle. Iltalehti. 28.11.2021. https://www.iltalehti.fi/politiikka/a/0541d1ca-f803-4de0-8c0a-5ba10b07820e
Soininvaara. 28.11.2021.
Neljäs aalto on pysäytettävä
DAILY HOSPITAL SURVEILLANCE (DATCOV) REPORT. Dept of Health, Govt of South Africa. 28.11.2021. https://www.nicd.ac.za/wp-content/uploads/2021/11/Datcov-National-Report-20211128.pdf
DAILY HOSPITAL SURVEILLANCE (DATCOV) REPORT
IS:n tiedot: Hallitus kaavailee rajoitustoimia ”kohtalaisen riskin” tilaisuuksiin – pöydällä valtakunnallinen etätyösuositus. THL:n ympärillä pyörivä keskustelu kiristää tunnelmia hallituksen sisällä. Yksi hallituslähde kritisoi THL:n suhtautumista kolmanteen rokotuskierrokseen. Toinen hallituslähde ihmettelee, miksi ”koronan hoidon ammattilaisten” uskottavuutta halutaan nakertaa. Ilta=Sanomat. 28.11.2021. https://www.is.fi/politiikka/art-2000008438790.html
South African doctor who raised alarm about omicron variant says symptoms are ‘unusual but mild’. Dr Angelique Coetzee noticed otherwise healthy patients showing unusual symptoms and worries how the new variant might hurt the elderly. The Telegraph. 27.11.2021. https://www.telegraph.co.uk/global-health/science-and-disease/south-african-doctor-raised-alarm-omicron-variant-says-symptoms/
A wind speed threshold for increased outdoor transmission of coronavirus: an ecological study. BMC Infectious Diseases. 27.11.2021. https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-021-06796-z
Tutkijat havaitsivat Etelä-Afrikassa huolestuttavan koronamuunnoksen, jota vastaan rokotteet eivät välttämättä suojaa tehokkaasti. Britannia ja Israel keskeyttävät muunnoksen vuoksi kaikki lennot eteläisen Afrikan maista. YLE Uutiset 26.11.-2021. https://yle.fi/uutiset/3-12204926
What We Know So Far About the New Variant of COVID-19 Raising Alarms Globally. TIME Health. 26.11.2021. https://time.com/6124074/covid-19-new-variant-europe/?utm_medium=email&utm_source=sfmc&utm_campaign=newsletter+coronavirus+default+ac&utm_content=+++20211129+++body&et_rid=95369053&lctg=95369053
Why don’t we just open windows. BMJ. 26.11.2021. doi: https://doi.org/10.1136/bmj.n2895
Koronan pikatestejä myydään nyt enemmän kuin koskaan aiemmin – infektiolääkäri (Irma Koivula, KYS): Oireettomalle pikkujoulujuhlijalle se ei ole vaihtoehto. Koronan pikatestien saatavuudessa on tällä hetkellä jonkin verran ongelmia. Apteekeista ja marketeista saatavat kotitestit ovat luotettavia, mutta oireettomien on turha käyttää niitä. YLE Uutiset. 26.11.2021. https://yle.fi/uutiset/3-12205306
Elapsed time since BNT162b2 vaccine and risk of SARS-CoV-2 infection: test negative design study. BMJ. 25.11.2021. https://doi.org/10.1136/bmj-2021-067873
COVID-19 vaccine weekly surveillance reports (weeks 39 to 47). Data on the real-world effectiveness and impact of the COVID-19 vaccines. Gov.UK. 25.11.2021. https://www.gov.uk/government/publications/covid-19-vaccine-weekly-surveillance-reports
Headlines play down the gravity of covid-19 in children. BMJ. 25.11.2021. https://www.bmj.com/content/375/bmj.n2826
Jos sulkee silmät, törmää seinään. Tuomas Aivelo, TIEDE. 25.11.2021. https://www.tiede.fi/blogit/kaiken-takana-loinen/jos-sulkee-silmat-tormaa-seinaa
Covid Conspiracy theorists: A spotters’ guide. Categorising Covid conspiracy theorists. You can do this at Thanksgiving, but don’t tell your antivax relatives. The Hat Tip. 25.11.2021. https://arieh.substack.com/p/covid-conspiracy-theorists-a-spotters
Scientists warn of new Covid variant with high number of mutations. The B.1.1.529 [Omicron] variant was first spotted in Botswana and six cases have been found in South Africa. Guardian. 24.11.2021. https://www.theguardian.com/world/2021/nov/24/scientists-warn-of-new-covid-variant-with-high-number-of-mutations
Koronarokotusten annosväli taas esillä, kun kolmansien annosten jakelu etenee – asiantuntija: kaikki riippuu siitä, mitä rokotusohjelmalla halutaan saada aikaan
Koronapandemian alkaessa harva tiesi RNA-rokotteista tai siitä, millaisella annosvälillä rokotteet tulisi antaa parhaan mahdollisen suojan varmistamiseksi. Siksi käytännöt ovat vaihdelleet eri puolilla maailmaa. YLE-Uutiset. 24.11.2021. https://yle.fi/uutiset/3-12199445?utm_source=newsletter&utm_medium=email&utm_campaign=newsdaily&utm_content=2021-11-24
Do vaccines protect against long COVID? What the data say. Vaccines reduce the risk of developing COVID-19 — but studies disagree on their protective effect against long COVID. Nature. 23.11.2021. https://www.nature.com/articles/d41586-021-03495-2
Assessment of Sequelae of COVID-19 Nearly 1 Year After Diagnosis. Frontiers in Medicine. 23.11.2021. https://www.frontiersin.org/articles/10.3389/fmed.2021.717194/full
Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy clinical trial. Science. 23.11.2021. https://www.science.org/doi/10.1126/science.abm3425
Tyksin tehohoidon ylilääkärillä on selkeä viesti rokotekeskusteluun: ”Jos yhteiskunta unohtaa tärkeimmän periaatteensa, ollaan matkalla kohti jotain aivan muuta kuin demokratiaa”
Tyksin tehohoidon ylilääkäri Mika Valtonen on huomannut, että etenkin nuoret lääkärit kokevat toisinaan voimakasta turhautumista hoitaessaan rokottamattomia potilaita. Helsingin Sanomat. 22.11.2021. https://www.hs.fi/hyvinvointi/art-2000008400399.html
COVID in Israel: Booster Shot Much More Effective Than First Two Shots, Officials Believe
Meanwhile, Israel’s pandemic advisory panel recommended a COVID booster shot to be administered to teens. Haaretz. 22.11.2021. https://www.haaretz.com/israel-news/covid-in-israel-booster-shot-much-more-effective-than-first-two-shots-1.10404207
Kuusamon ja Suomen koronatilanne ja käytännön ratkaisuvaihtoehdot. Koronatilanteesta keskustelemassa muun muassa ympäristöterveyden tutkimusprofessori emeritus Matti Jantunen, keuhkosairauksien professori Marjukka Myllärniemi, empiirisen makrotaloustieteen professori Antti Ripatti ja taloustieteen ja terveystaloustieteen tutkijatohtori Liisa T. Laine. 22.11.2021. https://docs.google.com/presentation/d/1Za6SpkoJvdwF_A3VaXSeIwlf82IlGRq2pFweB-69a78/edit#slide=id.g1026011fdb7_1_18
Israel testasi varautumista koronaviruksen ”tuomiopäivän-varianttiin” – nämä heikkoudet Omega-harjoitus paljasti. MTV Uutiset. 21.11.2021. https://www.mtvuutiset.fi/artikkeli/israel-testasi-varautumista-koronaviruksen-tuomiopaivan-varianttiin-nama-heikkoudet-omega-harjoitus-paljasti/8294924?fbclid=IwAR1uE8gsKjB55uLTiQLpEvECTVWhMjHzsgqpKHVKbbl4wmmgFIHqPtgGayY#gs.he4msi.
November 21 – 30
Persistent symptoms following SARS-CoV-2 infection amongst children and young people: A meta-analysis of controlled and uncontrolled studies. Journal of Infection. 19.11.2021. https://www.journalofinfection.com/article/S0163-4453(21)00555-7/fulltext#%20
CDC recommends Covid-19 boosters for all adults. CNN Health. 19.11.2021. https://edition.cnn.com/2021/11/19/health/covid-vaccine-boosters-fda-cdc/index.html?
The epidemiological relevance of the COVID-19-vaccinated population is increasing, Lancet. 19.11.2021. https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(21)00258-1/fulltext
Effectiveness of public health measures in reducing the incidence of covid-19, SARS-CoV-2 transmission, and covid-19 mortality: systematic review and meta-analysis. BMJ. 18.11.2021. https://www.bmj.com/content/375/bmj-2021-068302
Public health measures for covid-19. BMJ. 19.11.2021. https://www.bmj.com/content/375/bmj.n2729
Dissecting the early COVID-19 cases in Wuhan. Science. 18.11.2021. https://www.science.org/doi/10.1126/science.abm4454?
Mapping how the 100 billion cells in the brain all fit together is the brave new world of neuroscience. The Conversation. 18.11.2021. https://theconversation.com/mapping-how-the-100-billion-cells-in-the-brain-all-fit-together-is-the-brave-new-world-of-neuroscience-170182
New analyses of two AZD7442 COVID-19 Phase III trials in high-risk populations confirm robust efficacy and long-term prevention. AstraZeneca. 18.11.2021. https://www.astrazeneca.com/content/astraz/media-centre/press-releases/2021/new-analyses-of-two-azd7442-covid-19-phase-iii-trials-in-high-risk-populations-confirm-robust-efficacy-and-long-term-prevention.html?utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=newsAlerts&utm_term=coronavirus&utm_content=2021-11-19&apid=35182891&rvid=36e7b8c23c4809c80789f33a578dd1ee1d782a7186ca0f4d83fca8b14a1a75e7
Multifactorial seroprofiling dissects the contribution of pre-existing human coronaviruses responses to SARS-CoV-2 immunity. Nature. 18.11.2021. https://www.nature.com/articles/s41467-021-27040-x
Do childhood colds help the body respond to COVID?
A mechanism known as ‘original antigenic sin’ protects some people from flu; whether it helps immune reactions to coronaviruses is still unclear. Nature. 18.11.2021. https://www.nature.com/articles/d41586-021-03087-0?fbclid=IwAR2vyBm4igzgZihWRgE_P3C-Q_SjOW544TPr9itRss8dPsQFZSM9GR0T6F4
Results of COVID-19 Vaccine Effectiveness Studies: An Ongoing Systematic Review. Weekly Summary Tables. International Vaccine Access Center,
Johns Hopkins Bloomberg School of Public Health andWorld Health Organization. 18.11.2021. https://view-hub.org/sites/default/files/2021-11/COVID19%20Vaccine%20Effectiveness%20Transmission%20Impact%20Studies%20-%20Summary%20Tables_20211118_0.pdf
US vaccine rollout was close to optimal at reducing deaths and infections, according to a model comparing 17.5 million alternative approaches. The Conversation. 17.11.2021. https://theconversation.com/us-vaccine-rollout-was-close-to-optimal-at-reducing-deaths-and-infections-according-to-a-model-comparing-17-5-million-alternative-approaches-171656
Covid-19 transmission in fitness centers in Norway – a randomized trial. National Library of Medicine. (BMC Public Health). 16.11.2021. https://pubmed.ncbi.nlm.nih.gov/34789188/
PD-1 blockade counteracts post–COVID-19 immune abnormalities and stimulates the anti–SARS-CoV-2 immune response. JCI Insight. 16.11.2021. https://insight.jci.org/articles/view/146701/figure/4
Efficacy of FFP3 respirators for prevention of SARS-CoV-2 infection in healthcare workers. eLife. 16.11.2021. https://elifesciences.org/articles/71131
Neutralising antibody titres as predictors of protection against SARS-CoV-2 variants and the impact of boosting: a meta-analysis. Lancet. 15.11.2021. https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(21)00267-6/fulltext
SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis. Nature Communications. 15.11.2021. https://www.nature.com/articles/s41467-021-26910-8.epdf?
Lehdistötiedote. Valtakunnallinen #TaasMennään-joukkoliikennekampanja siirtyy heikentyneen epidemiatilanteen takia. 12.11.2021. https://www.lvm.fi/-/valtakunnallinen-taasmennaan-joukkoliikenne-kampanja-siirtyy-heikentyneen-epidemiatilanteen-takia-1575633
Increased risk of SARS-CoV-2 reinfection associated with emergence of the Omicron variant in South Africa. medRxiv. 11.11.2021. https://www.medrxiv.org/content/10.1101/2021.11.11.21266068v2
November 11 – 20
COVID-19 tests: Does accuracy vary throughout the day? Medical News Today. 10.11.2021. https://www.medicalnewstoday.com/articles/covid-19-tests-does-accuracy-vary-throughout-the-day?utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=newsAlerts&utm_term=coronavirus&utm_content=2021-11-10&apid=35182891&rvid=36e7b8c23c4809c80789f33a578dd1ee1d782a7186ca0f4d83fca8b14a1a75e7
Israel aloitti kolmannet koronarokotukset ensimmäisenä maailmassa – näin tautitilanne muuttui. Yli neljä miljoonaa israelilaista on saanut jo kolmannen koronapiikin, ja maan koronatilanne näyttää taas hyvältä. Iltalehti. 10.11.2021. https://www.iltalehti.fi/ulkomaat/a/c7b6a42f-c101-4133-8e13-7b5a94a9249b?utm_source=iltalehti.fi&utm_medium=email&utm_campaign=email_il_uutiskirje
Covid-19: Pandemic reduced life expectancy in most developed countries, study finds. BMJ. 10.11.2021. https://www.bmj.com/content/375/bmj.n2750
Covid vaccination to be mandatory for NHS staff in England from spring 2021. BMJ. 10.11.2021. https://www.bmj.com/content/375/bmj.n2733?=&utm_source=adestra&utm_medium=email&utm_campaign=usage&utm_content=daily&utm_term=text
COVID-19 tests: Does accuracy vary throughout the day?. Medical News Today. 10.11.2021. https://www.medicalnewstoday.com/articles/covid-19-tests-does-accuracy-vary-throughout-the-day?utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=newsAlerts&utm_term=coronavirus&utm_content=2021-11-10&apid=35182891&rvid=36e7b8c23c4809c80789f33a578dd1ee1d782a7186ca0f4d83fca8b14a1a75e7
Modeling COVID-19 Mortality Across 44 Countries: Face Covering May Reduce Deaths. AJPM. 10.11.2021. https://www.ajpmonline.org/article/S0749-3797(21)00557-2/fulltext
Israel aloitti kolmannet koronarokotukset ensimmäisenä maailmassa – näin tautitilanne muuttui. Yli neljä miljoonaa israelilaista on saanut jo kolmannen koronapiikin, ja maan koronatilanne näyttää taas hyvältä. IL. 10.11.2020. https://www.iltalehti.fi/ulkomaat/a/c7b6a42f-c101-4133-8e13-7b5a94a9249b?utm_source=iltalehti.fi&utm_medium=email&utm_campaign=email_il_uutiskirje
Unvaccinated Texans 40 times as likely to die of covid as those fully vaccinated in 2021, study says. WP. 9.11.2021. https://www.washingtonpost.com/health/2021/11/09/texas-unvaccinated-deaths-higher-covid/?fbclid=IwAR1NX9H-oGUUHSsZCzmk-XeE3hRWd5ifZ7E3_sCItv2X9tRBOuSMl6zr9gU
Six-month sequelae of post-vaccination SARS-CoV-2 infection: a retrospective cohort study of 10,024 breakthrough infections. @IanRicksecker, In the words of the study authors, “vaccination does not appear to be protective against .. long-COVID features, arrhythmia, joint pain, type 2 diabetes, liver disease, sleep disorders, and mood and anxiety disorders.” medRxiv. 8.11.2021. https://doi.org/10.1101/2021.10.26.21265508
COVID-19 Cases and Deaths by Vaccination Status. Texas Department of State Health Services. 8.11.2021. https://documentcloud.adobe.com/link/review?uri=urn:aaid:scds:US:85395206-6268-4cb8-8259-7dc12a039bcb#pageNum=1
Cohort study of Covid-19 vaccine effectiveness among healthcare workers in Finland, December 2020 – October 2021. medRxiv. 8.11.2021. https://www.medrxiv.org/content/10.1101/2021.11.03.21265791v2
Coronavirus (COVID-19) booster vaccine. NHS. 8.11.2021. ttps://www.nhs.uk/conditions/coronavirus-covid-19/coronavirus-vaccination/coronavirus-booster-vaccine/
Researchers uncover gene that doubles risk of death from COVID-19. University of Oxford. 5.11.2021. https://www.ox.ac.uk/news/2021-11-05-researchers-uncover-gene-doubles-risk-death-covid-19
Pfizer antiviral slashes COVID-19 hospitalizations. Given early in infection, experimental pill prevents severe disease, trial suggests. Science. 5.11.2021. https://www.science.org/content/article/pfizer-antiviral-slashes-covid-19-hospitalizations?utm_campaign=news_daily_2021-11-08&fbclid=IwAR0AdiPmZUWY0_e6w4bVRQvrONQQ6Wld81CNQcYDa4S-_ZoPZQxHzFHxwB4
SARS-CoV-2 vaccine protection and deaths among US veterans during 2021. Science. 4.11.2021. https://www.science.org/doi/10.1126/science.abm0620
Pfizerin koronalääke osoittautui erittäin tehokkaaksi – Lupahakemus lähtee Yhdysvaltain lääkeviranomaisille.
