Constantly updated chronological collection of COVID-links. Vol 7.

Vol 7 korvaa täysin Vol 6:n. Linkit, joiden täydentäminen alkoi 7.2.2021. Uusimmat linkit ovat ylimpänä. Tämä nopeuttaa kiinnostavimpien, usein uusimpien linkkien löytämistä. Jatkuvasti päivittyvät löytyvät edelleen alimpana.

Disclaimer: Tästä ja edellisistä viidestä linkkikokoelmasta löytyvät artikkelit eivät muodosta täydellistä, edustavaa, suositeltua eikä luotettavaksi varmennettua koostetta eri medioissa julkaistuista SARS-CoV-2 virukseen, Covid-19 sairauteen, sen hoitoon tai estämiseen liittyvistä artikkeleista.

 

_________________________

Coronavirus World Map: Tracking the Global Outbreak. New York Times. Accessed 24.8.2022. https://www.nytimes.com/interactive/2021/world/covid-cases.html

Työsuojelun yhteistoiminta ja riskien arvioinnin päivitys on edelleen tärkeää.
Koulujen alettua myös erilaiset tartuntataudit ovat levinneet. OAJ muistuttaa, että korona edellyttää edelleen muun muassa riskien arviointia päiväkodeissa, kouluissa ja oppilaitoksissa. OAJ. 23.8.2022. https://www.oaj.fi/ajankohtaista/uutiset-ja-tiedotteet/2022/tyosuojelun-yhteistoiminta-ja-riskienarvioinnin-paivitys-on-edelleen-tarkeaa/

Ylilääkäri: Jos olet kipeä, sinulla on todennäköisesti korona. Verkkouutiset. 22.8.2022. https://www.verkkouutiset.fi/a/ylilaakari-jos-olet-kipea-sinulla-on-todennakoisesti-korona/#1debac39

Rates of COVID-19 Cases and Deaths by Vaccination Status. CDC COVID Data Tracker. Accessed 22.8.2022. https://covid.cdc.gov/covid-data-tracker/#rates-by-vaccine-status

Apinarokko. THL. Accessed 22.8.2022. https://thl.fi/fi/web/infektiotaudit-ja-rokotukset/taudit-ja-torjunta/taudit-ja-taudinaiheuttajat-a-o/apinarokko

What were the historical reasons for the resistance to recognizing airborne transmission during the COVID-19 pandemic (Jimenez, Morawska, et al.)? Indoor Air. 21.8.2022. https://onlinelibrary.wiley.com/doi/10.1111/ina.13070

August 21-31

The NHS is being squeezed in a vice. Financial Times. 20.8.2022. https://www.ft.com/content/f36c5daa-9c14-4a92-9136-19b26508b9d2

Pandemic management requires exposure science (MJJantunen). Environment International. 20.8.2022. https://www.sciencedirect.com/science/article/pii/S016041202200397X?via%3Dihub  https://doi.org/10.1016/j.envint.2022.107470

Which COVID boosters to take and when: a guide for the perplexed
A diverse menu of vaccine options leaves people searching for the best route to protection. Nature. 19.8.2022. https://www.nature.com/articles/d41586-022-02221-w

Coronavirus (COVID-19) Infection Survey, UK: 19 August 2022. Percentage of people testing positive for coronavirus (COVID-19) in private residential households in England, Wales, Northern Ireland and Scotland, including regional and age breakdowns. Office for National Statistics (ONS/UK). accessed 19.8.2022. https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/coronaviruscovid19infectionsurveypilot/19august2022

Asiantuntija (Markku Broas) ihmettelee THL:n koronapuheita: ”Suomi ei yksin voi julistaa pandemiaa päättyneeksi”. THL ilmoitti koronaviruksen siirtyneen endeemiseen vaiheeseen. Maailman terveysjärjestön mielestä pandemia jatkuu yhä. Suomen Kuvalehti. 19.8.2022. https://suomenkuvalehti.fi/kotimaa/asiantuntija-ihmettelee-thln-koronapuheita-suomi-ei-yksin-voi-julistaa-pandemiaa-paattyneeksi/

Scientists Discover ”Weak Spot” Across All Major Covid Variants: Study
The weakness can be targeted by neutralising antibodies, potentially paving the way for treatments that would be universally effective across Covid variants, researchers said. NDTV. 19.8.2022. https://www.ndtv.com/world-news/scientists-discover-weak-spot-across-all-major-covid-variants-study-3268899

Health expert warns of spike in monkeypox cases amid shortage of vaccines
Four UK Chief Medical Officers agreed vaccine deployment should be prioritised where there are localised outbreaks. Wales Online 18.8.2022. https://www.walesonline.co.uk/news/health/monkeypox-vaccine-symptoms-cases-contact-24787594

ANYWHERE BUT HERE. China now insists the pandemic didn’t start within its borders. Its scientists are publishing a flurry of papers pointing the finger elsewhere. Science. 18.8.2022. https://www.science.org/content/article/pandemic-start-anywhere-but-here-argue-papers-chinese-scientists-echoing-party-line

COVID-19: respirator masks cut SARS-CoV-2 infections by >40%. JAMA Network Open. 18.8.2022. https://www.univadis.com/viewarticle/covid-19-respirator-masks-cut-sars-cov-2-infections-by-40-ccc791d1-4826-3288-a6ae-ff773bde8950

How much virus does a person with COVID exhale? New research has answers. One ‘superspreader’ with Omicron shed 1,000 times as much viral RNA as those with Alpha or Delta. Nature. 17.8.2022. https://www.nature.com/articles/d41586-022-02202-z

Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients. Lancet Psychiatry. 17.8.2022. https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(22)00260-7/fulltext

Tuore tutkimus antoi huolestuttavia tuloksia koronan uusintatartunnoista – Apulaisylilääkäri: Pandemia ei ole ohi- Yhdysvaltalaistutkimus on vielä vertaisarvioimaton. Sen vahvuutena on kuitenkin suuri aineisto, Husin apulaisylilääkäri sanoo. Mediuutiset. 16.8.2022. https://www.mediuutiset.fi/uutiset/tuore-tutkimus-antoi-huolestuttavia-tuloksia-koronan-uusintatartunnoista-apulaisylilaakari-pandemia-ei-ole-ohi/496876c5-e77b-4996-a12b-19356b8d5af8

Tutkimus osoitti ensimmäistä kertaa, että yhteys matalan sosioekonomisen aseman ja koronasairastavuuden välillä rajoittui ainoastaan maahanmuuttajataustaiseen väestöön. Helsingin Uutiset. 16.8.2022. https://www.helsinginuutiset.fi/paikalliset/4790216

Healthcare Workers Who Wear Better Masks Get Less COVID
— Observational study affirms better odds of dodging infection by wearing a respirator mask. MedpageToday. 15.8.2022. https://www.medpagetoday.com/infectiousdisease/covid19/100227

Green zoning: An effective policy tool to tackle the Covid-19 pandemic., Health Policy. NN.8.2022. https://www.sciencedirect.com/science/article/pii/S0168851021001585

Vanhempia kiellettiin tapaamasta vastasyntynyttä vauvaansa Mikkelissä – koronakanteluita tehty jo yli 3000. Eduskunnan oikeusasiamiehelle ja valtioneuvoston oikeuskanslerille on tehty yhteensä yli 3 000 koronaan tavalla tai toisella liittyvää kantelua. Iltalehti kysyi apulaisoikeusasiamies Pasi Pölöseltä ja oikeuskansleri Tuomas Pöystiltä, mitä kantelut ovat koskeneet ja kuinka virallinen Suomi on selvinnyt pandemiasta. Iltalehti.14.8.2022. https://www.iltalehti.fi/kotimaa/a/dae3e5c1-0571-4bf7-a194-ac5e9dd2840f?utm_source=iltalehti.fi&utm_medium=email&utm_campaign=email_il_uutiskirje

Non-pharmaceutical Interventions and Social Distancing as Intersubjective Care and Collective Protection. Asian Bioethics Review. 13.8.2022. https://link.springer.com/article/10.1007/s41649-022-00212-7

Pandemia ei ole ohi, maskit käyttöön, apulaisylilääkäri kehottaa – uusi koronatartunta voi olla edellistä vaikeampi, uusi tutkimus kertoo
Tuore yhdysvaltalaistutkimus antaa syytä vältellä uutta koronatartuntaa edelleenkin. Iltalehti. 13.8.2022. https://www.iltalehti.fi/terveysuutiset/a/927fa44b-fcc7-4658-b57f-b8f53a0c6366

Seinäjoen keskussairaala on ollut niin täynnä, että naistentautien osastolle on sijoitettu miehiä – koronapotilaita hoidetaan ympäri sairaalaa.
Keskussairaala on ollut täynnä lähes koko kesän. Heikentyneestä koronatilanteesta huolimatta pandemiaosastoa ei aiota avata.YLE Uutiset. 12.8.2022. https://yle.fi/uutiset/3-12573331

Ei vähänkään oireisena kouluun, käsiä pestään armotta – katso tästä vinkit koronaturvalliseen koulunalkuun. Koulut avaavat ovensa ympäri Suomea tämän ja ensi viikon aikana. Maskit ja karanteenit ovat pitkälti eilispäivää, mutta jotkin koronavuosien käytännöt pysyvät. YLE Uutiset. 12.8.2022. https://yle.fi/uutiset/3-12572153

It can feel safer to block out contradictory information that challenges a belief. Cognitive biases and brain biology help explain why facts don’t change minds. The Conversation. 11.8.2022. https://theconversation.com/cognitive-biases-and-brain-biology-help-explain-why-facts-dont-change-minds-186530

August 11-20

Distinguishing features of Long COVID identified through immune profiling. medRxiv. 10.8.2022. https://www.medrxiv.org/content/10.1101/2022.08.09.22278592v1

Hallitus varautuu laittamaan ravintolat ja tapahtumat taas kiinni koronan takia – oikeusoppinut: ”Kestämätön himmeli”. Perustuslakiasiantuntija Pauli Rautiaisen mielestä toistaiseksi voimassa olevien lakien sijaan nyt täytyisi keskittyä rakentamaan pysyvää tartuntatautilakia. Iltalehti. 9.8.2022. https://www.iltalehti.fi/politiikka/a/b39698aa-f62a-4d29-b0ad-fb2e8f852e83

Long COVID: which symptoms can be attributed to SARS-CoV-2 infection? Lancet. 6.8.2022. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)01385-X/fulltext

Post-Covid-19 Symptoms and Conditions Among Children and Adolescents – United States, March 1, 2020-January 31, 2022. CDC MMWR. 5.8.2022. https://www.cdc.gov/mmwr/volumes/71/wr/mm7131a3.htm

Long COVID, Cognitive Impairment, and the Stalled Decline in Disability Rates. FEDS Notes. 5.8.2022. https://www.federalreserve.gov/econres/notes/feds-notes/long-covid-cognitive-impairment-and-the-stalled-decline-in-disability-rates-20220805.htm

Comparative evaluation results of SARS-CoV-2 antigen rapid diagnostic tests passing the sensitivity criteria (in alphabetical order of manufacturers), Germany, 2020–2021 (n = 96). accessed 5.8.2022. https://www.eurosurveillance.org/content/table/10.2807/1560-7917.ES.2021.26.44.2100441.t1?fmt=ahah&fullscreen=true

Itävaltaa järkyttää korona­rokotuksia kannattaneen lääkärin peruuttamaton ratkaisu kuukausien viha­kampanjan jälkeen
Koronatoimien puolesta kampanjoineen Lisa-Maria Kellermayrin kuolema sai tuhannet osoittamaan mieltään Itävallassa. Liittopresidentti Alexander Van der Bellen tuomitsi jyrkästi vihan lietsomisen lääkäriä kohtaan. Ilta=sanomat. 4..8.2022. https://www.is.fi/ulkomaat/art-2000008982689.html

Blood clots, heart problems, kidney failure: COVID creates a higher risk for rare pediatric health problems, new CDC study finds. Fortune. 4.8.2022. https://fortune.com/2022/08/04/covid-creates-higher-risk-kids-children-pediatric-blood-clots-kidney-failure-heart-problems-type-1-diabetes/

Samhällsnytta före individens rättigheter i Sveriges coronastrategi.
Syftet med den svenska coronastrategin har varit att skydda institutioner snarare än individer. Det menar Per Bauhn, professor i praktisk filosofi vid Linnéuniversitetet. Han har utvärderat Sveriges hantering av pandemin i ett bidrag till en internationell samlingsvolym om etik och pandemihantering. Linnéuniversitetet. 3.8.2022. https://lnu.se/mot-linneuniversitetet/aktuellt/nyheter/2022/samhallsnytta-fore-individens-rattigheter-i-sveriges-coronastrategi/

Das sieht der Entwurf für Corona-Maßnahmen ab dem Herbst vor
Der vorgeschlagene Katalog könnte ab Oktober bis April nächsten Jahres gelten. Dieser sieht verpflichtende Basismaßnahmen vor und Möglichkeiten für die Länder. Der Tagesspiegel. 3.8.2022. https://www.tagesspiegel.de/politik/lauterbach-und-buschmann-einig-das-sieht-der-entwurf-fuer-corona-massnahmen-ab-dem-herbst-vor/28570952.html

Tracking Covid-19’s global spread. The disease has spread to every continent and case numbers continue to rise. CNN health. 3.8.2022 Update. https://edition.cnn.com/interactive/2020/health/coronavirus-maps-and-cases/

Heart disease after COVID: what the data say. Some studies suggest that the risk of cardiovascular problems, such as a heart attack or stroke, remains high even many months after a SARS-CoV-2 infection clears up. Researchers are starting to pin down the frequency of these issues and what is causing the damage. Nature. 2.8.2022. https://www.nature.com/articles/d41586-022-02074-3

Why the Chair of the Lancet’s COVID-19 Commission Thinks The US Government Is Preventing a Real Investigation Into the Pandemic. Current Affairs. 2.8.2022. https://www.currentaffairs.org/2022/08/why-the-chair-of-the-lancets-covid-19-commission-thinks-the-us-government-is-preventing-a-real-investigation-into-the-pandemic

Association of Receiving a Fourth Dose of the BNT162b Vaccine With SARS-CoV-2 Infection Among Health Care Workers in Israel. JAMA. 2.8.2022. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2794864

Varautuminen koronatilanteen jatkumiseen kasvatuksessa ja koulutuksessa 1.8.2022.  Opetushallitus. https://www.oph.fi/fi/kehittaminen/varautuminen-koronatilanteen-jatkumiseen-kasvatuksessa-ja-koulutuksessa-182022

Evolution of SARS-CoV-2 Shedding in Exhaled Breath Aerosols. medRxiv. 1.8.2022. https://www.medrxiv.org/content/10.1101/2022.07.27.22278121v2.full

August 1-10

The Efficacy of Facemasks in the Prevention of COVID-19: A Systematic Review. medRxiv. 31.7.2022. https://www.medrxiv.org/content/10.1101/2022.07.28.22278153v1

Initial strategy of vaccinating only known monkeypox contacts was ’doomed to failure’ in the US, experts say. CNN health. 31.7.2022. https://edition.cnn.com/2022/07/30/health/monkeypox-vaccination-strategy/index.html

Spain reports first monkeypox-related death in Europe. CNN. 30.7.2022. https://edition.cnn.com/2022/07/29/europe/spain-first-monkeypox-death-europe-intl-hnk/index.html

Is COVID prematurely aging our immune systems? Repeated SARS-CoV-2 infections may be prematurely aging human immune systems, research suggests. National Post. 30.7.2022. https://nationalpost.com/health/is-covid-prematurely-aging-our-immune-systems

Why The BMJ will no longer report on unsubstantiated press releases. BMJ. 28.7.2022. https://www.bmj.com/content/378/bmj.o1878

Onko korona nyt pysyvästi keskuudessamme? THL:n Salminen: ”Sen kanssa joudutaan elämään ainakin allekirjoittaneen loppuiän”. Koronavirus on tullut keskuuteemme jäädäkseen. THL:n Mika Salminen totesi keskiviikkona pandemian muuttuneen koronaendemiaksi. Mitä endeemisellä taudilla oikein tarkoitetaan? MTV-Uutiset 28.7.2022. https://www.mtvuutiset.fi/artikkeli/onko-korona-on-nyt-pysyvasti-keskuudessamme-thl-n-salminen-sen-kanssa-joudutaan-elamaan-ainakin-allekirjoittaneen-loppuian-verran/8477606#gs.87ezjh

Raju pettymys! Koronan jälkioireet päättävät Maria Huntingtonin kauden
Seitsenottelija oli jo valittu Münchenin EM-kisoihin. Ilta=Sanomat. 28.7.2022. https://www.is.fi/yleisurheilu/art-2000008971328.html

Jari Litmanen kertoo Iltalehdelle, että hänen terveytensä romahti puoleksitoista vuodeksi: ”Elämäni oli pitkään selviytymis­taistelua”. Jari Litmanen sairastui koronavirustautiin heti ensimmäisessä aallossa. Vasta nyt hän tuntee Iltalehden mukaan olevansa voimissaan. Litmanen kertoo nukkuneensa pahimmillaan päivittäin kahdet päiväunet. Helsingin Sanomat. 28.7.2022. https://www.hs.fi/urheilu/art-2000008971090.html?share=ff2d27fd5903f64ef9fdbf58200fea67

THL:n Mika Salminen: Talvella edessä kunnon epidemia. Laitoksen mukaan koronavirus on siirtymässä pandemiasta endemiaan.Verkkouutiset. 27.7.2022. https://www.verkkouutiset.fi/a/thln-mika-salminen-talvella-edessa-kunnon-epidemia/#1debac39

Long COVID and the labour market. Institute for Fiscal Studies.  27.7.2022. https://ifs.org.uk/publications/16121

Wuhanin villieläintori oli koronapandemian alkujuuri, sanovat kaksi uutta tutkimusta. Torilla myytiin muun muassa eläviä punakettuja, mäyriä ja supikoiria. Helsingin Sanomat. 27.7.2022. https://www.hs.fi/tiede/art-2000008968992.html?share=60f33bf3557b3ad84f863b830791776f

Tapio Sade­ojan kolumni: On vain yksi totuus ja se on THL:n totuus. Miksi THL on vähätellyt neljänsien rokotuksien merkitystä, kysyy Tapio Sadeoja. Ilta=Sanomat. 27.7.2022. https://www.is.fi/kotimaa/art-2000008968379.html

Onko apinarokko sittenkään vain seksitauti? Esitimme tämän ja kahdeksan muuta kysymystä virologille. Helsingin yliopiston virologian professori Olli Vapalahti muistuttaa, että apinarokko voi tarttua läheisessä kontaktissa myös pisaratartuntana. Pienille lapsille tauti on erityisen vaarallinen. YLE Uutiset. 26.7.2022.  https://yle.fi/uutiset/3-12551225

Reproduction number of monkeypox in the early stage of the 2022 multi-country outbreak. medRxiv. 26.7.2022. https://www.medrxiv.org/content/10.1101/2022.07.26.22278042v1

Professorin mukaan Suomi on herännyt jälkijunassa pitkittyneen koronataudin riskeihin: ”Britanniassa on noin sata hoitoon erikoistunutta klinikkaa”. Arviot pitkittyneen koronataudin esiintyvyydestä vaihtelevat. Kansallista tutkimusta aiheesta ei vielä ole saatavilla. YLE Uutiset. 26.7.2022. https://yle.fi/uutiset/3-12561417

Isolation facilities for covid-19: towards a person centred approach. The BMJ. 26.7.2022. https://www.bmj.com/content/378/bmj-2021-069558

How long is COVID infectious? What scientists know so far. Those with SARS-CoV-2 are often advised to isolate for only a few days. But evidence is mounting that some people can continue to pass on the virus for much longer. Nature. 26.7.2022. https://www.nature.com/articles/d41586-022-02026-x

The Huanan Seafood Wholesale Market in Wuhan was the early epicenter of the COVID-19 pandemic. Science. 26.7.2022. https://www.science.org/doi/10.1126/science.abp8715

The molecular epidemiology of multiple zoonotic origins of SARS-CoV-2. Science 26.7.2022. https://www.science.org/doi/10.1126/science.abp8337

THL:n Salminen kehottaa päättäjiä harkitsemaan terveydenhuollon resurssien lisäämistä – ”Koronaan ei voida ikuisesti suhtautua toisin kuin muihin tauteihin”. Mika Salminen toivoo, että terveydenhuollon kapasiteettia vahvistettaisiin, jottei yhteiskuntaa tarvitsisi niin herkästi sulkea terveydenhuollon kantokyvyn turvaamisen nimissä. Salminen vertaa koronaa RS-virukseen, joka on toistuva riesa lapsille ja vanhuksille.Mika Salminen toivoo, että terveydenhuollon kapasiteettia vahvistettaisiin, jottei yhteiskuntaa tarvitsisi niin herkästi sulkea terveydenhuollon kantokyvyn turvaamisen nimissä. Salminen vertaa koronaa RS-virukseen, joka on toistuva riesa lapsille ja vanhuksille. Keskipohjanmaa. 25.7.2022. https://www.keskipohjanmaa.fi/uutinen/629659

Preventive Medication for COVID-19 Infection. JAMA. 25.7.2922. https://jamanetwork.com/journals/jama/fullarticle/2794799?guestAccessKey=be88b5a6-16ab-4c8e-9b4a-30a2c91f95d1&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=072522

WHO declares monkeypox a public health emergency of international concern. CNN health. 23.7.2022. https://edition.cnn.com/2022/07/23/health/monkeypox-who-intl/index.html

Korona pitäisi poistaa yleisvaarallisten tartuntatautien joukosta, sanoo THL:n Salminen – näin vastaa STM. MTV Uutiset. 23.7.2022.  https://www.mtvuutiset.fi/artikkeli/korona-pitaisi-poistaa-yleisvaarallisten-tartuntatautien-joukosta-sanoo-thl-n-salminen-nain-vastaa-stm/8473888#gs.6qtyrc

Government must act now to ensure pupils’ learning is not disrupted in ​September. Ministers must use ​the summer break to prepare for Covid surge. Unison. 22.7.2022. https://www.unison.org.uk/news/2022/07/government-must-act-now-to-ensure-pupils-learning-is-not-disrupted-in-%E2%80%8Bseptember/

THL:n Mika Salminen listaa viisi syytä, miksi on hyvä, etteivät poliitikot tai mielipide­vaikuttajat päätä rokotuksista. Salminen kirjoittaa THL:n blogikirjoituksessaan pitävänsä Suomen nykyistä järjestelmää onnistuneena. Heksingin Sanomat. 22.7.2022. https://www.hs.fi/kaupunki/art-2000008962148.html

Rokotusohjelma ei voi perustua mielipiteisiin. THL Blogi. 22.7.2022. https://blogi.thl.fi/rokotusohjelma-ei-voi-perustua-mielipiteisiin/

Euroopassa on käynnissä uusi koronavirusaalto – EU:n tartuntatautiviraston mukaan nousu jatkuu vielä viikkoja.  Euroopan tartuntatautivirasto seuraa tarkasti uutta Intiasta löytynyttä varianttia. Virasto arvioi, että päivitettyjä koronavirusrokotteita saadaan loppusyksystä. YLE Uutiset 22.7.2022. https://yle.fi/uutiset/3-12545135

As new variant spreads, a crucial drug to protect the most vulnerable goes vastly underused. STAT. 22.7.2022.  https://www.statnews.com/2022/07/22/evusheld-covid-drug-for-immunocompromised-underused/

July 21-31

Omicron spike function and neutralizing activity elicited by a comprehensive panel of vaccines. Science. 19.7.2022. https://www.science.org/doi/10.1126/science.abq0203

As Omicron rages on, scientists have no idea what comes next. A rapid succession of subvariants is the new normal—but a completely new variant could still emerge. Science. 19.7.2022. https://www.science.org/content/article/omicron-rages-scientists-have-no-idea-what-comes-next

A seven point plan to suppress covid infections and reduce disruptions. BMJ. 19.7.2022. https://www.bmj.com/content/378/bmj.o1793

Preliminary public health considerations for COVID-19 vaccination strategies in the second half of 2022. ECDC. 18.7.2022. https://www.ecdc.europa.eu/sites/default/files/documents/Preliminary-public-health-considerations-%20COVID-19-vaccination-2022.pdf

Tutkimus: Pfizerin ja Modernan rokotteet antavat pitkäaikaisimman suojan koronaa vastaan. Tuoreen yhdysvaltalaistutkimuksen mukaan mRNA-rokotteet antavat lähes kolme kertaa pidemmän suojan kuin adenovirusvektorirokotteet tai koronatartunta. YLE Uutiset. 18.7.2022. https://yle.fi/uutiset/3-12540734

Editorials: The NHS is not living with covid, it’s dying from it, BMJ. 18.7.2022. https://www.bmj.com/content/378/bmj.o1779

MTV: Sauli Niinistö arvioi, että Suomessa vallitsee koronatietoisuuden puute: ”Se vaatii niitä maskeja ja vähän harkintaa”. Sauli Niinistö vetoaa nyt suomalaisiin ja korostaa, että etenkin riskiryhmäläisten tartuttamista on vältettävä. Kauppalehti. 16.7.2022. https://www.kauppalehti.fi/uutiset/mtv-sauli-niinisto-arvioi-etta-suomessa-vallitsee-koronatietoisuuden-puute-se-vaatii-niita-maskeja-ja-vahan-harkintaa/8c9a52ee-a38d-4198-91e5-9e5684400304

 

Omikron jyllää Kiinassa mittavista sulkutoimista huolimatta.
Koronatartuntojen hillitsemiseksi Kiina käyttää koronasulkuja, pitkiä karanteeniaikoja sekä massatestauksia, vaikka toimet ovat käyneet raskaiksi maan taloudelle. Ilta=Sanomat. 16.7.2022. https://www.is.fi/ulkomaat/art-2000008949177.html

The durability of natural infection and vaccine-induced immunity against future infection by SARS-CoV-2. PNAS. 15.7.2022. https://www.pnas.org/doi/10.1073/pnas.2204336119

Kansanedustaja sai tarpeekseen: THL pitäisi uudistaa kokonaan.
Terhi Koulumies korostaa, että kansanterveysviranomaisen toiminta pitäisi rahoittaa täysin verorahoin. Verkkouutiset.  15.7.2022.  https://www.verkkouutiset.fi/a/kansanedustaja-sai-tarpeekseen-thl-pitaisi-uudistaa-kokonaan/#6d0bdcea

Six-month sequelae of post-vaccination SARS-CoV-2 infection: A retrospective cohort study of 10,024 breakthrough infections. Brain Behaviour Immunity. NN.7.2022. https://www.sciencedirect.com/science/article/pii/S0889159122001118

Koronarokotusten vaikuttavuus Suomessa. Tervetuloa THL:n kuutioraportointiin! THL Update. 14.7.2022. https://sampo.thl.fi/pivot/beta/fi/epirapo/covid19inci/fact_epirapo_covid19inci?row=inciagegroup-639348&column=quadrimestermonth-642723&filter=measure-639168&filter=incivacstatus-669813

Provisional COVID-19 Deaths by HHS Region, Race, and Age. CDC. Update 13.7.2022. https://data.cdc.gov/NCHS/Provisional-COVID-19-Deaths-by-HHS-Region-Race-and/tpcp-uiv5

THL:n selvitys: iäkkäät riskiryhmäläiset hyötyvät selvästi eniten neljännestä koronarokotteesta. THL. 13.7.2022. https://thl.fi/fi/-/thl-n-selvitys-iakkaat-riskiryhmalaiset-hyotyvat-selvasti-eniten-neljannesta-koronarokotteesta

COVID-19 Reinfections May Be Common—But They’re Not Harmless. TIME. 13.7.2022. https://time.com/6196814/covid-19-reinfections-omicron-risks/?

Effectiveness of a fourth dose of mRNA COVID-19 vaccine against all-cause mortality in long-term care facility residents and in the oldest old: A nationwide, retrospective cohort study in Sweden. Lancet. 13.7.2022. https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(22)00162-4/fulltext

Have new COVID variants changed what we know about surface transmission? San Francisco Chronicle 13.7.2022. https://www.sfchronicle.com/bayarea/pandemicproblems/article/covid-surface-transmission-17300795.php

COVID-19’s impact on the brain: Immune response may cause damage. Previous research links COVID-19 infection to brain issues, such as “brain fog” and neurological issues.
In a very small cadaver study, researchers from the National Institutes of Health found that antibodies created by the body in response to COVID-19 infection can cause damage to blood vessels in the brain, causing neurological symptoms.
Scientists believe the discovery of antibody-driven immune complexes on endothelial cells in the brain suggests immune-modulating therapies may help long COVID patients.  Medical News Today. 12.7.2022. https://www.medicalnewstoday.com/articles/covid-19s-impact-on-the-brain-immune-response-may-cause-damage?

Statement on the twelfth meeting of the International Health Regulations (2005) Emergency Committee regarding the coronavirus disease (COVID-19) pandemic. WHO 12.7.2022. https://www.who.int/news/item/12-07-2022-statement-on-the-twelfth-meeting-of-the-international-health-regulations-(2005)-emergency-committee-regarding-the-coronavirus-disease-(covid-19)-pandemic

Kymsote keskeyttää toistaiseksi 12–69-vuotiaiden riskiryhmään kuuluvien 4. koronarokotukset. KymSoten koronainfo. 12.7.2022. https://korona.kymsote.fi/kymsote-keskeyttaa-toistaiseksi-12-69-vuotiaiden-riskiryhmaan-kuuluvien-4-koronarokotukset/

BA.5, Chapter 2. Significant updates from the previous BA.5 story. Eric Topol.  Ground Truths. 11.7.2022. https://erictopol.substack.com/p/ba5-chapter-2

Undercounted Covid-19 cases leave US with a blind spot as BA.5 variant becomes dominant. CNN Health. 11.7.2022. https://edition.cnn.com/2022/07/11/health/ba-5-hidden-covid-case-increase/index.html

EU kehottaa jäsenvaltioita antamaan välittömästi neljännen koronarokotteen yli 60-vuotiaille – Suomi aikoo antaa piikit vasta syyskuussa. THL ei ole vielä ehtinyt perehtyä uuden EU-suosituksen taustoihin. Helsingin Sanomat. 11.7.2022. https://www.hs.fi/kotimaa/art-2000008938641.html?share=97c9021486e54028bbcfd9e2920cf013

July 11-20

Huippututkijat: paremmalla ilmanvaihdolla olisi mahdollista torjua hengitysteitse leviäviä epidemioita. Tutkijoiden tekemien laskelmien perusteella tehostetulla ja oikein suunnatulla sisäilmanvaihdolla riski saada hengitysteitse leviävä tauti, kuten Covid-19, laskisi 20 prosentista 5 prosenttiin. YLE-Uutiset. 10.7.2022. https://yle.fi/uutiset/3-12518229?

Rokotettavien määrä – Kuinka monta ihmistä pitää rokottaa, jotta yksi koronan vuoksi tapahtunut erikoissairaalahoitojakso estyisi? Työpaperi 32/2022. THL https://www.julkari.fi/bitstream/handle/10024/144815/URN_ISBN_978-952-343-896-5.pdf?sequence=1&isAllowed=y

Huolestuttava uusi tutkimus koronasta: Jokainen uusi tartunta voikin olla edellistä kohtalokkaampi. Terveydenhuollossa on syytä varautua lähivuosina hoitamaan koronan aiheuttamia pitkäaikaishaittoja, kuten sydäntauteja ja veritulppia, varoittaa Husin diagnostiikkajohtaja Lasse Lehtonen. Ilta=Sanomat. 9.7.2022. https://www.is.fi/kotimaa/art-2000008931452.html

SARS-CoV-2 Omicron Variant Sub-Lineages BA.4 and BA.5: Evidence and Risk Assessment. [Evidence shows that SARS-CoV-2 reinfection adds risk of all-cause mortality, hospitalization and adverse health outcomes during acute and post-acute SARS-CoV-2 reinfection, and that the risk and burden may increase in a graded manner according to the number of infections. The evidence that SARS-CoV-2 can cause immune dysregulation is increasing. Reducing the risk of SARS-CoV-2 infection and reinfection could reduce overall burden of death and disease in Ontario during the pandemic and longer-term.] Public Health Ontario. 8.7.2022. https://www.publichealthontario.ca/-/media/Documents/nCoV/voc/2022/07/evidence-brief-ba4-ba5-risk-assessment-jul-8.pdf?sc_lang=en

The effect of COVID certificates on vaccine uptake, health outcomes, and the economy. nature 8.7.2022. https://www.nature.com/articles/s41467-022-31394-1?s=09

Long COVID and symptom trajectory in a representative sample of Americans in the first year of the pandemic. Scientific Reports. 8.7.2022. https://www.nature.com/articles/s41598-022-15727-0

Rokotuskeskus rauhoittelee keskustelua koronadisinformaation jakamisesta: Lääkärit katsovat yksittäisiä potilaita, THL koko väestöä. Asiantuntijat ovat eri mieltä koronarokotusten antamisesta. THL on laajentamassa neljännen rokotteen antamista loppukesästä. Infektiolääkärit haluavat, että rokotukset aloitettaisiin heti.YLE Uutiset. 8.7.2022. https://yle.fi/uutiset/3-12529809?

Covid’s chronic effects loom increasingly large. Despite fewer severe cases, the sheer volume of infections means hundreds of thousands are unwell for the long term. Financial Times. 8.7.2022. https://www.ft.com/content/63dcc4d1-8b53-4110-bd44-10e3d1d98585

The Economy Could Have a Long Case of Long Covid. Lingering symptoms for millions of people may place a prolonged drag on economic activity and pose problems for life insurers and healthcare providers. WSJ. 8.7.2022. https://www.wsj.com/articles/the-economy-could-have-a-long-case-of-long-covid-11657272619?st=nax9wf2motn897s&reflink=desktopwebshare_permalink

Australian medical authorities order Zero-COVID activist Dr David Berger to undertake “education” program or be deregistered. World Socialist Web Site. 8.7.2022. https://www.wsws.org/en/articles/2022/07/08/aakm-j08.html?s=03

AHPPC statement on COVID-19 winter update and ongoing health protection measures to support our community. The Australian Health Protection Principal Committee (AHPPC) continues to closely monitor the COVID-19 pandemic situation, drawing upon international and local evidence. Australian Government, Dept of Health and Aged Care. 8.7.2022. https://www.health.gov.au/news/ahppc-statement-on-covid-19-winter-update-and-ongoing-health-protection-measures-to-support-our-community

Opinion The worst virus variant just arrived. The pandemic is not over. Washington Post. 7.7.2022. https://www.washingtonpost.com/opinions/2022/07/07/worst-virus-variant-just-arrived-pandemic-is-not-over/

Pääkirjoitus: Korona ”loppui” kun Kiuru lähti. Heti kun koronaministeri Kiuru lähti sairauslomalle, loppui hallituksessa koronan pelko, mutta kevät ja kesä ovat näyttäneet, ettei korona ole kadonnut mihinkään, kirjoittaa Iltalehden toimittaja Kreeta Karvala. Iltalehti 7.7.2022. https://www.iltalehti.fi/paakirjoitus/a/0e08075e-513a-4709-bc5c-d1ac22444210

Tuomas Aivelo: Koronaviruksen uusinta aaltoa ei tarvitse odotella, se on jo alkanut. Omikronin BA.5-alamuunnos on levinnyt Euroopassa nopeasti, mutta on vaikea ennustaa, kuinka korkeaksi sen aiheuttama tartunta-aalto Suomessa nousee. Iltalehti 7.7.2022. https://www.iltalehti.fi/kotimaa/a/c6631197-9a03-43ca-96e8-e716eda3c3f6

The Truth About COVID Reinfections, Now That There Are New Variants
A viral article paints a picture where we’re constantly sick. Here’s what’s actually going on. (Slate trashes TYEE). Slate. 7.7.2022. https://slate.com/technology/2022/07/covid-reinfection-omicron-wave-forever-plague.html

Effects of Previous Infection and Vaccination on Symptomatic Omicron Infections. New England Journal of Medicine. 7.7.2022. https://www.nejm.org/doi/full/10.1056/NEJMoa2203965

Duration of immune protection of SARS-CoV-2 natural infection against reinfection in Qatar. medRxiv. 7.7.2022. https://www.medrxiv.org/content/10.1101/2022.07.06.22277306v1

How long and effective does a mask protect you from an infected person who emits corona virus-laden particles: by implementing physics-based modeling. medRxiv. 6.7.2022. https://www.medrxiv.org/content/10.1101/2022.07.05.22277221v1

Waning of SARS-CoV-2 vaccine-induced immunity: A systematic review and secondary data analysis. medRxiv. 6.7.2022. https://www.medrxiv.org/content/10.1101/2022.07.04.22277225v1

Long covid -asian­tuntija­ryhmä: Työkyvyttömyysaallon sijaan edessä tuottavuuden lasku
Neurologian professori Risto O. Roine arvioi, että Suomessa pitkittyneen koronataudin tapauksia voi olla jopa kymmenen kertaa virallisia lukuja enemmän. Helsingin Sanomat. 6.7.2022. https://www.hs.fi/visio/art-2000008919913.html

Korona, joka ei katoa. Edes lieväoireisen koronatartunnan jälkeen ei voi huokaista helpotuksesta, koska miljoonille ihmisille taudista on jäänyt lamauttavia oireita kuukausiksi ja vuosiksi, sanoo Akiko Iwasaki, yksi maailman johtavista koronatutkijoista. HS Vision haastattelussa hän kertoo näkemyksensä siitä, mitä tällä hetkellä tiedetään koronaviruksen aiheuttamista pitkäaikaisista oireista. Helsingin Sanomat. 6.7.2022. https://www.hs.fi/visio/art-2000008873226.html

Covid-19 reinfections may increase the likelihood of new health problems. CNN Health. 5.7.2022. https://edition.cnn.com/2022/07/05/health/covid-reinfection-risk/index.html

Now That BA.5 Is Dominant, Stopping It Will Be Difficult. TIME. 5.7.2022. https://time.com/6193890/ba-5-omicron-dominant/

Get Ready for the Forever Plague. Public health officials’ COVID complacency has opened the door to new illnesses and devastating long-term damage (Canada). The TYEE 4.7.2022.  https://thetyee.ca/Analysis/2022/07/04/Get-Ready-Forever-Plague/

Medici famiglia: mai visti tanti casi di covid. Intervenire subito o si rischia la tempesta perfetta. All’Aifa l’appello a modificare il protocollo per la somministrazione degli antivirali, alla politica di investire decisamente sulle quarte dosi. L’intervista di Gerardo D’Amico a Silvestro Scotti. RAI News. 4.7.2022. Medici famiglia: mai visti tanti casi di covid. Intervenire subito o si rischia la tempesta perfetta (rainews.it)

Covid: 84.700 positivi, 63 morti. 118, aumentano i casi di polmonite
Tasso di positività al 26%. Responsabile servizio Emergenza: per le polmoniti responsabile la più recente delle sottovarianti di Omicron, BA.5. ANSA  Cronaca. 3.7.2022. https://www.ansa.it/sito/notizie/cronaca/2022/07/02/covid-84.700-positivi-63-morti.-118-aumentano-i-casi-di-polmonite_14b3783f-bb72-41bd-8dcd-f52cf6ea8c5e.html

Infektio­ylilääkäri kritisoi kovin sanoin THL:n linjauksia: ”Vakavien tautien vähentämiseen on olemassa keino”. Markku Broas toivoo, että rokotteista ja koronan aiheuttamista kuolemista keskusteltaisiin enemmän. Ilta=Sanomat. 2.7.2022. https://www.is.fi/kotimaa/art-2000008921572.html

Kansanedustaja vaatii selvitystä koronakuolleisuudesta – ”Miksi ihmisten ei anneta suojautua tältä hankalalta taudilta?” Pia Kauma epäilee, onko valmistautuminen syksyn korona-aaltoon riittävää. Hän nostaa esiin myös neljännet koronarokotteet. Uusi Suomi. 2.7.2022. https://www.uusisuomi.fi/uutiset/kansanedustaja-vaatii-selvitysta-koronakuolleisuudesta-miksi-ihmisten-ei-anneta-suojautua-talta-hankalalta-taudilta/f5660af1-48e5-4dd6-9382-160dcde2b05e

Aki Lindén tivaa THL:ltä vastausta rokote­kysymykseen: ”Mitä erityis­perusteita Suomessa on?” Ministeri Aki Lindén on vaatinut jo kolme kuukautta, että neljänsiä koronarokotteita annettaisiin nykyistä enemmän. Koronatartuntojen ja sairaalassa olevien määrä on Suomessa jälleen nousussa. Ilta=Sanomat. 2.7.2022. https://www.is.fi/politiikka/art-2000008921639.html

Opinion: Monkeypox—not doing enough is not an option. bmj. 1.7.2022. https://www.bmj.com/content/378/bmj.o1631?

WHO concerned about first cases of monkeypox in children. The organization warns that overall cases in Europe have tripled in the last two weeks, although it has not yet declared the outbreak a global health emergency. El Pais. 1.7.2022. https://english.elpais.com/science-tech/2022-07-01/who-concerned-about-first-cases-of-monkeypox-in-children.html

Immunity and infectivity in covid-19. bmj. 1.7.2022. https://www.bmj.com/content/378/bmj-2020-061402 https://www.bmj.com/content/378/bmj-2020-061402/rapid-responses

Covid-19: Brazil is recording a fifth of all deaths of under 5s. bmj. 1.7.2022. https://www.bmj.com/content/378/bmj.o1634?

Where’s the herd immunity? Our research shows why Covid is still wreaking havoc. ‘Living with the virus’ is proving much harder than the early vaccine success suggested: this fight is far from over. Guardian. 1.7.2022. https://www.theguardian.com/commentisfree/2022/jul/01/herd-immunity-covid-virus-vaccine?

COVID-19 reinfection could be worse than first thought. 9News. 1.7.2022. https://www.9news.com.au/national/covid-19-second-and-third-infections-could-be-worse-than-first-time/66eef293-a9c1-4f1a-bbc2-ca4ab5e5cf02

Association Between BNT162b2 Vaccination and Long COVID After Infections Not Requiring Hospitalization in Health Care Workers. JAMA. 1.7.2022. https://jamanetwork.com/journals/jama/fullarticle/2794072

Novavax is part of the FDA’s COVID-19 booster debate, but its vaccine still hasn’t been authorized. The experimental shot played a front-and-center role during this week’s debate about how best to update the COVID-19 vaccines to better protect against omicron. MarketWatch. 1.7.2022. https://www.marketwatch.com/story/novavax-is-part-of-the-fdas-covid-19-booster-debate-but-its-vaccine-still-hasnt-been-authorized-11656528348

July 1-10

Long distance airborne transmission of SARS-CoV-2: rapid systematic review. bmj. 29.6.2022. https://www.bmj.com/content/377/bmj-2021-068743

Airborne SARS-CoV-2 (Time for an indoor air revolution). Editorial. bmj. 29.6.2022. https://www.bmj.com/content/377/bmj.o1408

Novavax COVID vaccine surprisingly effective against all Omicron variants. New Atlas, 29.6.2022. https://newatlas.com/science/novavax-covid19-vaccine-omicron-booster/

Duration of Shedding of Culturable Virus in SARS-CoV-2 Omicron (BA.1) Infection. NEJM. 29.6.2022. https://www.nejm.org/doi/full/10.1056/NEJMc2202092

First reported case of a person getting COVID from a cat. Scientists in Thailand have established that a tabby passed SARS-CoV-2 to a veterinary surgeon — although such cases of cat-to-human transmission are probably rare. nature. 29.6.2022. https://www.nature.com/articles/d41586-022-01792-y

Bad news for Paxlovid? Coronavirus can find multiple ways to evade COVID-19 drug. Lab studies identify resistance mutations in SARS-CoV-2’s protease, and some circulating variants have them. Science. 29.6.2022. https://www.science.org/content/article/bad-news-paxlovid-coronavirus-can-find-multiple-ways-evade-covid-19-drug?