Yhtiö hakee lääkkeelle erikoislupaa jo ennen kolmannen vaiheen suurta ihmistutkimusta. Mediuutiset. 5.11.2021. https://www.mediuutiset.fi/uutiset/mu/15b7065f-2fb6-4ffb-afc7-0beb1821b71f?ref=newsletter:4f94&utm_source=uutiskirje%40mediuutiset.fi&utm_medium=email&utm_campaign=MU-Uutiskirje-laakari
Remdesivir, Get Out Of The Way: Pfizer’s Antiviral Shines. American Council on Sciences and Health. 5.11.2021. https://www.acsh.org/news/2021/11/05/remdesivir-get-out-way-pfizers-antiviral-shines-15923?fbclid=IwAR1RU9lENChgjcIoNdMAC7b5_cVEOoMrYfYeIT1sl_OnQ7KxNb-Lt7T4i24
WHO varoittaa: Eurooppaan ”tautien talvi” – koronaennätyksiä rikotaan nyt monessa maassa. WHO:n mukaan Eurooppa on pandemian keskus. Iltalehti. 4.11.2021. https://www.iltalehti.fi/ulkomaat/a/e87e81bf-d34e-43f5-95ed-91254d26490c
Rapid assessment of SARS-CoV-2 evolved variants using virus-like particles. Science. 4.11.2021. https://www.science.org/doi/10.1126/science.abl6184
Prevalence of ongoing symptoms following coronavirus (COVID-19) infection in the UK: 4 November 2021. Estimates of the prevalence of self-reported long COVID and associated activity limitation, using UK Coronavirus (COVID-19) Infection Survey data. Office for National Statistics. 4.11.2021. https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/prevalenceofongoingsymptomsfollowingcoronaviruscovid19infectionintheuk/4november2021
Are vaccine passports and covid passes a valid alternative to lockdown? BMJ. 3.11.2021. https://www.bmj.com/content/375/bmj.n2571
Kansalaispulssi – 28. kierros. Verkkokysely 27.10.–1.11.2021
15–74-vuotiaat mannersuomalaiset. VNK Strategiaosasto.
3.11.2021. https://valtioneuvosto.fi/documents/10184/49252202/Kansalaispulssi+3.11.2021.pdf/d202b3a1-53a3-6e95-37ee-7461c5bd5154/Kansalaispulssi+3.11.2021.pdf?version=1.1&t=1636110644012&download=true
Russia’s vaccine disinformation has let down its own people
Poor handling has intensified an enduring distrust of state authorities. FT. 3.11.2021. https://www.ft.com/content/dcf6e11c-28f7-4541-b8d9-f91d4825da8a
COVID-19: Antidepressant cuts risk of hospitalization, death by 32%. Medical News Today. 2.11.2021. https://www.medicalnewstoday.com/articles/covid-19-antidepressant-cuts-risk-of-hospitalization-death-by-32?utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=newsAlerts&utm_term=coronavirus&utm_content=2021-11-03&apid=35182891&rvid=36e7b8c23c4809c80789f33a578dd1ee1d782a7186ca0f4d83fca8b14a1a75e7
Nur Spanische Grippe und Aids tödlicher als Corona
Fünf Millionen Menschen sind bislang durch Sars-CoV-2 gestorben, so die offizielle Zahl. Ein Vergleich der Virus-Epidemien unserer Zeit. BaZ. 2.11.2021. https://www.bazonline.ch/nur-spanische-grippe-und-aids-toedlicher-als-corona-682150625606?utm_source=sfmc&utm_medium=email&utm_campaign=BS_ED_9_ENG_EM_NL_XX_DERABEND_XX_2021-11-022&utm_term=2021-11-02&utm_content=1726982_
A Review and Autopsy of Two COVID Immunity Studies. Brownstone Institute. 2.11.2021. https://brownstone.org/articles/a-review-and-autopsy-of-two-covid-immunity-studies/?s=03
Covid-19: Researcher blows the whistle on data integrity issues in Pfizer’s vaccine trial. BMJ 2.11.2021. https://www.bmj.com/content/375/bmj.n2635
Risk factors for developing COVID-19: a population-based longitudinal study (COVIDENCE UK). BMJ Thorax. 2.11.2021. https://thorax.bmj.com/content/early/2021/11/02/thoraxjnl-2021-217487
Global Covid-19 deaths surpass five million. CNN Workd. 1.11.2021. https://edition.cnn.com/2021/11/01/world/covid-19-5-million-deaths-globally-intl-hnk/index.html?utm_term=1635762508890005700fe1b99&utm_source=cnn_Five+Things+for+Monday%2C+November+1%2C+2021&utm_medium=email&bt_ee=SgX8PRGbWYAjEV7myThR%2FnkIQM4WcqXhocXrTUNqsmweh92Y21i2BGgsGBh5quHT&bt_ts=1635762508892
Deaths involving COVID-19 by vaccination status, England: deaths occurring between 2 January and 24 September 2021. Weekly age-standardised mortality rates and age-specific rates for deaths involving COVID-19 by vaccination status; deaths occurring between 2 January and 24 September 2021 in England. Office for National SStatistics. 1.11.2021. https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/bulletins/deathsinvolvingcovid19byvaccinationstatusengland/deathsoccurringbetween2januaryand24september2021?fbclid=IwAR0RhDFqc3NYS4NulNhe1Y43fLQaFCNxxJ_3ravBHIEYdbKTByjuvEE8xYU
November 1-10
Taloustieteilijät: Ilman koronasulkuja taloudellisia tappioita ja kuolleita olisi tullut paljon enemmän. Suurin osa kulutuksen laskusta on tullut ihmisten varovaisuudesta, ei yhteiskunnan suluista, Ylen haastattelemat koronatutkimukseen perehtyneet taloustieteilijät arvioivat. Norjassa tehdyn tutkimuksen mukaan kuolleita olisi kymmenkertainen määrä Ruotsin kaltaisella koronapolitiikalla. YLE Uutiset. 31.10.2021. https://yle.fi/uutiset/3-12165691
THL ehdottaa koronapassia sote-työntekijöille – näin kommentoivat kansanedustajat terveysalalta
Iltalehti kysyi kolmelta sote-taustaiselta kansanedustajalta, mitä mieltä he ovat THL:n ehdotuksesta käyttää koronapassia sote-alan työntekijöihin. Iltalehti. 31.10.2021. https://www.iltalehti.fi/politiikka/a/34c3f822-cbe5-48f5-9cd6-f929ef16507e?utm_source=iltalehti.fi&utm_medium=email&utm_campaign=email_il_uutiskirje
The Removal of Airborne Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Other Microbial Bioaerosols by Air Filtration on Coronavirus Disease 2019 (COVID-19) Surge Units [Kun hepa-ilmanpuhdistimet olivat päällä, ilmasta ei voitu tunnistaa koronavirusta. Kun ne sammutettiin, virusta löytyi taas ilmasta]. Clinical Infectious Diseases. 30.10.2021. https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciab933/6414657?login=false
RKI warnt vor Superspreading: 8-Punkte-Check zeigt, wann das Risiko besonders hoch ist. Das Robert-Koch-Institut warnt vor weiter steigenden Corona-Zahlen – vor allem durch Kontakte in Innenräumen. Um besser einschätzen zu können, wie hoch das Risiko in welcher Umgebung ist, hat Virologe Hendrik Streeck gemeinsam mit Aerosol-Forschern und Lungenmediziner den ”Lufthygiene”-Guide veröffentlicht. Focus. 30.10.2021. https://m.focus.de/gesundheit/coronavirus/virologe-streeck-und-aerosol-experten-lufthygiene-check-wo-die-corona-gefahr-hoch-ist-und-wo-nicht_id_24340093.html
Vaaran paikka. Virustutkimus auttaa suojelemaan terveyttä. Joskus virukset karkaavat laboratorio-onnettomuuden seurauksena. Wuhanissa Kiinassa suunniteltiin riskialtista koetta, jolla olisi voinut olla vakavia seurauksia. YLE-Uutiset. 30.10.2021. https://yle.fi/uutiset/3-12156805
Suomessa ensimmäiset Delta plus -löydökset – tämä aiempaa tartuttavammasta koronamuunnoksesta tiedetään.
Terveyden ja hyvinvoinnin laitoksen tietojen mukaan ensimmäiset löydökset Delta plus -variantista tulivat jo elokuussa. Viranomaiset eivät kerro yksilönsuojan takia paikkakuntia, kun tartuntoja on alle viisi. MTV-Uutiset. 29.10.2021. https://www.mtvuutiset.fi/artikkeli/suomessa-ensimmaiset-delta-plus-loydokset-tama-aiempaa-tartuttavammasta-koronamuunnoksesta-tiedetaan/8276114#gs.io00h0
Community transmission and viral load kinetics of the SARS-CoV-2 delta (B.1.617.2) variant in vaccinated and unvaccinated individuals in the UK: a prospective, longitudinal, cohort study. Lancet Infectious Diseases. 29.10.2021. https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00648-4/fulltext
Contact and SARS-CoV-2 Infections Among College Football Athletes in the Southeastern Conference During the COVID-19 Pandemic. JAMA. 29.10.2021. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2785602?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102921
Effectiveness of a third dose of the BNT162b2 mRNA COVID-19 vaccine for preventing severe outcomes in Israel: an observational study. Lancet. 29.10.2021. DOI:https://doi.org/10.1016/S0140-6736(21)02249-2
Suomessa ensimmäiset Delta plus -löydökset – tämä aiempaa tartuttavammasta koronamuunnoksesta tiedetään. Terveyden ja hyvinvoinnin laitoksen tietojen mukaan ensimmäiset löydökset Delta plus -variantista tulivat jo elokuussa. Viranomaiset eivät kerro yksilönsuojan takia paikkakuntia, kun tartuntoja on alle viisi. MTV. 29.10.2021. https://www.mtvuutiset.fi/artikkeli/suomessa-ensimmaiset-delta-plus-loydokset-tama-aiempaa-tartuttavammasta-koronamuunnoksesta-tiedetaan/8276114#gs.eosbkn
The plexiglass barrier problem. Justin Ling: Vaccines, masks and ventilation are working. So why do governments keep doubling-down on the measures that don’t effectively stop COVID? MacLean’s 29.10.2021. https://www.macleans.ca/society/health/the-plexiglass-barrier-problem/
We must call out childism in covid-19 policies. BMJ. 29.10.2021. https://www.bmj.com/content/375/bmj.n2641
Community transmission and viral load kinetics of the SARS-CoV-2 delta (B.1.617.2) variant in vaccinated and unvaccinated individuals in the UK: a prospective, longitudinal, cohort study. Lancet. 29.10.2021. https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00648-4/fulltext#%20
Did ‘Eat Out to Help Out’ increase COVID-19 cases in England? Medical News Today. 28.10.2021. https://www.medicalnewstoday.com/articles/did-eat-out-to-help-out-increase-covid-19-cases-in-england?utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=newsAlerts&utm_term=coronavirus&utm_content=2021-11-01&apid=35182891&rvid=36e7b8c23c4809c80789f33a578dd1ee1d782a7186ca0f4d83fca8b14a1a75e7
Yökoulusta levinneet koronatartunnat hätkähdyttivät ihmisoikeusjuristin – Martin Scheinin: ”Pidän aiheellisena, että asiassa tehdään tutkintapyyntö”
Ihmisoikeusjuristi Martin Scheininin mukaan viranomaisten mahdolliset laiminlyönnit tartuntatautilain noudattamisessa on syytä punnita oikeudessa. Lappajärvellä Etelä-Pohjanmaalla koronatartunnat levisivät alakoululaisten yökoulussa. YLE Uutiset. 27.10.2021. https://yle.fi/uutiset/3-12162621
Immunocompromised may need a fourth Covid-19 shot, CDC says. CNN Health. 27.10.2021. https://edition.cnn.com/2021/10/26/health/covid-19-fourth-dose-for-the-immunocompromised/index.html
Noin 20-vuotiaat rokottamattomat nuoret joutuneet koronan takia keskussairaalaan – keuhkot huonossa kunnossa. Ilkka-Pohjalainen kertoo, että Seinäjoen keskussairaalassa on tällä viikolla hoidettu muutamaa vasta noin 20-vuotiasta koronapotilasta, joiden keuhkot ovat huonossa kunnossa. IS. 27.10.2021. https://www.is.fi/kotimaa/art-2000008350962.html
Breakthrough infections can lead to long COVID; genes may explain critical illness in young, healthy adults. Reuters. 27.10.2021. https://www.reuters.com/business/healthcare-pharmaceuticals/breakthrough-infections-can-lead-long-covid-genes-may-explain-critical-illness-2021-10-27/
Finland’s Success in Combating Covid-19: Mastery, Miracle or Mirage? SSERN. 27.10.2021. https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3909237#
F.D.A. Panel Recommends Covid Shots for Children 5 to 11
Covid-19 was “the eighth-highest killer of kids in this age group over the past year,” said a C.D.C. official in favor of broader authorization. NYT. 26.10.2021. https://www.nytimes.com/2021/10/26/us/fda-pfizer-covid-vaccine-kids.html?smid=tw-share
Ansiktsskydd behövs fortfarande. HBL. 26.10.2021. https://www.hbl.fi/artikel/ansiktsskydd-behovs-fortfarande/
Type of ultraviolet light most effective at killing coronavirus is also the safest to use around people. The Conversation. 26.10.2021. https://theconversation.com/type-of-ultraviolet-light-most-effective-at-killing-coronavirus-is-also-the-safest-to-use-around-people-169602?utm
Terveydenhuollon työnantajalla tulisi olla oikeus tietää työntekijän rokotussuojasta, vaatii Lääkäriliitto – ”Olisi helpompaa, jos tiedon näkisi kysymättä”, sanoo Husin Ruotsalainen. Husin apulaisylilääkäri Eeva Ruotsalaisen mukaan on selvä potilasturvallisuusriski, jos esimerkiksi rokottamaton työntekijä tuo tartuntoja hoivakotiin. HE. 25.10.2021. https://www.hs.fi/kotimaa/art-2000008356424.html?share=661dc8d4856bafc4d6eaff0d8f33925b
Professori varoittaa keskustelun kärjistymisestä: Nykyinen puhetapa voi lisätä rokotusvastaisuutta. Rokotusta vaille jääminen ei ole aina tietoisen harkinnan tulos, sanoo professori Nelli Hankonen. HS. 25.10.2021. https://www.hs.fi/hyvinvointi/art-2000008349588.html?share=3f242d9d3e6a5400d076f918969a2de2
Evaluation of the relative virulence of novel SARS-CoV-2 variants: a retrospective cohort study in Ontario, Canada. CMAJ. 25.10.2021. https://www.cmaj.ca/content/193/42/E1619
Effectiveness of Covid-19 Vaccination Against Risk of Symptomatic Infection, Hospitalization, and Death Up to 9 Months: A Swedish Total-Population Cohort Study. Lancet. 25.10.2021. https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3949410
SARS-CoV-2 infects human adipose tissue and elicits an inflammatory response consistent with severe COVID-19, BioRxiv. 24.10.2021. https://www.biorxiv.org/content/10.1101/2021.10.24.465626v1
Health leaders accuse ministers of bungling rollout of UK Covid booster jab
Vaccine drive described as ‘fragmented’ with half the people eligible for third dose yet to come forward. FT. 22.10.2021. https://amp.ft.com/content/1f57838a-24d2-40d5-b314-2d8345a6e001?__twitter_impression=true
Suomi purki koronarajoituksia, vaikka THL:n käyrät varoittivat uhkaavista seurauksista – tautiekologi: ”Masentavinta, että meni juuri niin kuin ajateltiin”. THL mallinsi elokuussa, miten sairaalahoito kuormittuisi, jos rajoituksia purettaisiin 80 prosentin rokotekattavuuden koittaessa. Hoidon tarve olisi noussut merkittävästi. Rajoitukset purettiin, kun kattavuus oli vielä selvästi vähemmän, noin 70 prosenttia. YLE-Uutiset. 22.10.2021. https://yle.fi/uutiset/3-12155829?utm_source=newsletter&utm_medium=email&utm_campaign=newsdaily&utm_content=2021-10-23
Safe traveling in public transport amid COVID-19. Science. 22.10.2021. https://www.science.org/doi/10.1126/sciadv.abg3691?utm_campaign=SciMag&utm_source=Social&utm_medium=Twitter
Assessment of Cognitive Function in Patients After COVID-19 Infection. JAMA. 22.10.2021. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2785388?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102221
The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells. Nature Neuroscience. 21.10.2021. https://www.nature.com/articles/s41593-021-00926-1
Pfizer boosters show 95.6% efficacy against Covid, study finds. Results hailed as ‘important’ but duration of protection still unknown. FT. 21.10.2021. https://amp.ft.com/content/d4e58d38-37d6-40cd-9d72-6b9bfd0a3683?
PFIZER AND BIONTECH ANNOUNCE PHASE 3 TRIAL DATA SHOWING HIGH EFFICACY OF A BOOSTER DOSE OF THEIR COVID-19 VACCINE. Pfizer. 21.11.2021. https://www.pfizer.com/news/press-release/press-release-detail/pfizer-and-biontech-announce-phase-3-trial-data-showing
The American founders didn’t believe your sacred freedom means you can do whatever you want – not even when it comes to vaccines and your own body. The Conversation. 21.10.2021. https://theconversation.com/the-american-founders-didnt-believe-your-sacred-freedom-means-you-can-do-whatever-you-want-not-even-when-it-comes-to-vaccines-and-your-own-body-169924?utm
Voisiko Suomeen tulla rokotepakko? Oikeusoppineet hämmästelevät, miksi kissa ei ole jo pöydällä. Rokotepakko on vaikeampi asia poliittisesti kuin juridisesti. Rokotevelvoitteen käyttöönotto vaatisi lääketieteellistä arviointia ja poliittista keskustelua. Rokotevelvoitteen käyttöönotto vaatisi lääketieteellistä arviointia ja poliittista keskustelua. Rokotevelvoitteen käyttöönotto vaatisi lääketieteellistä arviointia ja poliittista keskustelua. Iltalehti. 21.10.2021. https://www.iltalehti.fi/kotimaa/a/ea67d28e-2250-4cd3-b6a4-303cdd357acb?utm
October 21-31
Moscow orders unvaccinated over-60s to stay home for 4 months as Russia’s Covid-19 crisis deepens. CNN World. 20.10.2021. https://edition.cnn.com/2021/10/20/europe/russia-elderly-stay-home-order-record-deaths-intl/index.html?utm
Koulu pantiin jatkuviin koronatesteihin: Yllätys lasten tartunnoissa. Tutkimuksen perusteella lasten rooli taudin levittäjinä voi olla oletettua suurempi. Verkkouutiset. 20.10.2021. https://www.verkkouutiset.fi/koulu-pantiin-jatkuviin-koronatesteihin-yllatys-lasten-tartunnoissa/#53d13ff6
COVID-19 pandemic drove flu to historic lows, and may have eliminated one virus type completely. ABC Science News. 20.10.2021. https://amp.abc.net.au/article/100546836?__twitter_impression=true
Miten koronan torjuntaa pitäisi mitata? Professorin (Lillrank) laskelman mukaan pelastetut elinvuodet ovat maksaneet kymmeniä kertoja kohtuuhintaa enemmän. Koronaa on torjuttu kohtuuttomalla hinnalla, kun käyttöön otettiin laajat sulkutoimet, professori Paul Lillrank sanoo. Koronan kustannusten mittaaminen on kuitenkin vaikeaa, koska emme tiedä mitä olisi tapahtunut, jos olisimme tehneet toisin. YLE-Uutiset. 20.10.2021. https://yle.fi/uutiset/3-12150546?utm_source=newsletter&utm_medium=email&utm_campaign=ylefi&utm_content=2021-10-20
Covid-19-tapaukset lisääntyvät koulujen avautuessa – Etenkin silloin, kun opettajat ja oppilaat eivät käytä maskeja. Koulut lisäävät yhteisön tartuntoja, mutta hyvä uutinen on, että suhteellisen yksinkertaiset lieventävät toimenpiteet voivat tehdä kouluista paljon turvallisempia paikkoja, kirjoittaa Tutkijalta-palstalla epidemiologi ja biostatistikko Zoë Hyde Länsi-Australian yliopistosta. TM. 20.10.2021. https://tekniikanmaailma.fi/covid-19-tapaukset-lisaantyvat-koulujen-avautuessa-etenkin-silloin-kun-opettajat-ja-oppilaat-eivat-kayta-maskeja/
HS: Teho-osaston lääkäriltä lohduton arvio tulevasta koronatilanteesta – ”Jos meininki jatkuu tällaisena…” Turun yliopistollisen sairaalan osastonlääkäri Jussi Heiro antaa Helsingin Sanomissa lohduttoman arvionsa tulevasta koronatilanteesta. IS. 20.10.2021. https://www.is.fi/turun-seutu/art-2000008345611.html
The association of opening K–12 schools with the spread of COVID-19 in the United States: County-level panel data analysis. PNAS. 19.10.2021. https://www.pnas.org/content/118/42/e2103420118
Without Covid-19 jab, ‘reinfection may occur every 16 months’
Reports grow of repeat infection as experts warn prevalence among school pupils puts older people at risk. Guardian. 19.10.2021. https://www.theguardian.com/world/2021/oct/19/without-covid-19-jab-reinfection-may-occur-every-16-months-say-scientists
Piispa Teemu Laajasalo kannusti ihmisiä ottamaan rokotteen – yli 200 ihmistä erosi kirkosta. Eilen kirkosta erosi 242 ihmistä. Iltalehti. 19.10.2021. https://www.iltalehti.fi/kotimaa/a/ce2d6484-f917-41bb-af07-6b7cdf4b9245?utm
Covid-19: Silencing health workers, researchers, and journalists caused unnecessary deaths, says Amnesty. 19.10.2021. https://www.bmj.com/content/375/bmj.n2552?=&utm_source=adestra&utm_medium=email&utm
Excess risk and clusters of symptoms after COVID-19 in a large Norwegian cohort. medRxiv. 18.10.2021. https://www.medrxiv.org/content/10.1101/2021.10.15.21265038v1.full.pdf
Effectiveness of public health measures in reducing the incidence of covid-19, SARS-CoV-2 transmission, and covid-19 mortality: systematic review and meta-analysis. BMJ. 18.11.2021. https://www.bmj.com/content/375/bmj-2021-068302
swedish study shows covid vaccines drop below zero efficacy on spread by about 200 days. protection from severe covid dropped as well. bad cattitude. 18.10.2021. https://boriquagato.substack.com/p/swedish-study-shows-covid-vaccines
Nelli Hankonen blog: Albertan koronasyksy 2021. 18.10.2021. https://blogs.helsinki.fi/nhankone/2021/10/18/albertan-koronasyksy-2021/
Emeritusprofessori esittää Suomeen Italian ja Ranskan tyylistä ’de facto’ rokotuspakkoa. Käytännössä rokotuspakko voidaan Matti Jantusen mukaan toteuttaa samalla mallilla kuin esimerkiksi Italiassa ja Ranskassa. Mediuutiset. 18.10.2021. https://www.mediuutiset.fi/uutiset/mu/4646944e-c239-436d-8ce6-b5bf63cc436e?ref=newsletter:434f&utm
Mask-wearing linked to 53% cut in Covid incidence, global study finds. Researchers said results highlight the need to continue with face coverings, social distancing and handwashing alongside vaccine programmes. Guardian. 17.10.2021. https://www.theguardian.com/world/2021/nov/17/wearing-masks-single-most-effective-way-to-tackle-covid-study-finds?CMP=Share_iOSApp_Other
TERVEYSPSYKOLOGIA: Koronataistelu muuttuu sissisodaksi. Matti TJ Heino blog. 17.10.2021. https://mattiheino.com/2021/10/17/sissisota/
Nyt puhuu tehohoitolääkäri: ”Emme jaksa enää”. Tehohoitolääkärin mukaan hoitohenkilökunta on aivan loppu.
THL on julkaissut rokotekampanjavideoita – kehottavat ihmisiä hakemaan rokotteen. Iltalehti. 17.10.2021. https://www.iltalehti.fi/koronavirus/a/35a746af-e1df-4212-8680-2a26e4636375
Victoria and NSW schools are reopening amid Covid outbreaks – what can be learned from overseas? In Victoria, once the lockdown is lifted, all children in year 3 and above will be required to wear masks indoors. Experts say there are important lessons for Australia in order to reduce the rate of transmission and hospitalisation. Guardian. 16.10.2021. https://www.theguardian.com/australia-news/2021/oct/17/victoria-and-nsw-schools-are-reopening-amid-covid-outbreaks-what-can-be-learnt-from-overseas?utm_term=Autofeed&CMP=twt_gu&utm_medium&utm_source=Twitter#Echobox=1634411450
Asiantuntija ryöpyttää Suomen päättäjiä: ”Onko meillä siis tyhmempi kansa josta osa ansaitseekin sairastaa ja kuolla?” Tuuli Lappalaisen mukaan sekä viranomaiset että poliitikot ovat antaneet ennenaikaisia ja ylioptimistisia lupauksia, ja niiden peruminen nyt tekee kipeää. Uusi Suomi. 16.10.2021. https://www.uusisuomi.fi/uutiset/us/b0aaf526-55e4-485c-af62-0e83d3d04b13?ref=twitter:286d
Lääkäriltä suorat sanat: Kohta nämä hoidetaan itkun kanssa.
Tutkijalääkäri sanoo olevansa äärimmäisen pettynyt poliittiseen johtamiseen.Verkkouutiset. 16.10.2021. https://www.verkkouutiset.fi/laakarilta-suorat-sanat-kohta-nama-hoidetaan-itkun-kanssa/#b7eaa73f
UK falls behind European peers in battle against Covid ahead of winter
Deaths and hospital admissions remain stubbornly high in Britain as the continent reports record lows. FT. 16.10.2021. ttps://amp.ft.com/content/34582534-4510-4d45-bcba-2f9e04005309?__twitter_impression=true
K-12 schools without mask mandates in Michigan saw 62% more coronavirus spread. Detroit Free Press. 15.10.2021. https://amp.freep.com/amp/8422532002?__twitter_impression=true
Suomi värjäytyi punaiseksi Euroopan tautikeskuksen kartalla – matkustamista ei suositella. Kahden viime viikon aikana Suomessa on raportoitu 7 763 uutta koronatartuntaa, mikä on 1 632 tartuntaa enemmän kuin edellisten kahden viikon aikana. IS. 15.10.2021. https://www.is.fi/kotimaa/art-2000008336966.html
Coronavirus (COVID-19) Infection Survey, UK: 15 October 2021
Estimates for England, Wales, Northern Ireland and Scotland. This survey is being delivered in partnership with the University of Oxford, University of Manchester, Public Health England and Wellcome Trust. This study is jointly led by the ONS and the Department for Health and Social Care (DHSC) working with the University of Oxford and Lighthouse laboratory to collect and test samples. Office of National Atatistics. 15.10.2021. https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/coronaviruscovid19infectionsurveypilot/15october2021
How many lives have coronavirus vaccines saved? We used state data on deaths and vaccination rates to find out. The Conversation. 15.10.2021. https://theconversation.com/how-many-lives-have-coronavirus-vaccines-saved-we-used-state-data-on-deaths-and-vaccination-rates-to-find-out-169513?utm
FDA vaccine advisers recommend emergency use authorization for booster dose of Moderna’s Covid-19 vaccine. CNN Health. 15.10.2021. https://edition.cnn.com/2021/10/14/health/fda-vaccine-advisers-moderna-thursday/index.html?utm
Covid-19 Breakthrough Infections in Vaccinated Health Care Workers. @IanRicksecker, But if you’re counting on vaccination to feel safe, there’s even more bad news. A study of Israel healthcare workers found that “Most breakthrough cases were mild or asymptomatic, although 19% had persistent symptoms (>6 weeks).” N MEngl J Med. 14.10.2021. https://doi:10.1056/NEJMoa2109072
Covid-19: Fatal errors, not fatalism, created UK’s public health disaster. BMJ. 14.10.2021. https://www.bmj.com/content/375/bmj.n2497/rapid-responses
Covid-19 Breakthrough Infections in Vaccinated Health Care Workers. NEJM. 14.10.2021. https://www.nejm.org/doi/full/10.1056/NEJMoa2109072
Covid and flu: what do the numbers tell us about morbidity and deaths? BMJ. 14.11.2021. https://www.bmj.com/content/375/bmj.n2514?=&utm_source=adestra&utm_medium=email&utm_campaign=usage&utm_content=daily&utm_term=text
Children could be dangerous carriers of virus. Study finds kids to be potential spreaders of COVID-19 and emerging variants. Harvard Gazette. 14.10.2021. https://news.harvard.edu/gazette/story/2021/10/study-confirms-kids-as-spreaders-of-covid-19-and-emerging-variants/
A public health strategy for SARS-CoV-2, grounded in science, should guide Swiss schools through the coming winter. Swiss Medical Weekly. 14.10.2021. https://smw.ch/article/doi/SMW.2021.w30086
Molnupiravir vs. COVID-19: Will the drug live up to the hype?