U.S. FDA advisers recommend change to COVID vaccine composition for fall. Reuters. 29.6.2022. https://www.reuters.com/business/healthcare-pharmaceuticals/us-fda-advisers-meet-discuss-design-future-covid-vaccines-2022-06-28/

BioNTech, Pfizer to start testing universal vaccine for coronaviruses. [Germany’s BioNTech, Pfizer’s partner in COVID-19 vaccines, said the two companies would start tests on humans of next-generation shots that protect against a wide variety of coronaviruses in the second half of the year. Their experimental work on shots that go beyond the current approach include T-cell-enhancing shots, designed to primarily protect against severe disease if the virus becomes more dangerous, and pan-coronavirus shots that protect against the broader family of viruses and its mutations.] Reuters. 29.6.2022. https://www.reuters.com/business/healthcare-pharmaceuticals/biontech-pfizer-starting-testing-universal-coronavirus-vaccine-h2-2022-06-29/

Ensimmäinen tablettimuotoinen koronalääke saapunut Suomeen − tarkoitettu vain vakavan taudin riskiryhmään kuuluville. Tarkat kriteerit on täytettävä ja kotitesti varmistettava laboratoriossa. Mediuutiset. 29.6.2022. https://www.mediuutiset.fi/uutiset/ensimmainen-tablettimuotoinen-koronalaake-saapunut-suomeen-tarkoitettu-vain-vakavan-taudin-riskiryhmaan-kuuluville/eae0f676-6feb-4e09-aa6d-cf5d287b9482

Tapio Sadeojan kolumni: Tuhansia kuollut koronaan Suomessa? Kaikki harhaa vaan on. 4 832 kuollut koronaan. Juhannukseen mennessä tilastoihin ehtineenä, kirjoittaa Tapio Sadeoja. Ilta=Sanomat. 29.6.2022. https://www.is.fi/kotimaa/art-2000008912785.html

Up to one in six people with COVID-19 report long COVID symptoms.
One in six (17%) middle-aged people who report being infected by SARS-CoV-2 also report long COVID symptoms, while this falls to one in 13 (7.8%) among younger adults who reported having Covid-19, according to a new study led by King’s and UCL.Kings College London News Centre. 28.6.2022.  https://www.kcl.ac.uk/news/up-to-one-in-six-people-covid-19-long-covid-symptoms

New Study: COVID-19 May Cause or Accelerate Neurological Diseases. BioSpace. 28.6.2022. https://www.biospace.com/article/research-suggests-covid-19-patients-at-higher-risk-of-parkinson-s-alzheimer-s-stroke-and-bleeding/

Over half of people with Long Covid for two years are declared unfit to work. DutchNews.nl. 28.6.2022. https://www.dutchnews.nl/news/2022/06/over-half-of-people-with-long-covid-for-two-years-are-declared-unfit-to-work/

Australia must plan now for a significant burden of disease and disability due to Long COVID 

Apinarokko uhkaa jäädä kiertämääön ihmisiin (Tuomas Aivelo). TIEDE. 29.6.2022. https://www.tiede.fi/blogit/kaiken-takana-loinen/apinarokko-uhkaa-jaada-kiertamaan-ihmisiin

The BA.5 story. The takeover by this Omicron sub-variant is not pretty. Eric Topol. Ground Truths. 27.6.2022. https://erictopol.substack.com/p/the-ba5-story

China’s first mRNA vaccine is close — will that solve its COVID woes?
Researchers say a highly effective jab will help to avoid hospitals getting overwhelmed, but probably won’t end the country’s ‘zero COVID’ policy. Nature. 22.6.2022. https://www.nature.com/articles/d41586-022-01690-3

Laaja tutkimus: koronarokotteet estivät lähes 20 miljoonaa kuolemaa vuoden aikana. Tutkijoiden mukaan noin 600 000 kuolemaa lisää olisi voitu estää, jos Maailman terveysjärjestön WHO:n tavoite rokottaa 40 prosenttia kaikkien maiden väestöstä viime vuoden loppuun mennessä olisi toteutunut. Helsingin Sanomat. 24.6.2022. https://www.hs.fi/ulkomaat/art-2000008906484.html?share=6ad15524f38aedba1af41699a9a33705

COVID-19 positive patients at higher risk of developing neurodegenerative disorders, new study shows. Medical Press. 24.6.2022. https://medicalxpress.com/news/2022-06-covid-positive-patients-higher-neurodegenerative.html

Global impact of the first year of COVID-19 vaccination: a mathematical modelling study. Lancet Infectious Diseases. 23.6.2022. https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00320-6/fulltext

Global Life Expectancy Falls for First Time Since 1950s Due to Covid. Global life expectancy has fallen for the first time since the 1950s following the Covid-19 pandemic, according to new analysis. The analysis, published by the ONE Campaign, has found that global life expectancy has fallen 1.64 years between 2019 and 2021. Bloomberg. 23.6.2022. https://www.bloomberg.com/news/articles/2022-06-22/global-life-expectancy-falls-for-first-time-since-records-began-due-to-covid-19

STM: Laajamittaiselle koronan testaus- ja jäljitystoiminnalle ei ole enää tarvetta. Strategian tavoitteena on jatkossa ehkäistä riskiryhmäläisten koronatartuntoja, ohjata vaikeaoireiset potilaat hoidon piiriin ja turvata terveydenhuollon kantokyky. Ilta=Sanomat. 23.6.2022. https://web.archive.org/web/20220623054457/https://www.is.fi/kotimaa/art-2000008903640.html

THL muuttaa rokotussuosituksiaan todennäköisesti syksyllä. Osa varastossa olevista rokotteista saattaa olla silloin jo vanhentunut. Suomenmaa. 23.6.2022. https://web.archive.org/web/20220623190609/https://www.suomenmaa.fi/uutiset/thl-muuttaa-rokotussuosituksiaan-todennakoisesti-syksylla/

Long-COVID in children and adolescents: a systematic review and meta-analyses. Scientific Reports, 23.6.2022. https://www.nature.com/articles/s41598-022-13495-5

PAXLOVID-LÄÄKEHOIDON KOHDENTAMINEN COVID-19-INFEKTION HOIDOSSA Paxlovid-lääkitys on tehokas mahdollisimman varhain covid-19-oireiden alun jälkeen aloitettuna ja potilaille, joilla on merkittävä vaikean koronavirustaudin riski. Lääkityksen kohdentaminen on ohjeistettu näillä periaatteilla. Ennen hoitoa diagnoosi on varmistettava terveydenhuollossa tehtävällä PCR-testillä. Hoito tulee aloittaa 5 vrk:n kuluessa oireiden alkamisesta. STM. 22.6.2022. https://www.vsshp.fi/fi/sairaanhoitopiiri/media-tiedotteet-viestinta/tiedotteet/Documents/Ohje%20Paxlovid-hoidon%20kohdentamisesta.pdf

A reinfection red flag. Why a new report is so troubling (Eric Topol). Ground Truths. 22.6.2022.

Gut microbiota from patients with mild COVID-19 cause alterations in mice that resemble post-COVID syndrome. Research Square. 22.6.2022. https://www.researchsquare.com/article/rs-1756189/v1

Long COVID symptoms in SARS-CoV-2-positive children aged 0–14 years and matched controls in Denmark (LongCOVIDKidsDK): a national, cross-sectional study. Lancet. 22.6.2022. https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(22)00154-7/fulltext

Despite Access to Federal COVID-19 Funds to Optimize Ventilation, Most Schools Use Lower-Cost Strategies. JAMA Health Forum. 21.6.2022. doi:10.1001/jamahealthforum.2022.2501

There’s more & more evidence accumulating that COVID-19 causes a chronic illness in many, and that this correlates with virus persistence in tissues. We should really start thinking about this as an illness where virus persists chronically in a significant proportion of people. [Dr. Deepti Gurdasani]. The Reader. 21.6.2022. https://threadreaderapp.com/thread/1539174805198479360.html

June 21-30

Risk of long COVID associated with delta versus omicron variants of SARS-CoV-2. Lancet. 18.6.2022. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00941-2/fulltext

“We Have to Get Out of This Phase”: Ashish Jha on the Future of the Pandemic. President Biden’s COVID czar talks about his public-health philosophy, his Twitter threads, his unlikely path to the White House, and where we go from here. New Yorker. 18.6.2022. https://www.newyorker.com/news/the-new-yorker-interview/we-have-to-get-out-of-this-phase-ashish-jha-on-the-future-of-the-pandemic

Monitoring occurrence of SARS-CoV-2 in school populations: A wastewater-based approach. (Children transmit COVID in communities) PLOS One. 17.6.2022. https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0270168

Covid infections up after Platinum Jubilee celebrations. BBC. 17.6.2022. https://www.bbc.com/news/health-61839777

Outcomes of SARS-CoV-2 Reinfection. Research Square 17.6.2022. https://assets.researchsquare.com/files/rs-1749502/v1/

The covid waves continue to come. Omicron continues to drive waves of covid infections, writes Christina Pagel, but let’s not give up trying to control transmission. bmj. 17.6.2022. https://www.bmj.com/content/377/bmj.o1504?

Outcomes of SARS-CoV-2 Reinfection [US Veterans study, 0…1…2…3 infections]. Research Square. 17.6.2022. https://www.researchsquare.com/article/rs-1749502/v1

COVID-19 in context: Why do people die in emergencies? It’s probably not because of collective psychology. British Journal of Spocial Psychology. https://bpspsychub.onlinelibrary.wiley.com/doi/full/10.1111/bjso.12393

Nature Index Annual Tables 2022: China’s research spending pays off
Experts say the country’s strong scientific performance is likely to be sustained in the coming years. nature. 16.6.2022. https://www.nature.com/articles/d41586-022-01669-0

Ko­ro­na­joh­ta­ja­na tun­ne­tuk­si tullut Mika Sal­mi­nen vaihtaa teh­tä­vää. Kaleva. 16.6.2022. https://www.kaleva.fi/koronajohtajana-tunnetuksi-tullut-mika-salminen-va/4694403?s=03

Koronakriisin hoitoa johtanut Mika Salminen siirtyy uusiin tehtäviin – ”Ei pitäisi kohahduttaa”. Salminen ei usko, että muutos kohahduttaa suomalaisia. ”Minähän olen tässä ollut vain kasvot, jotta THL:n asiantuntijat saavat tehdä rauhassa työtään koronan torjumiseksi.””Nyt puhutaan siitä, että koronaan pitäisi varautua syksyä varten, se on väärä ajattelutapa. Meidän pitää sopeutua siihen, että korona on täällä. Nyt on sopiva aika jättää akuutti vaihe taakse. Koronaa hoidetaan siinä missä muitakin tarttuvia tauteja.”. Helsingin Sanomat. 16.6.2022. https://www.hs.fi/kotimaa/art-2000008889186.html

CLUES TO LONG COVID. Scientists strive to unravel what is driving disabling symptoms. Science. 16.6.2022. https://www.science.org/content/article/what-causes-long-covid-three-leading-theories

Long covid -diagnoosien määrä räjähti Suomessa – Rokotukset eivät pelastaneetkaan pitkittyneeltä koronalta. Helsingin Uutoiset 16.6.2022. https://www.helsinginuutiset.fi/paikalliset/4672874

Persistent circulating SARS-CoV-2 spike is associated with post-acute COVID-19 sequelae. medRxiv.16.6.2022. https://www.medrxiv.org/content/10.1101/2022.06.14.22276401v1

Life expectancy in racial and ethnic groups in the USA. Lancet. 16.6.2022. The Lancet | The best science for better lives

Neurotoxic amyloidogenic peptides in the proteome of SARS-COV2: potential implications for neurological symptoms in COVID-19. nature communications. 15.6.2022. https://www.nature.com/articles/s41467-022-30932-1.epdf

Ylilääkäreiden kannanotto Kainuun hyvinvointialueen organisaatiomuutoksiin: henkilöstöä on kuultu, mutta ei kuunneltu – ”tapa on Kainuun soten kannalta vakavasti haitallinen”. Kainuun Sanomat. 15.6.2022. https://www.kainuunsanomat.fi/artikkeli/ylilaakareiden-kannanotto-kainuun-hyvinvointialueen-organisaatiomuutoksiin-henkilostoa-on-kuultu-mutta-ei-kuunneltu-tapa-on-kainuun-soten-kannalta-vakavasti-haitallinen-220160025/

Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs. Highlights: •mRNA vaccines promote sustained synthesis of the SARS-CoV-2 spike protein. •The spike protein is neurotoxic, and it impairs DNA repair mechanisms. •Suppression of type I interferon responses results in impaired innate immunity. •The mRNA vaccines potentially cause increased risk to infectious diseases and cancer. •Codon optimization results in G-rich mRNA that has unpredictable complex effects. Food and ChemicAL Toxicology. nn.6.2022. Selective visuoconstructional impairment following mild COVID-19 with inflammatory and neuroimaging correlation findings. Molecular Psychiatry. 14.6.2022. https://www.nature.com/articles/s41380-022-01632-5

Selective visuoconstructional impairment following mild COVID-19 with inflammatory and neuroimaging correlation findings. Molecular Psychiatry. 14.6.2022. https://www.nature.com/articles/s41380-022-01632-5

Omicron infection is a poor booster of COVID-19 immunity. People infected with the Omicron variant show poor immune boosting against future SARS-CoV-2 infection. Imperial College, London. 14.6.2022. https://www.imperial.ac.uk/news/237315/omicron-infection-poor-booster-covid-19-immunity/

Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure. Science 14.6.2022. https://www.science.org/doi/10.1126/science.abq1841

Persistent circulating SARS-CoV-2 spike is associated with post-acute COVID-19 sequelae. MedRxiv. 14.6.2022. https://doi.org/10.1101/2022.06.14.22276401

 

People who caught Covid in first wave get ‘no immune boost’ from Omicron. Study of triple vaccinated people also says Omicron infection does little to reduce chance of catching variant again. Guardian. 14.6.2022. https://www.theguardian.com/world/2022/jun/14/people-who-caught-covid-in-first-wave-get-no-immune-boost-from-omicron?CMP=Share_iOSApp_Other

 

Risk of Alzheimer’s Disease Following Influenza Vaccination: A Claims-Based Cohort Study Using Propensity Score Matching. Journal orf Alzheimer’s Disease. 13.6.2022. https://content.iospress.com/articles/journal-of-alzheimers-disease/jad220361#ref020

Japan Has Fewest Covid-19 Deaths Per Capita in OECD, New Data Show
Widespread mask-wearing and relatively little obesity in East Asia are cited for low mortality rate, but lessons remain elusive. WSJ. 13.6.2022. https://www.wsj.com/articles/japan-has-fewest-covid-19-deaths-per-capita-in-oecd-new-data-show-11655116829

Neurotoxic amyloidogenic peptides in the proteome of SARS-COV2: potential implications for neurohttps://www.nature.com/articles/s41467-022-30932-1logical symptoms in COVID-19. nature communications. 13.6.2022.

Relax, This Isn’t the Future of Japanese Tourism. It’s easy to be frustrated with Japan’s slow reopening, but the country needs to learn to let down its guard first.  Bloomberg. 13.6.2022. https://www.bloomberg.com/opinion/articles/2022-06-12/relax-tourism-to-japan-is-not-becoming-like-north-korea#xj4y7vzkg

Covid is making flu and other common viruses act in unfamiliar ways. Washington Post. 13.6.2022. https://www.washingtonpost.com/health/2022/06/13/covid-flu-rsv-viruses/

Yle: Husin johtaja­yli­lääkäri varoittaa kesän korona­kuolemista – ”Kehitys voi olla varsin huolestuttava”. Markku Mäkijärvi pitää kesäkuukausia tartuntojen kannalta riskialttiina, koska ihmiset liikkuvat ja lomailevat paljon. Ilta=Sanomat. 13.6.2022. https://www.is.fi/kotimaa/art-2000008881999.html

Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation. •Respiratory COVID induces CSF cytokine elevation and microglial reactivity •CCL11 activates hippocampal microglia and impairs neurogenesis •Respiratory COVID causes persistent loss of oligodendrocytes and myelinated axons •Respiratory influenza causes similar but less persistent cellular dysregulation. cell. 12.6.2022. DOI:https://doi.org/10.1016/j.cell.2022.06.008

June 11-20

’More work’ to be done’: Key takeaways from the WHO report on origins of the Covid-19 pandemic. CNN World. 10.6.2022. https://edition.cnn.com/2022/06/10/china/who-covid-pandemic-origins-report-intl-hnk/index.html?

Neurodevelopmental Outcomes at 1 Year in Infants of Mothers Who Tested Positive for SARS-CoV-2 During Pregnancy. JAMA. 9.6.2022. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2793178

FDA decision on Novavax’s Covid shots could be delayed to review changes in manufacturing. CNBC. 9.6.2022. https://www.cnbc.com/2022/06/09/fda-decision-on-novavaxs-covid-shots-could-be-delayed-.html

Study Finds Previous Covid-19 Infection Doesn’t Protect Children From Omicron. Forbes. 9.6.2022. https://www.forbes.com/sites/williamhaseltine/2022/06/09/study-finds-previous-covid-19-infection-doesnt-protect-children-from-omicron/?sh=49cf6e9e1176

Concordance of SARS-CoV-2 RNA in Aerosols From a Nurses Station and in Nurses and Patients During a Hospital Ward Outbreak. JAMA. 8.6.2022. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2793153?utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jamanetworkopen&utm_content=mthlyforyou&utm_term=070322

Hallitus laatii pelisääntöjä syksyn korona-aallon varalle – Koronapassilla ei enää voisi kiertää rajoituksia, jos niihin turvaudutaan. Hallitus kerää lausuntoja tartuntatautilakiin ehdotetuista muutoksista. Mediuutiset 8.6.2022. https://www.mediuutiset.fi/uutiset/mu/9f7492b9-942f-4298-b4e8-3ea828ea8161

New York Times: Leviääkö apinarokko ilmassa? Yhdysvaltain tautikeskus suosittelee maskia apinarokkopotilaalle ja hänen perheenjäsenilleen, aerosolitartunnoista puhutaan kuitenkin varoen. Lääkärilehti. 8.6.2022. https://www.laakarilehti.fi/terveydenhuolto/new-york-times-leviaako-apinarokko-ilmassa/?

Osa long covid -potilaista täyttää ME/CFS:n diagnostiset kriteerit – Molempien hoidossa ja kuntoutuksessa korostuu yksilöllisyys ja moniammatillinen yhteistyö. Covid-19-pandemia tulee todennäköisesti lisäämään merkittävästi ME/CFS-potilaiden määrää, kirjoittavat Hanna Markkula, Tuuli Latvala ja Eveliina Leinonen. Mediuutiset. 7.6.2022. https://www.mediuutiset.fi/debatti/osa-long-covid-potilaista-tayttaa-me-cfsn-diagnostiset-kriteerit-molempien-hoidossa-ja-kuntoutuksessa-korostuu-yksilollisyys-ja-moniammatillinen-yhteistyo/c6ca5347-41a1-48bc-aa33-2d721d246e4a

BA.5-variantin osuus yli kolminkertaistunut viikossa Husin alueella
Rokotusten ja aiemmin sairastetun koronan tuomaa suojaa kiertävä variantti yleistyy nopeasti. Lääkärilehti. 7.6.2022. https://www.laakarilehti.fi/terveydenhuolto/ba.5-variantin-osuus-yli-kolminkertaistunut-viikossa-husin-alueella/?

Nirmatrelvir Resistant SARS-CoV-2 Variants with High Fitness in Vitro. bioRxiv. 7.6.2022. https://www.biorxiv.org/content/10.1101/2022.06.06.494921v1

The substitutions L50F, E166A and L167F in SARS-CoV-2 3CLpro are selected by a protease inhibitor in vitro and confer resistance to nirmatrelvir. bioRxiv. 7.6.2022. https://www.biorxiv.org/content/10.1101/2022.06.07.495116v1

U.S. CDC removes mask recommendation from monkeypox travel notice to avoid confusion. Reuters. 7.6.2022. https://www.reuters.com/world/us/us-cdc-removes-mask-recommendation-monkeypox-travel-notice-avoid-confusion-2022-06-07/

Reducing SARS-CoV-2 in Shared Indoor Air. JAMA Wiewpoint. 7.6.2022.  https://jamanetwork.com/journals/jama/fullarticle/2793289

Covid-19: Doctor who sold hydroxychloroquine as “magic bullet” treatment is jailed. bmj. 6.6.2022. https://www.bmj.com/content/377/bmj.o1395?=&utm_source=adestra&utm_medium=email&utm_campaign=usage&utm_content=daily&utm_term=text

Suomessa on varastossa yli 3 miljoonaa koronarokotetta – ylilääkäri kommentoi. Suomen suuret koronarokotevarastot ovat monen tekijän summa. Iltalehti. 6.6.2022. https://www.iltalehti.fi/terveysuutiset/a/1a472435-f0dd-4758-8cbf-a1aef16b9cc0

What Our COVID-19 Response Can Teach Us About Dealing With Monkeypox. TIME. 6.6.2022. https://view.newsletters.time.com/?qs=9cb58f3b3de900675050d37e9b6ffb7f1046c9a1ae9705166182eecc6f650ee06006c91f5ac2b1d08814c8613a974a32c9e21a0b23c631e31989e7d00123d09625d8bc616f83a350777fe2b0696e294c&fbclid=IwAR3-zUmfPNK1KYaybI8s8IhOaAfQRaxLWEvhiiJNJCZOBTphHED9CZ0Hb9k

Short-term Mortality Fluctuations. HMD Short-Term Human Mortality Database. 6.6.2022. https://mpidr.shinyapps.io/stmortality/

How Swedish authorities worked to export “herd immunity” to other countries. The following is a submission to the Global Workers’ Inquest into the COVID-19 Pandemic from anti-COVID activists Keith Begg and Virpi Flyg on the efforts of the Swedish government to export its “herd immunity” strategy of mass infection to countries throughout the world. Begg is a communications specialist from Ireland who holds both Irish and Swedish citizenship, and the founder of Media Watchdogs of Sweden. Flyg is a writer, translator, and social media influencer from Finland. World Socioalist Web Site. 5.6.2022. https://www.wsws.org/en/articles/2022/06/06/swed-j06.html

Suomalaistutkijat alkavat etsiä kiivaasti long covidin alatyyppejä – diagnoosien määrä on jopa nelinkertaistunut lyhyessä ajassa
Helsingin yliopistollisen sairaalan johtaman tutkimushankkeen tavoitteena on selvittää koronavirusinfektion jälkeisten pitkäaikaisten oireiden eli long covidin taustalla olevia mekanismeja.YLE Uutiset. 4.6.2022. https://yle.fi/uutiset/3-12468334

Can long Covid lead to death? A new analysis suggests it could
The CDC is beginning to look at death certificates that indicate more than 100 people who died had long Covid. Politico. 3.6.2022. https://www.politico.com/news/2022/06/03/can-long-covid-lead-to-death-a-new-analysis-suggests-it-could-00036845

Omicron subvariant drives spike in cases and deaths in Portugal
Europe faces prospect of further Covid measures later in the year as share of Omicron BA.5 cases rise in Portugal and Germany. Guardian. 3.6.2022. https://www.theguardian.com/world/2022/jun/03/omicron-covid-subvariant-drives-spike-in-cases-and-deaths-in-portgual?CMP=Share_iOSApp_Other

Lasse Lehtoselta kritiikkiä THL:n rokotussuosituksista: ”Hifistelyä” – näkee myös asiakastyytyväisyyden vaarantuvan. Helsingin ja Uudenmaan sairaanhoitopiirin diagnostiikkajohtaja ja terveysoikeuden professori Lasse Lehtonen antaa kritiikkiä THL:n tänään päivittämästä rokotussuosituksesta. Demokraatti. 2.6.2022. https://demokraatti.fi/lasse-lehtoselta-kritiikkia-thln-rokotussuosituksista-hifistelya-nakee-myos-asiakastyytyvaisyyden-vaarantuvan

Yli 80-vuotiaiden ylikuolleisuudella ei selvää yhteyttä tehosterokotusten myöhäiseen aloitukseen. FaktaBaari. 2.6.2022. https://www.faktabaari.fi/fakta/yli-80-vuotiaiden-ylikuolleisuudella-ei-selvaa-yhteytta-tehosterokotusten-myohaiseen-aloitukseen/

Why did Covid disappear from our collective consciousness so quickly?
Brigid Delaney. Guardian. 2.6.2022. https://www.theguardian.com/commentisfree/2022/jun/03/why-did-covid-disappear-from-our-collective-consciousness-so-quickly

Efficacy and Safety of a Recombinant Plant-Based Adjuvanted Covid-19 Vaccine. NEJM. 2.6.2022. https://www.nejm.org/doi/full/10.1056/NEJMoa2201300

Covid-19: Two million people in the UK are estimated to be experiencing long covid, says ONS. bmj. 1.6.2022. https://www.bmj.com/content/377/bmj.o1391?

Why does viral RNA sometimes persist after recovery from acute infections? PLOS Biology. 1.6.2022.  https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3001687

COVID death tolls: scientists acknowledge errors in WHO estimates
Researchers with the World Health Organization explain mistakes in high-profile mortality estimates for Germany and Sweden.. nature. 1.6.2022. https://www.nature.com/articles/d41586-022-01526-0?utm_source=Nature+Briefing&utm_campaign=1436525283-briefing-dy-20220601&utm_medium=email&utm_term=0_c9dfd39373-1436525283-46822866

Hyvästi, Koronavilkku! Sovellus lopetti toimintansa – Sen kautta tehtiin 64 000 tartuntailmoitusta. Mediuutiset. 1.6.2022. https://www.mediuutiset.fi/uutiset/mu/f72367c1-f0c0-41c1-b36d-82457a0bdf7b?ref=newsletter:e718&utm_source=uutiskirje%40mediuutiset.fi&utm_medium=email&utm_campaign=MU-Uutiskirje-laakari

Great Barrington julkilausuma eli miten fossiilisten polttoaineiden teollisuuden lobbarit kaappasivat keskustelun koronatorjunnasta. GBD Blog. June 2022. https://docs.google.com/document/d/1eLRKtkRg5fnHFs_cgarZWIzsFE6Seya39oCVExD76Kk/mobilebasic

June 1-10

During the Omicron Wave, Death Rates Soared for Older People
Last year, people 65 and older died from Covid at lower rates than in previous waves. But with Omicron and waning immunity, death rates rose again. New York Times. 31.5.2022. https://www.nytimes.com/2022/05/31/health/omicron-deaths-age-65-elderly.html

Mask wearing in community settings reduces SARS-CoV-2 transmission. PNAS. 31.5.2022. https://www.pnas.org/doi/10.1073/pnas.2119266119

Living with covid cannot save lives, but research can. BMJ. 30.5.2022. https://www.bmj.com/content/377/bmj.o1361

Monitoring for SARS-CoV-2 drug resistance mutations in broad viral populations. bioRxiv. 30.5.2022. https://www.biorxiv.org/content/10.1101/2022.05.27.493798v1

COVID-19: Infektionen hinterlassen bei Kindern keinen Antikörperschutz vor Omikron. 30.5.2022. https://www.aerzteblatt.de/nachrichten/134653/COVID-19-Infektionen-hinterlassen-bei-Kindern-keinen-Antikoerperschutz-vor-Omikron?utm_source=dlvr.it&utm_medium=twitter

Secretoglobin family 1D member 2 (SCGB1D2) protein inhibits growth of Borrelia burgdorferi and affects susceptibility to Lyme disease. bioRxiv. 28.5.2022. https://www.biorxiv.org/content/10.1101/2022.05.27.493784v1

COVID-19 in 2022—The Beginning of the End or the End of the Beginning? JAMA. 27.5.2022. https://jamanetwork.com/journals/jama/fullarticle/2793011?

SARS-CoV-2 Omicron BA.2.12.1, BA.4, and BA.5 subvariants evolved to extend antibody evasion. bioRxiv. 26.5.2022. https://doi.org/10.1101/2022.05.26.493517

Virological characteristics of the novel SARS-CoV-2 Omicron variants including BA.2.12.1, BA.4 and BA.5. bioRxiv. 26.5.2022. https://doi.org/10.1101/2022.05.26.493539

On the Trail of Long COVID. TIME. 26.5.2022. https://view.newsletters.time.com/?qs=7655bc242c5b342e5fb155e57cad97209b4badce519bcf744c4012e3ac96471e53f513725b0c4e0158e7cea04ca0ad76012970bcb2e05b541e8b6b0551b0dc6822cf87e979b88be24d3847588b973482&fbclid=IwAR0C8kVgWIbRoWIjs3dNxUWWu4yIvjbAElOvNVeAdAuYjIheN40UFKBGKrE

Evusheld long-acting antibody combination retains neutralising activity against Omicron variants BA.4 and BA.5, according to new study from University of Oxford. AstraZeneca. 25.5.2022. https://www.astrazeneca.com/media-centre/medical-releases/evusheld-long-acting-antibody-combination-retains-neutralising-activity-omicron-variants-ba4-ba5-according-new-study-university-oxford.html

Long COVID after breakthrough SARS-CoV-2 infection. Nature Medicine. 25.5.2022. https://www.nature.com/articles/s41591-022-01840-0

Long COVID risk falls only slightly after vaccination, huge study shows
Results suggest that vaccines offer less protection against lingering symptoms than expected. Nature. 25.5.2022. https://www.nature.com/articles/d41586-022-01453-0

Kuolleisuus on kasvanut, mutta THL ei tingi neljänsien koronarokotteiden ikärajasta – ”En uskonut silmiäni”, sanoo Maijaliisa Aho, 72
Moni ikäihminen odottaa muutoksia rokotusten ikärajoihin. Asiantuntijat ovat erimielisiä, eikä Kansallisen rokotusasiantuntijaryhmän päätöskään ollut yksimielinen.YLE Uutiset. 25.5.2022. https://yle.fi/uutiset/3-12461806

Suomen ensimmäinen apinarokkotartunta hyvin todennäköinen. HUSissa on todettu aikuisella miespotilaalla orthopox-ryhmään kuuluvan viruksen aiheuttama tartunta. Apina- ja isorokkovirukset ovat orthopoxviruksia. Lopullinen varmistus apinarokkotartunnasta saadaan, kun näytteen sekvensointi valmistuu loppuviikolla. STT Info (HUS).  25.5.2022. https://www.sttinfo.fi/tiedote/suomen-ensimmainen-apinarokkotartunta-hyvin-todennakoinen?publisherId=23980819&releaseId=69942501

Researchers Find a Pathway to Prevent COVID Infection. Medscape. 25.5.2022. https://www.medscape.com/viewarticle/974617?

Why the Air at the Gym May Be More Likely to Spread Covid. A new study found exercisers expel a shocking number of tiny aerosol particles when they are working hard. New York Times. 24.5.2022. https://www.nytimes.com/2022/05/24/well/move/covid-gym-air.html

Post-COVID C+onditions Among Adult COVID-19 Survivors Aged 18-64 and >65 Years – United States, March 2020-November 2021. CDC MMWR. 24.5.2022. https://www.cdc.gov/mmwr/volumes/71/wr/mm7121e1.htm

Aerosol particle emission increases exponentially above moderate exercise intensity resulting in superemission during maximal exercise. 23.5.2022. PNAS. https://www.pnas.org/doi/10.1073/pnas.2202521119

As Monkeypox Cases Rise, Nations Are Urged to Examine Vaccine Stores
The United States has stockpiled millions of doses of two smallpox vaccines, also effective against monkeypox. But the outbreaks so far are clustered in other countries. New York Times. 23.5.2022. https://www.nytimes.com/2022/05/23/health/monkeypox-vaccines.html?referringSource=articleShare

COVID-19 symptoms and duration of direct antigen test positivity at a community testing and surveillance site, January 2021-2022. medRxiv. 23.5.2022. https://www.medrxiv.org/content/10.1101/2022.05.19.22274968v1

How Rapid Reinfection Has Changed the Covid Fight. New variants can infect people who had Covid-19 as recently as a few months ago. The Mew Republic. 23.5.2022. https://newrepublic.com/article/166573/reinfection-ba2-omicron-covid

Where is the next SARS-CoV-2 variant of concern?. Lancet. 21.5.2022. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00743-7/fulltext

Widening of inequalities in COVID- 19 years of life lost from 2020 to 2021: a Scottish Burden of Disease Study. JECH. 21.5.2022.https://jech.bmj.com/content/jech/early/2022/05/24/jech-2022-219090.full.pdf

May 21-31

School Masking Policies and Secondary SARS-CoV-2 Transmission. AAP Publications. 20.5.2022. https://publications.aap.org/pediatrics/article/149/6/e2022056687/185379/School-Masking-Policies-and-Secondary-SARS-CoV-2?autologincheck=redirected

Excess Mortality in Massachusetts During the Delta and Omicron Waves of COVID-19. JAMA. 20.5.2022. https://jamanetwork.com/journals/jama/fullarticle/2792738?

Child hepatitis cases up to almost 200, say public health officials. ‘It’s important that parents know the likelihood of their child developing hepatitis is extremely low’ says UKHSA.  Independent. 20.5.2022. https://www.independent.co.uk/news/health/child-hepatitis-public-health-b2083855.html

Monkeypox in Australia: what is it and how can we prevent the spread? The Conversation. 20.5.2022. https://theconversation.com/monkeypox-in-australia-what-is-it-and-how-can-we-prevent-the-spread-183526

So, Have You Heard About Monkeypox? A new viral outbreak is testing whether the world has learned anything from COVID. Atlantic.  20.5.2022. https://www.theatlantic.com/health/archive/2022/05/monkeypox-outbreak-covid-pandemic/629920/

SARSCoV2 variants of concern and variants under investigation in England Technical briefing 42. UK Health Security Agency. 20.5.2022. extension://elhekieabhbkpmcefcoobjddigjcaadp/https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1077180/Technical-Briefing-42-20May2022.pdf

Families Live in Fear as Long-Haul Covid Afflicts More Children
A hospital in Ohio creates a new clinic to treat those patients. Bloomberg. 19.5.2022. https://www.bloomberg.com/news/articles/2021-05-19/long-haul-covid-kids-coronavirus-proving-more-serious-risk-to-children#xj4y7vzkg

Want to prevent pandemics? Stop spillovers. Decision-makers discussing landmark agreements on health and biodiversity must include four actions to reduce the risk of animals and people exchanging viruses. Nature. 19.5.2022. https://media.nature.com/original/magazine-assets/d41586-022-01312-y/d41586-022-01312-y.pdf

Ensimmäinen polio­tapaus 30 vuoteen on vahvistettu Mosambikissa – Virus hävitettiin Afrikasta jo kertaalleen. Maailman terveysjärjestön (WHO) Afrikan-aluejohtaja Matshidiso Moeti totesi uuden löydöksen olevan ”erittäin huolestuttava”. Helsingin Sanomat. 19.5.2022. https://www.hs.fi/ulkomaat/art-2000008830045.html

Korona aiheuttaa edelleen runsaasti poissaoloja työpaikoilta – korvaushakemuksia on niin paljon jonossa, että Kela palkkaa 50 uutta käsittelijää. S-ryhmässä alkuvuosi oli haastava omikronin viedessä työntekijöitä sairauslomille. Pandemian aikana koronapoissaolot ovat pakottaneet jopa sulkemaan yksittäisiä S-ryhmän liikkeitä tai lyhentämään aukioloa. YLE Uutiset. 19.5.2022. https://yle.fi/uutiset/3-12450525

Apinarokko on isorokon varjo. (Aivelo) Tiede. 19.5.2022. https://www.tiede.fi/blogit/kaiken-takana-loinen/apinarokko-isorokon-varjo

Neutralization Escape by the SARS-CoV-2 Omicron Variants BA.2.12.1 and BA.4/BA.5 medRxiv. 19.5.2022. https://www.medrxiv.org/content/10.1101/2022.05.16.22275151v1

Kannattaako koronarokotusta enää ottaa? Tähän ihmisryhmään kuuluvien ei ole vielä syytä mennä kolmannelle piikille, kertoo THL:n Hanna Nohynek. Helsingin Uutiset. 18.5.2022. https://www.helsinginuutiset.fi/paikalliset/4612645

Erkenntnisse zu Covid-Infektionen: Warum manche Menschen kein Corona hatten. Während der Omikron-Welle haben sich Millionen Menschen mit Sars-CoV-2 infiziert. Manche hatten aber bisher noch nie ein positives Testergebnis. Woran kann das liegen? BaZ Wissen. 18.5.2022. https://www.bazonline.ch/warum-manche-menschen-kein-corona-hatten-318416937600?

The pandemic’s true health cost: how much of our lives has COVID stolen? Researchers are trying to calculate how many years have been lost to disability and death. (DALY) Nature. 18.5.2022. https://www.nature.com/articles/d41586-022-01341-7?

Monkeypox – United Kingdom of Great Britain and Northern Ireland. WHO. 18.5.2022. https://www.who.int/emergencies/disease-outbreak-news/item/2022-DON383

U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak. STAT. 18.5.2022. https://www.statnews.com/2022/05/18/spain-portugal-report-monkeypox-cases-raising-specter-of-wider-outbreak/?

Onko kesä peruttu? Tehoavatko rokotteet? Viisi kysymystä ja vastausta Suomeen rantautuneesta uudesta omikronvariantista
Turun yliopistollinen keskussairaala kertoi keskiviikkona löytäneensä potilaalta Suomen ensimmäisen Etelä-Afrikan omikronvariantin. YLE Uutiset. 18.5.2022. https://yle.fi/uutiset/3-12451831

Limited cross-variant immunity from SARS-CoV-2 Omicron without vaccination. nature.18.5.2022. https://www.nature.com/articles/s41586-022-04865-0.

Omicron Infection Induces Low-Level, Narrow-Range SARS-CoV-2 Neutralizing Activity. Lancet. 16.5.2022. https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4099400

Coronavirus may be linked to cases of severe hepatitis in children. Reuters. 16.5.2022. https://www.reuters.com/business/healthcare-pharmaceuticals/coronavirus-may-be-linked-cases-severe-hepatitis-children-2022-05-16/

The Answer to Stopping the Coronavirus May Be Up Your Nose. New York Times. 16.5.2022. https://www.nytimes.com/2022/05/16/opinion/covid-nasal-vaccine.html

Just how accurate are rapid antigen tests? Two testing experts explain the latest data. The Conversation. 16.5.2022. https://theconversation.com/just-how-accurate-are-rapid-antigen-tests-two-testing-experts-explain-the-latest-data-180405?

Avohilmo: Perusterveydenhuollon avohoidon ICD-10 – käyntisyyt. THL jatkuvasti päivittyvä? https://sampo.thl.fi/pivot/prod/fi/avo/perus06/summary_icd1001?alue_0=11810&alue_1=&alue_2=&palvelumuoto_0=33780&ammattiryhm%C3%A4_0=30664&ik%C3%A4luokat_0=109987&sukupuoli_0=11936&mittari_0=100050&drill-diagnoosi=11

How Australia Saved Thousands of Lives While Covid Killed a Million Americans. The United States and Australia share similar demographics, but their pandemic death rates point to very different cultures of trust. New York Times. 15.5.2022. https://www.nytimes.com/2022/05/15/world/australia/covid-deaths.html?referringSource=articleShare

 

Multivariate profile and acute-phase correlates of cognitive deficits in a COVID-19 hospitalised cohort. eClinicalMedicine. NN.5.2022. https://www.sciencedirect.com/science/article/pii/S258953702200147X

Post COVID-19 pulmonary fibrosis; a meta-analysis study. Annals of Medicine and Surgery. NN.5.2022. https://www.sciencedirect.com/science/article/pii/S2049080122003508

SARS-CoV-2 Infection May Present as Acute Hepatitis in Children. Ped Inf Dis J. NN.5.2022. https://journals.lww.com/pidj/fulltext/2021/05000/sars_cov_2_infection_may_present_as_acute.38.aspx

Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens. Lancet Gastroent&Hepatol. 14.5.2022. https://www.sciencedirect.com/science/article/pii/S2468125322001662

Elevated liver enzymes and bilirubin following SARS-CoV-2 infection in children under 10. medRxiv. 14.5.2022. https://www.medrxiv.org/content/10.1101/2022.05.10.22274866v1

Mistä ylikuolleisuusluvut johtuvat? Koronapandemia on sosiaalilääketieteellinen tauti, jonka ilmaantuvuuteen ja haittoihin vaikuttavat niin lääketieteelliset kuin sosiaalisetkin tekijät. Mielipidekirjoitus. Helsingin Sanomat. 14.5.2022. https://www.hs.fi/mielipide/art-2000008812081.html

Tracking covid-19 excess deaths across countries. In many parts of the world, official death tolls undercount the total number of fatalities. Economist. 13.5.2022. https://www.economist.com/graphic-detail/coronavirus-excess-deaths-tracker

You Could Catch Covid Again. And Again. And Even Again. As the virus surges through the US yet again, some people are catching it for a second, third or even fourth time. Bloomberg. 13.5.2022. https://www.bloomberg.com/news/articles/2022-05-13/can-i-get-covid-twice-covid-surges-again-in-us-with-reinfections-rising?

Protecting Children Against Omicron. JAMA. 13.5.2022. https://jamanetwork.com/journals/jama/fullarticle/2792526?guestAccessKey=dce928b5-79bb-4785-978d-20cc768a93cb&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_content=olf&utm_term=051322

Epidemiological update: SARS-CoV-2 Omicron sub-lineages BA.4 and BA.5. ECDC. 13.5.2022. https://www.ecdc.europa.eu/en/news-events/epidemiological-update-sars-cov-2-omicron-sub-lineages-ba4-and-ba5

Premature ageing of the immune system may be one cause of long covid. New Scientist. 12.5.2022. https://www.newscientist.com/article/mg25033343-000-premature-ageing-of-the-immune-system-may-be-one-cause-of-long-covid/

High population burden of Omicron variant (B.1.1.529) is associated with the emergence of severe hepatitis of unknown etiology in children. Int J Infect Dis. 12.5.2022. https://www.ijidonline.com/article/S1201-9712(22)00290-9/fulltext

Sairaanhoitopiiri suosittaa neljänsiä koronarokotteita nyt myös yli 70-vuotiaille kotihoidon tai omaishoidon piirissä oleville – Tampere aloittaa heti
Jo aiemmin neljänsiä rokotuksia on suositeltu yli 80-vuotiaille. YLE Uutiset. 12.5.2022. https://yle.fi/uutiset/3-12441549

”Koronakuolleisuuden voimakas kasvu jäänyt pimentoon”, sanoo HUSin Lasse Lehtonen – Suomi saattaa tätä menoa kiilata Ruotsin ohi
Lehtosen mukaan väärä tilannekuva voi vähentää ihmisten hakeutumista tehosterokotuksiin. YLE Uutiset. 12.5.2022. https://yle.fi/uutiset/3-12440967

Akuutteja maksatulehduksia havaittu useissa Euroopan maissa, ei yhteyttä koronavirukseen – Suomessa ei viitteitä tapausten lisääntymisestä. Keski-Uusimaa. 12.5.2022. https://www.keski-uusimaa.fi/paikalliset/4600549

Japanese researcher suggests ties between omicron variant and severe hepatitis in children, Japan Times. 12.5.2022. https://www.japantimes.co.jp/news/2022/05/12/national/science-health/japanese-researcher-omicron-hepatitis-children/

Health outcomes in people 2 years after surviving hospitalisation with COVID-19: a longitudinal cohort study. Lancet. Respiratory Medicine. 11.5.2022. https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(22)00126-6/fulltext

 

May 11-20

THL:n kaksoisrooli rokotteiden tutkimuksessa ja hankinnassa sai oikeuskanslerin vaatimaan riippumattomuuden vahvistamista. SSS.fi. 10.5.2022. https://www.sss.fi/2019/05/oikeuskansleri-vaatii-rokotetutkimuksen-ja-hankintojen-selkeampaa-erottamista-thln-toiminnassa/

Fulminant onset COVID-19: predictors and outcome. BMJ Postgraduate Medical Journal. 10.5.2022. https://pmj.bmj.com/content/early/2022/05/10/postgradmedj-2022-141724

Suun kautta otettavia koronalääkkeitä ei toiveista huolimatta ole saatu Suomeen – neuvottelut junnaavat tai lisänäyttöä vaaditaan
Tuore tutkimustulos kertoo, että koronalääkkeistä remdesiviiri vähentää varmasti kuolleisuutta varhain aloitettuna. Suomalaisprofessori toivoo, että lääkkeitä käyttöönotettaessa niiltä vaadittaisiin laajempaa tutkimusnäyttöä. YLE-Uutiset. 10.5.2022. https://yle.fi/uutiset/3-12430354?utm_source=social-media-share&utm_medium=social&utm_campaign=ylefiapp

Are COVID surges becoming more predictable? New Omicron variants offer a hint. Omicron relatives called BA.4 and BA.5 are behind a fresh wave of COVID-19 in South Africa, and could be signs of a more predictable future for SARS-CoV-2. Nature. 10.5.2022. https://www.nature.com/articles/d41586-022-01240-x?