In the search for effective COVID-19 treatments, many drugs have failed to live up to their early promise. In a recent trial, seen as an important advance, the oral antiviral drug molnupiravir halved the risk of hospital admissions and deaths from COVID-19. Medical News Today explored the evidence to see whether this optimism is justified. Medical News Today. 14.10.2021. https://www.medicalnewstoday.com/articles/molnupiravir-vs-covid-19-will-the-drug-live-up-to-the-hype?utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=MNT%20Daily%20News&utm_content=2021-11-06&apid=32395010&rvid=348b31007bc4905a3c503d64d5572c0dac87e7263eba83389e708a2774ce1afc
Koronapotilaiden sairaalahoito tulisi järjestää uudella tavalla. Jos jatkamme nykyisellä tavalla, muiden sairauksien hoitovelka kasvaa. HS. 14.10.2021. https://www.hs.fi/mielipide/art-2000008329522.html?share=88fac73056eeaf8accb772a13979fe12
SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro. MDPI. 13.10.2021. https://www.mdpi.com/1999-4915/13/10/2056/htm?fbclid=IwAR1Dhvhw7sYLQSIe5Ll62ERQGvyITyASRIpimMfEmVN7He5e29ZeXgxwXLU
Rokoteasiantuntijat pohtivat kolmatta rokotekierrosta tänään – THL:n Nohynek: Tulee miettiä, onko lisäannoksen terveyshyöty oikeassa suhteessa hintaan. THL:n alainen Kansallinen rokotusasiantuntijaryhmä (Krar) kokoontuu pohtimaan kolmansia koronarokoteannoksia keskiviikkona. HS. 13.10.2021. https://www.hs.fi/kotimaa/art-2000008323890.html?s=03
A cross-sectional analysis of meteorological factors and SARS-CoV-2 transmission in 409 cities across 26 countries. Nature Communications. 13.10.2021. https://www.nature.com/articles/s41467-021-25914-8
Husin ylilääkäri kertoo, keitä sairaaloissa nyt koronataudin vuoksi hoidetaan – ”Rokotukset ovat edenneet huonosti muiden kuin nuorimpien kohdalla”
HS:n uusi grafiikka seuraa rokottamattomien osuutta sairaaloissa. HS. 13.10.2021. https://www.hs.fi/kaupunki/art-2000008328276.html?share=591c82ab6b86a7f0a3d744187315dfbf
Think a mild case of COVID-19 is no big deal? Think again. New research shows concerning effects of the virus, even in asymptomatic cases. Colorado Newsline. 13.10.2021. https://coloradonewsline.com/2021/10/13/mild-case-of-covid-19-no-big-deal-think-again/
In Conversation: The neurocognitive impact of long COVID
For many people, long COVID has associations with serious neurological and neurocognitive impairments, a phenomenon sometimes known as neuro-COVID. Why does this happen, and who is most at risk? In this Special Feature and podcast, we speak to two researchers and a person with lived experience of neuro-COVID to find out more. Medical News Today. 13.10.2021. https://www.medicalnewstoday.com/articles/long-covid-brain-fog-what-do-we-know-about-the-neurocognitive-impact?utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=MNT%20Daily%20News&utm_content=2021-11-06&apid=32395010&rvid=348b31007bc4905a3c503d64d5572c0dac87e7263eba83389e708a2774ce1afc
Kun sairaalahoidon tarve kasvoi keväällä tällaiseksi, hallitus julisti ”sulkutilan” – Voiko Marin vielä perääntyä yhteiskunnan avaamisesta? Pahenevasta tautitilanteesta huolimatta hallituksella on korkea kynnys ajaa kireämpiä rajoituksia. Koronapassi voi tulla laajasti käyttöön vain, jos rajoituksia kiristetään. HS. 12.10.2021. https://www.hs.fi/politiikka/art-2000008325861.html?share=1ee867d6a284bfce9b7b6b71e4265abd
Maailmalla koronalääkettä tilataan jo vauhdilla, Suomessa ei vieläkään – Uhkana on lääkkeiden tuleva saatavuus. Koronalääkkeen myyntiin tulosta on ollut tietoja ilmassa jo pitkään. Suomessa tilanteeseen ei ole nopeasti havahduttu. Mediuutiset. 12.10.2021. https://www.mediuutiset.fi/debatti/maailmalla-koronalaaketta-tilataan-jo-vauhdilla-suomessa-ei-vielakaan-uhkana-on-laakkeiden-tuleva-saatavuus/2eb405b1-9d16-4610-a7cf-8edd9b2f39ad
Your Wednesday Briefing. A damning report on Britain’s virus response. NYT. 13.10.2021.
COVID lesson: trust the public with hard truths. When governments assume that people will panic, that exacerbates the pandemic. Nature 12.10.2021. https://www.nature.com/articles/d41586-021-02758-2?fbclid=IwAR2vAE-gZRvXkhO1aEXj2A56im8qi81qSQWPyNrorh40JmautC5ywUrftJA
‘The real problem is the repetition of mistakes’: scientists react to Covid inquiry. Senior figures say failure to prevent second wave was inexcusable given what was known about the virus. Guardian. 12.10.2021. https://www.theguardian.com/world/2021/oct/12/the-real-problem-is-the-repetition-of-mistakes-scientists-react-to-covid-enquiry?CMP=Share_iOSApp_Other
Covid response ‘one of UK’s worst ever public health failures’.
Early handling and belief in ‘herd immunity’ led to more deaths, Commons inquiry finds. Guardian. 12.10.2021. https://www.theguardian.com/politics/2021/oct/12/covid-response-one-of-uks-worst-ever-public-health-failures?CMP=Share_iOSApp_Other
What the Future May Hold for the Coronavirus and Us
Viral evolution is a long game. Here’s where scientists think we could be headed. NYT. 12.10.2021.
Infektiolääkärin epätoivoinen vetoomus koronarokotusten puolesta: ”Hetken näytti hyvältä ja melkein juhlittiin, mutta nyt laivan pohja vuotaa”. Tampereen yliopistollisen keskussairaalan infektiolääkäri kertoo MTV Uutisille rokottamattomien vaikeasta koronatilanteesta. Syyskuussa lähes 80 prosenttia sairaalahoidossa olevista oli rokottamattomia. Lääkäri Reetta Huttusen mukaan hätkähdyttävää on, että merkittävä osuus sairaalaan joutuvista potilaat ei ole iäkkäitä, vaan nuoria tai keski-ikäisiä. MTV-Uutiset. 12.10.2021. https://www.mtvuutiset.fi/artikkeli/infektiolaakarin-epatoivoinen-vetoomus-koronarokotusten-puolesta-hetken-naytti-hyvalta-ja-melkein-juhlittiin-mutta-nyt-laivan-pohja-vuotaa/8262410
Selvitys: Britannia aloitti koronasulun liian myöhään, mikä oli merkittävä kansanterveydellinen epäonnistuminen maan historiassa. Raportin mukaan tämä oli yksi merkittävimmistä kansanterveydellisistä epäonnistumisista maan historiassa. HS. 12.10.2021. https://www.hs.fi/ulkomaat/art-2000008326330.html?share=011911d95bd7a841169809f72bf1e2f8
How did we get here: what are droplets and aerosols and how far do they go? A historical perspective on the transmission of respiratory infectious diseases. The Royal Society. 12.10.2021. https://doi.org/10.1098/rsfs.2021.0049
Transmission of SARS-CoV-2 After COVID-19 Screening and Mitigation Measures for Primary School Children Attending School in Liège, Belgium. JAMA. 12.10.2021. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2784812
FDA scientists neutral on Moderna Covid-19 vaccine booster ahead of key meeting. STAT. 12.10.2021. https://www.statnews.com/2021/10/12/fda-scientists-moderna-covid-vaccine-booster/#:~:text=Events-,FDA%20scientists%20neutral%20on%20Moderna%20Covid%2D19,booster%20ahead%20of%20key%20meeting&text=Food%20and%20Drug%20Administration,vaccine%20in%20documents%20released%20Tuesday.
Covid-19: Government’s handling of pandemic had “big mistakes,” MPs say. BMJ 12.10.2021. https://www.bmj.com/content/375/bmj.n2487?=&utm
Covid response ‘one of UK’s worst ever public health failures’. Early handling and belief in ‘herd immunity’ led to more deaths, Commons inquiry finds. Guardian. 12.10.2021. https://www.theguardian.com/politics/2021/oct/12/covid-response-one-of-uks-worst-ever-public-health-failures
Lessons for all from the UK’s Covid mishandling. Politicians and scientists succumbed to a flawed, fatalistic groupthink. FT. 12.10.2021. https://amp.ft.com/content/6369ab78-19ec-4a81-858d-a5f318496306?__twitter_impression=true
Covid-19: Is New Zealand’s switch in policy a step forward or a retreat?. BMJ. 11.10.2021. https://www.bmj.com/content/375/bmj.n2476?=&utm_source=adestra&utm_medium=email&utm
Life-saving COVID Drug Regeneron in Israel – but Most Patients Won’t Take It. Some Israelis are COVID anti-vaxxers who distrust Regeneron, but others just don’t see the need or are talked out of it at the last moment. 11.10.2021. https://www.haaretz.com/israel-news/life-saving-covid-wonder-drug-comes-to-israel-but-most-patients-won-t-take-it-1.10282942?utm
Kouvolan koululaisille tuli helpotuksen päivä, kun maskeja ei enää tarvitse käyttää – suurin askel kuitenkin vielä odottaa.
Kouvolassa on tänään maanantaina luovuttu koulujen ja päiväkotien maskisuosituksesta. Ainakin ensimmäisenä päivänä kasvomaski vielä oli monen yllä.. YLE-Uutioset 11.10.2021. https://yle.fi/uutiset/3-12138579
October 11-20
Here’s what Bay Area doctors say about how COVID affects the brain. San Francisco Chronicle. 10.10.2021. https://www.sfchronicle.com/health/article/How-COVID-affects-the-brain-Bay-Area-doctors-16520440.php
Korona vie yhä enemmän sairaalaan: Satakunnassa joudutaan erityisjärjestelyihin. Hoitoon joutuvat ovat valtaosin rokottamattomia. Alle 60-vuotiaita lähes puolet. Kokemäkijokilaakson Uutiset. 10.10.2021. https://www.kokemaenjokilaakso.fi/2021/10/10/korona-vie-yha-enemman-sairaalaan-satakunnassa-joudutaan-erityisjarjestelyihin/
Kraftig ökning av psykisk ohälsa under pandemin. Dagens Nyheter. 10.10.2021. https://www.dn.se/vetenskap/kraftig-okning-av-psykisk-ohalsa-under-pandemin/
Sanna Marin otti riskin, joka näyttää toteutuneen – Tehohoidon ”kriittinen piste” alkaa lähestyä. Sanna Marinin hallitus purki viikko sitten isosti koronarajoituksia ja sen jälkeen tautiluvut kohosivat. Riski näyttää realisoituneen, mutta seuraako tästä rajoitusten palauttamisia, mistä STM jo vihjaisi? Viranomaiset ja pääministeri antavat nyt varsin erilaista viestiä tilanteesta. Mediuutiset. 9.10.2021. https://www.mediuutiset.fi/uutiset/mu/5e432005-aff9-4eb2-8e59-25167af51d64?utm_term=Autofeed&utm_medium=Social&utm_source=Twitter#Echobox=1633764599
Latviassa julistettiin kolmen kuukauden poikkeustila koronan takia. Kyseessä on kolmas kerta, kun Latviassa otetaan käyttöön poikkeustila koronapandemian takia. Poikkeustila koskee erityisesti rokottamattomia. HS. 9.10.2021. https://www.hs.fi/ulkomaat/art-2000008321748.html
Meilahden koronapotilaiden tehohoitopaikat ovat loppumassa – rokottamattomien asenne herättää tuskaa linjajohtajassa: ”En enää keksi, miten voisi vaikuttaa”. Korona: Hus tehohoidon linjajohtaja Minna Bäcklund sanoo olevansa huolissaan rokottamattomien asenteesta. Leikkaukset siirtyvät, kun koronapotilaiden hoito vie paikat. Helsingin Uutiset. 9.10.2021. https://www.helsinginuutiset.fi/paikalliset/4323606
They Had the Vaccines and a Plan to Reopen. Instead They Got Cold Feet. Singapore’s experience offers lessons for other countries that want to reduce pandemic restrictions but have yet to deal with widespread infections. NYT 8.10.2021. https://www.nytimes.com/2021/10/08/world/asia/singapore-vaccine-covid.html
COVID-19 is linked to new diabetes cases—but long-term problems could be more severe.
In addition to driving new cases of diabetes, the virus may be directly damaging the pancreas in ways that could lead to chronic inflammation and even cancer. National Geographic. 8.10.2021. https://www.nationalgeographic.com/science/article/the-many-ways-covid-19-seems-to-be-harming-the-pancreas?
Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study. Lancet. 7.10.2021. https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(21)00383-0/fulltext
Pfizer Asks F.D.A. to Authorize Its Covid-19 Vaccine for Children 5 to 11. The agency has promised to move quickly on the request and tentatively plans to meet on Oct. 26 to consider it. A decision could come soon after Halloween.NYT. 7.10.2021. https://www.nytimes.com/2021/10/07/us/politics/pfizer-fda-authorization-children-5-11.html
SARS-CoV-2 RNA in the Cerebrospinal Fluid of a Patient with Long COVID. SACE Journals. 7.10.2021. https://journals.sagepub.com/doi/full/10.1177/20499361211048572?fbclid=IwAR1XpHp1_Dabj_NS817YKAAq1lrKzyw5BrfTwNwFfpg6L7ZtDKYjhu-n2Vw&
SARS-CoV-2 emerging variants display enhanced syncytia formation. @IanRicksecker, Also worrisome are syncytia, where an infected cell extrudes its own spike protein and takes over its neighbors, fusing together to create a large multi-nucleus cell. Delta’s particular aptitude for this may partly explain its severity. NewsMedical. 6.10.2021. https://www.news-medical.net/news/20211006/SARS-CoV-2-emerging-variants-display-enhanced-syncytia-formation.aspx
ECDC:n raportti: Suomi kuuluu maihin, joissa alhainen rokotustaso voi aiheuttaa tartuntojen lisääntymistä ja sairaaloiden kuormittumista. Terveyden ja hyvinvoinnin laitoksen (THL) johtava asiantuntija Mia Kontio kertoo, ettei Suomen jääminen EU- ja ETA-maiden keskiarvon alle ollut yllätys. HS. 6.10.2021. https://www.hs.fi/kotimaa/art-2000008312773.html?share=20625478db85708dd292fc597ff19233
HS muuttaa koronauutisoinnin painopisteen pois tartuntamääristä kohti elämää koronan kanssa. ”Ylhäältä annetun luvan sijasta jokaisen pitää itse päättää, että nyt on turvallista elää enemmän. Korona loppuu siinä vaiheessa, kun kukin meistä itse päättää lakata pelkäämästä”, kirjoittaa HS:n toimituspäällikkö Esa Mäkinen. Helsingin Sanomat. 6.10.2021. https://www.hs.fi/kotimaa/art-2000008243137.html
Kannattaisiko rokotetun nyt altistaa itsensä koronalle? – ”Tätä on mietitty”, toteaa ylilääkäri. Kaksi koronarokoteannosta antaa todennäköisesti hyvän suojan vakavaa tautia vastaan, mutta täydellinen turva se ei ole. Iltalehti. 5.10.2021. https://www.iltalehti.fi/terveysuutiset/a/b9f7d947-af3f-4a5f-812c-f8b7f018cd88
Pääkaupunkiseudulle oma suositus: Käytä maskia julkisissa liikennevälineissä, ihmispaljoudessa ja sairaana. Helsinki, Espoo ja Vantaa luopuvat samalla päiväkotien, koulujen ja oppilaitosten altistumistietojen raportoinnista. YLE-Uutiset. 5.10.2021. https://yle.fi/uutiset/3-12129425
One-year Risks and Burdens of Incident Cardiovascular Disease in COVID-19: Cardiovascular Manifestations of Long COVID. Research Square. 5.10.2021. https://www.researchsquare.com/article/rs-940278/v1
Koronaepidemia voi poikia syöpärokotteen – ”Näitä ei olisi ikinä muuten syöpätutkimuksessa havaittu”, sanoo Docrateen ylilääkäri. Pfizerin ja Modernan koronarokotteesta tutusta mRNA-tekniikasta haetaan nyt apua vähän kaikkeen, vesikauhusta ja kystisestä fibroosista syöväntorjuntaan. Mediuutiset 4.10.2021. https://www.mediuutiset.fi/uutiset/mu/afa6a794-391d-4005-8081-87aa9d4a5ed2?