Effectiveness of influenza vaccination against SARS-CoV-2 infection among healthcare workers in Qatar. medRxiv. 10.5.2022. https://www.medrxiv.org/content/10.1101/2022.05.09.22274802v1.full

New versions of Omicron are masters of immune evasion. Vaccines and prior infection still prevent severe disease from new SARS-CoV-2 strains. Science. 10.5.2022. https://www.science.org/content/article/new-versions-omicron-are-masters-immune-evasion

Covid-19: Fourth dose of mRNA vaccines is safe and boosts immunity, study finds. BMJ. 10.5.2022. https://www.bmj.com/content/377/bmj.o1170?

Feature: How Hong Kong’s vaccination missteps led to the world’s highest covid-19 death rate. Omicron has taken Hong Kong from having one of the lowest covid-19 death rates in the world to having the highest daily death rate per capita. A key reason for this is the island’s handling of vaccination. BMJ. 9.5.2022. https://www.bmj.com/content/377/bmj.o1127?

The route back to 2% inflation − speech by Michael Saunders (impact of COVID & Long COVID on workforce) 9.5.2022. https://www.bankofengland.co.uk/speech/2022/may/michael-saunders-speech-at-the-resolution-foundation-event

Surviving the pandemic is only half the battle: ‘Long COVID’ could affect a billion in just a few years. Fortune. 8.5.2022. https://fortune.com/2022/05/08/surviving-pandemic-half-the-battle-long-covid-growing-public-health-crisis-could-affect-a-billion-in-just-a-few-years/

Suomi kärkisijoilla koronakuolleisuustilastossa – Lasse Lehtonen: ”Epäonnistumiseen on vaikuttanut viisi tekijää”. Kauppalehti. 8.5.2022. https://www.kauppalehti.fi/uutiset/suomi-karkisijoilla-koronakuolleisuustilastossa-lasse-lehtonen-epaonnistumiseen-on-vaikuttanut-viisi-tekijaa/d9ec49a7-8766-46b5-a2a0-f7e737ea4a9c?ref=whatsapp:6978

Estimates of excess mortality for the five Nordic countries during the Covid-19 pandemic 2020-2021. medRxiv. 7.5.2022. https://www.medrxiv.org/content/10.1101/2022.05.07.22274789v1.full.pdf

Prevalence of ongoing symptoms following coronavirus (COVID-19) infection in the UK: 6 May 2022
Estimates of the prevalence of self-reported long COVID and associated activity limitation, using UK Coronavirus (COVID-19) Infection Survey data. Office of National Statistics. 6.5.2022. https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/prevalenceofongoingsymptomsfollowingcoronaviruscovid19infectionintheuk/6may2022

Omicron as severe as other COVID variants -large U.S. study. Reuters. 6.5.2022. https://www.reuters.com/business/healthcare-pharmaceuticals/omicron-severe-previous-covid-variants-large-study-finds-2022-05-05/

Näin 4. koronarokotuksen suositus laajenee – Mika Salminen: Suomeen tulossa rauhallinen kesä. Laajennuksella pyritään estämään heikossa kunnossa olevien tartuntoja. Asiantuntijat odottavat kesästä rauhallista, mutta epidemia nostanee päätään taas syksyllä. Uusi Suomi. 5.5.2022. https://www.uusisuomi.fi/uutiset/nain-4-koronarokotuksen-suositus-laajenee-mika-salminen-suomeen-tulossa-rauhallinen-kesa/565bef5e-613d-4f62-b23f-b0cb7b4aa53c

SARS-CoV-2 and its variants, but not Omicron, induces severe thymic atrophy and impaired T cell development. Research Square. 5.5.2022. https://www.researchsquare.com/article/rs-1581769/v1

Long COVID or Post-COVID Conditions. CDC. 5.5.2022. https://www.cdc.gov/coronavirus/2019-ncov/long-term-effects/index.html

Tehohoidon tilannekuva: COVID-19 teho-osastoilla.   Kansallinen tehohoidon koordinoiva toimisto Kuopion yliopistollinen sairaala. Raportti 4.5.2022. https://www.psshp.fi/documents/194344/209627/Tehohoidon+tilannekuva+-+Koordinoivan+toimiston+raportti+2022_05_04.pdf/32c19e78-75ca-02dd-14bc-c50965ae4a04

Mitä maskien hyödyistä oikeasti tiedetään? Maskisuositus päättyi, mutta maski kannattaisikin vaihtaa hengityksensuojaimeen, jos haluaa välttää koronan. Lääkärilehti. 4.5.2022. https://www.laakarilehti.fi/terveydenhuolto/mita-maskien-hyodyista-oikeasti-tiedetaan/?public=e5870728c558cf14d30dff51e32e1935

The Children Left Behind by Long Covid. As the world pretends the pandemic is over, at least a half-million children in the U.S. are struggling with the mysterious disease. Bloomberg. 4.5.2022. https://www.bloomberg.com/news/features/2022-05-04/long-covid-in-kids-has-effects-that-last-beyond-hospital

Lasting brain impacts of severe COVID-19 equivalent to 20 years of ageing. Imperial College. 3.5.2022. https://www.imperial.ac.uk/news/236034/lasting-brain-impacts-severe-covid-19-equivalent/

Long COVID: As much as 75% of hospital patients still not ’fully recovered’. -Researchers followed around 2,000 people who were hospitalized due to a COVID-19-related illness. Of the participants, only 1 in 4 reported feeling fully recovered a year after they were released from the hospital.
Some factors the researchers believe contributed to a poorer outcome include obesity and requiring the use of a ventilator during their hospital stay. MedicalNewsToday. 3.5.2022. https://www.medicalnewstoday.com/articles/long-covid-as-much-as-75-of-hospital-patients-still-not-fully-recovered

SARS-CoV-2 Omicron Variant is as Deadly as Previous Waves After Adjusting for Vaccinations, Demographics, and Comorbidities. Research QSARS-CoV-2 Omicron Variant is as Deadly as Previous Waves After Adjusting for Vaccinations, Demographics, and Comorbidities. Research Square. 2.5.2022. https://www.researchsquare.com/article/rs-1601788/v1

Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses [Marjukka Myllärniemi]. Lancet. 2.5.2022. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00519-0/fulltext

Postacute COVID-19 is Characterized by Gut Viral Antigen Persistence in Inflammatory Bowel Diseases. Gastroenterology. 1.5.2022. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057012/

Inflammasome activation in infected macrophages drives COVID-19 pathology. bioRxiv. 1.5.2022. https://www.biorxiv.org/content/10.1101/2021.09.27.461948v2

May 1-10

 

 

Fulminant onset COVID- 19: predictors and outcome. BMJ. 30.4.2022. extension://elhekieabhbkpmcefcoobjddigjcaadp/https://pmj.bmj.com/content/postgradmedj/early/2022/05/10/postgradmedj-2022-141724.full.pdf

The 4 physician groups leading the political antivax movement. A physician-led attack on public health is being mediated by the Big 4: The Great Barrington Declaration, America’s Front Line Doctors, Frontline Critical Care Alliance, and the Unity Project. MisinformationKills’s Newsletter. 30.4.2022. https://misinformationkills.substack.com/p/the-4-physician-groups-leading-the?s=r

Protection against Omicron re-infection conferred by prior heterologous SARS-CoV-2 infection, with and without mRNA vaccination. medRxiv. 29.4.2022.https://globalnews.ca/news/8688590/long-covid-symptoms-children/ https://www.medrxiv.org/content/10.1101/2022.04.29.22274455v1.full

Multivariate profile and acute-phase correlates of cognitive deficits in a COVID-19 hospitalised cohort. eClinicalMedicine. 28.4.2022. https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(22)00147-X/fulltext

Long-term mortality following SARS-CoV-2 infection: A national cohort study from Estonia. Lancet Regional Health Europe, 28.4.2022. https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(22)00087-4/fulltext

South Africa is being hit hard by COVID again. Here is what that means for the US. It’s too soon to know whether the BA.4 and BA.5 omicron variants will take off in the U.S. as they are in South Africa. But some experts are anxious. USA Today. 28.4.2022. https://eu.usatoday.com/story/news/health/2022/04/28/south-africa-omicron-ba-4-ba-5-what-means-us/9553483002/

Monitoring SARS-CoV-2 in air and on surfaces and estimating infection risk in buildings and buses on a university campus. Journal of Exposure Science & Environmental Epidemiology. 27.4.2022. https://www.nature.com/articles/s41370-022-00442-9

Critical weaknesses in shielding strategies for COVID-19. PLOS Global Public Health. 26.4.2022. https://journals.plos.org/globalpublichealth/article?id=10.1371/journal.pgph.0000298

Moderna’s new COVID-19 booster protects better against Omicron and other variants. MedicalNewsToday. 25.4.2022. https://www.medicalnewstoday.com/articles/modernas-new-covid-19-booster-protects-better-against-omicron-other-variants?

COVID-19 and the Brain: The Neuropathological Italian Experience on 33 Adult Autopsies. MDPI (Biomolecules) 25.4.2022. https://www.mdpi.com/2218-273X/12/5/629

Investigation into acute hepatitis of unknown aetiology in children in England. Technical briefing. UK Health Security Agency, 25.4.2022. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1071198/acute-hepatitis-technical-briefing-1_4_.pdf

A rampage through the body. The lungs are ground zero, but COVID-19 also tears through organ systems from brain to blood vessels. Science. 24.4.2022. https://www.science.org/doi/10.1126/science.368.6489.356

WHO recommends highly successful COVID-19 therapy (Paxlovid) and calls for wide geographical distribution and transparency from originator. WHO.  22.4.2022. https://www.who.int/news/item/22-04-2022-who-recommends-highly-successful-covid-19-therapy-and-calls-for-wide-geographical-distribution-and-transparency-from-originator

An mRNA vaccine with a twist—it copies itself—protects against COVID-19. Company’s limited data release backs promise of new, lower dose vaccine designed to be easier to distribute and cheaper. Science. 21.4.2022. https://www.science.org/content/article/mrna-vaccine-twist-it-copies-itself-protects-against-covid-19?

Everything You Need to Know About the Hepatitis Outbreak Among Children. Is the number of cases in Israel unusually high, what are the symptoms of the disease and is it linked to the coronavirus? Haaretz explains. Haaretz. 21.4.2022. https://www.haaretz.com/israel-news/everything-you-need-to-know-about-the-hepatitis-outbreak-among-children-1.10754895

Israel Examining 12 Cases of Kids’ Hepatitis After WHO Warning
After 84 cases of hepatitis in children were discovered in the U.K. without a known cause, Israel begins monitoring similar cases in hopes of finding an explanation for the recent surge. Haaretz. 21.4.2022. https://www.haaretz.com/israel-news/israel-examining-12-cases-of-kids-hepatitis-after-who-warning-1.10752779

Policy stringency and mental health during the COVID-19 pandemic: a longitudinal analysis of data from 15 countries. Lancet Public Health. 21.4.2022.  https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(22)00060-3/fulltext

Kaksi kokenutta lääkäriä vaatii neljänsiä rokotteita entistä nuoremmille – viidessä kuukaudessa koronakuolemia on ollut Suomessa yli 2300. HUSin Eeva Ruotsalainen ja Länsi-Pohjan Markku Broas vaativat neljänsien rokotteiden ikärajan laskemista pikaisella aikataululla. Näin on tehty myös useissa muissa maissa. YLE Uutiset. 21.4.2022. https://yle.fi/uutiset/3-12412961

April 21-30

In-person schooling and associated COVID-19 risk in the United States over spring semester 2021. Science Advances. 20.4.2022. https://www.science.org/doi/10.1126/sciadv.abm9128

Ruotsin valtion­epidemiologi Anders Tegnell ei saanutkaan töitä WHO:sta. Rokotteiden saannin turvaamiseen liittyvän työpaikan oli tarkoitus sijaita WHO:n päämajassa Sveitsin Genevessä. Helsinngin Sanomat. 20.4.2022. https://www.hs.fi/ulkomaat/art-2000008763814.html

Maskeista luovutaan Helsingin seudun joukko­liikenteessä – Finnair tarkastelee maski­vaatimustaan lähi­aikoina. Helsingin seudun liikenne luopuu yleisestä maskisuosituksesta. Helsingin Sanomat. 20.4.2022. https://www.hs.fi/kaupunki/art-2000008763129.html

UK to have slowest growth of G7 nations in 2023, says IMF. PM’s claims that Britain has strongest rebound in group undermined by fund’s latest economic forecast (COVID pandemic).  Financial Times. 19.4.2022. https://www.ft.com/content/4ac7e454-5a0c-4094-90af-fb54404d45a0

THL:n Mika Salminen tokaisi Ylellä työterveydestä ”suosittu mutta typerä”– ja palautetta vyöryy. Mika Salmisen mielestä terveydenhuoltojärjestelmän pitäisi olla kaikille sama riippumatta siitä, käykö ihminen töissä. Mediuutiset. 19.4.2022. https://www.mediuutiset.fi/uutiset/mu/dd510566-85d2-4472-9165-4e1e81db3909

Global COVID-19 Death Toll May Be Triple the Reported Deaths. JAMA. 19.4.2022. https://jamanetwork.com/journals/jama/fullarticle/2791213?

Pulmonary fibrosis seen in half of COVID-19 survivors. Univadis. 18.4.2022. https://www.univadis.com/viewarticle/pulmonary-fibrosis-seen-in-half-of-covid-19-survivors-76f7a96b-ee38-31c8-9986-f9aa25b835a3?

Six-month sequelae of post-vaccination SARS-CoV-2 infection: A retrospective cohort study of 10,024 breakthrough infections. Brain Behaviour and Immunity. 18.4.2022. https://reader.elsevier.com/reader/sd/pii/S0889159122001118?

Dose-response modelling of endemic coronavirus and SARS-CoV-2: human challenge trials reveal the individual variation in susceptibility. medRxiv. 16.4.2022. https://doi.org/10.1101/2022.04.07.22273549; t

Global Prevalence of Post COVID-19 Condition or Long COVID: A Meta-Analysis and Systematic Review. J Infect Dis. 16.4.2022. https://pubmed.ncbi.nlm.nih.gov/35429399/

Vaccines are no match for long Covid. Treating it is science’s next great challenge. Guardian. 16.4.2022. https://www.theguardian.com/commentisfree/2022/apr/16/vaccines-long-covid-science?CMP=Share_AndroidApp_Other

Protocol for isolation and analysis of small volatile microbiome metabolites from human or mouse samples.STAR Protocols 15.4.2022. https://star-protocols.cell.com/protocols/1569?twclid=2-6ci34ce4rrh3velfxq0m1y76w

Even mild COVID-19 can cause your brain to shrink. Recent brain imaging shows the disease can cause physical changes equivalent to a decade of aging and trigger problems with attention and memory. Exactly why is still a mystery. National Geographic. 15.4.2022. https://www.nationalgeographic.com/magazine/article/even-mild-covid-19-can-cause-your-brain-to-shrink?

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland. WHO. 15.4.2022. https://www.who.int/emergencies/disease-outbreak-news/item/acute-hepatitis-of-unknown-aetiology—the-united-kingdom-of-great-britain-and-northern-ireland

FDA authorizes first Covid-19 breath test. CNN health. 15.4.2022. https://edition.cnn.com/2022/04/14/health/covid-breath-test/index.html?

Estimating excess mortality due to the COVID-19 pandemic: a systematic analysis of COVID-19-related mortality, 2020–21. Lancet. 14.4.2022. https://www.thelancet.com/action/showPdf?pii=S0140-6736%2821%2902796-3

Hundreds are still dying from Covid every day. Why is Paxlovid sitting on shelves? The supply of Pfizer’s highly effective antiviral pill has rapidly increased, but many physicians still aren’t prescribing it. NBCNews.14.4.2022. https://www.nbcnews.com/health/health-news/covid-antiviral-pill-paxlovid-underused-supply-rcna24200

COVID-19 Autopsies Reveal Underreporting of SARS-CoV-2 Infection and Scarcity of Co-infections.  Frontiers in Medicine. 14.4.2022. https://www.frontiersin.org/articles/10.3389/fmed.2022.868954/full

SARS-CoV-2 Actively Infects And Kills Lymphoid Cells. Forbes. 14.4.2022. https://www.forbes.com/sites/williamhaseltine/2022/04/14/sars-cov-2-actively-infects-and-kills-lymphoid-cells/?sh=2c22257786b8

Po­ti­laan Lää­kä­ri­leh­ti: Neu­ro­lo­gian pro­fes­so­rin mukaan ko­ro­na­tar­tun­nan vält­te­ly on yhä jär­ke­vää, Koro­na­tar­tunnan vält­tely on neuro­logian pro­fes­sorin Ris­to O. Roi­neen mukaan edelleen jär­kevää. Roine kommentoi asiaa Potilaan lääkärilehdessä. Kaleva. 14.4.2022. https://www.kaleva.fi/potilaan-laakarilehti-neurologian-professorin-muka/4521049

SARS-CoV-2 Actively Infects And Kills Lymphoid Cells. Forbes. 14.4.2022. https://www.forbes.com/sites/williamhaseltine/2022/04/14/sars-cov-2-actively-infects-and-kills-lymphoid-cells/?sh=cf4122486b89

Unmasked Facies. JAMA. 14.2.2022. https://jamanetwork.com/journals/jama/fullarticle/2791316

Omikron BA.2 on nyt yleisin jätevesien koronavirusmuunnos Koronaviruksen RNA:n kokonaismäärä Suomen jätevesissä on edelleen korkealla tasolla. Mediuutiset. 13.4.2022. https://www.mediuutiset.fi/uutiset/mu/00b5d440-733e-49df-aa28-c181927582c6

Statement on the eleventh meeting of the International Health Regulations (2005) Emergency Committee regarding the coronavirus disease (COVID-19) pandemic. WHO. 13.4.2022. https://www.who.int/news/item/13-04-2022-statement-on-the-eleventh-meeting-of-the-international-health-regulations-(2005)-emergency-committee-regarding-the-coronavirus-disease-(covid-19)-pandemic

COVID-19: “THE ELIMINATION OF THE VIRUS IS ALWAYS POSSIBLE”
Interview with Yaneer Bar-Yam. World Health Network. 12.4.2022. https://www.worldhealthnetwork.global/yaneer-interview

 

Gastrointestinal symptoms and fecal shedding of SARS-CoV-2 RNA suggest prolonged gastrointestinal infection. Clinical Advances. 12.4.2022. https://www.cell.com/med/fulltext/S2666-6340(22)00167-2

COVID-19: Current cases. Information about confirmed and probable cases of COVID-19 in New Zealand. Ministry of Health. 11.4.2022. https://www.mediuutiset.fi/uutiset/mu/d12f17a8-a11a-4aad-a02a-8c47c99a4834

NHS chiefs call for return of masks and limits on indoor mixing. The NHS Confederation wants a return to mask use. Health chiefs want the government to reconsider its ’living with Covid plan’ and are urging a return to mask use, accusing No10 of abandoning ”any interest in Covid whatsoever.” LBC. 11.4.2022. https://www.lbc.co.uk/news/nhs-chiefs-call-for-return-of-masks-and-limits-on-indoor-mixing/

Postmortem Assessment of Olfactory Tissue Degeneration and Microvasculopathy in Patients With COVID-19. JAMA Neurology. 11.4.2022. https://jamanetwork.com/journals/jamaneurology/fullarticle/2790735

Aivot ottavat koronasta osumaa. Korona ei vanhenna aivoja kymmentä vuotta, vaan kohutussa brittitutkimuksessa havaittiin sen aiheuttavan volyymikatoa aivojen etualaosassa etenkin iäkkäillä. Lääkärilehti. 11.4.2022. https://www.laakarilehti.fi/terveydenhuolto/aivot-ottavat-koronasta-osumaa/

Japan’s Low-Key Covid Campaign Has Lessons for China
The strident efforts in the People’s Republic are in stark contrast to the restrained but more sustainable efforts by its old rival to the east. Bloomberg. 11.4.2022. https://www.bloomberg.com/opinion/articles/2022-04-10/japan-s-low-key-covid-campaign-is-more-sustainable-than-china-s-all-out-efforts

April 11-20

Tutkimukset osoittavat, että vähintään 30 prosenttia Suomen väestöstä on saanut koronatartunnan – THL:n Salminen: Osuus voi olla vielä tätäkin isompi. Tutkimukset perustuvat satunnaisotantaan, jossa on tarkasteltu verinäytteistä löydettyjä vasta-aineita. Löydetyt määrät ovat paljon virallisia tartuntalukuja suuremmat, ja tämäkin arvio on vain minimimäärä. YLE Uutiset. 10.4.2022. https://yle.fi/uutiset/3-12424610

Erikoislääkäri Maria Juusela pohtii, pitäisikö meillä olla itsenäinen koronapandemian seurantalaskuri? Juusela myös ihmettelee, missä viipyvät päätökset ikäihmisten 4. rokotteista ja kolmas rokotekierros 12–17-vuotiaille? MediUutiset. 10.4.2022. https://www.mediuutiset.fi/uutiset/mu/d12f17a8-a11a-4aad-a02a-8c47c99a4834

Notes from the Field: SARS-CoV-2 Omicron Variant Infection in 10 Persons Within 90 Days of Previous SARS-CoV-2 Delta Variant Infection — Four States, October 2021–January 2022. CDC Morbidity and Mortality Weekly Report. 8.4.2022. https://www.cdc.gov/mmwr/volumes/71/wr/mm7114a2.htm

”Tästä tulee tauti muiden joukossa” – Koronaepidemiassa ei ole näkynyt laantumisen merkkejä, mutta asiantuntijat toivovat, että kevään epidemia­huippu olisi jo saavutettu. ”Todennäköisesti neljänsiin rokotuksiin tullaan menemään myöskin nuoremmissa ikäryhmissä, mutta ajoitus ja ajankohta täytyy määrittää tarkan seurantatiedon perusteella”, sanoi Taneli Puumalainen sosiaali- ja terveysministeriöstä. Helsingin Sanomat. 7.4.2022. https://www.hs.fi/kotimaa/art-2000008733903.html

Korona piinaa jatkossakin: ”Suurin osa tulee sairastamaan monta kertaa elämänsä aikana” (Mika Salminen). MTV Uutiset. 7.4.2022. https://www.mtvuutiset.fi/artikkeli/korona-piinaa-jatkossakin-suurin-osa-tulee-sairastamaan-monta-kertaa-elamansa-aikana/8397892#gs.9jqtea

The Latest on Long Covid Research with Dr. Iwasaki. YouTube. 7.4.2022. https://www.youtube.com/embed/CF4j-EVPlPU

Use of face masks did not impact COVID-19 incidence among 10–12-year-olds in Finland. medRxiv. 7.4.2022. https://www.medrxiv.org/content/10.1101/2022.04.04.22272833v1

Covid-19: Symptomatic infection with omicron variant is milder and shorter than with delta, study reports. BMJ. 7.4.2022. https://www.bmj.com/content/377/bmj.o922

COVID-19 Linked to Increased Risk of Blood Clots Even Months Later: What to Know. A new study finds that people who had COVID-19 are at increased risk for blood disorders months after their illness.
This may be due to inflammation from the illness.
Getting vaccinated can help protect people from developing blood clots or bleeding disorders after COVID-19. HealthLine. 6.4.2022. https://www.healthline.com/health-news/covid-19-linked-to-increased-risk-of-blood-clots-even-months-later-what-to-know

Post COVID-19 pulmonary fibrosis; a meta-analysis study. Ann Med Surg. 6.4.2022. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983072/

FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation. Nature. 8.4.2022. https://www.nature.com/articles/s41586-022-04702-4

Why the WHO took two years to say COVID is airborne. Early in the pandemic, the World Health Organization stated that SARS-CoV-2 was not transmitted through the air. That mistake and the prolonged process of correcting it sowed confusion and raises questions about what will happen in the next pandemic. Nature. 6.4.2022. https://www.nature.com/articles/d41586-022-00925-7#:~:text=Early%20in%20the%20pandemic%2C%20the,happen%20in%20the%20next%20pandemic.

What triggers severe COVID? Infected immune cells hold clues. Studies have revealed that infected immune cells prompt a massive inflammatory response. Nature. 6.4.2022. https://www.nature.com/articles/d41586-022-00925-7?

Long Covid-19 may remain a chronic condition for millions. CNN. 6.4.2022. https://edition.cnn.com/2022/04/06/health/long-covid-19-what-it-is/index.html?utm_term=1649773240313cb7d3e794e8f&utm_source=cnn_04.12.22+Results+are+In&utm_medium=email&bt_ee=PEXLei5P3p%2BiG1z4Yln2Auu78mQi6iafOQnIivqIAJmUfotwGi0zJPx41Ek%2Fpfri&bt_ts=1649773240315

Exhaled CO2 as a COVID-19 Infection Risk Proxy for Different Indoor Environments and Activities. National Library of Medicine. (Environ Sci Technol Lett) 5.4.2022. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043197/

Protection by a Fourth Dose of BNT162b2 against Omicron in Israel. NEJM. 5.4.2022. https://www.nejm.org/doi/full/10.1056/NEJMoa2201570?query=recirc_mostViewed_railB_article

Koronapotilaita on kuollut kolmessa kuukaudessa enemmän kuin koko viime vuonna – THL:n Salmisen mukaan keinot suunnan kääntämiseksi ovat vähissä. Lähes kaikki koronavirukseen kuolevat suomalaiset ovat jo valmiiksi sairaita, kertoo johtava asiantuntija Sirkka Goebeler THL:sta. (ei oikein keinoja ole, Mika Salminen THL:stä toteaa, että koronakuolemien määrä alkaa laskea viimeistään kun tapausmäärät lähtevät laskuun). Helsingin Sanomat. 4.4.2022. https://www.hs.fi/kotimaa/art-2000008723113.html

Glasses and risk of COVID-19 transmission – analysis of the Virus Watch Community Cohort study. medRxiv. 4.4.2022. https://www.medrxiv.org/content/medrxiv/early/2022/04/04/2022.03.29.22272997.full.pdf

Bars, cinemas, gyms: Belgium agrees on ‘ventilation plan’ for public places. The Brussels Times. 4.4.2022. https://www.brusselstimes.com/belgium-news/214866/bars-cinemas-gyms-belgium-agrees-on-ventilation-plan-for-public-places?s=03

Cardiac impairment in Long Covid 1-year post-SARS-CoV-2 infection. medRxiv. 4.4.2022. https://www.medrxiv.org/content/10.1101/2022.04.03.22272610v1

Prof Jeremy Nicholson: the link between Long Covid and heart disease. RNZ. 2.4.2022. https://www.rnz.co.nz/national/programmes/saturday/audio/2018836711/prof-jeremy-nicholson-the-link-between-long-covid-and-heart-disease

What Is The Omicron XE Variant And Why Are Scientists Concerned About Its Rapid Transmission Rate? Medriva. 2.4.2022. https://medriva.com/what-is-the-omicron-xe-variant-and-why-are-scientists-concerned-about-their-rapid-transmission-rates-fueling-the-uk/

What Drives Post-COVID Cognitive Changes? — New research hints at why COVID brain fog may persist. Medpage Today. 1.4.2022.  https://www.medpagetoday.com/neurology/generalneurology/97981

Projecting COVID-19 Mortality as States Relax Nonpharmacologic Interventions. JAMA Health Forum. 1.4.2022. https://jamanetwork.com/journals/jama-health-forum/fullarticle/2790812?

Incidence Rates and Clinical Outcomes of SARS-CoV-2 Infection With the Omicron and Delta Variants in Children Younger Than 5 Years in the US. JAMA Pediatrics. 1.4.2022. https://jamanetwork.com/journals/jamapediatrics/fullarticle/2790793?

Analyysi: Korona yhdisti tiedemaailman, Venäjän hyökkäys rikkoi sen jälleen – tieteellä ei ole varaa uuteen kylmään sotaan. Venäjän hallitus on kieltänyt tutkijoitaan osallistumasta kansainvälisiin konferensseihin ja länsimaiset tiedeyhteisöt boikotoivat venäläisiä. Sota on monella alalla katkaissut tutkimuksen, joka luotti yhtenäiseen maailmaan, kirjoittaa toimittaja Johannes Blom. YLE-Uutiset. 1.4.2022. https://yle.fi/uutiset/3-12384327?

April 1 – 10

Diabetes risk rises after COVID, massive study finds
Even mild SARS-CoV-2 infections can amplify a person’s chance of developing diabetes, especially for those already susceptible to the disease. Nature. 31.3.2022. https://www.nature.com/articles/d41586-022-00912-y

How Japan survived covid-19. BMJ. 31.3.2022. https://www.bmj.com/content/376/bmj.o778

Koronakuolemia voitaisiin estää antamalla neljäs annos nopeasti myös alle 80-vuotiaille, sanovat HUSin asiantuntijat. Tehosteannokset olisivat tarpeen erityisesti 70-79-vuotiaiden ikäryhmälle. YLE_Uutiset. 31.3.2022. https://yle.fi/uutiset/3-12384691

SARS-CoV-2 spike protein induces cognitive deficit and anxiety-like behavior in mouse via non-cell autonomous hippocampal neuronal death. Scientific Reports. 31.3.2022. https://www.nature.com/articles/s41598-022-09410-7

Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults. Nature Medicine. 31.3.2022. https://www.nature.com/articles/s41591-022-01780-9

Column: Did Sweden beat the pandemic by refusing to lock down? No, its record is disastrous. Los Angeles Times. 31.3.2022. https://www.latimes.com/business/story/2022-03-31/sweden-covid-policy-was-a-disaster

Diabetes risk rises after COVID, massive study finds. Even mild SARS-CoV-2 infections can amplify a person’s chance of developing diabetes, especially for those already susceptible to the disease. Nature. 31.3.2022.  https://www.nature.com/articles/d41586-022-00912-y?

Can you get Covid twice in one month? How soon you can recatch coronavirus and if you can get Omicron again. Omicron has been shown to typically cause less serious illness, but also brings with it an increased risk of reinfection. iNews/Health. 30.3.2022.  https://inews.co.uk/news/health/covid-can-get-twice-month-how-soon-catch-coronavirus-again-what-reinfection-explained-1443820

Rapid increase in SARS-CoV-2 seroprevalence during the emergence of Omicron variant, Finland. medRxiv. 30.3.2022. https://www.medrxiv.org/content/10.1101/2022.03.25.22272952v1

Omikron säilyy muovipinnalla pidempään kuin muut koronavariantit, jopa 193 tuntia – Myös ihmisiholla se sinnittelee pisimpään. Kaksi tuoretta aasialaista tutkimusta vertailee koronaviruksen omikron-variantin poikkeuksellista kykyä säilyä erilaisilla pinnoilla elossa. Mediuutiset. 30.3.2022. https://www.mediuutiset.fi/uutiset/mu/1c7262b3-4ebd-43b5-bda3-fd9052f4d743?ref=newsletter:65ee&utm_source=uutiskirje%40mediuutiset.fi&utm_medium=email&utm_campaign=MU-Uutiskirje-laakari

Effect of Early Treatment with Ivermectin among Patients with Covid-19. NEJM. 30.3.2022. https://www.nejm.org/doi/full/10.1056/NEJMoa2115869

Asiantuntijat: Korona ei muutu ehkä koskaan tavalliseksi kausi­flunssaksi – tästä se johtuu. Asiantuntijat suhtautuvat epäillen siihen, että koronaviruksesta olisi ainakaan lähiaikoina tulossa ihmisille lievä ja vaaraton tauti. Ilta=sanomat. 30.3.2022. https://www.is.fi/kotimaa/art-2000008714148.html

Older adults can get second coronavirus booster to strengthen waning protection. Washington Post. 29.3.2022. https://www.washingtonpost.com/health/2022/03/29/fda-authorizes-second-booster-shot/

F.D.A. Allows Second Coronavirus Boosters for Everyone 50 and Older
People in the age group can get the additional shot at least four months after their first booster. Those 12 and older with certain immune deficiencies are also eligible. New York Times. 29.3.2022. https://www.nytimes.com/2022/03/29/us/politics/second-coronavirus-booster-shot.html?referringSource=articleShare

White House Reverts to Air Hygiene in latest efforts to thwart coronavirus. It is pushingh strategies, such as better wir filters in schools and businesses, to help thwart the virus. Washingtonm Post. 29.3.2022. https://www.washingtonpost.com/health/2022/03/29/white-house-covid-strategy-indoor-air-quality/

Risk of SARS-CoV-2 reinfections in children: a prospective national surveillance study between January, 2020, and July, 2021, in England. Lancet. 28.3.2022. https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(22)00059-1/fulltext

Molecular consequences of SARS-CoV-2 liver tropism. Nature Metabolism. 28.3.2022. https://www.nature.com/articles/s42255-022-00552-6.

SvD: Förvirring kring Tegnells nya jobb på WHO – jobbet finns inte. HBL. 28.3.2022. https://www.hbl.fi/artikel/forvirring-kring-tegnells-nya-jobb-pa-who-jobbet-finns-inte/?

Huge Study Finds Second COVID-19 Booster is ‘Life-saving’ for Over 60s. Health Policy Watch. 28.3.2022. https://healthpolicy-watch.news/95297-2/

Fourth Vaccine Reduces Risk of Dying From COVID by 78 Percent, Israeli Study Finds. As omicron’s BA.2 variant is fueling a spike in COVID-19 infections, the latest large-scale study by an Israeli HMO suggests that a fourth dose reduces both the risk of infection and severe illness. Haaretz. 26.3.2022. https://www.haaretz.com/israel-news/fourth-vaccine-reduces-risk-of-dying-from-covid-by-78-percent-israeli-study-finds-1.10700268

What to know about flying during the COVID-19 pandemic. Medical News Today. 28.3.2022. https://www.medicalnewstoday.com/articles/flying-during-covid

Fourth Vaccine Reduces Risk of Dying From COVID by 78 Percent, Israeli Study Finds. As omicron’s BA.2 variant is fueling a spike in COVID-19 infections, the latest large-scale study by an Israeli HMO suggests that a fourth dose reduces both the risk of infection and severe illness. Haaretz. 26.3.2022. https://www.haaretz.com/israel-news/fourth-vaccine-reduces-risk-of-dying-from-covid-by-78-percent-israeli-study-finds-1.10700268

SARS-CoV-2 co-infection with influenza viruses, respiratory syncytial virus, or adenoviruses. Lancet. 25.3.2022. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00383-X/fulltext

Can drugs reduce the risk of long COVID? What scientists know so far
Researchers are trying to establish whether existing COVID-19 vaccines and treatments can prevent lasting symptoms. nature. 25.3.2022. https://www.nature.com/articles/d41586-022-00823-y?fbclid=IwAR0rO3bh97jIMiIucaYJHf5yhtOTpWE7vFFDveiEUnT8dZE-CWDSS2FL3Ng

Evusheld (tiksagevimabi/silgavimabi) Yleistiedot Evusheld-valmisteesta sekä siitä, miksi se on hyväksytty EU:ssa (COVID-19 ehkäisylääke). EMA. 25.3.2022. https://www.ema.europa.eu/en/documents/overview/evusheld-epar-medicine-overview_fi.pdf

SARS-CoV-2 infects and replicates in photoreceptor and retinal ganglion cells of human retinal organoids. Stem Cell Reports. 24.3.2022. https://www.cell.com/stem-cell-reports/fulltext/S2213-6711(22)00104-7

Second Booster Vaccine and Covid-19 Mortality in Adults 60 to 100 Years Old. Research Square. 24.3.2022. https://assets.researchsquare.com/files/rs-1478439/v1/24514bba-2c9d-4add-9d8f-321f610ed199.pdf?c=1648141784

Evaluation of airborne transmission risk in university towns based on IEQ surveys. National Library of Medicine. (Energy and Built Environment) 23.3.2022. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942440/

Burden of PCR-Confirmed SARS-CoV-2 Reinfection in the U.S. Veterans Administration, March 2020 – January 2022. medRxiv. 23.3.2022. https://www.medrxiv.org/content/10.1101/2022.03.20.22272571v1.full.pdf

Robust, persistent adaptive immune responses to SARS-CoV-2 in the oropharyngeal lymphoid tissue of children. Research Square. 23.4.2022. https://www.researchsquare.com/article/rs-1276578/v1

Airborne transmission: Are CO2 monitors a long term solution or “pandemic hack?” BMJ. 23.3.2022. https://www.bmj.com/content/376/bmj.o736?

Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 (PIMS-TS): Prospective, national surveillance, United Kingdom and Ireland, 2020. Lancet. 22.3.2022. https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(21)00052-1/fulltext#:~:text=There%20was%20a%20strong%20geographical,SARS%2DCoV%2D2%20antibodies

Evaluation of science advice during the COVID-19 pandemic in Sweden. Nature / Humanities & Sociall Sciences Communications. 22.3.2022.  https://www.nature.com/articles/s41599-022-01097-5

Italian study shows ventilation can cut school COVID cases by 82%. Reuters. 22.3.2022. https://www.reuters.com/world/europe/italian-study-shows-ventilation-can-cut-school-covid-cases-by-82-2022-03-22/

Effectiveness of a second BNT162b2 booster vaccine against hospitalization and death from COVID-19 in adults aged over 60 years. Nature Medicine. 22.3.2022. https://www.nature.com/articles/s41591-022-01832-0_reference.pdf

 

Myocarditis and pericarditis after COVID-19 vaccination: clinical management guidance for healthcare professionals. Gov.UK. 21.3.2022. https://www.gov.uk/government/publications/myocarditis-and-pericarditis-after-covid-19-vaccination/myocarditis-and-pericarditis-after-covid-19-vaccination-guidance-for-healthcare-professionals

March 21-31

Ivermectin Didn’t Reduce Covid-19 Hospitalizations in Largest Trial to Date
Patients who got the antiparasitic drug didn’t fare better than those who received a placebo. Wall Street Journal. 18.3.2022.  https://www.wsj.com/articles/ivermectin-didnt-reduce-covid-19-hospitalizations-in-largest-trial-to-date-11647601200

Omicron survives longer on some surfaces, studies find. That may help explain why it’s more contagious, but it’s no reason to panic. CNN Health. 18.3.2022. https://edition.cnn.com/2022/03/18/health/omicron-surfaces-studies/index.html?

Infektiolääkäri kirjoitti kriittisen kirjan koronan hoidosta – Rajoitukset aiheuttaneet vakavia terveysongelmia ja taloudellisia tappioita.
Uutuuskirja koronapandemiasta Suomessa: Taudin torjuntakeinot aiheuttaneet vakavia terveydellisiä ja taloudellisia haittoja. Kirjan mukaan paljossa on onnistuttu, mutta pelon lietsominen ja ylimitoitetut rajoitukset ajoittaisine täyssulkuineen ovat aiheuttaneet vakavia terveysongelmia ja taloudellisia tappioita. Mediuutiset. 17.3.2022. https://www.mediuutiset.fi/uutiset/mu/a6ea7482-cf62-4c5e-b245-c63603c7a8f7?

FACT SHEET: Biden Administration Launches Effort to Improve Ventilation and Reduce the Spread of COVID-⁠19 in Buildings. White House. 17.3.2022. https://www.whitehouse.gov/briefing-room/statements-releases/2022/03/17/fact-sheet-biden-administration-launches-effort-to-improve-ventilation-and-reduce-the-spread-of-covid-19-in-buildings/

‘Heartbreaking’: How long COVID is impacting children. Global News. 17.3.2022.  https://globalnews.ca/news/8688590/long-covid-symptoms-children/

America Is Zooming Through the Pandemic Panic-Neglect Cycle. All epidemics trigger the same Sisyphean cycle of panic and neglect. Even so, that cycle isn’t meant to spin this quickly. Atlantic. 17.3.2022. https://www.theatlantic.com/health/archive/2022/03/congress-covid-spending-bill/627090/

‘Heartbreaking’: How long COVID is impacting children. Global News. 16.3.2022. https://globalnews.ca/news/8688590/long-covid-symptoms-children/

Global Prevalence of Post COVID-19 Condition or Long COVID: A Meta-Analysis and Systematic Review. J Infect Dis. 16.3.2022. https://pubmed.ncbi.nlm.nih.gov/35429399/  COMPLETE https://watermark.silverchair.com/jiac136.pdf

1 in 4 symptomatic children get long COVID, a new study finds. What are the symptoms? EuroNewsNext. 16.3.2022. https://www.euronews.com/next/2022/03/15/long-covid-has-been-found-in-1-in-4-symptomatic-children-a-new-study-finds-what-are-the-sy

Fevers, convulsions seen more in children during omicron wave: Japan Pediatric Society. The Mainichi. 16.3.2022. https://mainichi.jp/english/articles/20220316/p2a/00m/0na/006000c

Comparative analysis of the risks of hospitalisation and death associated with SARS-CoV-2 omicron (B.1.1.529) and delta (B.1.617.2) variants in England: a cohort study. Lancet. 16.3.2022. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00462-7/fulltext

 

THE COLOR OF CORONAVIRUS:
COVID-19 DEATHS BY RACE AND ETHNICITY IN THE U.S. APM Research Lab. 15.3.2022. https://www.apmresearchlab.org/covid/deaths-by-race

Airborne Transmission of SARS-CoV-2 Delta Variant within Tightly Monitored Isolation Facility, New Zealand (Aotearoa).  Emerging Infectious Diseases. NN.3 2022. https://doi.org/10.3201/eid2803.212318

Fatigue and cognitive impairment in Post-COVID-19 Syndrome: A systematic review and meta-analysis. Brain, Behaviour, and Immunity. NN.3.2022.  https://www.sciencedirect.com/science/article/pii/S0889159121006516

COVID and the Heart: It Spares No One. Research now tells us that COVID doesn’t discriminate when it comes to heart problems. Johns Hopkins. 14.3.2022. https://publichealth.jhu.edu/2022/covid-and-the-heart-it-spares-no-one

Antigenic evolution will lead to new SARS-CoV-2 variants with unpredictable severity. Nature Reviews. Microbiology. 14.3.2022. ttps://www.nature.com/articles/s41579-022-00722-z

Effect of Sotrovimab on Hospitalization or Death Among High-risk Patients With Mild to Moderate COVID-19. A Randomized Clinical Trial. JAMA. 14.3.2022. https://jamanetwork.com/journals/jama/fullarticle/2790246?

Long COVID in Children and Adolescents: A Systematic Review and Meta-analyses. medRxiv. 13.3.2022.  https://www.medrxiv.org/content/10.1101/2022.03.10.22272237v1

One-third of all US child Covid deaths occurred during Omicron surge.
Children seem to be facing increasing risks as mask mandates are abandoned and vaccination rates stall. Guardian. 11.3.2022. https://www.theguardian.com/world/2022/mar/11/us-child-covid-deaths-omicron-surge?CMP=Share_iOSApp_Other

ACE2-independent infection of T lymphocytes by SARS-CoV-2. Nature. 11.3.2022. https://www.nature.com/articles/s41392-022-00919-x

 

March 11-20

We cannot afford to repeat these four pandemic mistakes. BMJ. 10.3.2022. https://www.bmj.com/content/376/bmj.o631

Estimating excess mortality due to the COVID-19 pandemic: a systematic analysis of COVID-19-related mortality, 2020–21. Lancet. 10.3.2022. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)02796-3/fulltext

Mandatory masking in schools reduced COVID-19 cases during Delta surge. NIH-funded study compared more than 1.1 million students across nine states. NIH News Releases. 10.3.2022. https://www.nih.gov/news-events/news-releases/mandatory-masking-schools-reduced-covid-19-cases-during-delta-surge?

Koronan tarttuminen pinnoilta tai lentokoneesta on epätodennäköistä, rauhoittelevat asiantuntijat. Se on aina hyvä muistaa, että normaali elämä ei ole laboratorio. Turun Sanomat. 9.3.2022. https://www.ts.fi/uutiset/4886888

Perspectives: The “Wolf” Is Indeed Coming: Recombinant “Deltacron” SARS-CoV-2 Detected. CCDC Weekly. 9.3.2022. https://weekly.chinacdc.cn/en/article/doi/10.46234/ccdcw2022.054

School Masking Policies and Secondary SARS-CoV-2 Transmission. Pediatrics. 9.3.2022. https://publications.aap.org/pediatrics/article/doi/10.1542/peds.2022-056687/185379/School-Masking-Policies-and-Secondary-SARS-CoV-2

Sveriges statsepidemiolog Anders Tegnell slutar – får jobb hos WHO. Hufvudstadsbladet. 9.3.3033. https://www.hbl.fi/artikel/sveriges-statsepidemiolog-anders-tegnell-slutar-far-jobb-hos-who/

SARS-CoV-2 is associated with changes in brain structure in UK Biobank. Nature.  7.3.2022. https://www.nature.com/articles/s41586-022-04569-5

Aamulehti: Aki Lindén huolissaan koronarokotustahdin hiipumisesta.
Aki Lindén muistuttaa Aamulehdessä, että koronaa on edelleen liikkeellä. Iltalehti. 5.3.2022. https://www.iltalehti.fi/koronavirus/a/a554622b-41ec-4f0d-82ef-f64b7d73bfa8

 

The Challenge of Debunking Health Misinformation in Dynamic Social Media Conversations: Online Randomized Study of Public Masking During COVID-19. J Med Internet Res. 2.3.2022. https://pubmed.ncbi.nlm.nih.gov/35156933/

The White House unveils a new Covid strategy, but it will need congressional funding. NewYork Times. 2.3.2022. https://www.nytimes.com/live/2022/03/02/world/covid-19-tests-cases-vaccine?referringSource=articleShare#biden-announces-initiative-to-pair-coronavirus-tests-with-treatment

How ventilation, filtration, and humidity may prevent coronavirus transmission. Medical News Today. 2.3.2022. https://www.medicalnewstoday.com/articles/how-ventilation-filtration-and-humidity-may-prevent-coronavirus-transmission

Molecular imaging findings on acute and long-term effects of COVID-19 on the brain: A systematic review. JNM. 1.3.2022. https://jnm.snmjournals.org/content/early/2022/02/17/jnumed.121.263085

THL:n Mika Salminen: Koronapandemia on lähestymässä loppuaan – ”Olen optimistinen sen suhteen, että tää oli nyt tässä”. MTV Uutiset. 3.3.2022. https://www.mtvuutiset.fi/artikkeli/thl-n-mika-salminen-koronapandemia-on-lahestymassa-loppuaan-olen-optimistinen-sen-suhteen-etta-taa-oli-nyt-tassa/8368112

March 1 – 10 

Shared Narrative – Analysis on Finnish Socio-Educational Policy and National Broadcasting (YLE) Literacy during COVID-19 Variants 2021. Jyrki Loima. International Journal of Education and Literacy Studies. 28.2.2022. https://www.researchgate.net/publication/358263637_Shared_Narrative_-_Analysis_on_Finnish_Socio-Educational_Policy_and_National_Broadcasting_YLE_Literacy_during_COVID-19_Variants_2021

Koronapandemian alkuperä yhä varmempi: tutkimusten mukaan tartunnat lähtivät eläintorilta kahteen otteeseen, väli-isäntänä saattoi olla supikoira
Kahdessa kansainvälisessä ja yhdessä kiinalaisessa tutkimuksessa on saatu vahvaa näyttöä siitä, että SARS-CoV-2 tarttui torilla myydyistä eläimistä. Hypoteesi laboratoriosta viruksen syntypaikkana hiipuu. YLE Uutiset 28.2.2022. https://yle.fi/uutiset/3-12336380?utm_source=newsletter&utm_medium=email&utm_campaign=scienceweekly&utm_content=2022-03-06

Wuhan market was epicentre of pandemic’s start, studies suggest
Report authors say that the coronavirus SARS-CoV-2 jumped to people from animals sold at the market on two occasions in late 2019 — but some scientists want more definitive evidence. Nature. 27.2.2022. https://www.nature.com/articles/d41586-022-00584-8?

The role of outdoor and indoor air quality in the spread of SARS-CoV-2: Overview and recommendations by the research group on COVID-19 and particulate matter (RESCOP commission). National Library of Medicine. (Environ Res) 26.2.2022. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881809/

Comparative effectiveness of N95, surgical or medical, and non-medical facemasks in protection against respiratory virus infection: A systematic review and network meta-analysis. Wiley Online Library. 26.2.2022. https://onlinelibrary.wiley.com/doi/10.1002/rmv.2336

Protection of Omicron sub-lineage infection against reinfection with another Omicron sub-lineage. medRxiv. 25.2.2922. https://doi.org/10.1101/2022.02.24.22271440

Käännettä parempaan ei koronatilanteessa vielä nähdä – teho-osastolla tilanne oli perjantaina Satakunnassa koko epidemian pahin. Perjantaina hoidossa oli lyhyen ajan jopa viisi koronapotilasta yhtä aikaa. Se on enemmän kuin kertaakaan koko epidemian aikana. Satakunnan kansa. 25.2.2022. https://www.satakunnankansa.fi/koronavirus/art-2000008644315.html

Hus: Kasvo­maski­suositus jatkunee vielä kuukausia. Husin Markku Mäkijärven mukaan suojautuminen koronavirustartuntoja vastaan vain korostuu, kun rajoituksia puretaan ja ihmisten kohtaamiset lisääntyvät. Helsingin Sanomat. 25.2.2022.  https://www.hs.fi/kaupunki/art-2000008636704.html

NIH launches new initiative to study “Long COVID”. The NIH Director. 23.2.2022. https://www.nih.gov/about-nih/who-we-are/nih-director/statements/nih-launches-new-initiative-study-long-covid

Koronatartunnat ovat hidastaneet koronarokotustahtia. Koronarokotuksia annetaan nyt vain kymmenes osa siitä, mitä annettiin vuoden alussa. YLE Uutiset. 23.2.2022. https://yle.fi/uutiset/3-12329829

Coronavirus vaccine protection was much weaker against omicron, data shows. Washington Post. 23.2.2022. https://www.washingtonpost.com/health/interactive/2022/vaccine-omicron-effectiveness/?itid=hp_pandemic

Genomic assessment of quarantine measures to prevent SARS-CoV-2 importation and transmission. Nature Communications. 23.2.2022. https://www.nature.com/articles/s41467-022-28371-z

 

Persisting pulmonary dysfunction in pediatric post-acute Covid-19. medRxiv. 22.2.2022. https://www.medrxiv.org/content/10.1101/2022.02.21.22270909v1

When Finland Decided to Open Up: A Behavioural Scientist’s Perspective. Matti Heino blog. 21.2.2022. https://mattiheino.com/2022/02/21/let-me-be-your-deja-vu/

February 21 – 28

Hemliga dokument avslöjar strategin. Svenska Dagbladet. 20.2.2022.  https://www.svd.se/hemliga-dokument-avslojar-strategin

Opinion: After the pandemic, long covid may unleash a tidal wave of health troubles. Washington Post. 20.2.2022. https://www.washingtonpost.com/opinions/2022/02/20/long-covid-may-unleash-health-troubles-after-pandemic/

How Long Covid Exhausts the Body. New York Times. 19.2.2022. https://www.nytimes.com/interactive/2022/02/19/science/long-covid-causes.html

We’ll Have Herd Immunity by April. Covid cases have dropped 77% in six weeks. Experts should level with the public about the good news. Wall Street Journal. 18.12.2022. https://www.wsj.com/articles/well-have-herd-immunity-by-april-11613669731

Vil at koronasyke barn skal gå på skolen. Barn som kan smitte andre med korona kan være på skolen dersom allmenntilstanden er god. Regjeringen har gjort denne lettelsen i tiltak av hensyn til barn og unge. NRK. 18.2.2022. https://www.nrk.no/norge/vil-at-koronasyke-barn-skal-ga-pa-skolen-1.15857082

Uusi koronatrendi: Lapsipotilaiden määrä sairaaloissa kasvaa Ruotsissa ja Norjassa – tutkimuksen mukaan lapset herkempiä omikronille kuin deltalle
Yhdysvaltalaistutkimuksen mukaan omikroniin sairastuneet lapset joutuivat sairaalahoitoon nelinkertaisesti deltamuunnokseen verrattuna. YLE -Uutiset. 18.2.2022. https://yle.fi/uutiset/3-12322753

Uusi koronatrendi: Lapsipotilaiden määrä sairaaloissa kasvaa Ruotsissa ja Norjassa – tutkimuksen mukaan lapset herkempiä omikronille kuin deltalle
Yhdysvaltalaistutkimuksen mukaan omikroniin sairastuneet lapset joutuivat sairaalahoitoon nelinkertaisesti deltamuunnokseen verrattuna. YLE Uutiset. 18.2.2022. https://yle.fi/uutiset/3-12322753

As BA.2 subvariant of Omicron rises, lab studies point to signs of severity. CNN Health.18.2.2022.  https://edition.cnn.com/2022/02/17/health/ba-2-covid-severity/index.html

Waning 2-Dose and 3-Dose Effectiveness of mRNA Vaccines Against COVID-19–Associated Emergency Department and Urgent Care Encounters and Hospitalizations Among Adults During Periods of Delta and Omicron Variant Predominance — VISION Network, 10 States, August 2021–January 2022. CDC MMWR. 18.2.2022. https://www.cdc.gov/mmwr/volumes/71/wr/mm7107e2.htm?s_cid=mm7107e2_w

’I’m an Olympic Athlete. Due to Long COVID, Now I Struggle to Walk Up a Flight of Stairs’. For COVID-19 long haulers, recovery is slow. New research may, however, explain their suffering and point to new avenues for treatment. Everyday Health. 18.2.2022. https://www.everydayhealth.com/coronavirus/mitochondrial-dysfunction-may-be-to-blame-in-long-covid-19/

Estimates of SARS-CoV-2 Omicron Variant Severity in Ontario, Canada. JAMA. 17.2.2022. https://jamanetwork.com/journals/jama/fullarticle/2789408?

US has suffered more than 1m excess deaths during pandemic, CDC finds
The latest statistic hints at the breadth of Covid-19’s impact on health in the United States. Guardian 17.2.2022. https://www.theguardian.com/world/2022/feb/17/us-excess-deaths-pandemic-cdc

Estimates of SARS-CoV-2 Omicron Variant Severity in Ontario, Canada. JAMA. 17.2.2022. https://jamanetwork.com/journals/jama/fullarticle/2789408

Do masks really harm kids? Here’s what the science says. As more states drop mask mandates, experts explain why keeping them on in schools is still a smart move for families and teachers. National Geographic 17.2.2022. https://www.nationalgeographic.com/science/article/do-masks-really-harm-kids-heres-what-the-science-says

Koronavirustippoja laitettiin vapaaehtoisten nenään – tulokset yllättivät. Miksi toiset ovat alttiimpia tartunnalle kuin toiset, ihmettelevät tutkijat. Ilta=sanomat. 17.2.2022. https://www.is.fi/kotimaa/art-2000008620645.html

Grafiikat näyttävät selkeän käänteen epidemian vaarallisuudessa tammi­kuussa – katso oman ikä­ryhmäsi tiedot. Vaikka tartuntojen ilmaantuvuus moninkertaistui tammikuussa, kuolemien ilmaantuvuus jopa laski joissain ryhmissä, selviää THL:n uusista tiedoista. Helsingin Sanomat. 17.2.2022. https://www.hs.fi/kotimaa/art-2000008617430.html?

STM:n ja THL:n tilannekatsaus koronavirustílanteesta. Valtioneuvosto. 17.2.2022. https://stm.fi/documents/1271139/110045675/STM+THL+VM+mediainfo17.2.22.FINAL.pdf/

Pandemics disable people — the history lesson that policymakers ignore
Influenza, polio and more have shown that infections can change lives even decades later. Why the complacency over possible long-term effects of COVID-19?. Nature. 16.2.2022. https://www.nature.com/articles/d41586-022-00414-x?

Risks of mental health outcomes in people with covid-19: cohort study. BMJ. 16.2.2022. https://www.bmj.com/content/376/bmj-2021-068993?

Mask Effectiveness for Preventing Secondary Cases of COVID-19, Johnson County, Iowa, USA. CDC Emerging Infectious Diseases, nn.1.2022. https://wwwnc.cdc.gov/eid/article/28/1/21-1591_article

Increased Potency and Breadth of SARS-CoV-2 Neutralizing Antibodies After a Third mRNA Vaccine Dose. bioRxiv. 15.2.2022. https://www.biorxiv.org/content/10.1101/2022.02.14.480394v1

”Det mest anständiga är att åtalet läggs ner”. Jag var en av dem som erbjöds förmånen att bli testad, skriver Sven Britton, professor emeritus, om att åtal väckts för en testning för bestämning av antikroppar mot sars-cov-2. (1 kommentar). Dagens Medicin. 15.2.2022. https://www.dagensmedicin.se/opinion/debatt/det-mest-anstandiga-ar-att-atalet-laggs-ner/

Persistent SARS-CoV-2 Nucleocapsid Protein Presence in the Intestinal Epithelium of a Pediatric Patient 3 Months After Acute Infection. JPGN Reports. nn.2.2022. https://journals.lww.com/jpgnr/fulltext/2022/02000/persistent_sars_cov_2_nucleocapsid_protein.9.aspx

Ilmahygienia suojaa koronatartunnoilta. Ilmavälitteisen tartunnan riskiä voidaan vähentää tieteen ja teknologian tuomien ratkaisujen avulla. Lääkärilehti. 14.2.2022. https://www.laakarilehti.fi/kliininen-tyo/ilmahygienia-suojaa-koronatartunnoilta/?public=c118ba0e51b2a0f8429a4b19c5e7a7df

CDC: COVID-19 Booster Effectiveness Wanes After Four Months.
The agency also finds that third shots prevented hospitalizations during the Omicron wave.The Scientist. 14.2.2022. https://www.the-scientist.com/news-opinion/cdc-covid-19-booster-effectiveness-wanes-after-four-months-69703?

FEATURE: Reduced brain function, immune disorder a possibility of ”long COVID”. Kyodo News. 14.2.2022. https://english.kyodonews.net/news/2022/02/263518f1cd8b-feature-reduced-brain-function-immune-disorder-a-possibility-of-long-covid.html

Persistence, prevalence, and polymorphism of sequelae after COVID-19 in young adults. [testosterone] medRxiv. 13.2.2022. https://doi.org/10.1101/2022.02.11.22270836

Tutkijat varoittavat pandemian jälkeisestä sydänpommista: Riskit koholla vielä vuosi infektion jälkeen. MTV-Uutiset 12.2.2021. https://www.msn.com/fi-fi/terveysjafitness/hyvinvointi/tutkijat-varoittavat-pandemian-j%C3%A4lkeisest%C3%A4-syd%C3%A4npommista-riskit-koholla-viel%C3%A4-vuosi-infektion-j%C3%A4lkeen/ar-AATJ1uJ?ocid=winp-sf

Effectiveness of Face Mask or Respirator Use in Indoor Public Settings for Prevention of SARS-CoV-2 Infection — California, February–December 2021. CDC MMWR. 11.2.2022. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830622/

Desinfioivaa UV-valaistusta voidaan käyttää myös ihmisten läsnä ollessa. Covid-19-pandemia on vauhdittanut UV-valoon perustuvan desinfiointiteknologian kehitystä ja käyttöönottoa. Mediuutiset. 11.2.2022. https://www.mediuutiset.fi/uutiset/mu/50a72e39-7b3c-402b-8d5a-92170a0ebcc5?

Academics: Viral Evolution Scenarios, 10 February 2022. Gov.UK. 11.2.2022. https://www.gov.uk/government/publications/academics-viral-evolution-scenarios-10-february-2022

THL: Koronastrategiaan muutos – Neljäs annos ensisijaisesti vain riskiryhmille. Neljäs rokoteannos ei toisi merkittävää lisähyötyä koko väestölle. Suoja vakavalta taudilta säilyy hyvänä kolmannen annoksen jälkeen myös omikrontartunnoissa. Sosiaali- ja terveydenhuollon henkilöstön rokotukset ovat yhä lääketieteellisesti perusteltuja. Mediuutiset. 11.2.2022. https://www.mediuutiset.fi/uutiset/thl-koronastrategiaan-muutos-neljas-annos-ensisijaisesti-vain-riskiryhmille/c1ff347d-76fc-40c8-b79b-e11ea5bcf9db

February 11 – 20

Trial By Error: My Exchange of Letters on Amygdala Retraining; That Undead Lightning Process Study (Helena Kiira, Long COVID papper critique) Virology Blog. 10.2.2022. https://www.virology.ws/2022/02/10/trial-by-error-my-exchange-of-letters-on-amygdala-retraining-that-undead-lightning-process-study/

Weekly death statistics [31 European Countries]. Eurostat. 10.2.2021.  https://ec.europa.eu/eurostat/statistics-explained/index.php?title=Weekly_death_statistics#Data_sources

Heart-disease risk soars after COVID — even with a mild case
Massive study shows a long-term, substantial rise in risk of cardiovascular disease, including heart attack and stroke, after a SARS-CoV-2 infection. Nature. 10.2.2022. https://www.nature.com/articles/d41586-022-00403-0

Risk of persistent and new clinical sequelae among adults aged 65 years and older during the post-acute phase of SARS-CoV-2 infection: retrospective cohort study. BMJ. 9.2.2022. https://www.bmj.com/content/376/bmj-2021-068414

Omicron Has Been Found in Deer—That Should Worry Us. TIME. 9.2.2022. https://time.com/6146253/omicron-deer-covid-19/

Perspective SARS-CoV-2 infections in children: Understanding diverse outcomes. Immunity (Cell). 8.2.2022. https://www.cell.com/action/showPdf?pii=S1074-7613%2822%2900043-7

Tyypin 1 diabetes on lisääntynyt korona-aikana Helsingissäkin. Syy on epäselvä ja vaatii lisätutkimuksia, mutta koronapandemiaan on ajallinen yhteys. Lääkärilehti. 8.2.2022. https://www.laakarilehti.fi/tieteessa/tyypin-1-diabetes-on-lisaantynyt-korona-aikana-helsingissakin/?

Long-term cardiovascular outcomes of COVID-19. Nature Medicine. 7.2.2022. https://www.nature.com/articles/s41591-022-01689-3

Host genomes for the unique SARS-CoV-2 variant leaked into Antarctic soil metagenomic sequencing data. Research Square. 7.2.2022. https://www.researchsquare.com/article/rs-1330800/v1

Antihistamines for Postacute Sequelae of SARS-CoV-2 Infection. The Journal for Nurse Practitioners. 7.2.2022. https://www.sciencedirect.com/science/article/pii/S155541552100547X

Rapid and ultrasensitive electromechanical detection of ions, biomolecules and SARS-CoV-2 RNA in unamplified samples, Nature Biomedical Engineering. 7.2.2022. https://www.nature.com/articles/s41551-021-00833-7?

Long-term cardiovascular outcomes of COVID-19. Nature Medicine. 7.2.2022. https://www.nature.com/articles/s41591-022-01689-3

Päivittyvä seuranta: Sairaanhoitopiirit tyrmäävät koululaisten säännöllisen kotitestauksen | Australia avaa rajansa helmikuun lopulla | Turkin presidentillä koronatartunta
Kerromme uusimmat tiedot koronaviruksesta tässä artikkelissa. YLE-Uutiset. 7.2.2022. https://yle.fi/uutiset/3-11942036?utm_source=social-media-share&utm_medium=social&utm_campaign=ylefiapp

Brief incubation, high viral shedding: COVID-19 human challenge trial results. Medical News Today. 4.2.2022. https://www.medicalnewstoday.com/articles/brief-incubation-high-viral-shedding-covid-19-human-challenge-trial-results?

Effectiveness of Face Mask or Respirator Use in Indoor Public Settings for Prevention of SARS-CoV-2 Infection — California, February–December 2021. CDC Morbidity and Mortality Weekly Report. 4.2.2022. https://www.cdc.gov/mmwr/volumes/71/wr/mm7106e1.htm

Alzheimer’s-like changes found in COVID patients’ brains; flu shot, mRNA booster safe together. Reuters. 4.2.2022. https://www.reuters.com/business/healthcare-pharmaceuticals/alzheimers-like-changes-found-covid-patients-brains-flu-shot-mrna-booster-safe-2022-02-04/

How a nondescript box has been saving lives during the pandemic – and revealing the power of grassroots innovation. The Conversation 3.2.2022. https://theconversation.com/how-a-nondescript-box-has-been-saving-lives-during-the-pandemic-and-revealing-the-power-of-grassroots-innovation-176779?

Complications Following SARS-CoV-2 Infection in Victoria, Australia: A Record Linkage Study. SSRN (Lancet). 3.2.2022. https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4025054

SARS-CoV-2 Infections in Close Contacts of Positive Cases in the Olympic and Paralympic Village at the 2021 Tokyo Olympic and Paralympic Games. JAMA. 3.2.2022. https://jamanetwork.com/journals/jama/fullarticle/2788895?

Pre-infection 25-hydroxyvitamin D3 levels and association with severity of COVID-19 illness. OLOS One. 3.2.2022. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0263069

Tutkimus: Koronavirus voi tarttua yhdestä pisarasta. Tutkijoiden mukaan kokeiden perusteella tehtiin rohkaisevia havaintoja. Iltalehti. 3.2.2022. [ep’äeettinen tutkimus] https://www.iltalehti.fi/ulkomaat/a/4db7f55f-75d2-401b-9fab-bed077f38095

Prevalence of ongoing symptoms following coronavirus (COVID-19) infection in the UK. ONS. 3.2.2021. https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/datasets/alldatarelatingtoprevalenceofongoingsymptomsfollowingcoronaviruscovid19infectionintheuk?s=09

Miksi rajoituksia puretaan, vaikka korona­kuolemia kirjataan yhä kymmeniä viikossa? – ”Ei voida ajatella, että kukaan ei saa Suomessa koskaan kuolla mihinkään”, sanoo THL:n Salminen. Yhä pienempi osa koronatartunnan saaneista kuolee tautiin. Aamulehti. 2.2.2022. https://www.aamulehti.fi/koronavirus/art-2000008583714.html

Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge. [Alexander van Assendelft: an unethical human experiment] Research Square. 1.2.2022. https://www.researchsquare.com/article/rs-1121993/v1

Model-Estimated Association Between Simulated US Elementary School-Related SARS-CoV-2 Transmission, Mitigation Interventions, and Vaccine Coverage Across Local Incidence Levels. JAMA. 1.2.2022. https://pubmed.ncbi.nlm.nih.gov/35157056/

Moni uskoo, että Suomessa on tiukemmat koronarajoitukset kuin muualla – tarkistimme faktat, ja asia on lähes päinvastoin. Tämä juttu kertoo, miten Suomen tämänhetkiset rajoitukset vertautuvat Tanskaan, Saksaan, Englantiin ja Italiaan. Tällä hetkellä yhteiskuntaa avataan osassa Euroopan maita Suomea rivakammin. YLE-Uutiset. 1.2.2022. https://yle.fi/uutiset/3-12297246?utm_source=newsletter&utm_medium=email&utm_campaign=newsdaily&utm_content=2022-02-02

Koronakuolemien määrä kasvaa nopeasti – kysyimme, miksi THL laskee lukuihin muitakin kuin selkeitä koronataudin aiheuttamia kuolemia. Koronaan liittyvien kuolemien määrä ylittää pian 2 000:n rajapyykin. Suurin kuolleisuus on iäkkäillä rokottamattomilla. THL kirjaa koronakuolemiksi kuolemat, jotka ovat tapahtuneet 30 vuorokauden aikana tartunnasta. YLE-Uutiset. 1.2.2022. https://yle.fi/uutiset/3-12296560?utm_source=newsletter&utm_medium=email&utm_campaign=newsdaily&utm_content=2022-02-02

High Rates of Rapid Antigen Test Positivity After 5 days of Isolation for COVID-19. medRxiv. 1.2.2022. https://www.medrxiv.org/content/10.1101/2022.02.01.22269931v1.full.pdf

Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge. In Review.1.2.2022. https://www.researchsquare.com/article/rs-1121993/v1

February 1 – 10

It’s a delusion to think mass spread of Omicron will end the pandemic.Globe and Mail. 31.1.2022. https://www.theglobeandmail.com/opinion/article-its-a-delusion-to-think-mass-spread-of-omicron-will-end-the-pandemic/

Transmission of SARS-CoV-2 Omicron VOC subvariants BA.1 and BA.2: Evidence from Danish Households. medRxiv. 30.1.2022. https://www.medrxiv.org/content/10.1101/2022.01.28.22270044v1.full

Russia Sees Record Population Decline As Excess Deaths Hit 1M. Russia experienced its largest population decline in 2021 since the end of the Soviet Union. Moscow Times. 29.1.2022. https://www.themoscowtimes.com/2022/01/28/russias-pandemic-excess-death-toll-almost-1m-a76194

37,000 People Already Received 4th Vaccination in Hungary. Hungary today. 28.1.2022. https://hungarytoday.hu/coronavirus-covid-19-vaccines-fourth-dose-jab-booster/

Covid-19: Antibody “signature” could predict risk of long covid. BMJ. 28.1.2022. https://www.bmj.com/content/376/bmj.o245?

The COVID Project: Coronavirus in Kids Tracking and Education Project. 28.1.2022. https://www.covkidproject.org/

Nämä keinot ovat vanhentuneet koronan torjunnassa, professori sanoo – tässä pätevät
Moni lotraa edelleen käsidesin kanssa, vaikka oleellisempaa omikronin leviämisen ehkäisemisessä olisi maskin käyttäminen oikein. Iltalehti. 28.1.2022. https://www.iltalehti.fi/terveysuutiset/a/4beeae55-439a-4367-8762-24239d61be4a?

Coronaviruset hänger ofta kvar i inomhusluften – forskare uppmanar oss att vrida upp luftkonditioneringen och att använda luftrenare. Svenska YLE. 28.1.2022. https://svenska.yle.fi/a/7-10012085

Läkare med postcovid: Jag saknar den jag var. Detta är min berättelse om postcovid och den är varken unik eller allmängiltig, skriver läkaren Lisa Norén som har postcovid och är aktiv i nätverket Läkare till läkare. Hon tar upp Hanne Kjöllers uppmärksammade artiklar om postcovid och avfärdar att det är en kultursjukdom. Hon menar att sjukdomen är komplex och därför krävs det läkare med postcovidkompetens. Kvartal. 27.1.2022. https://kvartal.se/artiklar/lakare-med-postcovid-jag-saknar-den-jag-var/

THL:n Mika Salminen pohjoiselle valmiustoimikunnalle: Alueelliset toimijat ovat onnistuneet torjumaan koronaa hyvin. Pohjois-Suomen alueellinen valmiustoimikunta kokoontui alkuviikolla uudistuneessa kokoonpanossa ylijohtaja Terttu Savolaisen johdolla. Asiantuntijavieraana oli THL:n terveysturvallisuusosaston johtaja, professori Mika Salminen, joka kiitti alueellisia toimijoita erinomaisesta onnistumisesta koronapandemian torjunnassa. Mun Oulu. 27.1.2022. https://www.munoulu.fi/artikkeli/-/id/thl-n-mika-salminen-pohjoiselle-valmiustoimikunnalle-alueelliset-toimijat-ovat-onnistuneet-torjumaan-koronaa-hyvin

Uusi normaali koittaa kesään mennessä, sanoo THL:n Mika Salminen – tätä se tarkoittaa. Kaikki merkit viittaavat siihen, että uusi normaali on kulman takana: se tarkoittaa ensi kesänä suurten ja perinteisten kesäfestivaalien paluuta. Iltalehti. 27.1.2022. https://www.iltalehti.fi/koronavirus/a/cd4b87e6-19e4-4f0e-8603-5b4f727c372a

Asiantuntijan mukaan olemme koronapandemian loppuvaiheilla, mutta sinänsä korona ei koskaan lopu. Koronapandemia päättyy eri paikoissa eri aikaan, mutta epidemiologi Jussi Sanen mukaan pandemiassa ollaan jo loppuvaiheilla. HUSin apulaisylilääkäri Eeva Ruotsalainen ei kuitenkaan halua olla ylioptimistinen.YLE-Uutiset. 27.1.2022. https://yle.fi/uutiset/3-12288922?

COVID-19 vaccine surveillance report. Week 4. UK Health Security Agency. 27.1.2022. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1050721/Vaccine-surveillance-report-week-4.pdf

Turkulainen hammastahna-suuvesi covid-19-infektiota vastaan sai patentin Yhdysvalloissa.
Yhtiön mukaan koronaa vastaan toimiva hammastahna-suuvesi perustuu elimistön oman kemiallisen puolustusmekanismin vahvistamiseen. Mediuutiset. 27.1.2022. https://www.mediuutiset.fi/uutiset/mu/8f2511e1-86f7-499e-8195-d9c95ea05583?

The Covid Resilience Ranking. The Best and Worst Places to Be as We Learn to Live With Covid. Bloomberg. 27.1.2022. https://www.bloomberg.com/graphics/covid-resilience-ranking/?

Implication of COVID-19 on Erythrocytes Functionality: Red Blood Cell Biochemical Implications and Morpho-Functional Aspects. Int J Mol Sci. 27.1.2022. https://www.mdpi.com/1422-0067/23/4/2171/htm

A second version of omicron is spreading. Here’s why scientists are on alert. NPR. 27.1.2022. https://www.npr.org/sections/goatsandsoda/2022/01/27/1076123109/new-covid-variant-omicron-ba-2

Satasairaalan henkilöstöllä todettu runsaasti koronatartuntoja – Leikkauksia joudutaan perumaan. Kiireelliset toimenpiteet ja päivystysleikkaukset toteutetaan poikkeustilanteesta huolimatta normaalisti. Satakunnan Kansa. 26.1.2022.  https://www.satakunnankansa.fi/koronainfo/art-2000008569067.html

Neutralizing immunity in vaccine breakthrough infections from the SARS-CoV-2 Omicron and Delta 2 variants. medRxiv. 26.1.2022. https://www.medrxiv.org/content/10.1101/2022.01.25.22269794v1.full.pdf

When will the COVID-19 pandemic end? 4 essential reads on past pandemics and what the future could bring. The Conversation. 26.1.2022. https://theconversation.com/when-will-the-covid-19-pandemic-end-4-essential-reads-on-past-pandemics-and-what-the-future-could-bring-175587?

Alueelliset toimijat ovat onnistuneet torjumaan koronaa, totesi Mika Salminen Pohjois-Suomen alueellisessa valmiustoimikunnassa.
Pohjois-Suomen alueellinen valmiustoimikunta kokoontui 25.1.2022 uudistuneessa kokoonpanossa ylijohtaja Terttu Savolaisen johdolla. Asiantuntijavieraana oli Terveyden ja hyvinvoinnin laitoksen terveysturvallisuusosaston johtaja, professori Mika Salminen, joka kiitti alueellisia toimijoita erinomaisesta onnistumisesta koronapandemian torjunnassa. Aluehallintovirasto. 25.1.2022. https://www.sttinfo.fi/tiedote/alueelliset-toimijat-ovat-onnistuneet-torjumaan-koronaa-totesi-mika-salminen-pohjois-suomen-alueellisessa-valmiustoimikunnassa?publisherId=69818103&releaseId=69930577

The Real-time Assessment of Community Transmission (REACT) programme is one of the largest, most significant pieces of research looking at how the COVID-19 pandemic is progressing in England. Imperial College. 25.1.2022. https://www.imperial.ac.uk/medicine/research-and-impact/groups/react-study/real-time-assessment-of-community-transmission-findings/

The study is being carried out by a world-class team of scientists, clinicians and researchers at Imperial College London, in partnership with Ipsos MORI, and was commissioned by the Department of Health and Social Care. Explore our study’s findings below.

Neutralizing immunity in vaccine breakthrough infections from the SARS-CoV-2 Omicron and Delta variants. medRxiv. 25.1.2022. https://www.medrxiv.org/content/10.1101/2022.01.25.22269794v1.full.pdf

Close relatives of MERS-CoV in bats use ACE2 as their functional receptors, bioRxiv.25.1.2022. https://www.biorxiv.org/content/10.1101/2022.01.24.477490v1.full.pdf

COVID-19: endemic doesn’t mean harmless. Rosy assumptions endanger public health — policymakers must act now to shape the years to come. Nature. 24.1.2022. https://www.nature.com/articles/d41586-022-00155-x

Parties may lead to his downfall, but is this the worst of what Johnson has done? BMJ. 24.1.2022. https://www.bmj.com/content/376/bmj.o196?

Disease severity during SARS-COV-2 reinfection: a nationwide study. J of Infection. 24.1.2022. https://www.journalofinfection.com/article/S0163-4453(22)00010-X/fulltext

COVID-19: endemic doesn’t mean harmless. Rosy assumptions endanger public health — policymakers must act now to shape the years to come. Nature. 24.1.2022. https://www.nature.com/articles/d41586-022-00155-x

T cell apoptosis characterizes severe Covid-19 disease. Cell death and differentiation. 22.1.2022. https://www.nature.com/articles/s41418-022-00936-x

Functional evaluation of the P681H mutation on the proteolytic activation of the SARS-CoV-2 variant B.1.1.7 (Alpha) spike. iScience. 21.1.2022. https://www.sciencedirect.com/science/article/pii/S2589004221015595?

“Hengitysilma paremmaksi ja FFP2-maskit kasvoille” – fysiikka ei erehdy, koronan torjunnassa on otettava uusi askel. Pandemian alkuvaiheessa monet asiantuntijat ja poliitikot uskoivat vahvasti myyttiin, etteivät virukset leviä ensisijaisesti hengitysilmassa vaan kosketustartunnan kautta. Fyysikot toivat kuitenkin jo pandemian alkuvaiheessa esille, että korona leviää voimakkaimmin nimenomaan hengitysilmassa. Virusta täytyykin jatkossa torjua rokotusten ohella ennen kaikkea hengitysilman laatuun keskittymällä, kirjoittaa apulaisprofessori Ville Vuorinen. MustRead. 21.1.2022. https://www.mustread.fi/artikkelit/hengitysilma-paremmaksi-ja-ffp2-maskit-kasvoille-fysiikka-ei-erehdy-koronan-torjunnassa-on-otettava-uusi-askel/?

Ville Vuorinen: Hengitysilman parantaminen on avain pandemian torjuntaan. Korona leviää ilmateitse, ja siksi sitä ei pysäytetä käsien pesulla, sanoo apulaisprofessori Ville Vuorinen. Paukut pitäisi pistää ilmahygieniaan, ja siinä tarvitaan sekä tehokasta ilmanvaihtoa että oikeanlaisia maskeja.  A” Uutiset 21.1.2022. https://www.aalto.fi/fi/uutiset/ville-vuorinen-hengitysilman-parantaminen-on-avain-pandemian-torjuntaan

January 21 – 31

Rapid vigilance and episodic memory decrements in COVID-19 survivors. Brain Communications. 19.1.2022. https://academic.oup.com/braincomms/article/4/1/fcab295/6511053?login=false

Ilmanvaihto-ohjeistus varhaiskasvatuksen, opetuksen ja koulutuksen tilojen käytöstä vastaaville. THL. 19.1.2021. https://thl.fi/fi/web/ymparistoterveys/sisailma/koronavirus-ja-sisailman-turvallisuus/ilmanvaihto-ohjeistus-varhaiskasvatuksen-opetuksen-ja-koulutuksen-tilojen-kaytosta-vastaaville

Differences in environmental stability among SARS-CoV-2 variants of concern: Omicron has higher stability. bioRxiv. 19.1.2022. https://www.biorxiv.org/content/10.1101/2022.01.18.476607v1.full

SARS-CoV-2 breakthrough infections elicit potent, broad, and durable neutralizing antibody responses. Cell. 19.1.2022. https://www.cell.com/cell/fulltext/S0092-8674(22)00069-1#relatedArticles

Biden Will Give Away Free N95 Masks at Pharmacies and Health Centers. TIME. 19.1.2022. https://time.com/6140223/biden-free-n95-masks/?utm_medium=email&utm_source=sfmc&utm_campaign=newsletter+coronavirus+default+ac&utm_content=+++20220119+++body&et_rid=149179605&lctg=149179605

Respiratory viruses that hijack immune mechanisms may have Achilles’ heel. Phys.org. 18.1.2022. https://phys.org/news/2022-01-respiratory-viruses-hijack-immune-mechanisms.html

Incidence of Type 1 Diabetes in Children and Adolescents During the COVID-19 Pandemic in Germany: Results From the DPV Registry. Diabetes Care. 17.1.2022. https://diabetesjournals.org/care/article-abstract/doi/10.2337/dc21-0969/139385/Incidence-of-Type-1-Diabetes-in-Children-and?redirectedFrom=fulltext

Israel Finds Fourth COVID Booster is only ‘Partially Effective,’ Vast Majority of Hospitalised Omicron Patients Are Unvaccinated.  Health Policy Watch. 17.1.2022. https://healthpolicy-watch.news/israel-fourth-covid-booster-ineffective/

Tamperelaisyritys sai luvan koronakeksinnölleen: puhallustesteri antaa alle minuutissa tiedon koronatartunnasta. Suomessa kehitetty puhallustesteri mittaa uloshengityksestä koronainfektion aiheuttamia yhdisteitä. YLE-Uutiset. 17.1.2022. https://yle.fi/uutiset/3-12273307?

Kannanotto: Valmiuslaki ei takaa terveydenhuollon kantokykyä. Nuorten Lääkärien Yhdistys. 17.1.2022. https://www.nly.fi/kannanotto-valmiuslaki-ei-takaa-terveydenhuollon-kantokykya/

Hen­gi­tys­suo­jai­met toi­mi­vat, vaikka jotkut muuta väit­tä­vät­kin [Ari Laaksonen]. Kaleva. 16.1.2022.  https://www.kaleva.fi/hengityssuojaimet-toimivat-vaikka-jotkut-muuta-vai/4249701

Excess mortality in 2020-2021 % change compared with 2016-2019 average. Eurostat Statistics explained. nn.1.2022. https://ec.europa.eu/eurostat/statistics-explained/index.php?title=File:Excess_Mortality_Update_DEC2021GIF.gif

Risk factors and disease profile of post-vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: a prospective, community-based, nested, case-control study. Lancet Infectious Diseases. NN.1.2022. https://www.sciencedirect.com/science/article/pii/S1473309921004606

With COVID-19, Air Is Both the Problem and the Solution. SARS-CoV-2 can linger in the air. Dealing with it can be relatively easy, but first, we have to admit we have a problem McGill. 15.1.2022. https://www.mcgill.ca/oss/article/covid-19/covid-19-air-both-problem-and-solution

One in nine recent virus cases in Israel are reinfections — report. High proportion of those who recovered and were then reinfected were at least partially vaccinated; officials believe confirmed daily cases will reach 100,000 in coming days. Times of Israel. 15.1.2022. https://www.timesofisrael.com/one-in-nine-recent-virus-cases-in-israel-are-reinfections-report/

A LITERATURE REVIEW AND META-ANALYSIS OF THE EFFECTS OF LOCKDOWNS ON COVID-19 MORTALITY. Studies in Applied Economics. NN.1.2022. extension://elhekieabhbkpmcefcoobjddigjcaadp/https://sites.krieger.jhu.edu/iae/files/2022/01/A-Literature-Review-and-Meta-Analysis-of-the-Effects-of-Lockdowns-on-COVID-19-Mortality.pdf

Risk for Newly Diagnosed Diabetes >30 Days After SARS-CoV-2 Infection Among Persons Aged <18 Years — United States, March 1, 2020–June 28, 2021. CDC. 14.1.2022. https://www.cdc.gov/mmwr/volumes/71/wr/mm7102e2.htm

Weekly epidemiological update: Omicron variant of concern (VOC) – week 2 (data as of 13 January 2022) EU/EEA. ECDC. 14.1.2022. https://www.ecdc.europa.eu/en/news-events/weekly-epidemiological-update-omicron-variant-concern-voc-week-2-data-13-january-2022

COVID-19 starkly increases pregnancy complications, including stillbirths, among the unvaccinated, Scottish study shows. Separate study finds timing of infection during pregnancy predicts prematurity. Science. 14.1.2022. https://www.science.org/content/article/covid-19-starkly-increases-pregnancy-complications-including-stillbirths-among?

Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection. nature immunology. 13.1.2022. https://www.nature.com/articles/s41590-021-01113-x

Covid-19: Peak of viral shedding is later with omicron variant, Japanese data suggest. BMJ. 13.1.2022. https://www.bmj.com/content/376/bmj.o89

Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection. Nature Immunology. 13.1.2022. https://www.nature.com/articles/s41590-021-01113-x?

Comparison of serum neurodegenerative biomarkers among hospitalized COVID-19 patients versus non-COVID subjects with normal cognition, mild cognitive impairment, or Alzheimer’s dementia. Alzheimer’s Association. 13.1.2022. https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.12556

Covid-19: Peak of viral shedding is later with omicron variant, Japanese data suggest. BMJ. 13.1.2022. https://www.bmj.com/content/376/bmj.o89

Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection. Nature Immunology. 13.1.2022. https://www.nature.com/articles/s41590-021-01113-x

The effectiveness of vaccination against long COVID. A rapid evidence briefing. UK Health Security Agency. 12.1.2022. https://ukhsa.koha-ptfs.co.uk/cgi-bin/koha/opac-retrieve-file.pl?id=fe4f10cd3cd509fe045ad4f72ae0dfff

Covid-19 control measures and common paediatric infections. BMJ. 12.1.2022.  https://doi.org/10.1136/bmj.n3093

Analyzing natural herd immunity media discourse in the United Kingdom and the United States. [Great Barrington Declaration, False balance in media coverage]. PLOS Global Public Health. 12.1.2022. https://journals.plos.org/globalpublichealth/article?id=10.1371/journal.pgph.0000078

Indirect effects of the covid-19 pandemic on childhood infection in England: population based observational study. BMJ. 12.1.2022. https://doi.org/10.1136/bmj-2021-067519

Slow the Spread? Speeding It May Be Safer. Tamping down on Omicron may increase the risk of an ‘antigenic shift’ to a far deadlier supervariant. Wall Street Journal. 10.1.2022. https://www.wsj.com/articles/speeding-it-may-be-safer-omicron-mandates-antigenic-drift-shift-covid-supervariant-mask-social-distancing-lockdown-vaccine-11641847062

The Dynamics of SARS-CoV-2 Infectivity with Changes in Aerosol. Microenvironment.  medRxiv. 10.1.2022. https://www.medrxiv.org/content/10.1101/2022.01.08.22268944v1.full.pdf

Covid loses 90% of ability to infect within 20 minutes in air – study
Exclusive: Findings highlight importance of short-range Covid transmission. The Guardian. 11.1.2022. https://www.theguardian.com/world/2022/jan/11/covid-loses-90-of-ability-to-infect-within-five-minutes-in-air-study

WHO: Jatkuvissa tehosterokotuksissa ei järkeä
Maailman terveysjärjestön mukaan tarvitaan rokote, joka ehkäisee tartuntoja. Iltalehti. 11.1.2022. https://www.iltalehti.fi/ulkomaat/a/5ca307c8-7c15-4476-a361-b544d3b9e77e?