THL-johtajan ja pääministerin ulostulot puhuttavat lääkäreitä: ”Viranomaisellakin on jo vähän hätä kädessä”. ”Tämä on marinilainen Suomi: arvoiltaan kova, lapsia, rokottamattomia ja sairaita sortava yhteiskunta. Rokotetuilla vain oikeuksia, ei mitään velvollisuuksia”, ylilääkäri Harri Tohmo kuvailee. Mediuutiset. 4.10.2021. https://www.mediuutiset.fi/uutiset/mu/6709c919-39be-4291-9aab-17f2ea72cf0a?ref=newsletter:d73a
Study confirms SARS-CoV-2 transmission through aerosols, and effectiveness of masks in preventing transmission. MedicalNewsToday. 4.10.2021.
Specific UV light wavelength could offer low-cost, safe way to curb COVID-19 spread. PhysOrg. 4.10.2021. https://phys.org/news/2021-10-specific-uv-wavelength-low-cost-safe.html
Detailed reconstruction of the Iranian COVID-19 epidemic reveals high attack rates of SARS-CoV-2 in several provinces. medRxiv. 4.10.2021. https://www.medrxiv.org/content/10.1101/2021.10.04.21264540v1
Battling Delta, New Zealand Abandons Its Zero-Covid Ambitions. The country is changing course seven weeks into a lockdown that has failed to end the outbreak and tested the patience of many residents. NYT. 4.10.2021. https://www.nytimes.com/2021/10/04/world/australia/new-zealand-covid-zero.html?smid=tw-nytimes&smtyp=cur
Israel Tightens COVID ’Green Pass’ Rules, Sparking Protest. Israel has restricted its COVID Green Pass to allow only those who have received a vaccine booster dose or recently recuperated from coronavirus to enter indoor venues. US News and World Report. 3.10.2021. https://www.usnews.com/news/health-news/articles/2021-10-03/israel-tightens-covid-green-pass-rules-sparking-protest
The 2,000-year-old airborne disease theory that blinded Covid experts
As a result precautions such as wearing masks and better ventilation in public spaces were tragically delayed, says a new report. The Telegraph. 2.10.2021. The 2,000-year-old airborne disease theory that blinded Covid experts (telegraph.co.uk)
Pääministeri Marin kertoo Ylelle, miksi hallitus ohitti THL:n näkemyksen ravintoloista: ”Rokotetuilla on täysi oikeus normaalimpaan elämään”. Sanna Marin myöntää, että ravintoloita koskevien koronarajoitusten reipas lieventäminen voi näkyä tautitapausten kasvuna. Hän ei kuitenkaan pidä koronatilannetta niin huonona, että entisille rajoituksille olisi perusteita. YLE Uutiset. 2.10.2021. https://yle.fi/uutiset/3-12126037
COVID-19 Associated Hepatitis in Children (CAH-C) during the second wave of SARS-CoV-2 infections in Central India: Is it a complication or transient phenomenon. MedRxiv. 2.10.2021. https://www.medrxiv.org/content/10.1101/2021.07.23.21260716v6.full.pdf
Alberta acted like the pandemic was over. Now it’s a cautionary tale for Canada. Saskatchewan faces similar surge in hospitals, while Manitoba is at risk from low vaccination rates. CBC. 2.10.2021. https://www.cbc.ca/news/health/alberta-fourth-wave-surge-hospitals-icu-covid-19-1.6197263
Exhaled particles from nanometre to millimetre and their origin in the human respiratory tract. medRxiv. 1.10.2021. https://www.medrxiv.org/content/10.1101/2021.10.01.21264333v1
The durability of immunity against reinfection by SARS-CoV-2: a comparative evolutionary study. Lancet Microbe. 1.10.2021. https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(21)00219-6/fulltext
Covid-19: Lancet investigation into origin of pandemic shuts down over bias risk. BMJ. 1.10.2021. https://www.bmj.com/content/375/bmj.n2414
U.S. Coronavirus Death Toll Surpasses 700,000 Despite Wide Availability of Vaccines. The latest Covid-19 deaths were concentrated in the South, and included more younger people than before. Every age group under 55 saw its highest death toll of the pandemic this August. NYT. 1.10.2021. https://www.nytimes.com/2021/10/01/us/us-covid-deaths-700k.html
Monitoraggio Fase 2. Report settimanale. Report 72. Sintesi nazionale. ISS. 1.10.2021. https://www.salute.gov.it/imgs/C_17_monitoraggi_81_0_fileNazionale.pdf
Tyksissä jouduttiin perumaan leikkauksia, sillä teholla oli rokottamattomia koronapotilaita. Turun Sanomat. 1.10.2021. https://www.ts.fi/uutiset/5440236
Vaccinating against covid and flu at same time is safe, study shows. BMJ. 1.10.2021. https://www.bmj.com/content/375/bmj.n2411?=&utm
Merck and Ridgeback’s Investigational Oral Antiviral Molnupiravir Reduced the Risk of Hospitalization or Death by Approximately 50 Percent Compared to Placebo for Patients with Mild or Moderate COVID-19 in Positive Interim Analysis of Phase 3 Study. MERCK. 1.10.2021. https://www.merck.com/news/merck-and-ridgebacks-investigational-oral-antiviral-molnupiravir-reduced-the-risk-of-hospitalization-or-death-by-approximately-50-percent-compared-to-placebo-for-patients-with-mild-or-moderat/
SARS-CoV-2 infections elicit higher levels of original antigenic sin antibodies compared to SARS-CoV-2 mRNA vaccinations. MedRxiv. 1.10.2021. https://www.medrxiv.org/content/10.1101/2021.09.30.21264363v1
In Portugal, There Is Virtually No One Left to Vaccinate. Portugal is among the most highly vaccinated countries in the world. Vice Adm. Henrique Gouveia e Melo, who led the campaign, said there was a key to his success: Keep politics out of it. NYT. 1.10.2021. https://www.nytimes.com/2021/10/01/world/europe/portugal-vaccination-rate.html
October 1-10
Reliability of COVID- 19 symptom checkers as national triage tools: an international case comparison study. BMJ. 30.9.2021. extension://elhekieabhbkpmcefcoobjddigjcaadp/https://informatics.bmj.com/content/bmjhci/28/1/e100448.full.pdf
COVID-19 Tutkimuskatsaus 11/2021. Koronakriisiin liittyviä ajankohtaisia tutkimustuloksia maailmalta ja Suomesta. Valtioneuvosto. 30.9.2021. https://julkaisut.valtioneuvosto.fi/bitstream/handle/10024/163530/COVID-19-tutkimuskatsaus%2011-2021.pdf?sequence=1&isAllowed=y
What are the long-term effects of COVID-19?
What we know
Mild and moderate cases
Severe cases
Mental health
Treatment and support
Chronic fatigue syndrome
When to seek help
Summary
Most people who develop coronavirus disease 19 (COVID-19) recover within 2–6 weeks, but some experience lasting symptoms. Others with severe COVID-19 may develop complications, require rehabilitation after a hospital stay, or both. Medical News Today. 29.9.2021. https://www.medicalnewstoday.com/articles/long-term-effects-of-coronavirus?utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=MNT%20Daily%20News&utm_content=2021-11-06&apid=32395010&rvid=348b31007bc4905a3c503d64d5572c0dac87e7263eba83389e708a2774ce1afc
DNA vs. mRNA vaccines: Similarities and differences
DNA and RNA vaccines use genetic material to deliver information to human cells and elicit an immune response. DNA vaccines are safe, easy, affordable to produce, and, unlike RNA vaccines, are stable at room temperature. These attributes make them more promising for rapidly immunizing populations, especially in resource-limited settings. Medical News Today. 28.9.2021. https://www.medicalnewstoday.com/articles/dna-vs-mrna-vaccines-similarities-and-differences?utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=MNT%20Daily%20News&utm_content=2021-11-06&apid=32395010&rvid=348b31007bc4905a3c503d64d5572c0dac87e7263eba83389e708a2774ce1afc
Evolving phenotypes of non-hospitalized patients that indicate long COVID. BMC Medicine. 27.9.2021. https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-021-02115-0
Yhdysvaltalaistutkimus: Näin koulujen maskipakko suojasi lapsia koronavirukselta. Yhdysvaltain tautikeskus CDC julkaisi perjantaina kaksi tutkimusta, jotka käsittelevät maskien käyttöä kouluissa. IS. 25.9.2021. https://www.is.fi/ulkomaat/art-2000008288977.html
U.S. schools with mask requirements are seeing fewer outbreaks, the C.D.C. finds. NYT. 24.9.2021. https://www.nytimes.com/2021/09/24/health/schools-mask-mandate-outbreaks-cdc.html?smtyp=cur&smid=fb-nytimes
Association Between K-12 School Mask Policies and School-Associated COVID-19 Outbreaks – Maricopa and Pima Counties, Arizona, June-August 2021. CDC. Morbidity and Mortality Weekly Report (MMWR). 24.9.2021. https://www.cdc.gov/mmwr/volumes/70/wr/mm7039e1.htm
Pediatric COVID-19 Cases in Counties With and Without School Mask
Requirements — United States, July 1–September 4, 2021. CDC. Morbidity and Mortality Weekly Report (MMWR). 24.9.2021. https://www.cdc.gov/mmwr/volumes/70/wr/mm7039e3.htm
New ease of measures announced: The new rules were announced on 23 September by the Prime Minister, António Costa, at the end of the Ministers meeting in which it was decided that Portugal will enter in the third and last phase of the ease of lockdown plan approved on 29 July. Find out everything you need to know about the new measures. The Portugal News. 23.9.2021. https://www.theportugalnews.com/news/2021-09-23/new-ease-of-measures-announced/62580
Epidemia COVID-19. Aggiornamento nazionale 22 settembre 2021 – ore 12:00. ISS. 24.9.2021. https://www.epicentro.iss.it/coronavirus/bollettino/Bollettino-sorveglianza-integrata-COVID-19_22-settembre-2021.pdf
SARS-CoV-2 infection causes immunodeficiency in recovered patients by downregulating CD19 expression in B cells via enhancing B-cell metabolism. Nature. 22.9.2021. https://www.nature.com/articles/s41392-021-00749-3
New Zealand growth in Q2 2021 confirms the Zero-Covid strategy outperforms the mitigation strategy of the G10 countries: 44 times less deaths, pre-crisis GDP exceeded, mobility and daily freedoms better preserved. Institut Economique Molinari. 21.9.2021. https://www.institutmolinari.org/2021/09/21/new-zealand-growth-in-q2-2021-confirms-the-zero-covid-strategy-outperforms-the-mitigation-strategy-of-the-g10-countries-44-times-less-deaths-pre-crisis-gdp-exceeded-mobility-and-daily-freedoms-bett/
On the effect of COVID-19 pandemic in the excess of human mortality. The case of Brazil and Spain. PLOS One. 2.9.2021. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0255909
September 21-30
Coronaviruses with a SARS-CoV-2-like receptor-binding domain allowing ACE2-mediated entry into human cells isolated from bats of Indochinese peninsula. ResearchSquare. 17.9.2021. https://www.researchsquare.com/article/rs-871965/v1
Post-COVID Conditions. CDC.16.9.2021. https://www.cdc.gov/coronavirus/2019-ncov/long-term-effects/index.html
EXCLUSIVE WHO-backed vaccine hub for Africa to copy Moderna COVID-19 shot. Reuters. 15.9.2021. https://www.reuters.com/world/africa/exclusive-who-backed-vaccine-hub-africa-copy-moderna-covid-19-shot-2021-09-14/
Successful control of COVID-19 outbreak through tracing, testing, and isolation: Lessons learned from the outbreak control efforts made in a metropolitan city of South Korea. Journal of Infection and Public Health. nn.9.2021. https://www.sciencedirect.com/science/article/pii/S1876034121001908
Why are Covid vaccine boosters needed and who in the UK will receive them?
Britain is joining nine other countries that have announced similar programmes offering an additional jab. FT. 14.9.2021. https://www.ft.com/content/cf83b3a1-fe06-4c9f-999c-7500090aee7c
11% of Israeli kids who got virus now suffer from ‘long COVID’ – study. Health Ministry survey finds 30% of those with long-term effects have cognitive, mental health issues, but cautions these can also be attributed to lockdowns, school closures, war. The Times of Israel. 14.9.2021. https://www.timesofisrael.com/more-than-10-of-israeli-kids-who-got-virus-now-suffer-from-long-covid-study/
Covid-19 and the new merchants of doubt. How best can scientists push back against science denialist campaigns? David Gorski and Gavin Yamey suggest some evidence based strategies. BMJ. 13.9.2021. https://blogs.bmj.com/bmj/2021/09/13/covid-19-and-the-new-merchants-of-doubt/
Genetic emergence of B.1.617.2 in COVID-19. New Microbes and New Infections NN.9.2021. https://www.sciencedirect.com/science/article/pii/S2052297521000937
September 11-20
Kommentti: Kuka jatkossa saa hoitoa? STM:n tuleva kansliapäällikkö sanoi sen, mitä muut eivät uskalla. Kirsi Varhila ansaitsee kiitosta rohkeudestaan. Hän nosti esiin asian, joka on poliittisesti tulenarka ja siksi siitä ollaan hiljaa, kirjoittaa erikoistoimittaja Heidi Hagelin. IS. 10.9.2021. https://www.is.fi/kotimaa/art-2000006234237.html
Keskustelun koronatesteistä tulee perustua tutkimusnäyttöön
Pikatestit löytävät koronavirusta tartuttavat yksilöt paremmin kuin Suomessa on ymmärretty. Kuka tartutti kenet -strategiasta voitaisiin siirtyä tartuntojen ennaltaehkäisyyn. Lääkärilehti. 8.9.2021. https://www.laakarilehti.fi/ajassa/verkkokommentti/keskustelun-koronatesteista-tulee-perustua-tutkimusnayttoon/?