January 11 – 20 

Slow the Spread? Speeding It May Be Safer. Tamping down on Omicron may increase the risk of an ‘antigenic shift’ to a far deadlier supervariant. WSJ Opinnon. 10.1.2022. https://www.wsj.com/articles/speeding-it-may-be-safer-omicron-mandates-antigenic-drift-shift-covid-supervariant-mask-social-distancing-lockdown-vaccine-11641847062

The Dynamics of SARS-CoV-2 Infectivity with Changes in Aerosol Microenvironment. medRxiv. 10.1.2022.  https://www.medrxiv.org/content/10.1101/2022.01.08.22268944v1

Infectious viral load in unvaccinated and vaccinated patients infected with SARS-CoV-2 WT, Delta and Omicron. MedRxiv. 10.1.2022. https://www.medrxiv.org/content/10.1101/2022.01.10.22269010v1

Liikuntaväki huolissaan lasten harrastusten rajoituksista – THL:n Tervahauta: Hyödyt vähäiset, haitat suuret. Viranomaisten toimia pidetään poukkoilevana ja rajoituskaavailuja epäreiluina lasten ja nuorten kannalta. Lajiliittojen johtajat pelkäävät koko ikäluokan menettämistä. YLE-Uutiset. 8.1.2022. https://yle.fi/uutiset/3-12263002?

Mild respiratory SARS-CoV-2 infection can cause multi-lineage cellular dysregulation and myelin loss in the brain. bioRxiv. 10.1.2022. https://www.biorxiv.org/content/10.1101/2022.01.07.475453v1.full

Hospitals Are in Serious Trouble. Omicron is inundating a health-care system that was already buckling under the cumulative toll of every previous surge. Atlantic. 7.1.2022. https://www.theatlantic.com/health/archive/2022/01/omicron-mild-hospital-strain-health-care-workers/621193/

STM:n asiantuntija­ryhmä: Korona voi ilmetä pitkäkestoisena joka toisella aikuisella – HS seurasi tiedotus­tilaisuutta. Uupumus, hengenahdistus ja kognitiiviset häiriöt yleisiä oireita. Helsingin Sanomat. 7.1.2022. https://www.hs.fi/kotimaa/art-2000008523531.html

Immunity against Omicron from breakthrough infection could be a matter of timing. Laboratory studies hint that a longer interval between vaccination and infection is better than a shorter one. Nature. 7.1.2022.  https://www.nature.com/articles/d41586-022-00004-x?

Risk Factors for Severe COVID-19 Outcomes Among Persons Aged ≥18 Years Who Completed a Primary COVID-19 Vaccination Series — 465 Health Care Facilities, United States, December 2020–October 2021. CDC Morbidity and Mortality Weekly Report. 7.1.2022. https://www.cdc.gov/mmwr/volumes/71/wr/mm7101a4.htm

How to Think About Covid Data Right Now. New York Times. 7.1.2022. https://www.nytimes.com/interactive/2022/01/07/us/covid-data-explained.html

Higher viral load and infectivity increase risk of aerosol transmission for Delta and Omicron variants of SARS-CoV-2. Swiss Medical Weekly. 6.1.2021. https://smw.ch/article/doi/smw.2022.w30133

Virologian professori: Maskien käyttö on nyt tärkeämpää kuin koskaan – Tilanne pääkaupunkiseudulla ”kuin Lontoossa”.  Uusi Suomi. 6.1.2022.  https://www.uusisuomi.fi/uutiset/virologian-professori-maskien-kaytto-on-nyt-tarkeampaa-kuin-koskaan-tilanne-paakaupunkiseudulla-kuin-lontoossa/488a3898-2b85-4b5a-ab09-edb16d5ad59f

Comprehensive Chemosensory Psychophysical Evaluation of Self-reported Gustatory Dysfunction in Patients With Long-term COVID-19. A Cross-sectional Study. JAMA Network. 6.1.2022. https://jamanetwork.com/journals/jamaotolaryngology/fullarticle/2787787?

A National Strategy for the “New Normal” of Life With COVID. JAMA Network. 6.1.2022.  https://jamanetwork.com/journals/jama/article-abstract/2787944

Gut microbiota dynamics in a prospective cohort of patients with post-acute COVID-19 syndrome. BMJ / Gut. 5.1.2022. https://gut.bmj.com/content/early/2022/01/05/gutjnl-2021-325989

South African scientist thinks she may have solved the mystery of long COVID-19, which afflicts 100M people. A recent study by Resia Pretorius and her team at Stellenbosch University in South Africa suggests that long COVID-19 may be triggered by microclots. The Hill. 5.1.2022. https://thehill.com/changing-america/well-being/medical-advances/588443-south-african-scientist-thinks-she-may-have

Association between vaccination status and reported incidence of post-acute COVID-19 symptoms in Israel: a cross-sectional study of patients tested between March 2020 and November 2021. medRxiv. 5.1.2022. https://www.medrxiv.org/content/10.1101/2022.01.05.22268800v2

Practical Indicators for Risk of Airborne Transmission in Shared Indoor Environments and Their Application to COVID-19 Outbreaks. Environmental Science & Technology. 5.1.2022. https://doi.org/10.1021/acs.est.1c06531

Residual SARS-CoV-2 viral antigens detected in GI and hepatic tissues from five recovered patients with COVID-19. @IanRicksecker, A Duke pathology study in Singapore “detected SARS-CoV-2 .. in the colon, appendix, ileum, haemorrhoid, liver, gallbladder and lymph nodes .. suggesting widespread multiorgan involvement of the viral infection.” The same study found “evidence of residual virus in .. tissues during the convalescent phase, up to 6 months after recovery, in a non-postmortem setting,” suggesting that “a negative swab result might not necessarily indicate complete viral clearance from the body.” Gut. 5.1.2022.  gut.bmj/content/gutjnl-2021-324280.full.pdf

Discordant SARS-CoV-2 PCR and Rapid Antigen Test Results. When Infectious: A December 2021 Occupational Case Series. medRxiv. 5.1.2022. Discordant SARS-CoV-2 PCR and Rapid Antigen Test Results When Infectious: A December 2021 Occupational Case Series (medrxiv.org)

By wearing face masks in schools, students protect their learning, families and long-term health. Flawed or unrepresentative studies promote the view that masks are ineffective or harmful. But at times when Covid case rates are high, they’re one of our best options. iNews. 5.1.2022. https://inews.co.uk/opinion/by-wearing-face-masks-in-schools-students-protect-their-learning-families-and-long-term-health-1381627

Practical Indicators for Risk of Airborne Transmission in Shared Indoor Environments and Their Application to COVID-19 Outbreaks. Environ Sci Technol. 5.1.2022. https://pubs.acs.org/doi/10.1021/acs.est.1c06531

Early Israeli findings show fivefold boost from fourth COVID vaccine dose. CIDRAP, University of Minnesota. 4.1.2022. https://www.cidrap.umn.edu/news-perspective/2022/01/early-israeli-findings-show-fivefold-boost-fourth-covid-vaccine-dose

Viikoittaiset tilastot kuolleista julkaistaan jatkossa kerran kuukaudessa. Tilastokeskus. 4.1.2022. https://www.stat.fi/uutinen/viikoittaiset-tilastot-kuolleista-julkaistaan-jatkossa-kerran-kuukaudessa

Long Covid: why do some people have symptoms months after infection? Researchers say more than 100m suffer ill effects for at least 12 weeks. Financial Times. 4.1.2022. https://www.ft.com/content/ed89cad2-6f82-44f0-b01d-c4490e4a7372?shareType=nongift

A framework for reconstructing SARS-CoV-2 transmission dynamics using excess mortality data. (Iran) medRxiv. 4.1.2022. https://www.medrxiv.org/content/10.1101/2021.10.04.21264540v2.full.pdf

Mapping the antigenic diversification of SARS-CoV-2. medRxiv. 3.1.2022. https://www.medrxiv.org/content/10.1101/2022.01.03.21268582v1

Covid-19: An urgent call for global “vaccines-plus” action. BMJ. 3.1.2022. https://www.bmj.com/content/376/bmj.o1

Superspreading: Insufficient ventilation led to a probable long-range airborne transmission of SARS-CoV-2 on two buses. Buiding and Environment. NN.1.2022. https://www.sciencedirect.com/science/article/pii/S0360132321008118?via%3Dihub

The hyper-transmissible SARS-CoV-2 Omicron variant exhibits significant antigenic change, vaccine escape and a switch in cell entry mechanism.  @IanRicksecker, Luckily, the University of Glasgow found that “Whilst Delta is optimised for fusion at the cell surface, Omicron .. achieves entry through endosomal fusion. This switch .. offers [an] explanation for [its] reduced syncytia formation.”1.1.2022. https://t.co/lsAwufl6dl

What is an N95 respirator? N95DECON Publications. 2022. https://www.n95decon.org/publications

2022 January 1 – 10

Are People Optimistically Biased about the Risk of COVID-19 Infection? Lessons from the First Wave of the Pandemic in Europe. Int J Environ Res Public Health. 31.12.2021. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744599/

Studies suggest why omicron is less severe: It spares the lungs. The Seattle Times. 31.12.2021. https://www.seattletimes.com/nation-world/studies-suggest-why-omicron-is-less-severe-it-spares-the-lungs/

Travelers infected one another across hallway in Covid-19 quarantine facility, New Zealand research shows. CNN Travel. 31.12.2021. https://edition.cnn.com/2021/12/30/health/new-zealand-covid-facility-transmission/index.html

Paradoxical sex-specific patterns of autoantibody response to SARS-CoV-2 infection. @IanRicksecker, Those warnings have since been proven by discovery of autoimmune features. This study of 177 Los Angeles healthcare workers found that all had persistent self-attacking antibodies at least 6 months after infection, regardless of illness severity. J Translational Medicine. 30.12.2021. https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-021-03184-8

Covid-19: Is it safe to reduce the self-isolation period? BMJ. 30.12.2021. https://www.bmj.com/content/375/bmj.n3164?

Taiwan rejects US CDC guidance on 5-day quarantine. Some Omicron cases still infectious up to 12 days after testing positive. Taiwan News. 30.12.2021. https://www.taiwannews.com.tw/en/news/4393548

Rekord bei Corona-Neuinfektionen. Die Pandemie erreicht in der Schweiz und weltweit einen neuen Höhepunkt. Mehr als 17’600 Ansteckungen innert 24 Stunden – und das dürfte erst der Anfang einer riesigen Welle in der Schweiz sein. Welche Länder ebenfalls stark betroffen sind. BaZ. 29.12.2021. https://www.bazonline.ch/die-pandemie-erreicht-in-der-schweiz-und-weltweit-einen-neuen-hoehepunkt-318445720632?

The SARS-CoV-2 B.1.1.529 Omicron virus causes attenuated infection and disease in mice and hamsters. Research Square. 29.12.2021. https://www.researchsquare.com/article/rs-1211792/v1

Omikron voi todella olla lievempi – Tutkija: Ihan huippua. Akatemiatutkijan mukaan uusi virusmuunnos ei ilmeisesti pääse leviämään yhtä tuhoisasti keuhkoissa kuin aiempi delta. Verkkouutiset. 29.12.2021. https://www.verkkouutiset.fi/omikron-voi-todella-olla-lievempi-tutkija-ihan-huippua/#773fc543

HUSin ylilääkäri ehdottaa erillisten koronasairaaloiden perustamista Suomeen. Ylilääkäri Eero Hirvensalon mukaan sairaalat olisi mahdollista perustaa terveydenhuollon niukoista resursseista huolimatta, jos mukana olisi useita toimijoita ja soveltuvilta osin yksityinen terveydenhuolto. YLE Uutiset. 29.12.2021. https://yle.fi/uutiset/3-12248864?

Can COVID-19 alter your personality? Here’s what brain research shows. Alzheimer’s, Parkinson’s, and traumatic brain injury can cause changes in behavior by altering brain anatomy. Now it seems the coronavirus can too. National Geographic. 29.12.2021. https://www.nationalgeographic.com/science/article/can-covid-19-alter-your-personality-heres-what-brain-research-shows?cmpid=org=ngp::mc=social::src=twitter::cmp=editorial::add=tw20211229science-sciencecovidpersonalitydisorder&linkId=146317189

CDC shortens recommended Covid-19 isolation and quarantine time. CNN Health. 28.12.2021. https://edition.cnn.com/2021/12/27/health/cdc-covid-quarantine-isolation-shortened-recommendation/index.html?

Intranasal inhibitor blocks omicron and other variants of SARS-CoV-2. Research Square. 28.12.2021. https://www.researchsquare.com/article/rs-1196079/v1

Combined triple treatment of fibrin amyloid microclots and platelet pathology in individuals with Long COVID/ Post-Acute Sequelae of COVID-19 (PASC) can resolve their persistent symptoms. @IanRicksecker, [COVID-19] also causes microclots: “Fibrin(ogen) amyloid microclots and platelet hyperactivation [were] observed in [Long COVID] patients,” in this work by Stellenbosch University of South Africa, which also explored potential treatments. Research Square.  28.12.2021. https://www.researchsquare.com/article/rs-1205453/v1

Risk of Cardiovascular Events after Covid-19: a double-cohort study. (@IanRicksecker) Oregon Health & Science University found that “symptomatic or asymptomatic SARS-CoV-2 infection is associated with increased risk of [fatal] cardiovascular outcomes and has causal effect on all-cause mortality.” medRxiv. 27.12.2021. https://doi.org/10.1101/2021.12.27.21268448

Omicron infection enhances neutralizing immunity against the Delta variant. medRxiv. 27.12.2021.  https://www.medrxiv.org/content/10.1101/2021.12.27.21268439v1.full

Emeritusprofessori: Visiiri suojaa koronalta kuin aurinkolasit HIV:lta. Verkkouutiset. 27.12.2021. https://www.verkkouutiset.fi/emeritusprofessori-visiiri-suojaa-koronalta-yhta-hyvin-kuin-aurinkolasit-hivlta/#773fc543

Characterizing Long COVID in an International Cohort: 7 Months of Symptoms and Their Impact. medRxiv. 27.12.2021. https://www.medrxiv.org/content/10.1101/2020.12.24.20248802v2

Coronavirus Can Persist for Months After Traversing Body. BloombergQuint. 26.12.2021. https://www.bloombergquint.com/coronavirus-outbreak/coronavirus-can-persist-for-months-after-traversing-entire-body.

The omicron (B.1.1.529) SARS-CoV-2 variant of concern does not readily infect Syrian hamsters. bioRxiv. 26.12.2021.  https://www.biorxiv.org/content/10.1101/2021.12.24.474086v1

Aerosol generation during general anesthesia is comparable to coughing: An observational clinical study. Acta Anesthesiologica Scandinavica. 24.12.2021.  https://onlinelibrary.wiley.com/doi/10.1111/aas.1402

SARS-CoV-2 variants of concern and variants under investigation in England. Technical briefing 33. UK Health Security Agency. 23.12.2021. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1043807/technical-briefing-33.pdf

Covid-19: Early studies give hope omicron is milder than other variants. BMJ. 23.12.2021. https://www.bmj.com/content/375/bmj.n3144?

Helsinki GSE:n Tilannehuoneen selvitys: Rokotukset suojaavat lapsia tehokkaasti tartunnoilta – 11-vuotiailla jopa kaksinkertainen määrä tartuntoja 12-vuotiaisiin verrattuna.  Helsinki Graduate School of Economics. 23.12.2021. https://www.helsinkigse.fi/corona/helsinki-gsen-tilannehuoneen-selvitys-rokotukset-suojaavat-lapsia-tehokkaasti-tartunnoilta-11-vuotiailla-jopa-kaksinkertainen-maara-tartuntoja-12-vuotiaisiin-verrattuna/

Coronavirus disease (COVID-19): How is it transmitted? How does COVID-19 spread between people? WHO. 23.12.2021. https://www.who.int/news-room/questions-and-answers/item/coronavirus-disease-covid-19-how-is-it-transmitted

Medical technologies have been central to US pandemic response – but social behaviors matter just as much. The Conversation. 22.12.2021. https://theconversation.com/medical-technologies-have-been-central-to-us-pandemic-response-but-social-behaviors-matter-just-as-much-171587?

Kannattaako oireettoman tehdä koti­testi? Pitääkö lapset testata ennen iso­vanhempien tapaamista? 10 kysymystä ja vastausta toisesta koronajoulusta. Turun yliopiston virusopin professori Ilkka Julkusen mukaan kotitestejä voi hyvin käyttää lieväoireisessa taudissa. Kotitestistä saatuun negatiiviseen tulokseen pitää kuitenkin suhtautua pienellä varauksella. Helsingin Sanomat. 22.12.2021. https://www.hs.fi/hyvinvointi/art-2000008492207.html

11 Early Signs of Dementia. healthline. 22.12.2021. https://www.healthline.com/health/dementia/early-warning-signs

How The Koch Network Hijacked The War On Covid [GBD, Trump]. CMD. 22.12.2021. https://www.exposedbycmd.org/2021/12/22/how-the-koch-network-hijacked-the-war-on-covid/

What now for Sweden and covid-19? BMJ. 22.12.2021. https://www.bmj.com/content/375/bmj.n3081?

Covid News: What the U.S. Vaccination Campaign Looks Like One Year On. Pfizer said a combination of pills reduced the risk of hospitalization and death by 89 percent if given within three days of the onset of symptoms. New York Times. 21.12.2021. https://www.nytimes.com/live/2021/12/14/world/covid-omicron-vaccines#pfizer-covid-pill-paxlovid

In world first, Israel set to give 4th COVID shot to over 60s, at-risk groups. Hailing recommendation by panel of health experts, Bennett orders swift roll-out of extra vaccine booster for people over 60, immunocompromised and health care workers. The Times of Israel. 21.12.2021. https://www.timesofisrael.com/health-ministry-panel-recommends-fourth-covid-shot-for-at-risk-groups/?

Viranomainen määräsi yleisötilaisuudet säppiin – Kirkko vetää omaa linjaa: joulukirkot järjestetään. ”Älytön päätös tässä vaiheessa.” Salon seurakunnassa kritisoidaan tuomiokapitulin ohjetta. Kirkon mukaan uskonnon harjoittaminen auttaa ihmisiä jaksamaan pandemiassa. Suomen Kuvalehti. 21.12.2021. https://suomenkuvalehti.fi/jutut/kotimaa/viranomainen-maarasi-yleisotilaisuudet-sappiin-kirkko-vetaa-omaa-linjaa-joulukirkot-jarjestetaan/?

Koronarajoitukset kiristymässä. Useat alueet ovat tiedottaneet rajoitussuosituksista. Lääkärilehti. 21.12.2021. https://www.laakarilehti.fi/ajassa/ajankohtaista/koronarajoitukset-kiristymassa/?public

December 21 – 31 

SARS-CoV-2 infection and persistence throughout the human body and brain. Research Square. 20.12.2021. https://doi.org/10.21203/rs.3.rs-1139035/v1

Avoin kirje päättäjille: Omikronin torjunta vaatii kiireellisiä rajoitustoimia. Eroonkoronasta. 20.12.2021. https://www.eroonkoronasta.fi/avoin-kirje-paeaettaejille-omikronin-torjunta-vaatii-kiireellisiae-rajoitustoimia/#s_allekirjoittajat

SARS-CoV-2 infection and persistence throughout the human body and brain. Research Square. 20.12.2021. https://assets.researchsquare.com/files/rs-1139035/v1_covered.pdf?c=1640020576

Teholla 63 koronapotilasta – tehohoidon koordinaattorit: Hallituksen tehtävä rajuja päätöksiä ja heti. Professori Matti Reinikainen arvioi, että Suomeen vasta tuloaan tekevä omikron työllistää sairaaloita arvioitua enemmän. Etelä-Afrikassa virus on jyllännyt nuorten keskuudessa. YLE-Uutiset. 20.12.2021. https://yle.fi/uutiset/3-12239558?

Multisystem Inflammatory Syndrome in Children by COVID-19 Vaccination Status of Adolescents in France. JAMA Network. 20.12.2021. https://jamanetwork.com/journals/jama/fullarticle/2787495

Multifactorial seroprofiling dissects the contribution of pre-existing human coronaviruses responses to SARS-CoV-2 immunity. nature. 18.12.2021. https://www.nature.com/articles/s41467-021-27040-x

Ministeri Krista Kiuru: Hätä­jarrusta on päätettävä jo ensi viikolla ja rajoitus­toimia on lisättävä merkittävästi. Kiuru toivoo, että Italian tapaan Suomi alkaa vaatia myös eurooppalaisilta ennen maahan tuloa otettua koronatestitodistusta. Helsingin Sanomat. 18.12.2021. https://www.hs.fi/politiikka/art-2000008474448.html

Status på omikron-varianten (B.1.1.529) pr. Statens Serum Institut finder et stadigt stigende antal omikron tilfælde i Danmark. Samlet er der nu fundet 11.559 tilfælde af smitte med virus-varianten omikron. Alle fakta om forekomsten af omikron i Danmark udsendes nu i en daglig rapport. Statens SerumInstitut. 17.12.2021. https://www.ssi.dk/aktuelt/nyheder/2021/status-pa-omikron-varianten-b11529-pr-171221

Omicron largely evades immunity from past infection or two vaccine doses. Imperial College. 17.12.2021. https://www.imperial.ac.uk/news/232698/omicron-largely-evades-immunity-from-past/

How Omicron Evades Natural Immunity, Vaccination, And Monoclonal Antibody Treatments. Forbes. 17.12.2021. https://www.forbes.com/sites/williamhaseltine/2021/12/17/how-omicron-evades-natural-immunity-vaccination-and-monoclonal-antibody-treatments/?sh=d4e595f60e08

CDC recommends Pfizer, Moderna vaccines over J&J’s. CNN Health. 17.12.2021. https://edition.cnn.com/2021/12/16/health/johnson-vaccine-acip-recommendation-mrna-preferred/index.html

Vaccine inequality may undermine the booster programme. BMJ. 17.12.2021. https://www.bmj.com/content/375/bmj.n3118

Huonossa sisäilmassa koronatartunnan voi saada minuuteissa – tehokas tuuletus laskee riskiä luultua enemmän, kertoo VTT:n tuore tutkimus. Mitä enemmän huonetilassa on viruksia, sitä suurempi on riski taudin leviämisestä. Tuulettamalla viruspitoisuudet tippuvat tutkijoiden mukaan jopa 90 prosenttia. YLE-Uutiset. 16.12.2021. https://yle.fi/uutiset/3-12231997?

Report 48 – The value of vaccine booster doses to mitigate the global impact of the Omicron SARS-CoV-2 variant. Imperial College. 16.12.2021. https://www.imperial.ac.uk/mrc-global-infectious-disease-analysis/covid-19/report-48-global-omicron/

The S1 protein of SARS-CoV-2 crosses the blood-brain barrier in mice. @IanRicksecker The virus appears to be able to cross the blood-brain barrier and cause significant neurological damage. The ability of the spike protein to cross the blood-brain barrier was demonstrated in mice at the University of Washington. Nature Neuroscience. 16.12.2021.  https://doi:10.1038/s41593-020-00771-8.

Report 49 – Growth, population distribution and immune escape of Omicron in England. Imperial College. 16.12.2021. https://www.imperial.ac.uk/mrc-global-infectious-disease-analysis/covid-19/report-49-Omicron/

Missed shots: Science revisits its 2020 Breakthrough of the Year. The COVID-19 vaccine rollout was a spectacular success—and a stunning tragedy. Science . 16.12.2021. https://www.science.org/content/article/missed-shots-science-revisits-its-2020-breakthrough-year?

A tantalizing clue to why omicron is spreading so quickly. NPR. 15.12.2021. https://www.npr.org/sections/goatsandsoda/2021/12/15/1064597592/a-tantalizing-clue-to-why-omicron-is-spreading-so-quickly

HKUMed finds Omicron SARS-CoV-2 can infect faster and better than Delta in human bronchus but with less severe infection in lung. HKU Faculty of Medicine News. 15.12.2021. https://www.med.hku.hk/en/news/press/20211215-omicron-sars-cov-2-infection

Covid-19: Long covid symptoms among hospital inpatients show little improvement after a year, data suggest. BMJ. 15.12.2021. https://www.bmj.com/content/375/bmj.n3092?=&utm_source=adestra&utm_medium=email&utm_campaign=usage&utm_content=daily&utm_term=text

U.S. study suggests vaccines may be ineffective against Omicron without booster. Reuters. 15.12.2021. https://www.reuters.com/business/healthcare-pharmaceuticals/us-study-suggests-covid-19-vaccines-may-be-ineffective-against-omicron-without-2021-12-14/?

Assessment of the further emergence of the SARS-CoV-2 Omicron VOC in the context of the ongoing Delta VOC transmission in the EU/EEA, 18th update. ECDC. 15.12.2021. https://www.ecdc.europa.eu/en/publications-data/covid-19-assessment-further-emergence-omicron-18th-risk-assessment

Pohjois-Pohjanmaalla tahallista koronalle altistumista: ”Liittyy luultavasti koronapassiin”. Kallion kuntayhtymä kertoo huolestuttavasta koronailmiöstä. Iltalehti. 15.12.2021. https://www.iltalehti.fi/koronavirus/a/8ec31170-683e-470c-a3db-091fbc205f23?

THL haluaa rajoille kireämmän linjan kuin hallitus suunnittelee – Ruotsikin on omikronin riskimaa. Valtioneuvosto on päättämässä huomenna torstaina matkustusrajoitusten kiristämisestä. Sisäministeri Mikkonen sanoo, että hallituksessa on keskusteltu myös sisärajatarkastusten palauttamisesta. YLE-Uutiset. 15.12.2021. https://yle.fi/uutiset/3-12231096

REVIEW: How Common is Long COVID in Children and Adolescents? Pediat Incfext Dis J. NN.12.2021. https://journals.lww.com/pidj/fulltext/2021/12000/how_common_is_long_covid_in_children_and.20.aspx

Evidence for a mouse origin of the SARS-CoV-2 Omicron variant. Journal of Genetics and Genomics. nn.12.2021. https://www.sciencedirect.com/science/article/pii/S1673852721003738

Final data on pills to treat Covid-19 holds strong against hospitalization and death, Pfizer says. CNN Health. 14.12.2021. https://edition.cnn.com/2021/12/14/health/pfizer-paxlovid-pills-covid-treatment/index.html?

Pfizer’s Covid Pill Works Well, Company Confirms in Final Analysis. The treatment, called Paxlovid, is likely to work against Omicron and could be available in the United States before the end of the year. New York Times. 14.12.2021.  https://www.nytimes.com/2021/12/14/health/pfizer-covid-19-pill-paxlovid.html?

Sairaalapomot eivät näe hätäjarrulle tarvetta hoidon kuormituksen takia – johtajalääkäri: ”vaikuttavin toimi olisi puuttuminen ravintoloiden aukioloihin”
Koronan omikronmuunnoksen tulevaa vaikutusta sairaaloiden kuormitukseen ei vielä tiedetä. Sosiaali- ja terveysministeriö valmistautuu rajoitusten tiukentamiseen, mutta kahden sairaanhoitopiirin johtajat arvioivat, että toistaiseksi hätäjarrun käytölle ei ole tarvetta. YLE-Uutiset. 14.12.2021. https://yle.fi/uutiset/3-12229385

Pääministeri Marin: Kolmansien rokotusten antamista vauhditettava – ”Työterveyden­huoltoa voitaisiin hyödyntää laajemmin”. Hallitus käsittelee koronatilannetta neuvottelussaan ensi viikon tiistaina 21. joulukuuta. Ilta=sanomat. 14.12.2021. https://www.is.fi/politiikka/art-2000008474610.html

Ministeri Kiuru: Maahantulorajoitukset kiristyvät – kolmansiin rokotuksiin on pyydetty apua puolustusvoimilta
Tänään kokoontunut sote-ministeriryhmä on tehnyt hallitukselle esityksen rajatoimien kiristämisestä sekä lisäavusta kunnille rokotusten järjestämistä varten. YLE-Uutiset. 14.12.2021. https://yle.fi/uutiset/3-12230314

Hollanti sulkee koulut etuajassa koronan takia. Hollannissa koululaiset pääsevät joululomalle viikkoa aiemmin heikentyneen koronatilanteen takia.Iltalehti. 14.12.2021. https://www.iltalehti.fi/ulkomaat/a/e41dd356-07b6-4a15-810a-93921e9794bb

Covid-19: Almost 100 ICU staff from Malaga hospital test positive after Christmas lunch. BMJ. 14.12.2021. https://www.bmj.com/content/375/bmj.n3085?

Why do Covid boosters offer greater protection against Omicron? Studies show three jabs are more effective than two as manufacturers work on variant-specific vaccines. Financial Times. 14.12.2021. https://www.ft.com/content/8a6a0ec8-fd07-49cd-a3f5-386a06269a5c

Merck’s COVID pill loses its lustre: what that means for the pandemic. Molnupiravir was initially heralded by public-health officials as a game-changer for COVID-19, but full clinical-trial data showed lower-than-expected efficacy. Nature. 13.12.2021. https://www.nature.com/articles/d41586-021-03667-0?

Meet the Vaccine Scientists: TIME’s Heroes of the Year. TIME. 13.12.2021. https://view.newsletters.time.com/?

Where I Live, No One Cares About COVID. Outside the world inhabited by the professional classes in a handful of major metropolitan areas, many Americans are leading their lives as if COVID is over. Atlantic. 13.12.2021. https://www.theatlantic.com/ideas/archive/2021/12/where-i-live-no-one-cares-about-covid/620958/

COVID-19-tutkimuskatsaus 13/2021. Valtioneuvosto. 13.12.2021. https://julkaisut.valtioneuvosto.fi/handle/10024/163688

Risikovurdering af omikron. Statens Seruminstitut. 12.12.2021. https://covid19.ssi.dk/-/media/arkiv/subsites/covid19/risikovurderinger/risikovurdering_omikron_121221_ssi.pdf?la=da

HUS: Neljä kymmenestä teho-osastolla hoidetuista koronapotilaista ei ollut palannut työhön tai harrastukseen kolme kuukautta kotiutumisen jälkeen. Teho-osastolle joutuneiden koronapotilaiden keski-ikä on koko epidemian ajalta 57 vuotta. Nuorempien ikäryhmien osuus tehohoidossa olevista koronapotilaista on kasvanut. YLE Uutiset. 11.12.2021. https://yle.fi/uutiset/3-12225995

Modelling the potential consequences of the Omicron. SARS-CoV-2 variant in England. 11.12.2021. https://cmmid.github.io/topics/covid19/reports/omicron_england/report_11_dec_2021.pdf

 

December 11 – 20 

South Africa: early data suggest Omicron is more transmissible but less severe. The Conversation. 10.12.2021. https://theconversation.com/south-africa-early-data-suggest-omicron-is-more-transmissible-but-less-severe-173517?

Uusi tutkimus: tässä ajassa kaksi koronarokotetta ottaneiden suoja tartuntaa vastaan heikkenee. Koronarokotteiden teho hiipuu kolmen kuukauden jälkeen. Ilta=sanomat. 10.12.2021. https://www.is.fi/terveys/art-2000008464942.html?

Lopettaako Suomi rokotteiden tilaamisen? Hallitukselta vaaditaan vastauksia. Kokoomuksen Terhi Koulumies kysyy, aikooko Suomi todellakin peruuttaa rokotetilauksiaan. Verkkouutiset. 10.12.2021. https://www.verkkouutiset.fi/lopettaako-suomi-rokotteiden-tilaamisen-hallitukselta-vaaditaan-vastauksia/#773fc543

Filtration Efficiency of Face Masks Used by the Public During the COVID-19 Pandemic. JAMA Internal Medicine. 10.12.2021. https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2774265

The Hunt for a Single Shot to Defeat Omicron and All Coronaviruses. While the science is still in its early stages, the hardest part about developing a super-vaccine for all coronaviruses could be finding a way to pay for it. Bloomberg. 9.12.2021. https://www.bloomberg.com/news/features/2021-12-09/could-a-one-shot-coronavirus-vaccine-protect-you-from-all-variants

Alarm as almost 20% of South Africa’s healthcare workers contract Covid. Mail&Guardian. 9.12.2021. https://mg.co.za/coronavirus-essentials/2021-12-09-alarm-as-almost-20-of-south-africas-healthcare-workers-contract-covid/

16- and 17-year-olds are now eligible for a Pfizer/BioNTech Covid-19 vaccine booster. CNN Health. 9.12.2021. https://edition.cnn.com/2021/12/09/health/covid-booster-adolescents-fda-authorization/index.html?

STM huolestui Suomen kouluista ja lasten tartuntojen noususta – vetoomus THL:lle. WHO kehotti koronatoimiin peruskouluissa. STM huolestui Suomen tilanteesta ja vetoaa nyt THL:ään. Uusi Suomi. 9.12.2021. https://www.uusisuomi.fi/uutiset/stm-huolestui-suomen-kouluista-ja-lasten-tartuntojen-noususta-vetoomus-thllle/c1dd0e38-6941-44ca-a929-381ca8b4f7ea

Corona infections and air quality. More infections in poorly ventilated classrooms. Indoor air quality has an influence on how many corona virus infections occur there. This has now been shown for the first time in a pilot project involving Empa researchers in 150 primary school classrooms in Graubünden. The analysis also showed that the air quality in many classrooms is poor. The study concluded that regular ventilation of classrooms is therefore very important, even in winter months. EMPA. 9.12.2021. https://www.empa.ch/web/s604/covid-and-co2

Study shows benefit of regular classroom ventilation classroom. A Swiss study has found that poorly ventilated school classrooms record up to six times as many Covid-19 cases compared with those which are regularly aired. SwissInfo. 9.12.2021. https://www.swissinfo.ch/eng/society/study-shows-benefit-of-regular-classroom-ventilation/47179498

Ensimmäiset merkit omikronin kyvystä väistää rokotussuoja ilmi – Melatoniinista ja D-vitamiinista nyt apu pandemian hallintaan? (Mikko Paunio). Uusi Suomi. 8.12.2021. https://puheenvuoro.uusisuomi.fi/mikkopaunio/ensimmaiset-merkit-omikronin-kyvysta-vaistaa-rokotussuoja-ilmi-melatoniinista-ja-d-vitamiinista-nyt-apu-pandemian-hallintaan/

Pfizer antoi ensimmäisen arvion koronarokotteensa tehosta omikronmuunnosta vastaan. Kolmas annos Comirnaty-rokotetta herättää alustavien tulosten mukaan lupaavan paljon vasta-aineita omikronvarianttia vastaan. Mediuutiset. 8.12.2021. https://www.mediuutiset.fi/uutiset/mu/a4697e4f-84b6-45c1-8c32-dd112e1b581e?ref=newsletter:66d0&utm

Pfizer, BioNTech vaccine neutralises Omicron with three shots.  Reuters. 8.12.2021. https://www.reuters.com/business/healthcare-pharmaceuticals/biontech-pfizer-say-test-shows-3-doses-vaccine-neutralise-omicron-2021-12-08/

PFIZER AND BIONTECH PROVIDE UPDATE ON OMICRON VARIANT. Pfizer. 8.12.2021. https://www.pfizer.com/news/press-release/press-release-detail/pfizer-and-biontech-provide-update-omicron-variant

Scientists Discover Harder-to-Detect Version of Omicron. Bloomberg. 8.12.2021. https://www.bloomberg.com/news/articles/2021-12-08/australia-finds-new-omicron-lineage-in-arrival-from-south-africa?cmpid=BBD120821_BIZ&utm_medium=email&utm_source=newsletter&utm_term=211208&utm_campaign=bloombergdaily

Tanska sulkee koulut. Aiemmin Tanska kertoi, että omikron leviää koko yhteiskunnassa. Iltalehti. 8.12.2021. https://www.iltalehti.fi/ulkomaat/a/55748a61-25a4-4f07-ade8-c03eb3c64d3d

Tallinnan-laivalta pääsi kävelemään suoraan Helsinkiin, vaikka kuulutus varoitti koronapassin tarkastuksesta. Katajanokan terminaalissa Helsingissä ei tarkastettu koronapasseja matkustajilta vaan jaettiin vanhentunutta ohjetta koronatestiin menemisestä. HS. 8.12.2021. https://www.hs.fi/kaupunki/art-2000008460200.html?share=583b747344b857ca56a08ac8b1522f47

COVID-19 Community Response Framework v4.0. New Zealand Government. 8.12.2021. https://www.health.govt.nz/system/files/documents/pages/covid-19_community_protection_framework_v4.0_8_dec_2021.pdf

Omicron coronavirus variant partly evades Pfizer vaccine’s protection, study shows. CNN Health. 8.12.2021. https://edition.cnn.com/2021/12/07/health/omicron-variant-pfizer-vaccine-south-africa-study/index.html

Omikronin vakavat tapaukset lisääntyvät räjähdysmäisesti. Verkkouutiset. 8.12.2021. https://www.verkkouutiset.fi/omikronin-vakavat-tapaukset-lisaantyvat-rajahdysmaisesti/#7e9b2b60

Reduced Neutralization of SARS-CoV-2 Omicron Variant by Vaccine Sera and monoclonal antibodies. medRxiv. 8.12.2021.  https://www.medrxiv.org/content/10.1101/2021.12.07.21267432v1.full.pdf

Soomest sisse toodud haigusjuhtude arv kasvab. 8.12.2021. https://www.err.ee/1608429296/soomest-sisse-toodud-haigusjuhtude-arv-kasvab

Omikron paljasti leviämisensä saloja: Se on lainannut geneettistä koodia tavalliselta flunssalta.  Koronan sairastaminen näyttää suojaavaan uudelta koronatartunnalta kolme kertaa huonommin, jos tartuttaja on deltamuunnoksen sijasta omikron. Mediuutiset. 8.12.2021. https://www.mediuutiset.fi/uutiset/mu/82024ba4-be86-433f-ad9d-c7783cbb8bad

Frequency of Neurologic Manifestations in COVID-19. A Systematic Review and Meta-analysis. Neurology. 7.12.2022. https://n.neurology.org/content/97/23/e2269

Persistence of clinically relevant levels of SARS-CoV2 envelope gene subgenomic RNAs in non-immunocompromised individuals. International Journal of Infectious Diseases. 7.12.2021. https://www.ijidonline.com/article/S1201-9712(21)01206-6/fulltext

An upper bound on one-to-one exposure to infectious human respiratory particles. PLOS One. 7.12.2021. https://www.pnas.org/content/118/49/e2110117118

Anders Tegnell svarade på läsarnas frågor om corona. Expressen. 7.12.2021. https://www.expressen.se/nyheter/anders-tegnell-svarar-pa-dina-fragor-om-corona-/

Omicron variant of SARS-CoV-2 harbors a unique insertion mutation of putative viral or human genomic origin. OSF Preprints. 7.12.2021. https://osf.io/f7txy/

FHI: Alvorlig situasjon, men lite sannsynlig at omikron gir mer alvorlig sykdom. Det er ingen sikre tegn på at smittesituasjonen er i ferd med å snu. Folkehelseinstituttet (FHI) forventer en betydelig forverring for sykehusene selv om omikron trolig ikke gir mer alvorlig sykdom.NRK 7.12.2021. https://www.nrk.no/norge/fhi_-alvorlig-situasjon_-men-lite-sannsynlig-at-omikron-gir-mer-alvorlig-sykdom-1.15761037

Monet maat antavat jo keppiä rokottamattomille – Tässä lista 11 valtion käyttämistä kovista keinoista. Useat maat iskevät rokottamattomille sanktioita, kertoo uutistoimisto Bloomberg. Kovien keinojen joukossa ovat esimerkiksi lihavat sakot ja lomautukset. Mediuutiset. 7.12.2021. https://www.mediuutiset.fi/uutiset/monet-maat-antavat-jo-keppia-rokottamattomille-tassa-lista-11-valtion-kayttamista-kovista-keinoista/aed61f0a-b5ea-43d5-b1af-d9724675ff2c

Sollen auch Geimpfte und Genesene Maske tragen? Vielerorts gilt wieder Maskenpflicht. Eine neue Studie zeigt: FFP2-Masken schützen weit besser als medizinische Masken. Was Sie dazu wissen sollten. BaZ. 6.12.2021. https://www.bazonline.ch/sollen-auch-geimpfte-und-genesene-maske-tragen-447605008512

Omicron can reset the World’s Covid Strategy. Bloomberg. 5.12.2021. https://www.bloomberg.com/opinion/articles/2021-12-05/omicron-is-unavoidable-but-it-s-not-time-to-give-in-to-covid-panic

Prognosis. Initial Hospital Data in Omicron Epicenter Shows Milder Disease. Most patients in Covid wards have not been oxygen dependent. This seems different from earlier waves where fewer vaccinated. Bloomberg. 5.12.2021.  https://www.bloomberg.com/news/articles/2021-12-05/initial-hospital-data-in-omicron-epicenter-shows-milder-disease?cmpid=BBD120621_MKT&utm_medium=email&utm_source=newsletter&utm_term=211206&utm_campaign=markets

Tshwane District Omicron Variant Patient Profile – Early Features. SAMRC. 4.12.2021. https://www.samrc.ac.za/news/tshwane-district-omicron-variant-patient-profile-early-features

Covid-19: Antibody boost after third dose varies greatly by vaccine, study finds.  BMJ. 3.12.2021. doi: https://doi.org/10.1136/bmj.n3011

NHS forecasts 230,000 extra cases of PTSD in England due to Covid. Post-traumatic stress disorder diagnoses likely be among domestic abuse victims, care workers and the bereaved. Guardian. 3.12.2021.  https://www.theguardian.com/society/2021/dec/03/nhs-forecasts-230000-extra-cases-of-ptsd-in-england-due-to-covid?utm_term=Autofeed&CMP=twt_gu&utm_medium&utm_source=Twitter#Echobox=1638513650

COVID-19: Omicron has ’substantial’ ability to evade immunity from previous coronavirus infection. Researchers at the National Institute for Communicable Diseases (NICD) warn their finding has important public health implications. Sky News. 3.12.2021. https://news.sky.com/story/covid-19-omicron-has-substantial-ability-to-evade-immunity-from-previous-coronavirus-infection-12484840

Disorders of Consciousness Associated With COVID-19
A Prospective Multimodal Study of Recovery and Brain Connectivity. Neurology. 18.12.2021. https://n.neurology.org/content/98/3/e315.long

KORONAVIRUS ON TAPPANUT KAHDEN VUODEN AIKANA JO YLI VIISI MILJOONAA IHMISTÄ. MUTTA MITEN SE SAI ALKUNSA? VASTA NYT SUURI SALAISUUS ALKAA RATKETA. HS Kuukausiliite.12. 3.12.2021. https://www.hs.fi/kuukausiliite/art-2000008369960.html?share=6e9bd8e471f70562f7ded6e3bbcaff37