Toimintasuunnitelma COVID-19 -epidemian hillinnän hybridistrategian toteuttamiseksi 2021-22. Luonnos 6.9.2021. VNK. https://vnk.fi/documents/10616/25232448/Hybridistrategian+toimintasuunnitelma+4.0.+luonnos+6.9.2021.pdf/446884d4-13d4-68c4-fa25-9b684940aa04/Hybridistrategian+toimintasuunnitelma+4.0.+luonnos+6.9.2021.pdf?t=1630944929454
THL:n Salminen: Pandemian loppusuora häämöttää – paluuta koviin rajoituksiin tuskin tullaan näkemään. THL:n Mika Salmisen mukaan rokotekattavuus on nyt tärkein epidemiatilanteesta kertova mittari, ja päivittäisten koronalukujen raportoinnista voitaisiin jo luopua. Paluu normaaliin häämöttää jo, sillä ensi viikolla Suomeen on tullut riittävästi rokotteita 80 prosentin rokotekattavuuden saavuttamiseksi. YLE. 5.9.2021. https://yle.fi/uutiset/3-12085688
Total Anti-SARS-CoV-2 Antibodies Measured 6 Months After Pfizer-BioNTech COVID-19 Vaccination in Healthcare Workers. SSRN. 3.9.2021. https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3915349
Downsides of face masks and possible mitigation strategies: a systematic review and meta-analysis. BMJ Open. 2.9.2022. https://bmjopen.bmj.com/content/11/2/e044364.info
Has Covid ended the neoliberal era? The year 2020 exposed the risks and weaknesses of the market-driven global system like never before. It’s hard to avoid the sense that a turning point has been reached. Guardian. 2.9.2021. https://www.theguardian.com/news/2021/sep/02/covid-and-the-crisis-of-neoliberalism
Risk factors and disease profile of post-vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: a prospective, community-based, nested, case-control study. @IanRicksecker … finding contradicts the findings from the UK Zoe app study, which found that “the odds of having symptoms for 28 days or more after post-vaccination infection were approximately halved by having two vaccine doses.” LANCET Infectious Diseases. 1.9.2021. https://doi.org/10.1016/S1473-3099(21)00460-6
September 1-10
Airborne transmission of respiratory viruses. Science . 27.8.2021. https://doi.org/10.1126/science.abd9149
SARS-CoV-2 infection of the central nervous system in a 14-month-old child: A case report of a complete autopsy. @IanRicksecker, An autopsy of a 14-month-old at Brazil’s Federal University of Rio de Janeiro found that “The brain exhibited severe atrophy and neuronal loss.” Lancet Regional Health Americas. 27.8.2021. https://doi.org/10.1016/j.lana.2021.100046
When it comes to staff safety during the pandemic, the buck stops with chief executives. One of the main preventive roles of occupational health experts in the pandemic is, or should have been, to advise and support managers/employers in risk management and control both as regards compliance with legal duties on health and safety. HSJ Wilmington Healthcare. 24.8.2021. https://www.hsj.co.uk/policy-and-regulation/when-it-comes-to-staff-safety-during-the-pandemic-the-buck-stops-with-chief-executives/7030773.article
Using test positivity and reported case rates to estimate state-level COVID-19 prevalence
and seroprevalence in the United States. PLOS Comp Biol. 23.8.2021. https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1009374&type=printable
Seroconversion and fever are dose-dependent in a nonhuman primate model of inhalational COVID-19. PLOS Pathogens. 23.8.2021. https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1009865
A microscopic video shows the coronavirus on the rampage. @IanRicksecker, And, yes, syncytia formation can happen in neurons. For our visual learners, here is video of syncytia and apoptosis (cell death) in a (bat) brain: NYT. 22.8.2021. https://www.nytimes.com/2021/08/22/science/microscopic-bat-brain-virus.html?smid=tw-nytimes&smtyp=cur
Persistent clotting protein pathology in Long COVID/Post-Acute Sequelae of COVID-19 (PASC) is accompanied by increased levels of antiplasmin. Cardiovascular Diabetology. 23.8.2021. https://cardiab.biomedcentral.com/articles/10.1186/s12933-021-01359-7
COVID-19-associated hyperinflammation and escalation of patient care: a retrospective longitudinal cohort study. Lancet. 21.8.2021 https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(20)30275-7/fulltext
August 21 – 31
Perspective. The Covid-19 Infodemic — Applying the Epidemiologic Model to Counter Misinformation. NEJM. 19.8.2021. https://www.nejm.org/doi/full/10.1056/NEJMp2103798
Similar patterns of [18F]-FDG brain PET hypometabolism in paediatric and adult patients with long COVID: a paediatric case series. European Journal of Nuclear Medicine and Molecular Imaging. 19.8.2021. https://link.springer.com/article/10.1007/s00259-021-05528-4
Brain imaging before and after COVID-19 in UK Biobank. @IanRicksecker, The UK Biobank COVID-19 re-imaging study compared before and after images of “mild” cases, and found “pronounced reduction in grey matter” and an “increase of diffusion indices, a marker of tissue damage” in specific regions of the brain. medRxiv. 18.8.2021. https://doi.org/10.1101/2021.06.11.21258690
Japan extends COVID-19 emergency lockdown as cases surge. Reuters. 18.8.2021. https://www.reuters.com/world/asia-pacific/japan-set-extend-covid-19-state-emergency-lockdown-sept-12-2021-08-17/
How COVID-19 vaccine supply chains emerged in the midst of a pandemic. PIIE. nn.8.2021. https://www.piie.com/publications/working-papers/how-covid-19-vaccine-supply-chains-emerged-midst-pandemic?
Infectious SARS-CoV-2 in Exhaled Aerosols and Efficacy of Masks During Early Mild Infection. medRxiv. 13.8.2021. https://www.medrxiv.org/content/10.1101/2021.08.13.21261989v1.full.pdf
The Vaccine Scientist Spreading Vaccine Misinformation. Robert Malone claims to have invented mRNA technology. Why is he trying so hard to undermine its use? Atlantic. 12.8.2021. https://www.theatlantic.com/science/archive/2021/08/robert-malone-vaccine-inventor-vaccine-skeptic/619734/
Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant. NEJM. 12.8.2021. https://www.nejm.org/doi/full/10.1056/NEJMoa2108891
A molecular test based on RT-LAMP for rapid, sensitive and inexpensive colorimetric detection of SARS-CoV-2 in clinical samples. Scientific Reports. 12.8.2021. https://www.nature.com/articles/s41598-021-95799-6
Impact of the COVID-19 Pandemic on Early Child Cognitive Development: Initial Findings in a Longitudinal Observational Study of Child Healt. medRxiv. 11.8.2021. https://www.medrxiv.org/content/10.1101/2021.08.10.21261846v1.full.pdf
Persistent Exertional Intolerance After COVID-19. Insights From Invasive Cardiopulmonary Exercise Testing. @IanRicksecker These patients are struggling with real physical issues. This Yale study demonstrated reduced aerobic capacity, oxygen extraction. and ventilatory efficiency in “mild” COVID patients even after recovery from their acute infection. CHEST Journal. 10.8.2021. https://doi.org/10.1016/j.chest.2021.08.010
August 11 – 20
We Studied One Million Students. This Is What We Learned About Masking. New York Times. 10.8.2021. https://www.nytimes.com/2021/08/10/opinion/covid-schools-masks.html
Moderna may be superior to Pfizer against Delta; breakthrough odds rise with time. Reuters. 9.8.2021. https://www.reuters.com/business/healthcare-pharmaceuticals/moderna-may-be-superior-pfizer-against-delta-breakthrough-odds-rise-with-time-2021-08-09/
KOTIMAA
Laumasuojateoria romahti, Suomessa suhde maskeihin mullistui yhdessä kesässä – näin tieto koronasta on muuttunut . Kiinan Wuhanista vuoden 2019 lopulla levinneeseen virukseen on liitetty useita harhaluuloja. Ilta=sanomat. 8.8.2021. https://www.is.fi/kotimaa/art-2000008179086.html
Viral infection and transmission in a large well-traced outbreak caused by the Delta SARS-CoV-2 variant. 7.8.2021. https://virological.org/t/viral-infection-and-transmission-in-a-large-well-traced-outbreak-caused-by-the-delta-sars-cov-2-variant/724
Pediatricians plead with FDA to move quickly on Covid vaccine for kids
”The delta variant has created a new and pressing risk to children and adolescents across this country,” president of the leading pediatricians group wrote. NBC News. 7.8.2021. https://www.nbcnews.com/health/health-news/pediatricians-plead-fda-move-quickly-covid-vaccine-kids-n1276191
The Pandemic Will End The Only Way It Can — The Hard Way. We still haven’t learned. Medium. 7.8.2021. https://jessicalexicus.medium.com/the-pandemic-will-end-the-only-way-it-can-the-hard-way-9770f003da9
Viral Load of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Respiratory Aerosols Emitted by Patients With Coronavirus Disease 2019 (COVID-19) While Breathing, Talking, and Singing. Clinical Infectious Diseases. 6.8.2021. https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciab691/6343417
Worauf warten Sie noch? Das ausgebuchte Impfzentrum ist keine Ausrede mehr – Ihre Hausärztin müsste längst Impfstoff für Sie haben. Zehn Gründe, mit der Corona-Impfung nicht länger zu warten. Zeit OnLine. 5.8.2021. https://www.zeit.de/gesundheit/2021-08/corona-impfung-nebenwirkungen-delta-variante-zweitimpfung-wirksam
Prevalence of ongoing symptoms following coronavirus (COVID-19) infection in the UK: 1 July 2021. ONS. 5.8.2021. https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/prevalenceofongoingsymptomsfollowingcoronaviruscovid19infectionintheuk/1july2021
Reduced neutralization of SARS-CoV-2 B.1.617 by vaccine and convalescent serum. Cell. 5.8.2021. https://www.sciencedirect.com/science/article/pii/S0092867421007558
Post-acute sequelae of COVID-19 in a non-hospitalized cohort: Results from the Arizona CoVHORT. @IanRicksecker The CoVHORT study, limited to non-hospitalized patients in Arizona – “mild” cases – found a 68% prevalence of 1 or more Covid symptom after 30 days, rising to 77% after 60 days. PLOS ONE. 4.8.2021. https://doi.org/10.1371/journal.pone.0254347
Where will you need a covid passport? Proof of vaccination or recovery from infection is increasingly being demanded, not just for international travel but also within countries. Economist. 4.8.2021. https://www.economist.com/the-economist-explains/2021/08/04/where-will-you-need-a-covid-passport
Asiantuntija penää selkeää linjaa: Mikä on ”riittävä rokotekattavuus” ja ”hyväksyttävä määrä” tartuntoja? Virustutkija Tuomas Aivelon mukaan kukaan ei tunnu tietävän, millainen rokotekattavuus olisi riittävä. Iltalehti. 4.8.2021. https://www.iltalehti.fi/koronavirus/a/098c101b-3a8d-467e-929e-5b590d0d7a13
Wuhan back in spotlight as China’s Delta variant challenge grows
China reports 328 locally transmitted cases in July — equal to previous five months’ total. AA. 3.8.2021. https://www.aa.com.tr/en/asia-pacific/wuhan-back-in-spotlight-as-chinas-delta-variant-challenge-grows/2322769
The association of opening K–12 schools with the spread of COVID-19 in the United States: County-level panel data analysis. PNAS. 3.8.2021. https://www.pnas.org/content/118/42/e2103420118
THL:n Mika Salmisen arvio: Tällainen on Suomen uusi koronastrategia. Suomen uusi koronastrategia saattaa muistuttaa aiemmin käytössä ollutta hybridimallia, mutta luvassa on myös merkittäviä muutoksia aiempaan. Ilta=sanomat. 3.8.2021. https://www.is.fi/kotimaa/art-2000008165493.html
Lapsiasiavaltuutettu vaatii kouluihin muutoksia koronan takia: ”Herkästi tarttuvat virusmuunnokset herättävät pelkoa”. Moitteita saa myös muun muassa lapsille ja nuorille suunnattu viestintä. Ilta=sanomat. 3.8.2021. https://www.is.fi/kotimaa/art-2000008167789.html
Kainuun sote testasi 74 ulkomaalaisen marjanpoimijan ryhmän: tartuntoja löytyi 44
Ulkomaalaisten marjanpoimijoiden ryhmässä 44 koronatartuntaa Kainuussa. Iltalehti. 3.8.2021. https://www.iltalehti.fi/kotimaa/a/93b675fe-7cf4-4274-9123-e3dbf4b51f29
Text-message nudges encourage COVID vaccination. A field trial shows that text-message ‘nudges’ encourage people to get vaccinated against COVID-19. To be effective, nudge approaches such as this must combine three aspects: they must prompt, enable and motivate behaviour. Nature. 2.8.2021. https://www.nature.com/articles/d41586-021-02043-2
Delta infections among vaccinated likely contagious; Lambda variant shows vaccine resistance in lab. Reuters. 2.8.2021. https://www.reuters.com/business/healthcare-pharmaceuticals/delta-infections-among-vaccinated-likely-contagious-lambda-variant-shows-vaccine-2021-08-02/
Suojaako jo yksi rokote pitkittyneeltä koronalta? Asiantuntijat vastaavat. Long covidin eli pitkittyneen koronan mahdollisuus mietityttää monia. Asiantuntijat kertovat, mitä nyt tiedetään rokotteiden tehosta sitä vastaan. Iltalehti. 2.8.2021. https://www.iltalehti.fi/terveysuutiset/a/b1367256-1f2f-4339-b722-7f45ec57ebb8
Microbiologist Elisabeth Bik queried Covid research – that’s when the abuse and trolling began. Bik’s home address was posted on Twitter and she faced a barrage of attacks after dissecting a paper endorsing hydroxychloroquine as treatment. Guardian. 2.8.2021. https://www.theguardian.com/science/2021/aug/03/microbiologist-elisabeth-bik-queried-covid-research-thats-when-the-abuse-and-trolling-began?CMP=Share_iOSApp_Other
Lääkärit huolissaan koulujen alkamisen riskeistä: ”Oppivelvollisten sairastuttaminen olisi vastuutonta ja typerää”. Uusi Suomi. 1.8.2021. https://www.uusisuomi.fi/uutiset/laakarit-huolissaan-koulujen-alkamisen-riskeista-oppivelvollisten-sairastuttaminen-olisi-vastuutonta-ja-typeraa/f79f22cc-4e0e-4233-b504-e31130247c8b
Brittiasiantuntijat varoittavat: Englannin puolittuneet koronatartunnat eivät välttämättä kerro todellisesta tilanteesta – tässä syy. mtv-uutiset. 1.8.2021. https://www.mtvuutiset.fi/artikkeli/brittiasiantuntijat-varoittavat-englannin-puolittuneet-koronatartunnat-eivat-valttamatta-kerro-todellisesta-tilanteesta-tassa-syy/8202752
Florida, COVID-19 epicentre in the U.S., breaks record with more than 21,000 new cases.
Sunshine State accounts for about a fifth of all new coronavirus cases in the country. CBC News. 1.8.2021. https://www.cbc.ca/news/world/florida-daily-cases-covid19-1.6125757
Nyssessä ei toistaiseksi oteta maskipakkoa uudestaan käyttöön – poistettiin juuri ennen kuin tartuntatapaukset alkoivat jyrkästi nousta: ”Ajoitus ei ollut täydellinen”
Maskipakkoa ei oteta uudestaan käyttöön, koska sen teho ei olisi enää yhtä suuri kuin aiemmin. Aamulehti. 1.8.2021. https://www.aamulehti.fi/koronavirus/art-2000008164627.html
Mask Mandates Save Lives. IMF Working Paper WP/21/205 nn.8.2021https://www.elibrary.imf.org/downloadpdf/journals/001/2021/205/001.2021.issue-205-en.pdf
What is the newly found COVID-19 ’Epsilon variant’ in Pakistan? – Details inside
New Epsilon variant found in Pakistan in its fourth wave amid the surge of COVID-19 cases.DNA India. 2.8.2021. https://www.dnaindia.com/science/report-what-is-the-newly-found-covid19-epsilon-variant-in-pakistan-details-inside-covid19-new-variant-coronavirus-new-variant-epsilon-variant-pakistan-lahore-california-4th-wave-coronavirus-news-alerts-latest-updates-2903645
In Provincetown 14 friends nab covid in a show of Delta’s might. Bloomberg. 1.8.2021. https://www.bloomberg.com/news/articles/2021-08-01/in-provincetown-14-friends-nab-covid-in-show-of-delta-s-might
Miten Suomi päätti voittaa koronan. Adlibris. 1.8.2021. https://www.adlibris.com/fi/kirja/miten-suomi-paatti-voittaa-koronan-9789523515178
August 1-10
Miksi korona ei ryöpsähdä Afrikassa? Viisi koronamysteeriä, jotka ovat vailla vastauksia
Tartuntatautien tutkimuskeskuksen johtajan mukaan virus ei ole levinnyt odotetusti. ILtalehti. 31.7.2021. https://www.iltalehti.fi/ulkomaat/a/21ac0b79-08d7-49a1-a76b-c9879e8053fd
Porilaistaustainen erikoislääkäri Maria Juusela pitää ministereiden lähikoulupuhetta edesvastuuttomana – lapset etäkouluun ja kaikki rokotuksiin: ”Kuka ottaa vastuun, jos vanhempi kieltää lapselta koronarokotteen ja tämä sairastuu vakavasti?
Keuhkosairauksiin erikoistunut erikoislääkäri Maria Juusela varoittaa koronarokotusten viivyttelystä, sillä nuorten ja rokottamattomien osuus sairaalahoidossa kasvaa. Nuoria on jo nyt tehohoidossa ja puolet lievänkin koronan saaneista nuorista kärsii tutkimusten mukaan long covid -oireista. Satakunnan Kansa. 31.7.2021. https://www.satakunnankansa.fi/satakunta/art-2000008157559.html
Yli 20 uutta tartuntaa rippileirillä levinneestä koronaryppäästä – altistuneiden määrää lähes mahdoton arvioida. Koronavirus ehti levitä rippileirillä tehokkaasti. Lääkäri epäilee, että lähes kaikki leirille osallistuneet ovat voineet sairastua. YLE-Uutiset. 31.7.2021. https://yle.fi/uutiset/3-12042355
”FFP2-suojain on ainoa tapa, jolla omaa turvallisuuttaan voi parantaa” – Deltavariantti leviää helposti myös ulkona, asiantuntija kertoo, miten se on syytä huomioida
Deltavariantti tarttuu aiempia variantteja herkemmin myös ulkotiloissa. Asiantuntija neuvoo hyödyntämään tupakansavusääntöä ja käyttämään maskia, jos etäisyyttä ei voi pitää. Helsingin Sanomat. 31.7.2021. https://www.hs.fi/hyvinvointi/art-2000008161774.html
Evidence of lung perfusion defects and ongoing inflammation in an adolescent with post-acute sequelae of SARS-CoV-2 infection. Lancet. 30.7.2021. https://www.thelancet.com/pdfs/journals/lanchi/PIIS2352-4642(21)00196-6.pdf
CDC document warns Delta variant appears to spread as easily as chickenpox and cause more severe infection. CNN Politics. 30.7.2021. https://edition.cnn.com/2021/07/29/politics/cdc-masks-covid-19-infections/index.html
Vaccinated People May Spread the Virus, Though Rarely, C.D.C. Reports
The agency cited an outbreak in Provincetown, Mass., in which most of the infected were immunized. An internal C.D.C. document paints an even more harrowing picture. New York Times. 30.7.2021. https://www.nytimes.com/2021/07/30/health/cdc-vaccinated-delta.html
FFP3 masks: study shows they significantly reduce the risk of COVID-19 infection. Royal College of Nursing. 29.7.2021. https://www.rcn.org.uk/news-and-events/news/uk-ffp3-masks-study-shows-they-significantly-reduce-the-risk-of-covid-19-infection-290621
COVID-19 ASSOCIATED WITH LONG-TERM COGNITIVE DYSFUNCTION, ACCELERATION OF ALZHEIMER’S SYMPTOMS. AAIC 21. 29.7.2021. https://www.alz.org/aaic/downloads2021/COVID-19_and_Long-Term_Cognitive_Dysfunction.pdf
Covid-19 linked to cognitive decline, acceleration of Alzheimer’s-like symptoms, research finds. CNN Heakth. 29.7.2021. https://edition.cnn.com/2021/07/29/health/covid-cognitive-decline-alzheimers/index.html
An outbreak caused by the SARS-CoV-2 Delta variant (B.1.617.2) in a secondary care hospital in Finland, May 2021. Eurosurveilance. 29.7.2021. https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2021.26.30.2100636
A look into the future of the COVID-19 pandemic in Europe: an expert consultation. Lancet Regional Health for Europe. 29.7.2021. https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(21)00162-9/fulltext
New study finds COVID-19 can cause changes in brain that mimic Alzheimer’s disease. FOX9. 29.7.2021. https://web.archive.org/web/20210730041354/https://www.fox9.com/news/new-study-finds-covid-19-can-cause-changes-in-brain-that-mimics-alzheimers-disease
SARS-CoV-2 Lambda variant exhibits higher infectivity and immune resistance. bioRxiv. 28.7.2021. https://www.biorxiv.org/content/10.1101/2021.07.28.454085v1
Israeli hospitals reopen their coronavirus wards as serious cases mount
Number of serious patients reaches 153, having more than doubled in a week, Health Ministry data shows. The Times of Israel. 28.7.2021. https://www.timesofisrael.com/israeli-hospitals-reopen-their-coronavirus-wards-as-serious-cases-mount/
Texas doctor warns COVID-19 cases are rising among children. Some are on ventilators. The Hill. 28.7.2021. https://thehill.com/changing-america/well-being/longevity/565323-texas-doctor-warns-covid-cases-are-rising-among
Hoitoalalla työskentelevä nainen järkyttyi Tikkurila Festivaalilla – Turvaväleistä ei puhettakaan, maskeja ei yleisössä kellään. Vantaan Sanomat. 27.7.2021. https://www.vantaansanomat.fi/paikalliset/4235633
COVID-19 false dichotomies and a comprehensive review of the evidence regarding public health, COVID-19 symptomatology, SARS-CoV-2 transmission, mask wearing, and reinfection. @IanRicksecker It’s even good for the economy: ”Globally, economic contraction and growth closely mirror increases and decreases in COVID-19 cases… Public health strategies that reduce SARS-CoV-2 transmission also safeguard the economy.” BMC Infectious Diseases. 27.7.2021. https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-021-06357-4
COVID-19-infektioon liittyvä lasten hyperinflammatorinen oireyhtymä. Duodecim. 27.7.2021. https://www.duodecimlehti.fi/duo15880
UPDATE week to 26-July. Childhood COVID, England. @jneill. 26.7.2021. https://twitter.com/jneill/status/1419697733632471047?s=12
Long COVID cases among children and pediatric death toll rise globally. World Socialist Web Site. 26.7.2021. https://www.wsws.org/en/articles/2021/07/27/long-j27.html
Biden says ’long COVID’ patients could qualify for having disability. UPI. 26.10.2021. https://www.upi.com/Top_News/US/2021/07/26/bs-us-long-covid-disability-biden/1031627316110/
Doctors Worry That Memory Problems After COVID-19 May Set The Stage For Alzheimer’s. NPR. 26.7.2021. https://www.npr.org/sections/health-shots/2021/07/26/1019875347/doctors-worry-that-memory-problems-after-covid-19-may-set-stage-for-alzheimers?t=1644221638372
COVID-19 linked to ’substantial’ drop in intelligence, new research finds
People who had been hospitalised and put on a ventilator saw the biggest deficit in the Great British Intelligence Test – equivalent to a seven-point drop in IQ. Sky news. (Long COVID) 26.7.2021. https://news.sky.com/story/covid-19-linked-to-substantial-drop-in-intelligence-new-research-finds-12364433
The mystery of COVID-19 reinfections: A global systematic review and meta-analysis of 577 cases. medRxiv. 25.7.2021. https://www.medrxiv.org/content/10.1101/2021.07.22.21260972v2.full.pdf
Falling off the cliff: Mythical sacrifice mirrored in Sweden’s COVID-19 response. AAGE. 23.7.2021. http://anthropologyandgerontology.com/falling-off-the-cliff-mythical-sacrifice-mirrored-in-swedens-covid-19-response/
SARS-COV-2 Delta variant now dominant in much of the European Region and efforts must be reinforced to prevent transmission, warn WHO/Europe and ECDC. ECDC. 23.7.2021. https://www.ecdc.europa.eu/en/news-events/sars-cov-2-delta-variant-now-dominant-european-region
Cognitive deficits in people who have recovered from COVID-19. @IanRicksecker, That seems to explain why there is evidence of persistent cognitive deficits in people who have recovered from SARS-CoV2 infection in Great Britain. EClinicakMedicine. 22.7.2021. https://doi.org/10.1016/j.eclinm.2021.101044
Short Report on Long COVID. This report is provided at the request of SAGE and includes information from ongoing studies investigating long COVID including the COVID-19 Longitudinal Health and Wellbeing National Core. Study-CONVALESCENCE Study, REACT-2, PHOSP-COVID, ONS’s COVID-19 Infection Survey (CIS) and the COVID Symptom Study App. ONS. 22.7.2021. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1007511/S1327_Short_Long_COVID_report.pdf
Hospital length of stay for COVID-19 patients: Data-driven methods for forward planning. BMC Infectious Diseases. 22.7.2022. https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-021-06371-6
We’re Zeroing In On the ‘Holy Grail’ of COVID-19 Immunity. There’s no good way of measuring whether your vaccine worked—yet. Atlantic. 21.7.2021. https://www.theatlantic.com/science/archive/2021/07/correlates-of-protection-vaccine-immunity/619508/
CDC 2019-Novel Coronavirus (2019-nCoV) Real-Time RT-PCR Diagnostic Panel For Emergency Use Only:Instructions for Use. 21.7.2021. https://www.fda.gov/media/134922/download
Cognitive deficits in people who have recovered from COVID-19. Lancet. 21.7.2021. https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(21)00324-2/fulltext
July 21 – 31
FFP3 masks: study shows they significantly reduce the risk of COVID-19 infection. Royal College of Nursing. 29.7.2022. https://www.rcn.org.uk/news-and-events/news/uk-ffp3-masks-study-shows-they-significantly-reduce-the-risk-of-covid-19-infection-290621
Covid: ’Beware Of Epsilon Variant, Risk Of Infection Even For Immunised People’. Epsilon variant of Covid: only two cases, in Italy, already isolated. Emergency LIVE. 19.7.2021. https://www.emergency-live.com/news/covid-beware-of-epsilon-variant-risk-of-infection-even-for-immunised-people/
’Acute Covid’ spreading in young people can ’rip through their organs’, expert warns
Professor Calum Semple has warned that while they may not be at risk of death, young people could be ”damaged” by the devastating effects of acute Covid on their organs. Mirror. 15.7.2021. https://www.mirror.co.uk/news/uk-news/acute-covid-spreading-young-people-24539633?
Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents. JAMA Network. 15.8.2021. https://jamanetwork.com/journals/jama/fullarticle/2782164
Air pollution, racial disparities, and COVID-19 mortality. Journal of Allergy and Clinical Immunology. NN.7.2021. https://www.sciencedirect.com/science/article/pii/S0091674920306321
Presence of SARS-CoV-2 Aerosol in Residences of Adults with COVID-19. Annals of American Thoracic Society. nn.7.2021. https://www.atsjournals.org/doi/full/10.1513/AnnalsATS.202107-847RL
Kaikkien koronatartuntojen estäminen rajoituksilla on mahdotonta, sanoo THL:n Hanna Nohynek: ”Olemme kohta kuin Pohjois-Koreassa”
Emeritusprofessori Matti Jantunen on toista mieltä: hänestä rajoitusten purku olisi kuin sallisi humalassa ajamisen. Yhteiskunnan avaamisen aikataulu on arvokysymys. Suomen Kuvalehti. 14.7.2022. https://suomenkuvalehti.fi/kotimaa/kaikkien-koronatartuntojen-estaminen-rajoituksilla-on-mahdotonta-sanoo-thln-hanna-nohynek-olemme-kohta-kuin-pohjois-koreassa/
THL:n Salminen: ”Elämä palaa vanhoille raiteille” – lohduttava viesti suomalaisille
THL:n johtaja Mika Salmisen mukaan edessämme on paluu aivan normaaliin arkeemme, ei uuteen normaaliin. TERVEYS. 12.7.2021. https://www.iltalehti.fi/terveysuutiset/a/6e433208-821b-4dbc-b25a-6c9b1e4f0b02
OpenABM-Covid19—An agent-based model for non-pharmaceutical interventions against COVID-19 including contact tracing. PLOS. 12.7.2021. https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1009146
Coronavirus: Hong Kong study shows significant percentage of recovered patients struggle with memory loss, depression. South China Morning Post. 12.7.2021. https://sg.news.yahoo.com/coronavirus-hong-kong-study-shows-113844553.html?guccounter=1
July 11-20
NIH study associates COVID-19 surges with mortality increases for patients (Long COVID). NIH. 8.7.2021. https://www.nih.gov/news-events/news-releases/nih-study-associates-covid-19-surges-mortality-increases-patients
Warning of serious brain disorders in people with mild coronavirus symptoms. UK neurologists publish details of mildly affected or recovering Covid-19 patients with serious or potentially fatal brain conditions. Guardian. 8.7.2020. https://www.theguardian.com/world/2020/jul/08/warning-of-serious-brain-disorders-in-people-with-mild-covid-symptoms
A Tsunami of Disability Is Coming as a Result of ‘Long COVID’
We need to plan for a future where millions of survivors are chronically ill. Scientific American. 6.7.2021. https://www.scientificamerican.com/article/a-tsunami-of-disability-is-coming-as-a-result-of-lsquo-long-covid-rsquo/
7-1-7: an organising principle, target, and accountability metric to make the world safer from pandemics. Lancet. 6.7.2021. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)01250-2/fulltext
COVID and the brain: researchers zero in on how damage occurs. Growing evidence suggests that the coronavirus causes ‘brain fog’ and other neurological symptoms through multiple mechanisms. @IanRicksecker, If you’re interested in further understanding the host of neurological symptoms and the mechanisms underlying them, this Nature article is an excellent primer: Nature. 7.7.2021. https://www.nature.com/articles/d41586-021-01693-6
A Tsunami of Disability Is Coming as a Result of ‘Long COVID’. We need to plan for a future where millions of survivors are chronically ill. @IanRicksecker, Since our vaccines don’t stop transmission, and don’t appear to stop long-term illness, a “vaccination only” strategy is not going to be sufficient to prevent mass disability. This isn’t something we want to expose our kids to. Scientific American. 6.7.2021. https://www.scientificamerican.com/article/a-tsunami-of-disability-is-coming-as-a-result-of-lsquo-long-covid-rsquo/
Testicular pathology in fatal COVID-19: A descriptive autopsy study. @IanRicksecker, The brain isn’t the only organ affected: Testicular pathology has found evidence of “SARS-Cov-2 antigen in Leydig cells, Sertoli cells, spermatogonia, and fibroblasts” in post-morten examination. Andrology. 1.7.2021. https://doi.org/10.1111/andr.13073
July 1-10
COVID-19 and Human Rights. Routleg. 30.6.2021. https://www.routledge.com/COVID-19-and-Human-Rights/Kjaerum-Davis-Lyons/p/book/9780367688035#
Ivermectin for the Treatment of Coronavirus Disease 2019: A Systematic Review and Meta-analysis of Randomized Controlled Trials. IDSA 28.6.2021. https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciab591/6310839
Long COVID in a prospective cohort of home-isolated patients. @IanRicksecker Despite a different definition of “symptoms”, the Bergen study in Norway found that 61% of patients had symptoms after six months, including 52% of patients aged 16-30 years who had not been hospitalized. Nature Medicine. 23.6.2021. https://www.nature.com/articles/s41591-021-01433-3
Dysregulation of brain and choroid plexus cell types in severe COVID-19. @IanRicksecker A joint study by Stanford and Germany’s Saarland University found inflammation in the brain, and “show[ed] that peripheral T cells infiltrate the parenchyma.” Nature. 21.6.2021. https://www.nature.com/articles/s41586-021-03710-0
Longitudinal Assessment of Diagnostic Test Performance Over the Course of Acute SARS-CoV-2 Infection. IDSA. 20.6.2021. https://academic.oup.com/jid/article/224/6/976/6311835
Why are women more prone to long Covid? While men over 50 tend to suffer the most acute symptoms of coronavirus, women who get long Covid outnumber men by as much as four to one. Guardian. 13.6.2021. https://www.theguardian.com/society/2021/jun/13/why-are-women-more-prone-to-long-covid