Koronavirus leviää ilmateitse – onko sillä merkitystä?
On hämmästyttävää, miten vähän on varmaa tietoa siitä, millä lailla yleiset ylähengitysteiden tartuntataudit tarttuvat. Lyhyessä ajassa on käynyt selväksi, että aiemmin tunnettujen kosketus- ja pisaratartuntamekanismien lisäksi aerosolivälitteinen leviäminen on yleistä (1,2). Usein näiden reittien erottaminen ei ole helppoa. Infektoitunut voi tartuttaa vieressä seisovan terveen henkilön kaikilla kolmella tavalla. Kaukana tartunnan saaneesta olevat eivät voi saada tartuntatautia kosketus- tai pisaratartuntana – jäljelle jää siis aerosolitartunta.Lääkärilehti. 3.12.2021. https://www.laakarilehti.fi/ajassa/paakirjoitukset-tiede/koronavirus-leviaa-ilmateitse-ndash-onko-silla-merkitysta/?utm_medium=newsletter&utm_source=uk&utm_campaign=uk48pe-2021&m=NDA3NDYsZjg0YjM5MTczMzZhYWI4MDQ1YWIyMzMxOGU3YTcwNmM%3D

COVID-19 vaccine surveillance report. Week 48. UK Health Security Agency. 3.12.2021. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1037987/Vaccine-surveillance-report-week-48.pdf

Impact of community masking on COVID-19: A cluster-randomized trial in Bangladesh. Science. 2.12.2021. https://www.science.org/doi/10.1126/science.abi9069

Covid: Trigger of rare blood clots with AstraZeneca jab found by scientists. BBC. 2.12.2021. https://www.bbc.com/news/health-59418123

Prevalence of ongoing symptoms following coronavirus (COVID-19) infection in the UK : 2 December 2021
Estimates of the prevalence of self-reported long COVID and associated activity limitation, using UK Coronavirus (COVID-19) Infection Survey data. ONS. 2.12.2021.  https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/prevalenceofongoingsymptomsfollowingcoronaviruscovid19infectionintheuk/2december2021

THL: Kolmas koronarokote annetaan kaikille täysi-ikäisille – Osa saa Comirnatyn, osa Spikevaxin. ”Koska kaksi koronarokotetta ei täysin estä tartuntoja, kolmansilla annoksilla saadaan edelleen ehkäistyä tartuntojen leviämistä myös nuoremmissa ikäryhmissä.” Mediuutiset. 2.12.2021. https://www.mediuutiset.fi/uutiset/thl-kolmas-koronarokote-annetaan-kaikille-taysi-ikaisille-osa-saa-comirnatyn-osa-spikevaxin/c412884b-f0b8-4060-9cb5-e5c0eadbeecf

Safety and immunogenicity of seven COVID-19 vaccines as a third dose (booster) following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK (COV-BOOST): a blinded, multicentre, randomised, controlled, phase 2 trial. 2.12.2021. Lancet.  https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)02717-3/fulltext

How bad is Omicron? What scientists know so far
COVID researchers are working at breakneck speed to learn about the variant’s transmissibility, severity and ability to evade vaccines. Nature 2.12.2021.  https://www.nature.com/articles/d41586-021-03614-z?fbclid=IwAR3j_uqwpXhvx6W2afVU10mL0yqbhL6SxymfsWqooYj9FLdQpVKHpu8GUJY

THL suosittelee, että kolmansia koronarokoteannoksia aletaan tarjota kaikille 18 vuotta täyttäneille 5–6 kuukautta toisesta annoksesta. THL. 2.12.2021. https://thl.fi/-/thl-suosittelee-etta-kolmansia-koronarokoteannoksia-aletaan-tarjota-kaikille-18-vuotta-tayttaneille-5-6-kuukautta-toisesta-annoksesta

Aikuisista yli 99 % täysrokotettuja, mutta korona ryöpsähti silti – Gibraltarin tapaus ihmetyttää, mutta nyt ”tehosterokote todella toimii”. Pienen Gibraltarin koronatilanne nousee tällä hetkellä toistuvasti esiin rokotekeskusteluissa, koska maa on täysin rokotettu mutta tartunnat lähtivät silti eksponentiaaliseen kasvuun. Mediuutiset. 2.12.2021. https://www.mediuutiset.fi/uutiset/mu/b186ff7e-3f3e-421e-831e-e443b38ea80c?ref=newsletter:6bbc&utm_source=uutiskirje%40mediuutiset.fi&utm_medium=email&utm_campaign=MU-Uutiskirje-laakari

Omicron will likely ‘dominate and overwhelm’ the world in 3-6 months, doctor says. “Frankly, omicron will dominate and overwhelm the whole world in three to six months,” Singapore doctor Leong Hoe Nam told CNBC’s “Street Signs Asia.”
New vaccines targeting omicron are a “nice idea” but won’t be practical because of the transmissibility of the strain, he said.
Experts don’t know exactly how contagious the highly mutated omicron variant is, but the virus’ spike protein — which binds to human cells — has mutations associated with higher transmission and a decrease in antibody protection. CNBC. 2.12.2021. https://www.cnbc.com/2021/12/02/omicron-to-dominate-and-overwhelm-the-world-in-3-6-months-doctor-says.html

Sotrovimab: New COVID drug which cuts risk of hospitalisation and death by 79% approved for use in UK in people aged 12 years and older. Xevundy, also known as sotrovimab, has been approved for anyone aged 12 and over, who weighs more than 40kg. It is authorised for use in people who have a mild or moderate COVID infection and who are at risk of developing severe illness, Sky News. 2.12.2021. https://news.sky.com/story/sotrovimab-new-covid-drug-which-cuts-risk-of-hospitalisation-and-death-by-79-approved-for-use-in-uk-in-people-aged-12-years-and-older-12484329

Vanhojen näytteiden analyysi paljasti: omikron kiersi jo lokakuussa – kolme teoriaa muunnoksen synnystä. Omikron ei ole kehittynyt deltamuunnoksesta. Iltalehti. 1.12.2021. https://www.iltalehti.fi/ulkomaat/a/a02107be-f1ba-4201-b21f-68ed088ea524?utm_source=iltalehti.fi&utm_medium=email&utm_campaign=email_il_uutiskirje

Visualising SARS-CoV-2 transmission routes and mitigations. BMJ. 1.12.2021. https://www.bmj.com/content/375/bmj-2021-065312

Expert elicitation on the relative importance of possible SARS-CoV-2 transmission routes and the effectiveness of mitigations. BMJ. 1.12.2021. https://bmjopen.bmj.com/content/11/12/e050869

The Coronavirus in a Tiny Drop. NYT. 1.12.2021.  https://www.nytimes.com/interactive/2021/12/01/science/coronavirus-aerosol-simulation.html

ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome. Science. 1.12.2021. https://www.science.org/doi/10.1126/sciadv.abl8213

COVID-19 Post-acute Sequelae Among Adults: 12 Month Mortality Risk. Frontiers in Medicine. 1.12.2021. https://www.frontiersin.org/articles/10.3389/fmed.2021.778434/full

Airborne infection with Covid-19? A historical look at a current controversy. Microbes and Infection. Nov-Dec. 2021. https://www.sciencedirect.com/science/article/pii/S1286457921000733

1 – 10. Joulukuuta

Misinformation Kills. Learn How to Counter It. University of Toronto. 30.11.2021. https://temertymedicine.utoronto.ca/event/misinformation-kills-learn-how-counter-it

Health Department-Reported Cases of Multisystem Inflammatory Syndrome in Children (MIS-C) in the United States. @IanRicksecker You may think, at least our children are safe. They are not. The CDC is tracking incidence of a life-threatening multisystem inflammatory syndrome in children following an acute COVID-19 infection, with 5,973 cases as of November 30, 2021. CDC Covid Data Tracker.  updated 30.11.2021. https://covid.cdc.gov/covid-data-tracker/#mis-national-surveillance

Ilmanvaihto-ohjeistus varhaiskasvatuksen, opetuksen ja koulutuksen tilojen käytöstä vastaaville. THL. 30.11.2021. https://thl.fi/fi/web/ymparistoterveys/sisailma/koronavirus-ja-sisailman-turvallisuus/ilmanvaihto-ohjeistus-varhaiskasvatuksen-opetuksen-ja-koulutuksen-tilojen-kaytosta-vastaaville

Omicron variant found in two previous test samples. RIVM has found the Omicron variant in test samples taken in the Netherlands earlier in November. These samples were taken in the GGD test lanes on 19 and 23 November 2021. Saltro, the lab that analysed the tests, submitted the samples when requested by RIVM. RIVM. 30.11.2021. https://www.rivm.nl/en/news/omicron-variant-found-in-two-previous-test-samples?utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=newsAlerts&utm_term=coronavirus&utm_content=2021-12-01&apid=35182891&rvid=36e7b8c23c4809c80789f33a578dd1ee1d782a7186ca0f4d83fca8b14a1a75e7

COVID-19: Why the Omicron variant has scientists worried.
Scientists have detected cases of a new variant of SARS-CoV-2, which is the virus that causes COVID-19, in a number of countries. Omicron (B.1.1.529) has an unprecedentedly large number of mutations in the part of its genome that encodes a key section of its spike protein, which the virus uses to infect host cells. This suggests that Omicron may be able to evade some of the immune protection afforded by vaccines, many of which are based on the original spike protein, and past infections. Medical News Today. 29.11.2021. https://www.medicalnewstoday.com/articles/covid-19-why-the-omicron-variant-has-scientists-worried?utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=newsAlerts&utm_term=coronavirus&utm_content=2021-11-29&apid=35182891&rvid=36e7b8c23c4809c80789f33a578dd1ee1d782a7186ca0f4d83fca8b14a1a75e7

Why WHO skipped two letters of the Greek alphabet in naming Omicron. CNN Health. 29.11.2021. https://edition.cnn.com/2021/11/29/health/omicron-covid-variant-naming-cec/index.html

WHO Director-General’s opening remarks at the Special Session of the World Health Assembly – 29 November 2021. WHO. 29.11.2021. https://www.who.int/director-general/speeches/detail/who-director-general-s-opening-remarks-at-the-special-session-of-the-world-health-assembly—29-november-2021

Det svenska coronaexperimentet. Den negativa uppmärksamhet som statsepidemiolog Anders Tegnell, eller den svenska strategin över huvud taget, fick möta berodde till övervägande del på dödsfallen inom äldrevården. När många europeiska länder förbereder sig för att återinföra coronarestriktioner är läget i Sverige förhållandevis lugnt: Den svenske journalisten Johan Anderberg beskriver i en uppmärksammad bok hur den omdiskuterade svenska strategin föddes. HBL 29.11.2021. https://www.hbl.fi/artikel/det-svenska-coronaexperimentet/?utm_source=HBL%3As+nyhetsbrev&utm_campaign=25221686e9-veckans_kulturplock&utm_medium=email&utm_term=0_6233309afd-25221686e9-323144264

Professorit vetosivat sunnuntaina kolmannen koronarokotuksen kiirehtimiseksi. Iltalehden mukaan THL ja Kansallinen rokotusasiantuntijaryhmä (Krar) eivät ole noudattaneet hallituksen pyyntöjä nopeuttaa kolmannen koronarokotuskierroksen aloittamista alle 60-vuotiaiden keskuudessa. Mediuutiset. 29.11.2021. https://www.mediuutiset.fi/uutiset/mu/38fd6be0-71d9-48be-ad6d-59a8ed59356b?ref=newsletter:30ac&utm_source=uutiskirje%40mediuutiset.fi&utm_medium=email&utm_campaign=MU-Uutiskirje-laakari

Asiantuntijat vaativat HS:n mielipide­kirjoituksessa kiirehtimään kolmansia rokotuksia – näkevät merkittävän ongelman THL:n Nohynekin arviossa. Lasse Lehtonen, Tuuli Lappalainen, Marjukka Myllärniemi ja Mark Daly kommentoivat THL:n Hanna Nohynekin sanomisia HS:n mielipidekirjoituksessa. Ilta=Sanomat. 29.11.2021. https://www.is.fi/kotimaa/art-2000008438117.html

IL:n tiedot: Kolmatta rokotekierrosta ei ole nopeutettu, vaikka hallitus vaatii. ”Kansallisen rokoteasiantuntijaryhmän (KRAR) sihteeri Hanna Nohynek on ollut laumasuoja-ajattelun vallassa, eikä ole halunnut aloittaa kolmatta rokotuskierrosta”, hallituslähde sanoo Iltalehdelle. Iltalehti. 28.11.2021. https://www.iltalehti.fi/politiikka/a/0541d1ca-f803-4de0-8c0a-5ba10b07820e

Soininvaara. 28.11.2021.

Neljäs aalto on pysäytettävä

DAILY HOSPITAL SURVEILLANCE (DATCOV) REPORT. Dept of Health, Govt of South Africa. 28.11.2021. https://www.nicd.ac.za/wp-content/uploads/2021/11/Datcov-National-Report-20211128.pdf

DAILY HOSPITAL SURVEILLANCE (DATCOV) REPORT

IS:n tiedot: Hallitus kaavailee rajoitus­toimia ”kohtalaisen riskin” tilaisuuksiin – pöydällä valta­kunnallinen etä­työ­suositus. THL:n ympärillä pyörivä keskustelu kiristää tunnelmia hallituksen sisällä. Yksi hallituslähde kritisoi THL:n suhtautumista kolmanteen rokotuskierrokseen. Toinen hallituslähde ihmettelee, miksi ”koronan hoidon ammattilaisten” uskottavuutta halutaan nakertaa. Ilta=Sanomat. 28.11.2021. https://www.is.fi/politiikka/art-2000008438790.html

South African doctor who raised alarm about omicron variant says symptoms are ‘unusual but mild’. Dr Angelique Coetzee noticed otherwise healthy patients showing unusual symptoms and worries how the new variant might hurt the elderly. The Telegraph. 27.11.2021. https://www.telegraph.co.uk/global-health/science-and-disease/south-african-doctor-raised-alarm-omicron-variant-says-symptoms/

A wind speed threshold for increased outdoor transmission of coronavirus: an ecological study. BMC Infectious Diseases. 27.11.2021. https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-021-06796-z

Tutkijat havaitsivat Etelä-Afrikassa huolestuttavan koronamuunnoksen, jota vastaan rokotteet eivät välttämättä suojaa tehokkaasti. Britannia ja Israel keskeyttävät muunnoksen vuoksi kaikki lennot eteläisen Afrikan maista. YLE Uutiset 26.11.-2021. https://yle.fi/uutiset/3-12204926

What We Know So Far About the New Variant of COVID-19 Raising Alarms Globally. TIME Health. 26.11.2021.  https://time.com/6124074/covid-19-new-variant-europe/?utm_medium=email&utm_source=sfmc&utm_campaign=newsletter+coronavirus+default+ac&utm_content=+++20211129+++body&et_rid=95369053&lctg=95369053

Why don’t we just open windows. BMJ. 26.11.2021. doi: https://doi.org/10.1136/bmj.n2895

Koronan pikatestejä myydään nyt enemmän kuin koskaan aiemmin – infektiolääkäri (Irma Koivula, KYS): Oireettomalle pikkujoulujuhlijalle se ei ole vaihtoehto. Koronan pikatestien saatavuudessa on tällä hetkellä jonkin verran ongelmia. Apteekeista ja marketeista saatavat kotitestit ovat luotettavia, mutta oireettomien on turha käyttää niitä. YLE Uutiset. 26.11.2021. https://yle.fi/uutiset/3-12205306

Elapsed time since BNT162b2 vaccine and risk of SARS-CoV-2 infection: test negative design study. BMJ. 25.11.2021. https://doi.org/10.1136/bmj-2021-067873

COVID-19 vaccine weekly surveillance reports (weeks 39 to 47). Data on the real-world effectiveness and impact of the COVID-19 vaccines. Gov.UK. 25.11.2021. https://www.gov.uk/government/publications/covid-19-vaccine-weekly-surveillance-reports

Headlines play down the gravity of covid-19 in children. BMJ. 25.11.2021. https://www.bmj.com/content/375/bmj.n2826

Jos sulkee silmät, törmää seinään. Tuomas Aivelo, TIEDE. 25.11.2021. https://www.tiede.fi/blogit/kaiken-takana-loinen/jos-sulkee-silmat-tormaa-seinaa

Covid Conspiracy theorists: A spotters’ guide. Categorising Covid conspiracy theorists. You can do this at Thanksgiving, but don’t tell your antivax relatives. The Hat Tip. 25.11.2021. https://arieh.substack.com/p/covid-conspiracy-theorists-a-spotters

Scientists warn of new Covid variant with high number of mutations. The B.1.1.529 [Omicron] variant was first spotted in Botswana and six cases have been found in South Africa. Guardian. 24.11.2021. https://www.theguardian.com/world/2021/nov/24/scientists-warn-of-new-covid-variant-with-high-number-of-mutations

Koronarokotusten annosväli taas esillä, kun kolmansien annosten jakelu etenee – asiantuntija: kaikki riippuu siitä, mitä rokotusohjelmalla halutaan saada aikaan
Koronapandemian alkaessa harva tiesi RNA-rokotteista tai siitä, millaisella annosvälillä rokotteet tulisi antaa parhaan mahdollisen suojan varmistamiseksi. Siksi käytännöt ovat vaihdelleet eri puolilla maailmaa. YLE-Uutiset. 24.11.2021. https://yle.fi/uutiset/3-12199445?utm_source=newsletter&utm_medium=email&utm_campaign=newsdaily&utm_content=2021-11-24

Do vaccines protect against long COVID? What the data say. Vaccines reduce the risk of developing COVID-19 — but studies disagree on their protective effect against long COVID. Nature. 23.11.2021. https://www.nature.com/articles/d41586-021-03495-2

Assessment of Sequelae of COVID-19 Nearly 1 Year After Diagnosis. Frontiers in Medicine. 23.11.2021. https://www.frontiersin.org/articles/10.3389/fmed.2021.717194/full

Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy clinical trial.  Science. 23.11.2021. https://www.science.org/doi/10.1126/science.abm3425

Tyksin teho­hoidon yli­lääkärillä on selkeä viesti rokote­keskusteluun: ”Jos yhteis­kunta unohtaa tärkeimmän periaatteensa, ollaan matkalla kohti jotain aivan muuta kuin demokratiaa”
Tyksin tehohoidon ylilääkäri Mika Valtonen on huomannut, että etenkin nuoret lääkärit kokevat toisinaan voimakasta turhautumista hoitaessaan rokottamattomia potilaita. Helsingin Sanomat. 22.11.2021.  https://www.hs.fi/hyvinvointi/art-2000008400399.html

COVID in Israel: Booster Shot Much More Effective Than First Two Shots, Officials Believe
Meanwhile, Israel’s pandemic advisory panel recommended a COVID booster shot to be administered to teens. Haaretz. 22.11.2021. https://www.haaretz.com/israel-news/covid-in-israel-booster-shot-much-more-effective-than-first-two-shots-1.10404207

Kuusamon ja Suomen koronatilanne ja käytännön ratkaisuvaihtoehdot. Koronatilanteesta keskustelemassa muun muassa ympäristöterveyden tutkimusprofessori emeritus Matti Jantunen, keuhkosairauksien professori Marjukka Myllärniemi, empiirisen makrotaloustieteen professori Antti Ripatti ja taloustieteen ja terveystaloustieteen tutkijatohtori Liisa T. Laine. 22.11.2021. https://docs.google.com/presentation/d/1Za6SpkoJvdwF_A3VaXSeIwlf82IlGRq2pFweB-69a78/edit#slide=id.g1026011fdb7_1_18

Israel testasi varautumista koronaviruksen ”tuomiopäivän-varianttiin” – nämä heikkoudet Omega-harjoitus paljasti. MTV Uutiset. 21.11.2021. https://www.mtvuutiset.fi/artikkeli/israel-testasi-varautumista-koronaviruksen-tuomiopaivan-varianttiin-nama-heikkoudet-omega-harjoitus-paljasti/8294924?fbclid=IwAR1uE8gsKjB55uLTiQLpEvECTVWhMjHzsgqpKHVKbbl4wmmgFIHqPtgGayY#gs.he4msi.

November 21 – 30

Persistent symptoms following SARS-CoV-2 infection amongst children and young people: A meta-analysis of controlled and uncontrolled studies. Journal of Infection. 19.11.2021. https://www.journalofinfection.com/article/S0163-4453(21)00555-7/fulltext#%20

CDC recommends Covid-19 boosters for all adults. CNN Health. 19.11.2021. https://edition.cnn.com/2021/11/19/health/covid-vaccine-boosters-fda-cdc/index.html?

The epidemiological relevance of the COVID-19-vaccinated population is increasing, Lancet. 19.11.2021. https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(21)00258-1/fulltext

Effectiveness of public health measures in reducing the incidence of covid-19, SARS-CoV-2 transmission, and covid-19 mortality: systematic review and meta-analysis. BMJ. 18.11.2021.  https://www.bmj.com/content/375/bmj-2021-068302

Public health measures for covid-19. BMJ. 19.11.2021. https://www.bmj.com/content/375/bmj.n2729

Counting the neurological cost of COVID-19. nature reviews neurology. 18.11.2021. https://www.nature.com/articles/s41582-021-00593-7?s=03

Dissecting the early COVID-19 cases in Wuhan. Science. 18.11.2021. https://www.science.org/doi/10.1126/science.abm4454?

Mapping how the 100 billion cells in the brain all fit together is the brave new world of neuroscience. The Conversation. 18.11.2021. https://theconversation.com/mapping-how-the-100-billion-cells-in-the-brain-all-fit-together-is-the-brave-new-world-of-neuroscience-170182

New analyses of two AZD7442 COVID-19 Phase III trials in high-risk populations confirm robust efficacy and long-term prevention. AstraZeneca. 18.11.2021. https://www.astrazeneca.com/content/astraz/media-centre/press-releases/2021/new-analyses-of-two-azd7442-covid-19-phase-iii-trials-in-high-risk-populations-confirm-robust-efficacy-and-long-term-prevention.html?utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=newsAlerts&utm_term=coronavirus&utm_content=2021-11-19&apid=35182891&rvid=36e7b8c23c4809c80789f33a578dd1ee1d782a7186ca0f4d83fca8b14a1a75e7

Multifactorial seroprofiling dissects the contribution of pre-existing human coronaviruses responses to SARS-CoV-2 immunity. Nature. 18.11.2021. https://www.nature.com/articles/s41467-021-27040-x

Do childhood colds help the body respond to COVID?
A mechanism known as ‘original antigenic sin’ protects some people from flu; whether it helps immune reactions to coronaviruses is still unclear.  Nature. 18.11.2021. https://www.nature.com/articles/d41586-021-03087-0?fbclid=IwAR2vyBm4igzgZihWRgE_P3C-Q_SjOW544TPr9itRss8dPsQFZSM9GR0T6F4

Results of COVID-19 Vaccine Effectiveness Studies: An Ongoing Systematic Review. Weekly Summary Tables. International Vaccine Access Center,
Johns Hopkins Bloomberg School of Public Health andWorld Health Organization. 18.11.2021. https://view-hub.org/sites/default/files/2021-11/COVID19%20Vaccine%20Effectiveness%20Transmission%20Impact%20Studies%20-%20Summary%20Tables_20211118_0.pdf

US vaccine rollout was close to optimal at reducing deaths and infections, according to a model comparing 17.5 million alternative approaches. The Conversation. 17.11.2021. https://theconversation.com/us-vaccine-rollout-was-close-to-optimal-at-reducing-deaths-and-infections-according-to-a-model-comparing-17-5-million-alternative-approaches-171656

Covid-19 transmission in fitness centers in Norway – a randomized trial. National Library of Medicine. (BMC Public Health). 16.11.2021. https://pubmed.ncbi.nlm.nih.gov/34789188/

PD-1 blockade counteracts post–COVID-19 immune abnormalities and stimulates the anti–SARS-CoV-2 immune response. JCI Insight. 16.11.2021.  https://insight.jci.org/articles/view/146701/figure/4

Efficacy of FFP3 respirators for prevention of SARS-CoV-2 infection in healthcare workers. eLife. 16.11.2021. https://elifesciences.org/articles/71131

Neutralising antibody titres as predictors of protection against SARS-CoV-2 variants and the impact of boosting: a meta-analysis. Lancet. 15.11.2021.  https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(21)00267-6/fulltext

SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis. Nature Communications. 15.11.2021. https://www.nature.com/articles/s41467-021-26910-8.epdf?

Lehdistötiedote. Valtakunnallinen #TaasMennään-joukkoliikennekampanja siirtyy heikentyneen epidemiatilanteen takia.  12.11.2021. https://www.lvm.fi/-/valtakunnallinen-taasmennaan-joukkoliikenne-kampanja-siirtyy-heikentyneen-epidemiatilanteen-takia-1575633

Increased risk of SARS-CoV-2 reinfection associated with emergence of the Omicron variant in South Africa. medRxiv. 11.11.2021. https://www.medrxiv.org/content/10.1101/2021.11.11.21266068v2

November 11 – 20

COVID-19 tests: Does accuracy vary throughout the day? Medical News Today. 10.11.2021. https://www.medicalnewstoday.com/articles/covid-19-tests-does-accuracy-vary-throughout-the-day?utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=newsAlerts&utm_term=coronavirus&utm_content=2021-11-10&apid=35182891&rvid=36e7b8c23c4809c80789f33a578dd1ee1d782a7186ca0f4d83fca8b14a1a75e7

Israel aloitti kolmannet koronarokotukset ensimmäisenä maailmassa – näin tautitilanne muuttui. Yli neljä miljoonaa israelilaista on saanut jo kolmannen koronapiikin, ja maan koronatilanne näyttää taas hyvältä. Iltalehti. 10.11.2021. https://www.iltalehti.fi/ulkomaat/a/c7b6a42f-c101-4133-8e13-7b5a94a9249b?utm_source=iltalehti.fi&utm_medium=email&utm_campaign=email_il_uutiskirje

Covid-19: Pandemic reduced life expectancy in most developed countries, study finds. BMJ. 10.11.2021. https://www.bmj.com/content/375/bmj.n2750

Covid vaccination to be mandatory for NHS staff in England from spring 2021. BMJ. 10.11.2021.  https://www.bmj.com/content/375/bmj.n2733?=&utm_source=adestra&utm_medium=email&utm_campaign=usage&utm_content=daily&utm_term=text

COVID-19 tests: Does accuracy vary throughout the day?. Medical News Today. 10.11.2021.  https://www.medicalnewstoday.com/articles/covid-19-tests-does-accuracy-vary-throughout-the-day?utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=newsAlerts&utm_term=coronavirus&utm_content=2021-11-10&apid=35182891&rvid=36e7b8c23c4809c80789f33a578dd1ee1d782a7186ca0f4d83fca8b14a1a75e7

Modeling COVID-19 Mortality Across 44 Countries: Face Covering May Reduce Deaths. AJPM. 10.11.2021. https://www.ajpmonline.org/article/S0749-3797(21)00557-2/fulltext

Israel aloitti kolmannet koronarokotukset ensimmäisenä maailmassa – näin tautitilanne muuttui. Yli neljä miljoonaa israelilaista on saanut jo kolmannen koronapiikin, ja maan koronatilanne näyttää taas hyvältä. IL. 10.11.2020. https://www.iltalehti.fi/ulkomaat/a/c7b6a42f-c101-4133-8e13-7b5a94a9249b?utm_source=iltalehti.fi&utm_medium=email&utm_campaign=email_il_uutiskirje

Unvaccinated Texans 40 times as likely to die of covid as those fully vaccinated in 2021, study says. WP. 9.11.2021.   https://www.washingtonpost.com/health/2021/11/09/texas-unvaccinated-deaths-higher-covid/?fbclid=IwAR1NX9H-oGUUHSsZCzmk-XeE3hRWd5ifZ7E3_sCItv2X9tRBOuSMl6zr9gU

Six-month sequelae of post-vaccination SARS-CoV-2 infection: a retrospective cohort study of 10,024 breakthrough infections.  @IanRicksecker, In the words of the study authors, “vaccination does not appear to be protective against .. long-COVID features, arrhythmia, joint pain, type 2 diabetes, liver disease, sleep disorders, and mood and anxiety disorders.” medRxiv. 8.11.2021.  https://doi.org/10.1101/2021.10.26.21265508

COVID-19 Cases and Deaths by Vaccination Status. Texas Department of State Health Services. 8.11.2021. https://documentcloud.adobe.com/link/review?uri=urn:aaid:scds:US:85395206-6268-4cb8-8259-7dc12a039bcb#pageNum=1

Cohort study of Covid-19 vaccine effectiveness among healthcare workers in Finland, December 2020 – October 2021. medRxiv.  8.11.2021.  https://www.medrxiv.org/content/10.1101/2021.11.03.21265791v2

Coronavirus (COVID-19) booster vaccine. NHS. 8.11.2021. ttps://www.nhs.uk/conditions/coronavirus-covid-19/coronavirus-vaccination/coronavirus-booster-vaccine/

Researchers uncover gene that doubles risk of death from COVID-19. University of Oxford. 5.11.2021. https://www.ox.ac.uk/news/2021-11-05-researchers-uncover-gene-doubles-risk-death-covid-19

Pfizer antiviral slashes COVID-19 hospitalizations. Given early in infection, experimental pill prevents severe disease, trial suggests. Science. 5.11.2021.  https://www.science.org/content/article/pfizer-antiviral-slashes-covid-19-hospitalizations?utm_campaign=news_daily_2021-11-08&fbclid=IwAR0AdiPmZUWY0_e6w4bVRQvrONQQ6Wld81CNQcYDa4S-_ZoPZQxHzFHxwB4

SARS-CoV-2 vaccine protection and deaths among US veterans during 2021. Science. 4.11.2021. https://www.science.org/doi/10.1126/science.abm0620

Pfizerin koronalääke osoittautui erittäin tehokkaaksi – Lupahakemus lähtee Yhdysvaltain lääkeviranomaisille.
Yhtiö hakee lääkkeelle erikoislupaa jo ennen kolmannen vaiheen suurta ihmistutkimusta. Mediuutiset. 5.11.2021. https://www.mediuutiset.fi/uutiset/mu/15b7065f-2fb6-4ffb-afc7-0beb1821b71f?ref=newsletter:4f94&utm_source=uutiskirje%40mediuutiset.fi&utm_medium=email&utm_campaign=MU-Uutiskirje-laakari

Remdesivir, Get Out Of The Way: Pfizer’s Antiviral Shines. American Council on Sciences and Health. 5.11.2021. https://www.acsh.org/news/2021/11/05/remdesivir-get-out-way-pfizers-antiviral-shines-15923?fbclid=IwAR1RU9lENChgjcIoNdMAC7b5_cVEOoMrYfYeIT1sl_OnQ7KxNb-Lt7T4i24

WHO varoittaa: Eurooppaan ”tautien talvi” – koronaennätyksiä rikotaan nyt monessa maassa. WHO:n mukaan Eurooppa on pandemian keskus. Iltalehti. 4.11.2021. https://www.iltalehti.fi/ulkomaat/a/e87e81bf-d34e-43f5-95ed-91254d26490c

Rapid assessment of SARS-CoV-2 evolved variants using virus-like particles. Science. 4.11.2021.  https://www.science.org/doi/10.1126/science.abl6184

Prevalence of ongoing symptoms following coronavirus (COVID-19) infection in the UK: 4 November 2021. Estimates of the prevalence of self-reported long COVID and associated activity limitation, using UK Coronavirus (COVID-19) Infection Survey data. Office for National Statistics. 4.11.2021. https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/prevalenceofongoingsymptomsfollowingcoronaviruscovid19infectionintheuk/4november2021

THL:n Mika Salminen: Uusi arvio paluusta normaaliin elämään
Vaikka 80 prosentin rokotuskattavuus saavutetaan tällä viikolla, paluu normaaliin ei voi alkaa. THL:n Terveysturvallisuusosaston johtaja Mika Salminen kertoo nyt kaiken siitä, miltä Suomen tulevaisuus näyttää. Ilta=Sanomet. 3.11.2021. https://www.is.fi/kotimaa/art-2000008374234.html

Are vaccine passports and covid passes a valid alternative to lockdown? BMJ. 3.11.2021. https://www.bmj.com/content/375/bmj.n2571

Kansalaispulssi – 28. kierros. Verkkokysely 27.10.–1.11.2021
15–74-vuotiaat mannersuomalaiset. VNK Strategiaosasto.
3.11.2021. https://valtioneuvosto.fi/documents/10184/49252202/Kansalaispulssi+3.11.2021.pdf/d202b3a1-53a3-6e95-37ee-7461c5bd5154/Kansalaispulssi+3.11.2021.pdf?version=1.1&t=1636110644012&download=true

Russia’s vaccine disinformation has let down its own people
Poor handling has intensified an enduring distrust of state authorities. FT. 3.11.2021. https://www.ft.com/content/dcf6e11c-28f7-4541-b8d9-f91d4825da8a

COVID-19: Antidepressant cuts risk of hospitalization, death by 32%. Medical News Today. 2.11.2021. https://www.medicalnewstoday.com/articles/covid-19-antidepressant-cuts-risk-of-hospitalization-death-by-32?utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=newsAlerts&utm_term=coronavirus&utm_content=2021-11-03&apid=35182891&rvid=36e7b8c23c4809c80789f33a578dd1ee1d782a7186ca0f4d83fca8b14a1a75e7

Nur Spanische Grippe und Aids tödlicher als Corona
Fünf Millionen Menschen sind bislang durch Sars-CoV-2 gestorben, so die offizielle Zahl. Ein Vergleich der Virus-Epidemien unserer Zeit. BaZ. 2.11.2021.  https://www.bazonline.ch/nur-spanische-grippe-und-aids-toedlicher-als-corona-682150625606?utm_source=sfmc&utm_medium=email&utm_campaign=BS_ED_9_ENG_EM_NL_XX_DERABEND_XX_2021-11-022&utm_term=2021-11-02&utm_content=1726982_

A Review and Autopsy of Two COVID Immunity Studies. Brownstone Institute. 2.11.2021. https://brownstone.org/articles/a-review-and-autopsy-of-two-covid-immunity-studies/?s=03

Covid-19: Researcher blows the whistle on data integrity issues in Pfizer’s vaccine trial. BMJ 2.11.2021. https://www.bmj.com/content/375/bmj.n2635

Risk factors for developing COVID-19: a population-based longitudinal study (COVIDENCE UK). BMJ Thorax. 2.11.2021. https://thorax.bmj.com/content/early/2021/11/02/thoraxjnl-2021-217487

Global Covid-19 deaths surpass five million. CNN Workd. 1.11.2021. https://edition.cnn.com/2021/11/01/world/covid-19-5-million-deaths-globally-intl-hnk/index.html?utm_term=1635762508890005700fe1b99&utm_source=cnn_Five+Things+for+Monday%2C+November+1%2C+2021&utm_medium=email&bt_ee=SgX8PRGbWYAjEV7myThR%2FnkIQM4WcqXhocXrTUNqsmweh92Y21i2BGgsGBh5quHT&bt_ts=1635762508892

Deaths involving COVID-19 by vaccination status, England: deaths occurring between 2 January and 24 September 2021. Weekly age-standardised mortality rates and age-specific rates for deaths involving COVID-19 by vaccination status; deaths occurring between 2 January and 24 September 2021 in England. Office for National SStatistics. 1.11.2021. https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/bulletins/deathsinvolvingcovid19byvaccinationstatusengland/deathsoccurringbetween2januaryand24september2021?fbclid=IwAR0RhDFqc3NYS4NulNhe1Y43fLQaFCNxxJ_3ravBHIEYdbKTByjuvEE8xYU

November 1-10

Taloustieteilijät: Ilman koronasulkuja taloudellisia tappioita ja kuolleita olisi tullut paljon enemmän. Suurin osa kulutuksen laskusta on tullut ihmisten varovaisuudesta, ei yhteiskunnan suluista, Ylen haastattelemat koronatutkimukseen perehtyneet taloustieteilijät arvioivat. Norjassa tehdyn tutkimuksen mukaan kuolleita olisi kymmenkertainen määrä Ruotsin kaltaisella koronapolitiikalla. YLE Uutiset. 31.10.2021. https://yle.fi/uutiset/3-12165691

THL ehdottaa koronapassia sote-työntekijöille – näin kommentoivat kansanedustajat terveysalalta
Iltalehti kysyi kolmelta sote-taustaiselta kansanedustajalta, mitä mieltä he ovat THL:n ehdotuksesta käyttää koronapassia sote-alan työntekijöihin. Iltalehti. 31.10.2021. https://www.iltalehti.fi/politiikka/a/34c3f822-cbe5-48f5-9cd6-f929ef16507e?utm_source=iltalehti.fi&utm_medium=email&utm_campaign=email_il_uutiskirje

The Removal of Airborne Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Other Microbial Bioaerosols by Air Filtration on Coronavirus Disease 2019 (COVID-19) Surge Units [Kun hepa-ilmanpuhdistimet olivat päällä, ilmasta ei voitu tunnistaa koronavirusta. Kun ne sammutettiin, virusta löytyi taas ilmasta]. Clinical Infectious Diseases. 30.10.2021. https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciab933/6414657?login=false

RKI warnt vor Superspreading: 8-Punkte-Check zeigt, wann das Risiko besonders hoch ist. Das Robert-Koch-Institut warnt vor weiter steigenden Corona-Zahlen – vor allem durch Kontakte in Innenräumen. Um besser einschätzen zu können, wie hoch das Risiko in welcher Umgebung ist, hat Virologe Hendrik Streeck gemeinsam mit Aerosol-Forschern und Lungenmediziner den ”Lufthygiene”-Guide veröffentlicht. Focus. 30.10.2021. https://m.focus.de/gesundheit/coronavirus/virologe-streeck-und-aerosol-experten-lufthygiene-check-wo-die-corona-gefahr-hoch-ist-und-wo-nicht_id_24340093.html

Vaaran paikka. Virustutkimus auttaa suojelemaan terveyttä. Joskus virukset karkaavat laboratorio-onnettomuuden seurauksena. Wuhanissa Kiinassa suunniteltiin riskialtista koetta, jolla olisi voinut olla vakavia seurauksia. YLE-Uutiset. 30.10.2021. https://yle.fi/uutiset/3-12156805

Suomessa ensimmäiset Delta plus -löydökset – tämä aiempaa tartuttavammasta koronamuunnoksesta tiedetään.
Terveyden ja hyvinvoinnin laitoksen tietojen mukaan ensimmäiset löydökset Delta plus -variantista tulivat jo elokuussa. Viranomaiset eivät kerro yksilönsuojan takia paikkakuntia, kun tartuntoja on alle viisi. MTV-Uutiset. 29.10.2021. https://www.mtvuutiset.fi/artikkeli/suomessa-ensimmaiset-delta-plus-loydokset-tama-aiempaa-tartuttavammasta-koronamuunnoksesta-tiedetaan/8276114#gs.io00h0

Community transmission and viral load kinetics of the SARS-CoV-2 delta (B.1.617.2) variant in vaccinated and unvaccinated individuals in the UK: a prospective, longitudinal, cohort study. Lancet Infectious Diseases. 29.10.2021. https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00648-4/fulltext

Contact and SARS-CoV-2 Infections Among College Football Athletes in the Southeastern Conference During the COVID-19 Pandemic. JAMA. 29.10.2021. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2785602?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102921

Effectiveness of a third dose of the BNT162b2 mRNA COVID-19 vaccine for preventing severe outcomes in Israel: an observational study. Lancet. 29.10.2021. DOI:https://doi.org/10.1016/S0140-6736(21)02249-2

Suomessa ensimmäiset Delta plus -löydökset – tämä aiempaa tartuttavammasta koronamuunnoksesta tiedetään. Terveyden ja hyvinvoinnin laitoksen tietojen mukaan ensimmäiset löydökset Delta plus -variantista tulivat jo elokuussa. Viranomaiset eivät kerro yksilönsuojan takia paikkakuntia, kun tartuntoja on alle viisi. MTV. 29.10.2021.  https://www.mtvuutiset.fi/artikkeli/suomessa-ensimmaiset-delta-plus-loydokset-tama-aiempaa-tartuttavammasta-koronamuunnoksesta-tiedetaan/8276114#gs.eosbkn

The plexiglass barrier problem. Justin Ling: Vaccines, masks and ventilation are working. So why do governments keep doubling-down on the measures that don’t effectively stop COVID? MacLean’s 29.10.2021. https://www.macleans.ca/society/health/the-plexiglass-barrier-problem/

We must call out childism in covid-19 policies. BMJ. 29.10.2021. https://www.bmj.com/content/375/bmj.n2641

Community transmission and viral load kinetics of the SARS-CoV-2 delta (B.1.617.2) variant in vaccinated and unvaccinated individuals in the UK: a prospective, longitudinal, cohort study. Lancet. 29.10.2021.  https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00648-4/fulltext#%20

Did ‘Eat Out to Help Out’ increase COVID-19 cases in England? Medical News Today. 28.10.2021. https://www.medicalnewstoday.com/articles/did-eat-out-to-help-out-increase-covid-19-cases-in-england?utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=newsAlerts&utm_term=coronavirus&utm_content=2021-11-01&apid=35182891&rvid=36e7b8c23c4809c80789f33a578dd1ee1d782a7186ca0f4d83fca8b14a1a75e7

Yökoulusta levinneet koronatartunnat hätkähdyttivät ihmisoikeusjuristin – Martin Scheinin: ”Pidän aiheellisena, että asiassa tehdään tutkintapyyntö”
Ihmisoikeusjuristi Martin Scheininin mukaan viranomaisten mahdolliset laiminlyönnit tartuntatautilain noudattamisessa on syytä punnita oikeudessa. Lappajärvellä Etelä-Pohjanmaalla koronatartunnat levisivät alakoululaisten yökoulussa. YLE Uutiset. 27.10.2021. https://yle.fi/uutiset/3-12162621

Immunocompromised may need a fourth Covid-19 shot, CDC says. CNN Health. 27.10.2021. https://edition.cnn.com/2021/10/26/health/covid-19-fourth-dose-for-the-immunocompromised/index.html

Noin 20-vuotiaat rokottamattomat nuoret joutuneet koronan takia keskussairaalaan – keuhkot huonossa kunnossa. Ilkka-Pohjalainen kertoo, että Seinäjoen keskussairaalassa on tällä viikolla hoidettu muutamaa vasta noin 20-vuotiasta koronapotilasta, joiden keuhkot ovat huonossa kunnossa. IS. 27.10.2021. https://www.is.fi/kotimaa/art-2000008350962.html

Breakthrough infections can lead to long COVID; genes may explain critical illness in young, healthy adults. Reuters. 27.10.2021. https://www.reuters.com/business/healthcare-pharmaceuticals/breakthrough-infections-can-lead-long-covid-genes-may-explain-critical-illness-2021-10-27/

Finland’s Success in Combating Covid-19: Mastery, Miracle or Mirage? SSERN. 27.10.2021. https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3909237#

F.D.A. Panel Recommends Covid Shots for Children 5 to 11
Covid-19 was “the eighth-highest killer of kids in this age group over the past year,” said a C.D.C. official in favor of broader authorization. NYT. 26.10.2021. https://www.nytimes.com/2021/10/26/us/fda-pfizer-covid-vaccine-kids.html?smid=tw-share

Ansiktsskydd behövs fortfarande. HBL. 26.10.2021. https://www.hbl.fi/artikel/ansiktsskydd-behovs-fortfarande/

Type of ultraviolet light most effective at killing coronavirus is also the safest to use around people. The Conversation. 26.10.2021. https://theconversation.com/type-of-ultraviolet-light-most-effective-at-killing-coronavirus-is-also-the-safest-to-use-around-people-169602?utm

Terveyden­huollon työnantajalla tulisi olla oikeus tietää työntekijän rokotus­suojasta, vaatii Lääkäri­liitto – ”Olisi helpompaa, jos tiedon näkisi kysymättä”, sanoo Husin Ruotsalainen. Husin apulaisylilääkäri Eeva Ruotsalaisen mukaan on selvä potilasturvallisuusriski, jos esimerkiksi rokottamaton työntekijä tuo tartuntoja hoivakotiin. HE. 25.10.2021. https://www.hs.fi/kotimaa/art-2000008356424.html?share=661dc8d4856bafc4d6eaff0d8f33925b

Professori varoittaa keskustelun kärjistymisestä: Nykyinen puhetapa voi lisätä rokotus­vastaisuutta. Rokotusta vaille jääminen ei ole aina tietoisen harkinnan tulos, sanoo professori Nelli Hankonen. HS. 25.10.2021.  https://www.hs.fi/hyvinvointi/art-2000008349588.html?share=3f242d9d3e6a5400d076f918969a2de2

Evaluation of the relative virulence of novel SARS-CoV-2 variants: a retrospective cohort study in Ontario, Canada. CMAJ. 25.10.2021. https://www.cmaj.ca/content/193/42/E1619

Effectiveness of Covid-19 Vaccination Against Risk of Symptomatic Infection, Hospitalization, and Death Up to 9 Months: A Swedish Total-Population Cohort Study. Lancet. 25.10.2021. https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3949410

SARS-CoV-2 infects human adipose tissue and elicits an inflammatory response consistent with severe COVID-19, BioRxiv. 24.10.2021.  https://www.biorxiv.org/content/10.1101/2021.10.24.465626v1

Health leaders accuse ministers of bungling rollout of UK Covid booster jab
Vaccine drive described as ‘fragmented’ with half the people eligible for third dose yet to come forward. FT. 22.10.2021.  https://amp.ft.com/content/1f57838a-24d2-40d5-b314-2d8345a6e001?__twitter_impression=true

Suomi purki koronarajoituksia, vaikka THL:n käyrät varoittivat uhkaavista seurauksista – tautiekologi: ”Masentavinta, että meni juuri niin kuin ajateltiin”.  THL mallinsi elokuussa, miten sairaalahoito kuormittuisi, jos rajoituksia purettaisiin 80 prosentin rokotekattavuuden koittaessa. Hoidon tarve olisi noussut merkittävästi. Rajoitukset purettiin, kun kattavuus oli vielä selvästi vähemmän, noin 70 prosenttia. YLE-Uutiset. 22.10.2021. https://yle.fi/uutiset/3-12155829?utm_source=newsletter&utm_medium=email&utm_campaign=newsdaily&utm_content=2021-10-23

Safe traveling in public transport amid COVID-19. Science. 22.10.2021. https://www.science.org/doi/10.1126/sciadv.abg3691?utm_campaign=SciMag&utm_source=Social&utm_medium=Twitter

Assessment of Cognitive Function in Patients After COVID-19 Infection. JAMA.  22.10.2021. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2785388?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102221

The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells. Nature Neuroscience. 21.10.2021.  https://www.nature.com/articles/s41593-021-00926-1

Pfizer boosters show 95.6% efficacy against Covid, study finds. Results hailed as ‘important’ but duration of protection still unknown. FT. 21.10.2021.  https://amp.ft.com/content/d4e58d38-37d6-40cd-9d72-6b9bfd0a3683?

PFIZER AND BIONTECH ANNOUNCE PHASE 3 TRIAL DATA SHOWING HIGH EFFICACY OF A BOOSTER DOSE OF THEIR COVID-19 VACCINE. Pfizer. 21.11.2021. https://www.pfizer.com/news/press-release/press-release-detail/pfizer-and-biontech-announce-phase-3-trial-data-showing

The American founders didn’t believe your sacred freedom means you can do whatever you want – not even when it comes to vaccines and your own body. The Conversation. 21.10.2021. https://theconversation.com/the-american-founders-didnt-believe-your-sacred-freedom-means-you-can-do-whatever-you-want-not-even-when-it-comes-to-vaccines-and-your-own-body-169924?utm

Voisiko Suomeen tulla rokotepakko? Oikeusoppineet hämmästelevät, miksi kissa ei ole jo pöydällä. Rokotepakko on vaikeampi asia poliittisesti kuin juridisesti. Rokotevelvoitteen käyttöönotto vaatisi lääketieteellistä arviointia ja poliittista keskustelua. Rokotevelvoitteen käyttöönotto vaatisi lääketieteellistä arviointia ja poliittista keskustelua. Rokotevelvoitteen käyttöönotto vaatisi lääketieteellistä arviointia ja poliittista keskustelua. Iltalehti. 21.10.2021. https://www.iltalehti.fi/kotimaa/a/ea67d28e-2250-4cd3-b6a4-303cdd357acb?utm

October 21-31

Moscow orders unvaccinated over-60s to stay home for 4 months as Russia’s Covid-19 crisis deepens. CNN World. 20.10.2021. https://edition.cnn.com/2021/10/20/europe/russia-elderly-stay-home-order-record-deaths-intl/index.html?utm

Koulu pantiin jatkuviin koronatesteihin: Yllätys lasten tartunnoissa. Tutkimuksen perusteella lasten rooli taudin levittäjinä voi olla oletettua suurempi. Verkkouutiset. 20.10.2021. https://www.verkkouutiset.fi/koulu-pantiin-jatkuviin-koronatesteihin-yllatys-lasten-tartunnoissa/#53d13ff6

COVID-19 pandemic drove flu to historic lows, and may have eliminated one virus type completely. ABC Science News. 20.10.2021.  https://amp.abc.net.au/article/100546836?__twitter_impression=true

Miten koronan torjuntaa pitäisi mitata? Professorin (Lillrank) laskelman mukaan pelastetut elinvuodet ovat maksaneet kymmeniä kertoja kohtuuhintaa enemmän. Koronaa on torjuttu kohtuuttomalla hinnalla, kun käyttöön otettiin laajat sulkutoimet, professori Paul Lillrank sanoo. Koronan kustannusten mittaaminen on kuitenkin vaikeaa, koska emme tiedä mitä olisi tapahtunut, jos olisimme tehneet toisin. YLE-Uutiset. 20.10.2021. https://yle.fi/uutiset/3-12150546?utm_source=newsletter&utm_medium=email&utm_campaign=ylefi&utm_content=2021-10-20

Covid-19-tapaukset lisääntyvät koulujen avautuessa – Etenkin silloin, kun opettajat ja oppilaat eivät käytä maskeja. Koulut lisäävät yhteisön tartuntoja, mutta hyvä uutinen on, että suhteellisen yksinkertaiset lieventävät toimenpiteet voivat tehdä kouluista paljon turvallisempia paikkoja, kirjoittaa Tutkijalta-palstalla epidemiologi ja biostatistikko Zoë Hyde Länsi-Australian yliopistosta. TM. 20.10.2021. https://tekniikanmaailma.fi/covid-19-tapaukset-lisaantyvat-koulujen-avautuessa-etenkin-silloin-kun-opettajat-ja-oppilaat-eivat-kayta-maskeja/

HS: Teho-osaston lääkäriltä lohduton arvio tulevasta koronatilanteesta – ”Jos meininki jatkuu tällaisena…” Turun yliopistollisen sairaalan osastonlääkäri Jussi Heiro antaa Helsingin Sanomissa lohduttoman arvionsa tulevasta koronatilanteesta. IS. 20.10.2021. https://www.is.fi/turun-seutu/art-2000008345611.html

The association of opening K–12 schools with the spread of COVID-19 in the United States: County-level panel data analysis. PNAS. 19.10.2021. https://www.pnas.org/content/118/42/e2103420118

Without Covid-19 jab, ‘reinfection may occur every 16 months’
Reports grow of repeat infection as experts warn prevalence among school pupils puts older people at risk. Guardian. 19.10.2021. https://www.theguardian.com/world/2021/oct/19/without-covid-19-jab-reinfection-may-occur-every-16-months-say-scientists

Piispa Teemu Laajasalo kannusti ihmisiä ottamaan rokotteen – yli 200 ihmistä erosi kirkosta. Eilen kirkosta erosi 242 ihmistä. Iltalehti. 19.10.2021. https://www.iltalehti.fi/kotimaa/a/ce2d6484-f917-41bb-af07-6b7cdf4b9245?utm

Covid-19: Silencing health workers, researchers, and journalists caused unnecessary deaths, says Amnesty. 19.10.2021. https://www.bmj.com/content/375/bmj.n2552?=&utm_source=adestra&utm_medium=email&utm

Excess risk and clusters of symptoms after COVID-19 in a large Norwegian cohort. medRxiv. 18.10.2021. https://www.medrxiv.org/content/10.1101/2021.10.15.21265038v1.full.pdf

Effectiveness of public health measures in reducing the incidence of covid-19, SARS-CoV-2 transmission, and covid-19 mortality: systematic review and meta-analysis. BMJ. 18.11.2021. https://www.bmj.com/content/375/bmj-2021-068302

swedish study shows covid vaccines drop below zero efficacy on spread by about 200 days. protection from severe covid dropped as well. bad cattitude. 18.10.2021. https://boriquagato.substack.com/p/swedish-study-shows-covid-vaccines

Nelli Hankonen blog: Albertan koronasyksy 2021. 18.10.2021. https://blogs.helsinki.fi/nhankone/2021/10/18/albertan-koronasyksy-2021/

Emeritusprofessori esittää Suomeen Italian ja Ranskan tyylistä ’de facto’ rokotuspakkoa. Käytännössä rokotuspakko voidaan Matti Jantusen mukaan toteuttaa samalla mallilla kuin esimerkiksi Italiassa ja Ranskassa. Mediuutiset. 18.10.2021. https://www.mediuutiset.fi/uutiset/mu/4646944e-c239-436d-8ce6-b5bf63cc436e?ref=newsletter:434f&utm

Mask-wearing linked to 53% cut in Covid incidence, global study finds. Researchers said results highlight the need to continue with face coverings, social distancing and handwashing alongside vaccine programmes. Guardian. 17.10.2021. https://www.theguardian.com/world/2021/nov/17/wearing-masks-single-most-effective-way-to-tackle-covid-study-finds?CMP=Share_iOSApp_Other

TERVEYSPSYKOLOGIA: Koronataistelu muuttuu sissisodaksi. Matti TJ Heino blog. 17.10.2021. https://mattiheino.com/2021/10/17/sissisota/

Nyt puhuu teho­hoito­lääkäri: ”Emme jaksa enää”. Tehohoitolääkärin mukaan hoitohenkilökunta on aivan loppu.
THL on julkaissut rokotekampanjavideoita – kehottavat ihmisiä hakemaan rokotteen. Iltalehti. 17.10.2021. https://www.iltalehti.fi/koronavirus/a/35a746af-e1df-4212-8680-2a26e4636375

 

Victoria and NSW schools are reopening amid Covid outbreaks – what can be learned from overseas? In Victoria, once the lockdown is lifted, all children in year 3 and above will be required to wear masks indoors. Experts say there are important lessons for Australia in order to reduce the rate of transmission and hospitalisation. Guardian. 16.10.2021.  https://www.theguardian.com/australia-news/2021/oct/17/victoria-and-nsw-schools-are-reopening-amid-covid-outbreaks-what-can-be-learnt-from-overseas?utm_term=Autofeed&CMP=twt_gu&utm_medium&utm_source=Twitter#Echobox=1634411450

Asiantuntija ryöpyttää Suomen päättäjiä: ”Onko meillä siis tyhmempi kansa josta osa ansaitseekin sairastaa ja kuolla?” Tuuli Lappalaisen mukaan sekä viranomaiset että poliitikot ovat antaneet ennenaikaisia ja ylioptimistisia lupauksia, ja niiden peruminen nyt tekee kipeää. Uusi Suomi. 16.10.2021.  https://www.uusisuomi.fi/uutiset/us/b0aaf526-55e4-485c-af62-0e83d3d04b13?ref=twitter:286d

Lääkäriltä suorat sanat: Kohta nämä hoidetaan itkun kanssa.
Tutkijalääkäri sanoo olevansa äärimmäisen pettynyt poliittiseen johtamiseen.Verkkouutiset. 16.10.2021. https://www.verkkouutiset.fi/laakarilta-suorat-sanat-kohta-nama-hoidetaan-itkun-kanssa/#b7eaa73f

UK falls behind European peers in battle against Covid ahead of winter
Deaths and hospital admissions remain stubbornly high in Britain as the continent reports record lows. FT. 16.10.2021. ttps://amp.ft.com/content/34582534-4510-4d45-bcba-2f9e04005309?__twitter_impression=true

Virhekäsitykset ja yksinkertaistukset johtavat meitä harhaan: 10 julkisen koronakeskustelun kampittajaa. Osa 2. Blogi. CitizenShield. 15.10.2021. https://citizenshield.fi/2021/10/15/virhekasitykset-ja-yksinkertaistukset-johtavat-meita-harhaan-10-julkisen-koronakeskustelun-kampittajaa/

K-12 schools without mask mandates in Michigan saw 62% more coronavirus spread. Detroit Free Press. 15.10.2021. https://amp.freep.com/amp/8422532002?__twitter_impression=true

Suomi värjäytyi punaiseksi Euroopan tauti­keskuksen kartalla – matkustamista ei suositella. Kahden viime viikon aikana Suomessa on raportoitu 7 763 uutta koronatartuntaa, mikä on 1 632 tartuntaa enemmän kuin edellisten kahden viikon aikana. IS. 15.10.2021. https://www.is.fi/kotimaa/art-2000008336966.html

Coronavirus (COVID-19) Infection Survey, UK: 15 October 2021
Estimates for England, Wales, Northern Ireland and Scotland. This survey is being delivered in partnership with the University of Oxford, University of Manchester, Public Health England and Wellcome Trust. This study is jointly led by the ONS and the Department for Health and Social Care (DHSC) working with the University of Oxford and Lighthouse laboratory to collect and test samples. Office of National Atatistics. 15.10.2021. https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/coronaviruscovid19infectionsurveypilot/15october2021

How many lives have coronavirus vaccines saved? We used state data on deaths and vaccination rates to find out. The Conversation. 15.10.2021. https://theconversation.com/how-many-lives-have-coronavirus-vaccines-saved-we-used-state-data-on-deaths-and-vaccination-rates-to-find-out-169513?utm

FDA vaccine advisers recommend emergency use authorization for booster dose of Moderna’s Covid-19 vaccine. CNN Health. 15.10.2021. https://edition.cnn.com/2021/10/14/health/fda-vaccine-advisers-moderna-thursday/index.html?utm

Covid-19 Breakthrough Infections in Vaccinated Health Care Workers. @IanRicksecker, But if you’re counting on vaccination to feel safe, there’s even more bad news. A study of Israel healthcare workers found that “Most breakthrough cases were mild or asymptomatic, although 19% had persistent symptoms (>6 weeks).” N MEngl J Med. 14.10.2021.  https://doi:10.1056/NEJMoa2109072

Covid-19: Fatal errors, not fatalism, created UK’s public health disaster. BMJ. 14.10.2021. https://www.bmj.com/content/375/bmj.n2497/rapid-responses

Covid-19 Breakthrough Infections in Vaccinated Health Care Workers. NEJM. 14.10.2021. https://www.nejm.org/doi/full/10.1056/NEJMoa2109072

Covid and flu: what do the numbers tell us about morbidity and deaths? BMJ. 14.11.2021. https://www.bmj.com/content/375/bmj.n2514?=&utm_source=adestra&utm_medium=email&utm_campaign=usage&utm_content=daily&utm_term=text

Children could be dangerous carriers of virus. Study finds kids to be potential spreaders of COVID-19 and emerging variants.  Harvard Gazette. 14.10.2021.  https://news.harvard.edu/gazette/story/2021/10/study-confirms-kids-as-spreaders-of-covid-19-and-emerging-variants/

A public health strategy for SARS-CoV-2, grounded in science, should guide Swiss schools through the coming winter. Swiss Medical Weekly. 14.10.2021.  https://smw.ch/article/doi/SMW.2021.w30086

Molnupiravir vs. COVID-19: Will the drug live up to the hype?
In the search for effective COVID-19 treatments, many drugs have failed to live up to their early promise. In a recent trial, seen as an important advance, the oral antiviral drug molnupiravir halved the risk of hospital admissions and deaths from COVID-19. Medical News Today explored the evidence to see whether this optimism is justified. Medical News Today. 14.10.2021.  https://www.medicalnewstoday.com/articles/molnupiravir-vs-covid-19-will-the-drug-live-up-to-the-hype?utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=MNT%20Daily%20News&utm_content=2021-11-06&apid=32395010&rvid=348b31007bc4905a3c503d64d5572c0dac87e7263eba83389e708a2774ce1afc

Koronapotilaiden sairaalahoito tulisi järjestää uudella tavalla. Jos jatkamme nykyisellä tavalla, muiden sairauksien hoitovelka kasvaa. HS. 14.10.2021. https://www.hs.fi/mielipide/art-2000008329522.html?share=88fac73056eeaf8accb772a13979fe12

SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro. MDPI. 13.10.2021.  https://www.mdpi.com/1999-4915/13/10/2056/htm?fbclid=IwAR1Dhvhw7sYLQSIe5Ll62ERQGvyITyASRIpimMfEmVN7He5e29ZeXgxwXLU

Rokoteasian­tuntijat pohtivat kolmatta rokote­kierrosta tänään – THL:n Nohynek: Tulee miettiä, onko lisä­annoksen terveys­hyöty oikeassa suhteessa hintaan. THL:n alainen Kansallinen rokotus­asiantuntija­ryhmä (Krar) kokoontuu pohtimaan kolmansia koronarokoteannoksia keskiviikkona. HS. 13.10.2021. https://www.hs.fi/kotimaa/art-2000008323890.html?s=03

A cross-sectional analysis of meteorological factors and SARS-CoV-2 transmission in 409 cities across 26 countries. Nature Communications. 13.10.2021. https://www.nature.com/articles/s41467-021-25914-8

Husin ylilääkäri kertoo, keitä sairaaloissa nyt koronataudin vuoksi hoidetaan – ”Rokotukset ovat edenneet huonosti muiden kuin nuorimpien kohdalla”
HS:n uusi grafiikka seuraa rokottamattomien osuutta sairaaloissa. HS. 13.10.2021. https://www.hs.fi/kaupunki/art-2000008328276.html?share=591c82ab6b86a7f0a3d744187315dfbf

Think a mild case of COVID-19 is no big deal? Think again. New research shows concerning effects of the virus, even in asymptomatic cases. Colorado Newsline. 13.10.2021. https://coloradonewsline.com/2021/10/13/mild-case-of-covid-19-no-big-deal-think-again/

In Conversation: The neurocognitive impact of long COVID
For many people, long COVID has associations with serious neurological and neurocognitive impairments, a phenomenon sometimes known as neuro-COVID. Why does this happen, and who is most at risk? In this Special Feature and podcast, we speak to two researchers and a person with lived experience of neuro-COVID to find out more. Medical News Today. 13.10.2021.  https://www.medicalnewstoday.com/articles/long-covid-brain-fog-what-do-we-know-about-the-neurocognitive-impact?utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=MNT%20Daily%20News&utm_content=2021-11-06&apid=32395010&rvid=348b31007bc4905a3c503d64d5572c0dac87e7263eba83389e708a2774ce1afc

Kun sairaala­hoidon tarve kasvoi keväällä tällaiseksi, hallitus julisti ”sulkutilan” – Voiko Marin vielä perääntyä yhteis­kunnan avaamisesta? Pahenevasta tautitilanteesta huolimatta hallituksella on korkea kynnys ajaa kireämpiä rajoituksia. Koronapassi voi tulla laajasti käyttöön vain, jos rajoituksia kiristetään. HS. 12.10.2021. https://www.hs.fi/politiikka/art-2000008325861.html?share=1ee867d6a284bfce9b7b6b71e4265abd

Maailmalla koronalääkettä tilataan jo vauhdilla, Suomessa ei vieläkään – Uhkana on lääkkeiden tuleva saatavuus. Koronalääkkeen myyntiin tulosta on ollut tietoja ilmassa jo pitkään. Suomessa tilanteeseen ei ole nopeasti havahduttu. Mediuutiset. 12.10.2021. https://www.mediuutiset.fi/debatti/maailmalla-koronalaaketta-tilataan-jo-vauhdilla-suomessa-ei-vielakaan-uhkana-on-laakkeiden-tuleva-saatavuus/2eb405b1-9d16-4610-a7cf-8edd9b2f39ad

Your Wednesday Briefing. A damning report on Britain’s virus response. NYT. 13.10.2021.

COVID lesson: trust the public with hard truths. When governments assume that people will panic, that exacerbates the pandemic. Nature 12.10.2021. https://www.nature.com/articles/d41586-021-02758-2?fbclid=IwAR2vAE-gZRvXkhO1aEXj2A56im8qi81qSQWPyNrorh40JmautC5ywUrftJA

‘The real problem is the repetition of mistakes’: scientists react to Covid inquiry. Senior figures say failure to prevent second wave was inexcusable given what was known about the virus. Guardian. 12.10.2021.  https://www.theguardian.com/world/2021/oct/12/the-real-problem-is-the-repetition-of-mistakes-scientists-react-to-covid-enquiry?CMP=Share_iOSApp_Other

Covid response ‘one of UK’s worst ever public health failures’.
Early handling and belief in ‘herd immunity’ led to more deaths, Commons inquiry finds. Guardian. 12.10.2021.  https://www.theguardian.com/politics/2021/oct/12/covid-response-one-of-uks-worst-ever-public-health-failures?CMP=Share_iOSApp_Other

What the Future May Hold for the Coronavirus and Us
Viral evolution is a long game. Here’s where scientists think we could be headed. NYT. 12.10.2021.

Infektiolääkärin epätoivoinen vetoomus koronarokotusten puolesta: ”Hetken näytti hyvältä ja melkein juhlittiin, mutta nyt laivan pohja vuotaa”. Tampereen yliopistollisen keskussairaalan infektiolääkäri kertoo MTV Uutisille rokottamattomien vaikeasta koronatilanteesta. Syyskuussa lähes 80 prosenttia sairaalahoidossa olevista oli rokottamattomia. Lääkäri Reetta Huttusen mukaan hätkähdyttävää on, että merkittävä osuus sairaalaan joutuvista potilaat ei ole iäkkäitä, vaan nuoria tai keski-ikäisiä. MTV-Uutiset. 12.10.2021. https://www.mtvuutiset.fi/artikkeli/infektiolaakarin-epatoivoinen-vetoomus-koronarokotusten-puolesta-hetken-naytti-hyvalta-ja-melkein-juhlittiin-mutta-nyt-laivan-pohja-vuotaa/8262410

Selvitys: Britannia aloitti korona­sulun liian myöhään, mikä oli merkittävä kansan­terveydellinen epä­onnistuminen maan historiassa. Raportin mukaan tämä oli yksi merkittävimmistä kansanterveydellisistä epäonnistumisista maan historiassa. HS. 12.10.2021.  https://www.hs.fi/ulkomaat/art-2000008326330.html?share=011911d95bd7a841169809f72bf1e2f8

How did we get here: what are droplets and aerosols and how far do they go? A historical perspective on the transmission of respiratory infectious diseases. The Royal Society. 12.10.2021. https://doi.org/10.1098/rsfs.2021.0049

Transmission of SARS-CoV-2 After COVID-19 Screening and Mitigation Measures for Primary School Children Attending School in Liège, Belgium. JAMA. 12.10.2021. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2784812

FDA scientists neutral on Moderna Covid-19 vaccine booster ahead of key meeting. STAT. 12.10.2021. https://www.statnews.com/2021/10/12/fda-scientists-moderna-covid-vaccine-booster/#:~:text=Events-,FDA%20scientists%20neutral%20on%20Moderna%20Covid%2D19,booster%20ahead%20of%20key%20meeting&text=Food%20and%20Drug%20Administration,vaccine%20in%20documents%20released%20Tuesday.

Covid-19: Government’s handling of pandemic had “big mistakes,” MPs say. BMJ 12.10.2021. https://www.bmj.com/content/375/bmj.n2487?=&utm

Covid response ‘one of UK’s worst ever public health failures’. Early handling and belief in ‘herd immunity’ led to more deaths, Commons inquiry finds. Guardian. 12.10.2021.  https://www.theguardian.com/politics/2021/oct/12/covid-response-one-of-uks-worst-ever-public-health-failures

Lessons for all from the UK’s Covid mishandling. Politicians and scientists succumbed to a flawed, fatalistic groupthink. FT. 12.10.2021. https://amp.ft.com/content/6369ab78-19ec-4a81-858d-a5f318496306?__twitter_impression=true

Frequency of Neurologic Manifestations in COVID-19. A Systematic Review and Meta-analysis. Neurology. 11.10.2022. https://n.neurology.org/content/97/23/e2269

Covid-19: Is New Zealand’s switch in policy a step forward or a retreat?. BMJ. 11.10.2021. https://www.bmj.com/content/375/bmj.n2476?=&utm_source=adestra&utm_medium=email&utm

Life-saving COVID Drug Regeneron in Israel – but Most Patients Won’t Take It. Some Israelis are COVID anti-vaxxers who distrust Regeneron, but others just don’t see the need or are talked out of it at the last moment. 11.10.2021. https://www.haaretz.com/israel-news/life-saving-covid-wonder-drug-comes-to-israel-but-most-patients-won-t-take-it-1.10282942?utm

Kouvolan koululaisille tuli helpotuksen päivä, kun maskeja ei enää tarvitse käyttää – suurin askel kuitenkin vielä odottaa.
Kouvolassa on tänään maanantaina luovuttu koulujen ja päiväkotien maskisuosituksesta. Ainakin ensimmäisenä päivänä kasvomaski vielä oli monen yllä.. YLE-Uutioset 11.10.2021. https://yle.fi/uutiset/3-12138579

October 11-20

Here’s what Bay Area doctors say about how COVID affects the brain. San Francisco Chronicle. 10.10.2021. https://www.sfchronicle.com/health/article/How-COVID-affects-the-brain-Bay-Area-doctors-16520440.php

Korona vie yhä enemmän sairaalaan: Satakunnassa joudutaan erityisjärjestelyihin. Hoitoon joutuvat ovat valtaosin rokottamattomia. Alle 60-vuotiaita lähes puolet. Kokemäkijokilaakson Uutiset. 10.10.2021. https://www.kokemaenjokilaakso.fi/2021/10/10/korona-vie-yha-enemman-sairaalaan-satakunnassa-joudutaan-erityisjarjestelyihin/

Kraftig ökning av psykisk ohälsa under pandemin. Dagens Nyheter. 10.10.2021. https://www.dn.se/vetenskap/kraftig-okning-av-psykisk-ohalsa-under-pandemin/

Sanna Marin otti riskin, joka näyttää toteutuneen – Tehohoidon ”kriittinen piste” alkaa lähestyä. Sanna Marinin hallitus purki viikko sitten isosti koronarajoituksia ja sen jälkeen tautiluvut kohosivat. Riski näyttää realisoituneen, mutta seuraako tästä rajoitusten palauttamisia, mistä STM jo vihjaisi? Viranomaiset ja pääministeri antavat nyt varsin erilaista viestiä tilanteesta. Mediuutiset. 9.10.2021. https://www.mediuutiset.fi/uutiset/mu/5e432005-aff9-4eb2-8e59-25167af51d64?utm_term=Autofeed&utm_medium=Social&utm_source=Twitter#Echobox=1633764599

Latviassa julistettiin kolmen kuukauden poikkeustila koronan takia. Kyseessä on kolmas kerta, kun Latviassa otetaan käyttöön poikkeustila koronapandemian takia. Poikkeustila koskee erityisesti rokottamattomia. HS. 9.10.2021. https://www.hs.fi/ulkomaat/art-2000008321748.html

Meilahden koronapotilaiden tehohoitopaikat ovat loppumassa – rokottamattomien asenne herättää tuskaa linjajohtajassa: ”En enää keksi, miten voisi vaikuttaa”. Korona: Hus tehohoidon linjajohtaja Minna Bäcklund sanoo olevansa huolissaan rokottamattomien asenteesta. Leikkaukset siirtyvät, kun koronapotilaiden hoito vie paikat. Helsingin Uutiset. 9.10.2021. https://www.helsinginuutiset.fi/paikalliset/4323606

They Had the Vaccines and a Plan to Reopen. Instead They Got Cold Feet. Singapore’s experience offers lessons for other countries that want to reduce pandemic restrictions but have yet to deal with widespread infections. NYT 8.10.2021. https://www.nytimes.com/2021/10/08/world/asia/singapore-vaccine-covid.html

COVID-19 is linked to new diabetes cases—but long-term problems could be more severe.
In addition to driving new cases of diabetes, the virus may be directly damaging the pancreas in ways that could lead to chronic inflammation and even cancer. National Geographic. 8.10.2021. https://www.nationalgeographic.com/science/article/the-many-ways-covid-19-seems-to-be-harming-the-pancreas?

Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study. Lancet. 7.10.2021. https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(21)00383-0/fulltext

Pfizer Asks F.D.A. to Authorize Its Covid-19 Vaccine for Children 5 to 11. The agency has promised to move quickly on the request and tentatively plans to meet on Oct. 26 to consider it. A decision could come soon after Halloween.NYT. 7.10.2021. https://www.nytimes.com/2021/10/07/us/politics/pfizer-fda-authorization-children-5-11.html

SARS-CoV-2 RNA in the Cerebrospinal Fluid of a Patient with Long COVID. SACE Journals. 7.10.2021.  https://journals.sagepub.com/doi/full/10.1177/20499361211048572?fbclid=IwAR1XpHp1_Dabj_NS817YKAAq1lrKzyw5BrfTwNwFfpg6L7ZtDKYjhu-n2Vw&amp;

SARS-CoV-2 emerging variants display enhanced syncytia formation. @IanRicksecker, Also worrisome are syncytia, where an infected cell extrudes its own spike protein and takes over its neighbors, fusing together to create a large multi-nucleus cell.  Delta’s particular aptitude for this may partly explain its severity. NewsMedical. 6.10.2021. https://www.news-medical.net/news/20211006/SARS-CoV-2-emerging-variants-display-enhanced-syncytia-formation.aspx

ECDC:n raportti: Suomi kuuluu maihin, joissa alhainen rokotustaso voi aiheuttaa tartuntojen lisääntymistä ja sairaaloiden kuormittumista. Terveyden ja hyvinvoinnin laitoksen (THL) johtava asiantuntija Mia Kontio kertoo, ettei Suomen jääminen EU- ja ETA-maiden keskiarvon alle ollut yllätys. HS. 6.10.2021. https://www.hs.fi/kotimaa/art-2000008312773.html?share=20625478db85708dd292fc597ff19233

HS muuttaa koronauutisoinnin painopisteen pois tartuntamääristä kohti elämää koronan kanssa. ”Ylhäältä annetun luvan sijasta jokaisen pitää itse päättää, että nyt on turvallista elää enemmän. Korona loppuu siinä vaiheessa, kun kukin meistä itse päättää lakata pelkäämästä”, kirjoittaa HS:n toimituspäällikkö Esa Mäkinen. Helsingin Sanomat. 6.10.2021. https://www.hs.fi/kotimaa/art-2000008243137.html

Kannattaisiko rokotetun nyt altistaa itsensä koronalle? – ”Tätä on mietitty”, toteaa ylilääkäri. Kaksi koronarokoteannosta antaa todennäköisesti hyvän suojan vakavaa tautia vastaan, mutta täydellinen turva se ei ole. Iltalehti. 5.10.2021. https://www.iltalehti.fi/terveysuutiset/a/b9f7d947-af3f-4a5f-812c-f8b7f018cd88

Pääkaupunkiseudulle oma suositus: Käytä maskia julkisissa liikennevälineissä, ihmispaljoudessa ja sairaana. Helsinki, Espoo ja Vantaa luopuvat samalla päiväkotien, koulujen ja oppilaitosten altistumistietojen raportoinnista. YLE-Uutiset. 5.10.2021.  https://yle.fi/uutiset/3-12129425

One-year Risks and Burdens of Incident Cardiovascular Disease in COVID-19: Cardiovascular Manifestations of Long COVID. Research Square. 5.10.2021. https://www.researchsquare.com/article/rs-940278/v1

Koronaepidemia voi poikia syöpärokotteen – ”Näitä ei olisi ikinä muuten syöpätutkimuksessa havaittu”, sanoo Docrateen ylilääkäri. Pfizerin ja Modernan koronarokotteesta tutusta mRNA-tekniikasta haetaan nyt apua vähän kaikkeen, vesikauhusta ja kystisestä fibroosista syöväntorjuntaan. Mediuutiset 4.10.2021. https://www.mediuutiset.fi/uutiset/mu/afa6a794-391d-4005-8081-87aa9d4a5ed2?

THL-johtajan ja pääministerin ulostulot puhuttavat lääkäreitä: ”Viranomaisellakin on jo vähän hätä kädessä”. ”Tämä on marinilainen Suomi: arvoiltaan kova, lapsia, rokottamattomia ja sairaita sortava yhteiskunta. Rokotetuilla vain oikeuksia, ei mitään velvollisuuksia”, ylilääkäri Harri Tohmo kuvailee. Mediuutiset. 4.10.2021. https://www.mediuutiset.fi/uutiset/mu/6709c919-39be-4291-9aab-17f2ea72cf0a?ref=newsletter:d73a

Study confirms SARS-CoV-2 transmission through aerosols, and effectiveness of masks in preventing transmission. MedicalNewsToday. 4.10.2021.

Specific UV light wavelength could offer low-cost, safe way to curb COVID-19 spread. PhysOrg. 4.10.2021. https://phys.org/news/2021-10-specific-uv-wavelength-low-cost-safe.html

Detailed reconstruction of the Iranian COVID-19 epidemic reveals high attack rates of SARS-CoV-2 in several provinces. medRxiv. 4.10.2021. https://www.medrxiv.org/content/10.1101/2021.10.04.21264540v1

Battling Delta, New Zealand Abandons Its Zero-Covid Ambitions. The country is changing course seven weeks into a lockdown that has failed to end the outbreak and tested the patience of many residents. NYT. 4.10.2021. https://www.nytimes.com/2021/10/04/world/australia/new-zealand-covid-zero.html?smid=tw-nytimes&smtyp=cur

Israel Tightens COVID ’Green Pass’ Rules, Sparking Protest. Israel has restricted its COVID Green Pass to allow only those who have received a vaccine booster dose or recently recuperated from coronavirus to enter indoor venues. US News and World Report. 3.10.2021. https://www.usnews.com/news/health-news/articles/2021-10-03/israel-tightens-covid-green-pass-rules-sparking-protest

The 2,000-year-old airborne disease theory that blinded Covid experts
As a result precautions such as wearing masks and better ventilation in public spaces were tragically delayed, says a new report. The Telegraph. 2.10.2021. The 2,000-year-old airborne disease theory that blinded Covid experts (telegraph.co.uk)

Pääministeri Marin kertoo Ylelle, miksi hallitus ohitti THL:n näkemyksen ravintoloista: ”Rokotetuilla on täysi oikeus normaalimpaan elämään”. Sanna Marin myöntää, että ravintoloita koskevien koronarajoitusten reipas lieventäminen voi näkyä tautitapausten kasvuna. Hän ei kuitenkaan pidä koronatilannetta niin huonona, että entisille rajoituksille olisi perusteita. YLE Uutiset. 2.10.2021. https://yle.fi/uutiset/3-12126037

COVID-19 Associated Hepatitis in Children (CAH-C) during the second wave of SARS-CoV-2 infections in Central India: Is it a complication or transient phenomenon. MedRxiv. 2.10.2021. https://www.medrxiv.org/content/10.1101/2021.07.23.21260716v6.full.pdf

Alberta acted like the pandemic was over. Now it’s a cautionary tale for Canada. Saskatchewan faces similar surge in hospitals, while Manitoba is at risk from low vaccination rates. CBC. 2.10.2021. https://www.cbc.ca/news/health/alberta-fourth-wave-surge-hospitals-icu-covid-19-1.6197263

Exhaled particles from nanometre to millimetre and their origin in the human respiratory tract. medRxiv. 1.10.2021. https://www.medrxiv.org/content/10.1101/2021.10.01.21264333v1

The durability of immunity against reinfection by SARS-CoV-2: a comparative evolutionary study. Lancet Microbe. 1.10.2021. https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(21)00219-6/fulltext

Covid-19: Lancet investigation into origin of pandemic shuts down over bias risk. BMJ. 1.10.2021. https://www.bmj.com/content/375/bmj.n2414

U.S. Coronavirus Death Toll Surpasses 700,000 Despite Wide Availability of Vaccines. The latest Covid-19 deaths were concentrated in the South, and included more younger people than before. Every age group under 55 saw its highest death toll of the pandemic this August. NYT. 1.10.2021. https://www.nytimes.com/2021/10/01/us/us-covid-deaths-700k.html

Monitoraggio Fase 2. Report settimanale. Report 72. Sintesi nazionale. ISS. 1.10.2021. https://www.salute.gov.it/imgs/C_17_monitoraggi_81_0_fileNazionale.pdf

Tyksissä jouduttiin perumaan leikkauksia, sillä teholla oli rokottamattomia koronapotilaita. Turun Sanomat. 1.10.2021. https://www.ts.fi/uutiset/5440236

Vaccinating against covid and flu at same time is safe, study shows. BMJ. 1.10.2021. https://www.bmj.com/content/375/bmj.n2411?=&utm

Merck and Ridgeback’s Investigational Oral Antiviral Molnupiravir Reduced the Risk of Hospitalization or Death by Approximately 50 Percent Compared to Placebo for Patients with Mild or Moderate COVID-19 in Positive Interim Analysis of Phase 3 Study. MERCK. 1.10.2021. https://www.merck.com/news/merck-and-ridgebacks-investigational-oral-antiviral-molnupiravir-reduced-the-risk-of-hospitalization-or-death-by-approximately-50-percent-compared-to-placebo-for-patients-with-mild-or-moderat/

SARS-CoV-2 infections elicit higher levels of original antigenic sin antibodies compared to SARS-CoV-2 mRNA vaccinations. MedRxiv. 1.10.2021.  https://www.medrxiv.org/content/10.1101/2021.09.30.21264363v1

In Portugal, There Is Virtually No One Left to Vaccinate. Portugal is among the most highly vaccinated countries in the world. Vice Adm. Henrique Gouveia e Melo, who led the campaign, said there was a key to his success: Keep politics out of it. NYT. 1.10.2021. https://www.nytimes.com/2021/10/01/world/europe/portugal-vaccination-rate.html

October 1-10

Reliability of COVID- 19 symptom checkers as national triage tools: an international case comparison study. BMJ. 30.9.2021. extension://elhekieabhbkpmcefcoobjddigjcaadp/https://informatics.bmj.com/content/bmjhci/28/1/e100448.full.pdf

COVID-19 Tutkimuskatsaus 11/2021. Koronakriisiin liittyviä ajankohtaisia tutkimustuloksia maailmalta ja Suomesta. Valtioneuvosto. 30.9.2021. https://julkaisut.valtioneuvosto.fi/bitstream/handle/10024/163530/COVID-19-tutkimuskatsaus%2011-2021.pdf?sequence=1&isAllowed=y

What are the long-term effects of COVID-19?
What we know
Mild and moderate cases
Severe cases
Mental health
Treatment and support
Chronic fatigue syndrome
When to seek help
Summary
Most people who develop coronavirus disease 19 (COVID-19) recover within 2–6 weeks, but some experience lasting symptoms. Others with severe COVID-19 may develop complications, require rehabilitation after a hospital stay, or both. Medical News Today. 29.9.2021.  https://www.medicalnewstoday.com/articles/long-term-effects-of-coronavirus?utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=MNT%20Daily%20News&utm_content=2021-11-06&apid=32395010&rvid=348b31007bc4905a3c503d64d5572c0dac87e7263eba83389e708a2774ce1afc

DNA vs. mRNA vaccines: Similarities and differences
DNA and RNA vaccines use genetic material to deliver information to human cells and elicit an immune response. DNA vaccines are safe, easy, affordable to produce, and, unlike RNA vaccines, are stable at room temperature. These attributes make them more promising for rapidly immunizing populations, especially in resource-limited settings. Medical News Today. 28.9.2021.  https://www.medicalnewstoday.com/articles/dna-vs-mrna-vaccines-similarities-and-differences?utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=MNT%20Daily%20News&utm_content=2021-11-06&apid=32395010&rvid=348b31007bc4905a3c503d64d5572c0dac87e7263eba83389e708a2774ce1afc

Evolving phenotypes of non-hospitalized patients that indicate long COVID. BMC Medicine. 27.9.2021. https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-021-02115-0

Yhdysvaltalaistutkimus: Näin koulujen maski­pakko suojasi lapsia korona­virukselta. Yhdysvaltain tautikeskus CDC julkaisi perjantaina kaksi tutkimusta, jotka käsittelevät maskien käyttöä kouluissa. IS. 25.9.2021.  https://www.is.fi/ulkomaat/art-2000008288977.html

U.S. schools with mask requirements are seeing fewer outbreaks, the C.D.C. finds. NYT. 24.9.2021. https://www.nytimes.com/2021/09/24/health/schools-mask-mandate-outbreaks-cdc.html?smtyp=cur&smid=fb-nytimes

Association Between K-12 School Mask Policies and School-Associated COVID-19 Outbreaks – Maricopa and Pima Counties, Arizona, June-August 2021. CDC. Morbidity and Mortality Weekly Report (MMWR). 24.9.2021. https://www.cdc.gov/mmwr/volumes/70/wr/mm7039e1.htm

Pediatric COVID-19 Cases in Counties With and Without School Mask
Requirements — United States, July 1–September 4, 2021. CDC. Morbidity and Mortality Weekly Report (MMWR). 24.9.2021. https://www.cdc.gov/mmwr/volumes/70/wr/mm7039e3.htm

New ease of measures announced: The new rules were announced on 23 September by the Prime Minister, António Costa, at the end of the Ministers meeting in which it was decided that Portugal will enter in the third and last phase of the ease of lockdown plan approved on 29 July. Find out everything you need to know about the new measures. The Portugal News. 23.9.2021. https://www.theportugalnews.com/news/2021-09-23/new-ease-of-measures-announced/62580

Epidemia COVID-19. Aggiornamento nazionale 22 settembre 2021 – ore 12:00. ISS. 24.9.2021. https://www.epicentro.iss.it/coronavirus/bollettino/Bollettino-sorveglianza-integrata-COVID-19_22-settembre-2021.pdf

SARS-CoV-2 infection causes immunodeficiency in recovered patients by downregulating CD19 expression in B cells via enhancing B-cell metabolism. Nature. 22.9.2021. https://www.nature.com/articles/s41392-021-00749-3

New Zealand growth in Q2 2021 confirms the Zero-Covid strategy outperforms the mitigation strategy of the G10 countries: 44 times less deaths, pre-crisis GDP exceeded, mobility and daily freedoms better preserved. Institut Economique Molinari. 21.9.2021.  https://www.institutmolinari.org/2021/09/21/new-zealand-growth-in-q2-2021-confirms-the-zero-covid-strategy-outperforms-the-mitigation-strategy-of-the-g10-countries-44-times-less-deaths-pre-crisis-gdp-exceeded-mobility-and-daily-freedoms-bett/

 

September 21-30

Coronaviruses with a SARS-CoV-2-like receptor-binding domain allowing ACE2-mediated entry into human cells isolated from bats of Indochinese peninsula. ResearchSquare. 17.9.2021. https://www.researchsquare.com/article/rs-871965/v1

Muistio paljastaa: Näin THL ja STM kävivät kiistaa Suomen hybridi­strategiasta. THL toi muistiossa esille huolensa siitä, onko STM arvioinut muuttuneessa tilanteessa riittävästi erilaisten rajoitustoimien oikeasuhtaisuutta ja välttämättömyyttä. Ilta=Sanomat. 16.9.2022. https://www.is.fi/politiikka/art-2000008267749.html

Post-COVID Conditions. CDC.16.9.2021. https://www.cdc.gov/coronavirus/2019-ncov/long-term-effects/index.html

EXCLUSIVE WHO-backed vaccine hub for Africa to copy Moderna COVID-19 shot. Reuters. 15.9.2021. https://www.reuters.com/world/africa/exclusive-who-backed-vaccine-hub-africa-copy-moderna-covid-19-shot-2021-09-14/

Successful control of COVID-19 outbreak through tracing, testing, and isolation: Lessons learned from the outbreak control efforts made in a metropolitan city of South Korea. Journal of Infection and Public Health. nn.9.2021. https://www.sciencedirect.com/science/article/pii/S1876034121001908

Why are Covid vaccine boosters needed and who in the UK will receive them?
Britain is joining nine other countries that have announced similar programmes offering an additional jab. FT. 14.9.2021. https://www.ft.com/content/cf83b3a1-fe06-4c9f-999c-7500090aee7c

11% of Israeli kids who got virus now suffer from ‘long COVID’ – study. Health Ministry survey finds 30% of those with long-term effects have cognitive, mental health issues, but cautions these can also be attributed to lockdowns, school closures, war. The Times of Israel. 14.9.2021.  https://www.timesofisrael.com/more-than-10-of-israeli-kids-who-got-virus-now-suffer-from-long-covid-study/

Covid-19 and the new merchants of doubt. How best can scientists push back against science denialist campaigns? David Gorski and Gavin Yamey suggest some evidence based strategies. BMJ. 13.9.2021. https://blogs.bmj.com/bmj/2021/09/13/covid-19-and-the-new-merchants-of-doubt/

Genetic emergence of B.1.617.2 in COVID-19. New Microbes and New Infections NN.9.2021. https://www.sciencedirect.com/science/article/pii/S2052297521000937

September 11-20

 

Kommentti: Kuka jatkossa saa hoitoa? STM:n tuleva kansliapäällikkö sanoi sen, mitä muut eivät uskalla. Kirsi Varhila ansaitsee kiitosta rohkeudestaan. Hän nosti esiin asian, joka on poliittisesti tulenarka ja siksi siitä ollaan hiljaa, kirjoittaa erikoistoimittaja Heidi Hagelin. IS. 10.9.2021. https://www.is.fi/kotimaa/art-2000006234237.html

Keskustelun koronatesteistä tulee perustua tutkimusnäyttöön
Pikatestit löytävät koronavirusta tartuttavat yksilöt paremmin kuin Suomessa on ymmärretty. Kuka tartutti kenet -strategiasta voitaisiin siirtyä tartuntojen ennaltaehkäisyyn. Lääkärilehti. 8.9.2021. https://www.laakarilehti.fi/ajassa/verkkokommentti/keskustelun-koronatesteista-tulee-perustua-tutkimusnayttoon/?