Breathing, speaking, coughing or sneezing: What drives transmission of SARS-CoV-2? Journal of Internal Medicine. 8.6.2021. https://doi.org/10.1111/joim.13335
Probable airborne transmission of SARS-CoV-2 in a poorly ventilated restaurant. Building and Environment. NN.6.2021. https://www.sciencedirect.com/science/article/pii/S0360132321001955?via%3Dihub
Household COVID-19 risk and in-person schooling. Science. 4.6.2021. https://www.science.org/doi/10.1126/science.abh2939
June
Mask Use and Ventilation Improvements to Reduce COVID-19 Incidence in Elementary Schools — Georgia, November 16–December 11, 2020 []sisäilman sekoittamisella päästiin 35 prosenttia pienempään koronatartuntojen esiintyvyyteen ja yhdistettynä ilmanpuhdistuksen tehostamiseen 48 prosenttia pienempään esiintyvyyteen.. CDC-MMWR. 28.5.2021. https://www.cdc.gov/mmwr/volumes/70/wr/mm7021e1.htm
Face masks effectively limit the probability of SARS-CoV-2 transmission. Science. 20.5.2021. https://doi:10.1126/science.abg6296
A paradigm shift to combat indoor respiratory infection. Science. 14.5.2021. https://doi:10.1126/science.abg2025
The 60-Year-Old Scientific Screwup That Helped Covid Kill. All pandemic long, scientists brawled over how the virus spreads. Droplets! No, aerosols! At the heart of the fight was a teensy error with huge consequences. Wired. 13.5.2021. https://www.wired.com/story/the-teeny-tiny-scientific-screwup-that-helped-covid-kill/
COVID-19 está en el aire. Numeroteca. 13.5.2021. https://numeroteca.org/cat/en-el-aire/
Embracing the science on airborne transmission is key to preventing new COVID-19 outbreaks. The Globe and Mail. 10.5.2021. https://www.theglobeandmail.com/amp/opinion/article-embracing-the-science-on-airborne-transmission-is-key-to-preventing/?utm_medium=Referrer%3A%20Social%20Network%20%2F%20Media&utm_campaign=Shared%20Web%20Article%20Links&__twitter_impression=true
May
Severe COVID-19 in people with type 1 and type 2 diabetes in Sweden: A nationwide retrospective cohort study. Lancet. 30.4.2021. https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762%2821%2900082-X/fulltext
COVID-19 Indoor Safety Guideline. https://indoor-covid-safety.herokuapp.com/
A guideline to limit indoor airborne transmission of COVID-19. PNAS. 27.4.2021. https://doi.org/10.1073/pnas.2018995118
High-dimensional characterization of post-acute sequelae of COVID-19. Nature. 22.4.2021. https://pubmed.ncbi.nlm.nih.gov/33887749/
THE STUDY OF CO2 CONCENTRATION IN A CLASSROOM DURING THE COVID-19 SAFETY MEASURES. Cold Climate HVAC & Energy 2021. 20.4.2021. https://www.e3s-conferences.org/articles/e3sconf/pdf/2021/22/e3sconf_hvac2021_01004.pdf
Monitoring carbon dioxide to quantify the risk of indoor airborne transmission of COVID-19. MedRxiv. 16.4.2021. https://doi.org/10.1101/2021.04.04.21254903
REHVA COVID-19 guidance document. How to operate HVAC and other building service systems to prevent the spread of the coronavirus (SARS-CoV-2) disease (COVID-19) in workplaces. REHVA 15.4.2021. https://www.rehva.eu/activities/covid-19-guidance/rehva-covid-19-guidance
Ten scientific reasons in support of airborne transmission of SARS-CoV-2. Lancet. 15.4.2021. https://www.thelancet.com/article/S0140-6736(21)00869-2/fulltext
Tuore suomalaistutkimus: FFP-maski suojaa koronalta terveydenhuollossa
Väitöstutkija Lotta Oksanen suosittelee FFP-suojaimia työpisteisiin, joissa voi kohdata koronaan sairastuneen. Lääkärilehti. 12.4.2021. https://www.laakarilehti.fi/tieteessa/uutiset/tuore-suomalaistutkimus-ffp-maski-suojaa-koronalta-terveydenhuollossa/?public=1caddc5a00d9df8176df646517b3b546
Povidone Iodine (PVP-I) Oro-Nasal Spray: An Effective Shield for COVID-19 Protection for Health Care Worker (HCW), for all. Indian J Otolaryngol Head Neck Surg. 8.4.2021. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026810/
Risk assessment for airborne disease transmission by poly-pathogen aerosols. PLOS Onre. 8.4.2021. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0248004
6-month neurological and psychiatric outcomes in 236 379 survivors of COVID-19: a retrospective cohort study using electronic health records. Lancet Psychiatry. 6.4.2021. https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(21)00084-5/fulltext
Overdispersion in COVID-19 increases the effectiveness of limiting nonrepetitive contacts for transmission control. PNAS. 6.4.2021. https://www.pnas.org/content/118/14/e2016623118
Exhaled CO2 as a COVID-19 Infection Risk Proxy for Different Indoor Environments and Activities. (Jimenez) Environmental Science & Technology. 5.4.2021. https://doi.org/10.1021/acs.estlett.1c00183
SARS-CoV-2 and Surface (Fomite) Transmission for Indoor Community Environments. CDC. 5.4.2021. https://www.cdc.gov/coronavirus/2019-ncov/more/science-and-research/surface-transmission.html
April
Effects of SARS-CoV-2 infection on neuroimaging and neurobehavior in neonates. World J of Pediatrics. 19.3.2021. https://link.springer.com/article/10.1007/s12519-021-00423-2
Recurrent COVID-19 including evidence of reinfection and enhanced severity in thirty Brazilian healthcare workers. J Infection. 11.3.2021. https://www.journalofinfection.com/article/S0163-4453(21)00043-8/fulltext
School reopening without robust COVID-19 mitigation risks accelerating the pandemic. Lancet. 10.3.2021. https://www.thelancet.com/journals/lancet/article/PIIS0140-67362100622-X/fulltext
Long-term clinical, virological and immunological outcomes in patients hospitalized for COVID-19: antibody response predicts long COVID. medExiv. 8.3.2021. https://www.medrxiv.org/content/10.1101/2021.03.08.21253124v1.full
A guideline to limit indoor airborne transmission of COVID-19. PNAS. 3.3.2021. https://www.pnas.org/content/118/17/e2018995118
COVID-19 – exploring the implications of long-term condition type and extent of multimorbidity on years of life lost (YLL, UK, Italy): a modelling study. Wellcome Open Research. 1.3.2021. https://wellcomeopenresearch.org/articles/5-75
March
Adapting COVID-19 vaccines to SARS-CoV-2 variants: guidance for vaccine manufacturers Share. European Medicines Agency. 25.2.2021. https://www.ema.europa.eu/en/news/adapting-covid-19-vaccines-sars-cov-2-variants-guidance-vaccine-manufacturers
Market design to accelerate COVID-19 vaccine supply. Science. 25.2.2021. https://www.science.org/doi/10.1126/science.abg0889
Unmasking the mask studies: why the effectiveness of surgical masks in preventing
respiratory infections has been underestimated. aRxiv. 24.2.2021. https://arxiv.org/pdf/2102.04882.pdf
Outdoor Transmission of SARS-CoV-2 and Other Respiratory Viruses: A Systematic Review. J Infect Dis. 24.2.2021. https://pubmed.ncbi.nlm.nih.gov/33249484/
Karanteenin unohtava keskustelu perusoikeuksista koronanhallinnassa on nurinkurista. Thomas Bradd. 24.2.2021. https://thomasbrand.me/korona/karanteenin-unohtava-keskustelu-perusoikeuksista-koronanhallinnassa-on-nurinkurista
NIH launches new initiative to study “Long COVID”. NIH. 23.2.2021. https://www.nih.gov/about-nih/who-we-are/nih-director/statements/nih-launches-new-initiative-study-long-covid
Years of life lost to COVID-19 in 81 countries. Scientific Reports. 8.2.2021. https://www.nature.com/articles/s41598-021-83040-3
Sequelae in Adults at 6 Months After COVID-19 Infection. @IanRicksecker A University of Washington study found that 30% of Covid patients had reduced Health Related Quality of Life, with 8% of the patients limited in routine daily activities. JAMA. 19.2.2021. https://doi:10.1001/jamanetworkopen.2021.0830
Effectiveness of Mask Wearing to Control Community Spread of SARS-CoV-2. JAMA Network. 10.2.2021. https://jamanetwork.com/journals/jama/fullarticle/2776536?
Aerosol emission of adolescents voices during speaking, singing and shouting. PLOS ONE. 10.2.2021. https://doi.org/10.1371/journal.pone.0246819
Miksi Suomessa on päädytty 12 viikon rokotusväliin? Koronarokotteiden optimaalista annosväliä ei ole tutkittu, koska on pyritty mahdollisimman nopeaan ohjelmaan. Lääkärilehti. 10.2.2021. https://www.laakarilehti.fi/ajassa/ajankohtaista/miksi-suomessa-on-paadytty-12-viikon-rokotusvaliin/
Covid-19: Social murder, they wrote—elected, unaccountable, and unrepentant. BMJ. 4.2.2021. https://www.bmj.com/content/372/bmj.n314
February
Preliminary Evidence on Long COVID in children. @IanRicksecker Children also suffer from Long Covid. ”More than half [of pediatric patients] reported at least one persisting symptom even 120 days [after] COVID-19, with 42.6% impaired by these symptoms during daily activities.” medRxiv. 26.1.2021. https://doi.org/10.1101/2021.01.23.21250375
Undercounting of Covid-19 deaths is greatest in pro-Trump areas, analysis shows. STAT. 25.1.2021. https://www.statnews.com/2021/01/25/undercounting-covid-19-deaths-greatest-in-pro-trump-areas-analysis-shows/
How COVID-19 Spreads. CDC. 14.1.2021. https://www.cdc.gov/coronavirus/2019-ncov/prevent-getting-sick/how-covid-spreads.html
Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection. Nature Immunology. 13.1.2021. https://www.nature.com/articles/s41590-021-01113-x
What is the economic impact of the latest round of lockdowns? The rich world has become better at mitigating their economic cost. Economist. 13.1.2021. https://www.economist.com/finance-and-economics/2021/01/13/what-is-the-economic-impact-of-the-latest-round-of-lockdowns
Dismantling myths on the airborne transmission of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The Journal of Hospital Infection. 12.1.2021. https://www.journalofhospitalinfection.com/article/S0195-6701(21)00007-4/fulltext
An evidence review of face masks against COVID-19. PNAS 11.1.2021. https://www.pnas.org/doi/full/10.1073/pnas.2014564118
Muistio: Koronavirusmuunnosten leviäminen Suomessa on estettävä välittömästi. Eroonkoronasta. 10.1.2021. https://www.eroonkoronasta.fi/muistio-koronavirusmuunnosten-leviaeminen-suomessa-on-estettaevae-vaelittoemaesti/
Why facemasks were not recommended despite their benefits. Pasi Malm. 2021-01-02. https://www.researchgate.net/publication/348162827_Why_facemasks_were_not_recommended_despite_their_benefits_2021-01-02
A guide towards healthy classrooms. Michael Riedeker Blog. 6.1.2021. COVID-19 | SCOEH
January 2021
Akt-Fas to Quell Aberrant T Cell Differentiation and Apoptosis in Covid-19. @IanRicksecker, There are also immunology implications:Johns Hopkins’ @fitterhappierAJ found that “CD95-mediated [T cell] differentiation and death may be advancing T cells to greater effector acquisition, fewer numbers, and immune dysregulation.” Frontiers in immunology. 21.12.2020. https://doi.org/10.3389/fimmu.2020.600405
Face masks to prevent transmission of COVID-19: A systematic review and meta-analysis. Am J Infect Control. 19.12.2020. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7748970/
Filtration Efficiency of Face Masks Used by the Public During the COVID-19 Pandemic. JAMA Network. 19.12.2020. https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2774265
The S1 protein of SARS-CoV-2 crosses the blood-brain barrier in mice. @IanRicksecker, The virus appears to be able to cross the blood-brain barrier and cause significant neurological damage. The ability of the spike protein to cross the blood-brain barrier was demonstrated in mice at the University of Washington. Nature Neuroscience. 16.12.2020. https://doi:10.1038/s41593-020-00771-8
We want them infected’: Trump appointee demanded ‘herd immunity’ strategy, emails reveal. Then-HHS science adviser Paul Alexander called for millions of Americans to be infected as means of fighting Covid-19 [GBD, Children]. Politico. 16.12.2020. https://www.politico.com/news/2020/12/16/trump-appointee-demanded-herd-immunity-strategy-446408
Modeling epidemic spreading through public transit using time-varying encounter network. Transp Res Part C Emerg Tecnol. 15.12.2020. https://pubmed.ncbi.nlm.nih.gov/33519128/
The Culling: Pandemic, Gerocide, Generational Affect. Medical Anthropology Quarterly. 4.12.2020. https://anthrosource.onlinelibrary.wiley.com/doi/full/10.1111/maq.12627
FINCOVID-19. Tutkimus koronataudin pitkäaikaisvaikutuksista. FILHA. 4.12.2020. https://www.filha.fi/hankkeet/fincovid-19/
Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19. Nature neuroscience. 30.11.2020. https://www.nature.com/articles/s41593-020-00758-5
No evidence for increased transmissibility from recurrent mutations in SARS-CoV-2. Nature. 25.11.2020. https://www.nature.com/articles/s41467-020-19818-2
Evidence of Structural Protein Damage and Membrane Lipid Remodeling in Red Blood Cells from COVID-19 Patients. @IanRicksecker, It’s also a vascular disease. A Columbia study found ”significantly altered lipid metabolism” during acute disease, which ”suggests a significant impact of SARS-CoV-2 infection on red blood cell structural membrane homeostasis.” J Proteome Res. 19.11.2020. https://doi.org/10.1021/acs.jproteome.0c00606
Immunity to the Coronavirus May Last Years, New Data Hint. Blood samples from recovered patients suggest a powerful, long-lasting immune response, researchers reported. New York Times. 17.11.2022. https://www.nytimes.com/2020/11/17/health/coronavirus-immunity.html?referringSource=articleShare
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Hulluksi leimaamista, vähättelyä, tukien menetyksiä: pitkä korona voi viedä työkyvyn perusterveeltä ja potilaat vaativat nyt tiedotusta. Suomessa voi olla jo tuhansia potilaita, joiden kuukausien oireilu johtuu koronasta. Toisen aallon sairastajia ei ole laskettu lukuun. YLE-Uutiset. 28.10.2020. https://yle.fi/uutiset/3-11613115
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This Chinese military study of the initial Wuhan outbreak concluded that “T cell counts are reduced significantly in COVID-19 patients, and the surviving T cells appear functionally exhausted.” The study authors went on to warn, “Non-ICU patients with total T cells counts lower than 800/μL may still require urgent intervention, even in the immediate absence of more severe symptoms due to a high risk for further deterioration in condition.” Frontiers in Immunology. 1.5.2020. https://www.frontiersin.org/articles/10.3389/fimmu.2020.00827/full
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Osuus positiivisista COVID-19-testeistä. Vahvistettujen tapausten kokonaismäärä osuutena testattujen ihmisten kokonaismäärästä tai suoritettujen testien määrästä – sen mukaan, miten maa raportoi testitiedot. Luvut esitetään ajan mittaan viidennen vahvistetun kuoleman jälkeen kuluneiden päivien mukaan. https://ourworldindata.org/grapher/covid19-positive-rate-since-5th-death?time=2020-02-23 .. viimeisin
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