Dose-dependent COVID-19 symptoms. (COVID-19 presentation varies widely between individuals, ranging from asymptomatic to life-threatening infection. Several host and viral factors have been shown to influence disease penetrance and severity. In addition, the infectious dose has also been speculated to have a role. Dabisch et al. show in a SARS-CoV-2 challenge study of 16 cynomolgus macaques that the infectious dose indeed influences symptom development and seroconversion. They used aerosolized virus at different concentrations and found that low doses could lead to seroconversion and virus replication in the respiratory tract without symptom development, such as fever, whereas higher doses produced fever, which suggest that low infectious doses might be associated with asymptomatic infection.)nature reviews microbiology. 7.9.2021. https://www.nature.com/articles/s41579-021-00634-4

Toimintasuunnitelma COVID-19 -epidemian hillinnän hybridistrategian toteuttamiseksi 2021-22. Luonnos 6.9.2021. VNK. https://vnk.fi/documents/10616/25232448/Hybridistrategian+toimintasuunnitelma+4.0.+luonnos+6.9.2021.pdf/446884d4-13d4-68c4-fa25-9b684940aa04/Hybridistrategian+toimintasuunnitelma+4.0.+luonnos+6.9.2021.pdf?t=1630944929454

THL:n Salminen: Pandemian loppusuora häämöttää – paluuta koviin rajoituksiin tuskin tullaan näkemään. THL:n Mika Salmisen mukaan rokotekattavuus on nyt tärkein epidemiatilanteesta kertova mittari, ja päivittäisten koronalukujen raportoinnista voitaisiin jo luopua. Paluu normaaliin häämöttää jo, sillä ensi viikolla Suomeen on tullut riittävästi rokotteita 80 prosentin rokotekattavuuden saavuttamiseksi. YLE. 5.9.2021.  https://yle.fi/uutiset/3-12085688

Total Anti-SARS-CoV-2 Antibodies Measured 6 Months After Pfizer-BioNTech COVID-19 Vaccination in Healthcare Workers.  SSRN. 3.9.2021. https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3915349

Downsides of face masks and possible mitigation strategies: a systematic review and meta-analysis. BMJ Open. 2.9.2022. https://bmjopen.bmj.com/content/11/2/e044364.info

On the effect of COVID-19 pandemic in the excess of human mortality. The case of Brazil and Spain. PLOS One. 2.9.2021. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0255909

Has Covid ended the neoliberal era? The year 2020 exposed the risks and weaknesses of the market-driven global system like never before. It’s hard to avoid the sense that a turning point has been reached. Guardian. 2.9.2021. https://www.theguardian.com/news/2021/sep/02/covid-and-the-crisis-of-neoliberalism

Risk factors and disease profile of post-vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: a prospective, community-based, nested, case-control study. @IanRicksecker … finding contradicts the findings from the UK Zoe app study, which found that “the odds of having symptoms for 28 days or more after post-vaccination infection were approximately halved by having two vaccine doses.” LANCET Infectious Diseases. 1.9.2021. https://doi.org/10.1016/S1473-3099(21)00460-6

September 1-10

Airborne transmission of respiratory viruses. Science . 27.8.2021. https://doi.org/10.1126/science.abd9149

SARS-CoV-2 infection of the central nervous system in a 14-month-old child: A case report of a complete autopsy. @IanRicksecker, An autopsy of a 14-month-old at Brazil’s Federal University of Rio de Janeiro found that “The brain exhibited severe atrophy and neuronal loss.” Lancet Regional Health Americas. 27.8.2021. https://doi.org/10.1016/j.lana.2021.100046

When it comes to staff safety during the pandemic, the buck stops with chief executives. One of the main preventive roles of occupational health experts in the pandemic is, or should have been, to advise and support managers/employers in risk management and control both as regards compliance with legal duties on health and safety. HSJ Wilmington Healthcare. 24.8.2021. https://www.hsj.co.uk/policy-and-regulation/when-it-comes-to-staff-safety-during-the-pandemic-the-buck-stops-with-chief-executives/7030773.article

Using test positivity and reported case rates to estimate state-level COVID-19 prevalence
and seroprevalence in the United States. PLOS Comp Biol. 23.8.2021.  https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1009374&type=printable

Seroconversion and fever are dose-dependent in a nonhuman primate model of inhalational COVID-19. PLOS Pathogens. 23.8.2021.  https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1009865

A microscopic video shows the coronavirus on the rampage. @IanRicksecker, And, yes, syncytia formation can happen in neurons. For our visual learners, here is video of syncytia and apoptosis (cell death) in a (bat) brain: NYT. 22.8.2021. https://www.nytimes.com/2021/08/22/science/microscopic-bat-brain-virus.html?smid=tw-nytimes&smtyp=cur

Persistent clotting protein pathology in Long COVID/Post-Acute Sequelae of COVID-19 (PASC) is accompanied by increased levels of antiplasmin. Cardiovascular Diabetology. 23.8.2021. https://cardiab.biomedcentral.com/articles/10.1186/s12933-021-01359-7

COVID-19-associated hyperinflammation and escalation of patient care: a retrospective longitudinal cohort study. Lancet. 21.8.2021 https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(20)30275-7/fulltext

August 21 – 31

Perspective. The Covid-19 Infodemic — Applying the Epidemiologic Model to Counter Misinformation. NEJM. 19.8.2021. https://www.nejm.org/doi/full/10.1056/NEJMp2103798

Similar patterns of [18F]-FDG brain PET hypometabolism in paediatric and adult patients with long COVID: a paediatric case series. European Journal of Nuclear Medicine and Molecular Imaging. 19.8.2021. https://link.springer.com/article/10.1007/s00259-021-05528-4

Brain imaging before and after COVID-19 in UK Biobank. @IanRicksecker, The UK Biobank COVID-19 re-imaging study compared before and after images of “mild” cases, and found “pronounced reduction in grey matter” and an “increase of diffusion indices, a marker of tissue damage” in specific regions of the brain. medRxiv. 18.8.2021. https://doi.org/10.1101/2021.06.11.21258690

Japan extends COVID-19 emergency lockdown as cases surge. Reuters. 18.8.2021. https://www.reuters.com/world/asia-pacific/japan-set-extend-covid-19-state-emergency-lockdown-sept-12-2021-08-17/

How COVID-19 vaccine supply chains emerged in the midst of a pandemic. PIIE. nn.8.2021. https://www.piie.com/publications/working-papers/how-covid-19-vaccine-supply-chains-emerged-midst-pandemic?

Infectious SARS-CoV-2 in Exhaled Aerosols and Efficacy of Masks During Early Mild Infection. medRxiv. 13.8.2021. https://www.medrxiv.org/content/10.1101/2021.08.13.21261989v1.full.pdf

The Vaccine Scientist Spreading Vaccine Misinformation. Robert Malone claims to have invented mRNA technology. Why is he trying so hard to undermine its use? Atlantic. 12.8.2021. https://www.theatlantic.com/science/archive/2021/08/robert-malone-vaccine-inventor-vaccine-skeptic/619734/

Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant. NEJM. 12.8.2021. https://www.nejm.org/doi/full/10.1056/NEJMoa2108891

A molecular test based on RT-LAMP for rapid, sensitive and inexpensive colorimetric detection of SARS-CoV-2 in clinical samples. Scientific Reports. 12.8.2021. https://www.nature.com/articles/s41598-021-95799-6

Impact of the COVID-19 Pandemic on Early Child Cognitive Development: Initial Findings in a Longitudinal Observational Study of Child Healt. medRxiv. 11.8.2021. https://www.medrxiv.org/content/10.1101/2021.08.10.21261846v1.full.pdf

Persistent Exertional Intolerance After COVID-19. Insights From Invasive Cardiopulmonary Exercise Testing. @IanRicksecker These patients are struggling with real physical issues. This Yale study demonstrated reduced aerobic capacity, oxygen extraction. and ventilatory efficiency in “mild” COVID patients even after recovery from their acute infection. CHEST Journal. 10.8.2021. https://doi.org/10.1016/j.chest.2021.08.010

August 11 – 20

We Studied One Million Students. This Is What We Learned About Masking. New York Times. 10.8.2021. https://www.nytimes.com/2021/08/10/opinion/covid-schools-masks.html

Moderna may be superior to Pfizer against Delta; breakthrough odds rise with time. Reuters. 9.8.2021. https://www.reuters.com/business/healthcare-pharmaceuticals/moderna-may-be-superior-pfizer-against-delta-breakthrough-odds-rise-with-time-2021-08-09/

More than 50 long-term effects of COVID-19: a systematic review and meta-analysis. Scientific Reports. 9.8.2021. https://www.nature.com/articles/s41598-021-95565-8

KOTIMAA: Laumasuojateoria romahti, Suomessa suhde maskeihin mullistui yhdessä kesässä – näin tieto koronasta on muuttunut . Kiinan Wuhanista vuoden 2019 lopulla levinneeseen virukseen on liitetty useita harhaluuloja. Ilta=sanomat. 8.8.2021. https://www.is.fi/kotimaa/art-2000008179086.html

Viral infection and transmission in a large well-traced outbreak caused by the Delta SARS-CoV-2 variant. 7.8.2021. https://virological.org/t/viral-infection-and-transmission-in-a-large-well-traced-outbreak-caused-by-the-delta-sars-cov-2-variant/724

Pediatricians plead with FDA to move quickly on Covid vaccine for kids
”The delta variant has created a new and pressing risk to children and adolescents across this country,” president of the leading pediatricians group wrote. NBC News. 7.8.2021. https://www.nbcnews.com/health/health-news/pediatricians-plead-fda-move-quickly-covid-vaccine-kids-n1276191

The Pandemic Will End The Only Way It Can — The Hard Way. We still haven’t learned. Medium. 7.8.2021. https://jessicalexicus.medium.com/the-pandemic-will-end-the-only-way-it-can-the-hard-way-9770f003da9

Viral Load of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Respiratory Aerosols Emitted by Patients With Coronavirus Disease 2019 (COVID-19) While Breathing, Talking, and Singing. Clinical Infectious Diseases. 6.8.2021. https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciab691/6343417

Worauf warten Sie noch? Das ausgebuchte Impfzentrum ist keine Ausrede mehr – Ihre Hausärztin müsste längst Impfstoff für Sie haben. Zehn Gründe, mit der Corona-Impfung nicht länger zu warten. Zeit OnLine. 5.8.2021.  https://www.zeit.de/gesundheit/2021-08/corona-impfung-nebenwirkungen-delta-variante-zweitimpfung-wirksam

Prevalence of ongoing symptoms following coronavirus (COVID-19) infection in the UK: 1 July 2021. ONS. 5.8.2021. https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/prevalenceofongoingsymptomsfollowingcoronaviruscovid19infectionintheuk/1july2021

Reduced neutralization of SARS-CoV-2 B.1.617 by vaccine and convalescent serum. Cell. 5.8.2021. https://www.sciencedirect.com/science/article/pii/S0092867421007558

Post-acute sequelae of COVID-19 in a non-hospitalized cohort: Results from the Arizona CoVHORT. @IanRicksecker The CoVHORT study, limited to non-hospitalized patients in Arizona – “mild” cases – found a 68% prevalence of 1 or more Covid symptom after 30 days, rising to 77% after 60 days. PLOS ONE. 4.8.2021.  https://doi.org/10.1371/journal.pone.0254347

Where will you need a covid passport? Proof of vaccination or recovery from infection is increasingly being demanded, not just for international travel but also within countries. Economist. 4.8.2021. https://www.economist.com/the-economist-explains/2021/08/04/where-will-you-need-a-covid-passport

Asiantuntija penää selkeää linjaa: Mikä on ”riittävä rokotekattavuus” ja ”hyväksyttävä määrä” tartuntoja? Virustutkija Tuomas Aivelon mukaan kukaan ei tunnu tietävän, millainen rokotekattavuus olisi riittävä. Iltalehti. 4.8.2021. https://www.iltalehti.fi/koronavirus/a/098c101b-3a8d-467e-929e-5b590d0d7a13

Wuhan back in spotlight as China’s Delta variant challenge grows
China reports 328 locally transmitted cases in July — equal to previous five months’ total. AA. 3.8.2021. https://www.aa.com.tr/en/asia-pacific/wuhan-back-in-spotlight-as-chinas-delta-variant-challenge-grows/2322769

The association of opening K–12 schools with the spread of COVID-19 in the United States: County-level panel data analysis. PNAS. 3.8.2021. https://www.pnas.org/content/118/42/e2103420118

THL:n Mika Salmisen arvio: Tällainen on Suomen uusi koronastrategia. Suomen uusi koronastrategia saattaa muistuttaa aiemmin käytössä ollutta hybridimallia, mutta luvassa on myös merkittäviä muutoksia aiempaan. Ilta=sanomat. 3.8.2021. https://www.is.fi/kotimaa/art-2000008165493.html

Lapsi­asia­valtuutettu vaatii kouluihin muutoksia koronan takia: ”Herkästi tarttuvat virus­muunnokset herättävät pelkoa”. Moitteita saa myös muun muassa lapsille ja nuorille suunnattu viestintä. Ilta=sanomat. 3.8.2021. https://www.is.fi/kotimaa/art-2000008167789.html

Kainuun sote testasi 74 ulkomaalaisen marjanpoimijan ryhmän: tartuntoja löytyi 44
Ulkomaalaisten marjanpoimijoiden ryhmässä 44 koronatartuntaa Kainuussa. Iltalehti. 3.8.2021. https://www.iltalehti.fi/kotimaa/a/93b675fe-7cf4-4274-9123-e3dbf4b51f29

Text-message nudges encourage COVID vaccination. A field trial shows that text-message ‘nudges’ encourage people to get vaccinated against COVID-19. To be effective, nudge approaches such as this must combine three aspects: they must prompt, enable and motivate behaviour. Nature. 2.8.2021. https://www.nature.com/articles/d41586-021-02043-2

Delta infections among vaccinated likely contagious; Lambda variant shows vaccine resistance in lab. Reuters. 2.8.2021. https://www.reuters.com/business/healthcare-pharmaceuticals/delta-infections-among-vaccinated-likely-contagious-lambda-variant-shows-vaccine-2021-08-02/

Suojaako jo yksi rokote pitkittyneeltä koronalta? Asiantuntijat vastaavat. Long covidin eli pitkittyneen koronan mahdollisuus mietityttää monia. Asiantuntijat kertovat, mitä nyt tiedetään rokotteiden tehosta sitä vastaan. Iltalehti. 2.8.2021. https://www.iltalehti.fi/terveysuutiset/a/b1367256-1f2f-4339-b722-7f45ec57ebb8

Microbiologist Elisabeth Bik queried Covid research – that’s when the abuse and trolling began. Bik’s home address was posted on Twitter and she faced a barrage of attacks after dissecting a paper endorsing hydroxychloroquine as treatment. Guardian. 2.8.2021. https://www.theguardian.com/science/2021/aug/03/microbiologist-elisabeth-bik-queried-covid-research-thats-when-the-abuse-and-trolling-began?CMP=Share_iOSApp_Other

Lääkärit huolissaan koulujen alkamisen riskeistä: ”Oppivelvollisten sairastuttaminen olisi vastuutonta ja typerää”. Uusi Suomi. 1.8.2021. https://www.uusisuomi.fi/uutiset/laakarit-huolissaan-koulujen-alkamisen-riskeista-oppivelvollisten-sairastuttaminen-olisi-vastuutonta-ja-typeraa/f79f22cc-4e0e-4233-b504-e31130247c8b

Brittiasiantuntijat varoittavat: Englannin puolittuneet koronatartunnat eivät välttämättä kerro todellisesta tilanteesta – tässä syy. mtv-uutiset. 1.8.2021. https://www.mtvuutiset.fi/artikkeli/brittiasiantuntijat-varoittavat-englannin-puolittuneet-koronatartunnat-eivat-valttamatta-kerro-todellisesta-tilanteesta-tassa-syy/8202752

Florida, COVID-19 epicentre in the U.S., breaks record with more than 21,000 new cases.
Sunshine State accounts for about a fifth of all new coronavirus cases in the country. CBC News. 1.8.2021. https://www.cbc.ca/news/world/florida-daily-cases-covid19-1.6125757

Nyssessä ei toistaiseksi oteta maskipakkoa uudestaan käyttöön – poistettiin juuri ennen kuin tartuntatapaukset alkoivat jyrkästi nousta: ”Ajoitus ei ollut täydellinen”
Maskipakkoa ei oteta uudestaan käyttöön, koska sen teho ei olisi enää yhtä suuri kuin aiemmin. Aamulehti. 1.8.2021. https://www.aamulehti.fi/koronavirus/art-2000008164627.html

Mask Mandates Save Lives. IMF Working Paper WP/21/205 nn.8.2021https://www.elibrary.imf.org/downloadpdf/journals/001/2021/205/001.2021.issue-205-en.pdf

What is the newly found COVID-19 ’Epsilon variant’ in Pakistan? – Details inside
New Epsilon variant found in Pakistan in its fourth wave amid the surge of COVID-19 cases.DNA India. 2.8.2021. https://www.dnaindia.com/science/report-what-is-the-newly-found-covid19-epsilon-variant-in-pakistan-details-inside-covid19-new-variant-coronavirus-new-variant-epsilon-variant-pakistan-lahore-california-4th-wave-coronavirus-news-alerts-latest-updates-2903645

In Provincetown 14 friends nab covid in a show of Delta’s might. Bloomberg. 1.8.2021. https://www.bloomberg.com/news/articles/2021-08-01/in-provincetown-14-friends-nab-covid-in-show-of-delta-s-might

Miten Suomi päätti voittaa koronan. Adlibris. 1.8.2021. https://www.adlibris.com/fi/kirja/miten-suomi-paatti-voittaa-koronan-9789523515178

August 1-10

Miksi korona ei ryöpsähdä Afrikassa? Viisi koronamysteeriä, jotka ovat vailla vastauksia
Tartuntatautien tutkimuskeskuksen johtajan mukaan virus ei ole levinnyt odotetusti. ILtalehti. 31.7.2021. https://www.iltalehti.fi/ulkomaat/a/21ac0b79-08d7-49a1-a76b-c9879e8053fd

Porilaistaustainen erikoislääkäri Maria Juusela pitää ministereiden lähikoulupuhetta edesvastuuttomana – lapset etäkouluun ja kaikki rokotuksiin: ”Kuka ottaa vastuun, jos vanhempi kieltää lapselta koronarokotteen ja tämä sairastuu vakavasti?
Keuhkosairauksiin erikoistunut erikoislääkäri Maria Juusela varoittaa koronarokotusten viivyttelystä, sillä nuorten ja rokottamattomien osuus sairaalahoidossa kasvaa. Nuoria on jo nyt tehohoidossa ja puolet lievänkin koronan saaneista nuorista kärsii tutkimusten mukaan long covid -oireista. Satakunnan Kansa. 31.7.2021. https://www.satakunnankansa.fi/satakunta/art-2000008157559.html

Yli 20 uutta tartuntaa rippileirillä levinneestä koronaryppäästä – altistuneiden määrää lähes mahdoton arvioida. Koronavirus ehti levitä rippileirillä tehokkaasti. Lääkäri epäilee, että lähes kaikki leirille osallistuneet ovat voineet sairastua. YLE-Uutiset. 31.7.2021. https://yle.fi/uutiset/3-12042355

”FFP2-suojain on ainoa tapa, jolla omaa turvallisuuttaan voi parantaa” – Deltavariantti leviää helposti myös ulkona, asian­tuntija kertoo, miten se on syytä huomioida
Deltavariantti tarttuu aiempia variantteja herkemmin myös ulkotiloissa. Asiantuntija neuvoo hyödyntämään tupakansavu­sääntöä ja käyttämään maskia, jos etäisyyttä ei voi pitää. Helsingin Sanomat. 31.7.2021. https://www.hs.fi/hyvinvointi/art-2000008161774.html

Evidence of lung perfusion defects and ongoing inflammation in an adolescent with post-acute sequelae of SARS-CoV-2 infection. Lancet. 30.7.2021. https://www.thelancet.com/pdfs/journals/lanchi/PIIS2352-4642(21)00196-6.pdf

CDC document warns Delta variant appears to spread as easily as chickenpox and cause more severe infection. CNN Politics. 30.7.2021. https://edition.cnn.com/2021/07/29/politics/cdc-masks-covid-19-infections/index.html

Vaccinated People May Spread the Virus, Though Rarely, C.D.C. Reports
The agency cited an outbreak in Provincetown, Mass., in which most of the infected were immunized. An internal C.D.C. document paints an even more harrowing picture. New York Times. 30.7.2021. https://www.nytimes.com/2021/07/30/health/cdc-vaccinated-delta.html

FFP3 masks: study shows they significantly reduce the risk of COVID-19 infection. Royal College of Nursing. 29.7.2021. https://www.rcn.org.uk/news-and-events/news/uk-ffp3-masks-study-shows-they-significantly-reduce-the-risk-of-covid-19-infection-290621

COVID-19 ASSOCIATED WITH LONG-TERM COGNITIVE DYSFUNCTION, ACCELERATION OF ALZHEIMER’S SYMPTOMS. AAIC 21. 29.7.2021. https://www.alz.org/aaic/downloads2021/COVID-19_and_Long-Term_Cognitive_Dysfunction.pdf

Covid-19 linked to cognitive decline, acceleration of Alzheimer’s-like symptoms, research finds. CNN Heakth. 29.7.2021. https://edition.cnn.com/2021/07/29/health/covid-cognitive-decline-alzheimers/index.html

An outbreak caused by the SARS-CoV-2 Delta variant (B.1.617.2) in a secondary care hospital in Finland, May 2021. Eurosurveilance. 29.7.2021. https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2021.26.30.2100636

A look into the future of the COVID-19 pandemic in Europe: an expert consultation. Lancet Regional Health for Europe. 29.7.2021. https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(21)00162-9/fulltext

New study finds COVID-19 can cause changes in brain that mimic Alzheimer’s disease. FOX9. 29.7.2021. https://web.archive.org/web/20210730041354/https://www.fox9.com/news/new-study-finds-covid-19-can-cause-changes-in-brain-that-mimics-alzheimers-disease

SARS-CoV-2 Lambda variant exhibits higher infectivity and immune resistance. bioRxiv. 28.7.2021. https://www.biorxiv.org/content/10.1101/2021.07.28.454085v1

Israeli hospitals reopen their coronavirus wards as serious cases mount
Number of serious patients reaches 153, having more than doubled in a week, Health Ministry data shows. The Times of Israel. 28.7.2021. https://www.timesofisrael.com/israeli-hospitals-reopen-their-coronavirus-wards-as-serious-cases-mount/

Texas doctor warns COVID-19 cases are rising among children. Some are on ventilators. The Hill. 28.7.2021. https://thehill.com/changing-america/well-being/longevity/565323-texas-doctor-warns-covid-cases-are-rising-among

Hoitoalalla työskentelevä nainen järkyttyi Tikkurila Festivaalilla – Turvaväleistä ei puhettakaan, maskeja ei yleisössä kellään. Vantaan Sanomat. 27.7.2021. https://www.vantaansanomat.fi/paikalliset/4235633

COVID-19 false dichotomies and a comprehensive review of the evidence regarding public health, COVID-19 symptomatology, SARS-CoV-2 transmission, mask wearing, and reinfection. @IanRicksecker It’s even good for the economy: ”Globally, economic contraction and growth closely mirror increases and decreases in COVID-19 cases… Public health strategies that reduce SARS-CoV-2 transmission also safeguard the economy.” BMC Infectious Diseases. 27.7.2021. https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-021-06357-4

COVID-19-infektioon liittyvä lasten hyperinflammatorinen oireyhtymä. Duodecim. 27.7.2021. https://www.duodecimlehti.fi/duo15880

UPDATE week to 26-July. Childhood COVID, England. @jneill. 26.7.2021. https://twitter.com/jneill/status/1419697733632471047?s=12

Long COVID cases among children and pediatric death toll rise globally. World Socialist Web Site. 26.7.2021. https://www.wsws.org/en/articles/2021/07/27/long-j27.html

Biden says ’long COVID’ patients could qualify for having disability. UPI. 26.10.2021. https://www.upi.com/Top_News/US/2021/07/26/bs-us-long-covid-disability-biden/1031627316110/

Doctors Worry That Memory Problems After COVID-19 May Set The Stage For Alzheimer’s. NPR. 26.7.2021. https://www.npr.org/sections/health-shots/2021/07/26/1019875347/doctors-worry-that-memory-problems-after-covid-19-may-set-stage-for-alzheimers?t=1644221638372

COVID-19 linked to ’substantial’ drop in intelligence, new research finds
People who had been hospitalised and put on a ventilator saw the biggest deficit in the Great British Intelligence Test – equivalent to a seven-point drop in IQ. Sky news. (Long COVID)  26.7.2021. https://news.sky.com/story/covid-19-linked-to-substantial-drop-in-intelligence-new-research-finds-12364433

The mystery of COVID-19 reinfections: A global systematic review and meta-analysis of 577 cases. medRxiv. 25.7.2021. https://www.medrxiv.org/content/10.1101/2021.07.22.21260972v2.full.pdf

Falling off the cliff: Mythical sacrifice mirrored in Sweden’s COVID-19 response. AAGE. 23.7.2021. http://anthropologyandgerontology.com/falling-off-the-cliff-mythical-sacrifice-mirrored-in-swedens-covid-19-response/

SARS-COV-2 Delta variant now dominant in much of the European Region and efforts must be reinforced to prevent transmission, warn WHO/Europe and ECDC. ECDC. 23.7.2021. https://www.ecdc.europa.eu/en/news-events/sars-cov-2-delta-variant-now-dominant-european-region

Cognitive deficits in people who have recovered from COVID-19. @IanRicksecker, That seems to explain why there is evidence of persistent cognitive deficits in people who have recovered from SARS-CoV2 infection in Great Britain. EClinicakMedicine. 22.7.2021.  https://doi.org/10.1016/j.eclinm.2021.101044

Short Report on Long COVID. This report is provided at the request of SAGE and includes information from ongoing studies investigating long COVID including the COVID-19 Longitudinal Health and Wellbeing National Core. Study-CONVALESCENCE Study, REACT-2, PHOSP-COVID, ONS’s COVID-19 Infection Survey (CIS) and the COVID Symptom Study App. ONS. 22.7.2021. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1007511/S1327_Short_Long_COVID_report.pdf

Hospital length of stay for COVID-19 patients: Data-driven methods for forward planning. BMC Infectious Diseases. 22.7.2022. https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-021-06371-6

We’re Zeroing In On the ‘Holy Grail’ of COVID-19 Immunity. There’s no good way of measuring whether your vaccine worked—yet. Atlantic. 21.7.2021.  https://www.theatlantic.com/science/archive/2021/07/correlates-of-protection-vaccine-immunity/619508/

CDC 2019-Novel Coronavirus (2019-nCoV) Real-Time RT-PCR Diagnostic Panel For Emergency Use Only:Instructions for Use. 21.7.2021. https://www.fda.gov/media/134922/download

Cognitive deficits in people who have recovered from COVID-19. Lancet. 21.7.2021. https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(21)00324-2/fulltext

July 21 – 31

FFP3 masks: study shows they significantly reduce the risk of COVID-19 infection. Royal College of Nursing. 29.7.2022. https://www.rcn.org.uk/news-and-events/news/uk-ffp3-masks-study-shows-they-significantly-reduce-the-risk-of-covid-19-infection-290621

Covid: ’Beware Of Epsilon Variant, Risk Of Infection Even For Immunised People’. Epsilon variant of Covid: only two cases, in Italy, already isolated. Emergency LIVE. 19.7.2021. https://www.emergency-live.com/news/covid-beware-of-epsilon-variant-risk-of-infection-even-for-immunised-people/

’Acute Covid’ spreading in young people can ’rip through their organs’, expert warns
Professor Calum Semple has warned that while they may not be at risk of death, young people could be ”damaged” by the devastating effects of acute Covid on their organs. Mirror. 15.7.2021. https://www.mirror.co.uk/news/uk-news/acute-covid-spreading-young-people-24539633?

Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents. JAMA Network. 15.8.2021. https://jamanetwork.com/journals/jama/fullarticle/2782164

Air pollution, racial disparities, and COVID-19 mortality. Journal of Allergy and Clinical Immunology. NN.7.2021. https://www.sciencedirect.com/science/article/pii/S0091674920306321

Presence of SARS-CoV-2 Aerosol in Residences of Adults with COVID-19. Annals of American Thoracic Society. nn.7.2021. https://www.atsjournals.org/doi/full/10.1513/AnnalsATS.202107-847RL

Kaikkien koronatartuntojen estäminen rajoituksilla on mahdotonta, sanoo THL:n Hanna Nohynek: ”Olemme kohta kuin Pohjois-Koreassa”
Emeritusprofessori Matti Jantunen on toista mieltä: hänestä rajoitusten purku olisi kuin sallisi humalassa ajamisen. Yhteiskunnan avaamisen aikataulu on arvokysymys. Suomen Kuvalehti. 14.7.2022. https://suomenkuvalehti.fi/kotimaa/kaikkien-koronatartuntojen-estaminen-rajoituksilla-on-mahdotonta-sanoo-thln-hanna-nohynek-olemme-kohta-kuin-pohjois-koreassa/

THL:n Salminen: ”Elämä palaa vanhoille raiteille” – lohduttava viesti suomalaisille
THL:n johtaja Mika Salmisen mukaan edessämme on paluu aivan normaaliin arkeemme, ei uuteen normaaliin. TERVEYS. 12.7.2021. https://www.iltalehti.fi/terveysuutiset/a/6e433208-821b-4dbc-b25a-6c9b1e4f0b02

OpenABM-Covid19—An agent-based model for non-pharmaceutical interventions against COVID-19 including contact tracing. PLOS. 12.7.2021. https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1009146

Coronavirus: Hong Kong study shows significant percentage of recovered patients struggle with memory loss, depression.  South China Morning Post. 12.7.2021. https://sg.news.yahoo.com/coronavirus-hong-kong-study-shows-113844553.html?guccounter=1

July 11-20

NIH study associates COVID-19 surges with mortality increases for patients (Long COVID). NIH. 8.7.2021. https://www.nih.gov/news-events/news-releases/nih-study-associates-covid-19-surges-mortality-increases-patients

Warning of serious brain disorders in people with mild coronavirus symptoms. UK neurologists publish details of mildly affected or recovering Covid-19 patients with serious or potentially fatal brain conditions. Guardian. 8.7.2020. https://www.theguardian.com/world/2020/jul/08/warning-of-serious-brain-disorders-in-people-with-mild-covid-symptoms

A Tsunami of Disability Is Coming as a Result of ‘Long COVID’
We need to plan for a future where millions of survivors are chronically ill. Scientific American. 6.7.2021. https://www.scientificamerican.com/article/a-tsunami-of-disability-is-coming-as-a-result-of-lsquo-long-covid-rsquo/

7-1-7: an organising principle, target, and accountability metric to make the world safer from pandemics. Lancet. 6.7.2021. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)01250-2/fulltext

COVID and the brain: researchers zero in on how damage occurs. Growing evidence suggests that the coronavirus causes ‘brain fog’ and other neurological symptoms through multiple mechanisms.  @IanRicksecker, If you’re interested in further understanding the host of neurological symptoms and the mechanisms underlying them, this Nature article is an excellent primer: Nature. 7.7.2021. https://www.nature.com/articles/d41586-021-01693-6

A Tsunami of Disability Is Coming as a Result of ‘Long COVID’. We need to plan for a future where millions of survivors are chronically ill. @IanRicksecker, Since our vaccines don’t stop transmission, and don’t appear to stop long-term illness, a “vaccination only” strategy is not going to be sufficient to prevent mass disability. This isn’t something we want to expose our kids to. Scientific American. 6.7.2021. https://www.scientificamerican.com/article/a-tsunami-of-disability-is-coming-as-a-result-of-lsquo-long-covid-rsquo/

Testicular pathology in fatal COVID-19: A descriptive autopsy study. @IanRicksecker, The brain isn’t the only organ affected: Testicular pathology has found evidence of “SARS-Cov-2 antigen in Leydig cells, Sertoli cells, spermatogonia, and fibroblasts” in post-morten examination. Andrology. 1.7.2021.  https://doi.org/10.1111/andr.13073

July 1-10

COVID-19 and Human Rights. Routleg. 30.6.2021. https://www.routledge.com/COVID-19-and-Human-Rights/Kjaerum-Davis-Lyons/p/book/9780367688035#

Ivermectin for the Treatment of Coronavirus Disease 2019: A Systematic Review and Meta-analysis of Randomized Controlled Trials. IDSA 28.6.2021.  https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciab591/6310839

THE STUDY OF CO2 CONCENTRATION IN A CLASSROOM DURING THE COVID-19 SAFETY MEASURES. Cold Climate HVAC & Energy 2021. 24.6.2021. https://www.e3s-conferences.org/articles/e3sconf/pdf/2021/22/e3sconf_hvac2021_01004.pdf

Long COVID in a prospective cohort of home-isolated patients. @IanRicksecker Despite a different definition of “symptoms”, the Bergen study in Norway found that 61% of patients had symptoms after six months, including 52% of patients aged 16-30 years who had not been hospitalized. Nature Medicine. 23.6.2021. https://www.nature.com/articles/s41591-021-01433-3

Dysregulation of brain and choroid plexus cell types in severe COVID-19. @IanRicksecker A joint study by Stanford and Germany’s Saarland University found inflammation in the brain, and “show[ed] that peripheral T cells infiltrate the parenchyma.” Nature. 21.6.2021. https://www.nature.com/articles/s41586-021-03710-0

Longitudinal Assessment of Diagnostic Test Performance Over the Course of Acute SARS-CoV-2 Infection. IDSA. 20.6.2021. https://academic.oup.com/jid/article/224/6/976/6311835

Why are women more prone to long Covid? While men over 50 tend to suffer the most acute symptoms of coronavirus, women who get long Covid outnumber men by as much as four to one. Guardian. 13.6.2021. https://www.theguardian.com/society/2021/jun/13/why-are-women-more-prone-to-long-covid

Breathing, speaking, coughing or sneezing: What drives transmission of SARS-CoV-2? Journal of Internal Medicine. 8.6.2021. https://doi.org/10.1111/joim.13335

Probable airborne transmission of SARS-CoV-2 in a poorly ventilated restaurant. Building and Environment. NN.6.2021. https://www.sciencedirect.com/science/article/pii/S0360132321001955?via%3Dihub

Household COVID-19 risk and in-person schooling. Science. 4.6.2021. https://www.science.org/doi/10.1126/science.abh2939

June

Mask Use and Ventilation Improvements to Reduce COVID-19 Incidence in Elementary Schools — Georgia, November 16–December 11, 2020 []sisäilman sekoittamisella päästiin 35 prosenttia pienempään koronatartuntojen esiintyvyyteen ja yhdistettynä ilmanpuhdistuksen tehostamiseen 48 prosenttia pienempään esiintyvyyteen.. CDC-MMWR. 28.5.2021. https://www.cdc.gov/mmwr/volumes/70/wr/mm7021e1.htm

Face masks effectively limit the probability of SARS-CoV-2 transmission. Science. 20.5.2021. https://doi:10.1126/science.abg6296

A paradigm shift to combat indoor respiratory infection. Science. 14.5.2021. https://doi:10.1126/science.abg2025

The 60-Year-Old Scientific Screwup That Helped Covid Kill. All pandemic long, scientists brawled over how the virus spreads. Droplets! No, aerosols! At the heart of the fight was a teensy error with huge consequences. Wired. 13.5.2021. https://www.wired.com/story/the-teeny-tiny-scientific-screwup-that-helped-covid-kill/

COVID-19 está en el aire. Numeroteca. 13.5.2021. https://numeroteca.org/cat/en-el-aire/

Embracing the science on airborne transmission is key to preventing new COVID-19 outbreaks. The Globe and Mail. 10.5.2021. https://www.theglobeandmail.com/amp/opinion/article-embracing-the-science-on-airborne-transmission-is-key-to-preventing/?utm_medium=Referrer%3A%20Social%20Network%20%2F%20Media&utm_campaign=Shared%20Web%20Article%20Links&__twitter_impression=true

May

Association between delays to patient admission from the emergency department and all- cause 30- day mortality. BMJ. 30.4.2021. https://emj.bmj.com/content/emermed/39/3/168.full.pdf

Equity vs. Ethic Literacy – Socio-Educational Dilemma in the Case of Pandemic Finland, Autumn 2020. Jyrki Loima. International Journal of Education & Literacy Studies. 30.4.2021.  http://www.journals.aiac.org.au/index.php/IJELS/article/view/6632/4602

Severe COVID-19 in people with type 1 and type 2 diabetes in Sweden: A nationwide retrospective cohort study. Lancet. 30.4.2021. https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762%2821%2900082-X/fulltext

COVID-19 Indoor Safety Guideline. https://indoor-covid-safety.herokuapp.com/

A guideline to limit indoor airborne transmission of COVID-19. PNAS. 27.4.2021. https://doi.org/10.1073/pnas.2018995118

Orthodoxy, illusio, and playing the scientific game: a Bourdieusian analysis of infection control science in the COVID-19 pandemic [version 3; peer review: 2 approved]. Wellcome Open Research. 24.5.2022. https://wellcomeopenresearch.org/articles/6-126

High-dimensional characterization of post-acute sequelae of COVID-19. Nature. 22.4.2021. https://pubmed.ncbi.nlm.nih.gov/33887749/

THE STUDY OF CO2 CONCENTRATION IN A CLASSROOM DURING THE COVID-19 SAFETY MEASURES. Cold Climate HVAC & Energy 2021. 20.4.2021. https://www.e3s-conferences.org/articles/e3sconf/pdf/2021/22/e3sconf_hvac2021_01004.pdf

Monitoring carbon dioxide to quantify the risk of indoor airborne transmission of COVID-19. MedRxiv. 16.4.2021. https://doi.org/10.1101/2021.04.04.21254903

REHVA COVID-19 guidance document. How to operate HVAC and other building service systems to prevent the spread of the coronavirus (SARS-CoV-2) disease (COVID-19) in workplaces. REHVA 15.4.2021. https://www.rehva.eu/activities/covid-19-guidance/rehva-covid-19-guidance

Ten scientific reasons in support of airborne transmission of SARS-CoV-2. Lancet. 15.4.2021. https://www.thelancet.com/article/S0140-6736(21)00869-2/fulltext

Tuore suomalaistutkimus: FFP-maski suojaa koronalta terveydenhuollossa
Väitöstutkija Lotta Oksanen suosittelee FFP-suojaimia työpisteisiin, joissa voi kohdata koronaan sairastuneen.  Lääkärilehti. 12.4.2021. https://www.laakarilehti.fi/tieteessa/uutiset/tuore-suomalaistutkimus-ffp-maski-suojaa-koronalta-terveydenhuollossa/?public=1caddc5a00d9df8176df646517b3b546

Sources of healthcare workers’ COVID‑19 infections and related safety guidelines (Lotta-Maria A.H. Oksanen). Occup Med and Environ Health 2/2021 http://ijomeh.eu/Sources-of-healthcare-workers-COVID-19-infections-and-related-safety-guidelines,132898,0,2.html

Povidone Iodine (PVP-I) Oro-Nasal Spray: An Effective Shield for COVID-19 Protection for Health Care Worker (HCW), for all. Indian J Otolaryngol Head Neck Surg. 8.4.2021. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026810/

Risk assessment for airborne disease transmission by poly-pathogen aerosols. PLOS Onre. 8.4.2021. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0248004

6-month neurological and psychiatric outcomes in 236 379 survivors of COVID-19: a retrospective cohort study using electronic health records. Lancet Psychiatry. 6.4.2021. https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(21)00084-5/fulltext

Overdispersion in COVID-19 increases the effectiveness of limiting nonrepetitive contacts for transmission control. PNAS. 6.4.2021. https://www.pnas.org/content/118/14/e2016623118

Exhaled CO2 as a COVID-19 Infection Risk Proxy for Different Indoor Environments and Activities. (Jimenez) Environmental Science & Technology. 5.4.2021. https://doi.org/10.1021/acs.estlett.1c00183

SARS-CoV-2 and Surface (Fomite) Transmission for Indoor Community Environments. CDC. 5.4.2021. https://www.cdc.gov/coronavirus/2019-ncov/more/science-and-research/surface-transmission.html

April

 

Effects of SARS-CoV-2 infection on neuroimaging and neurobehavior in neonates. World J of Pediatrics. 19.3.2021. https://link.springer.com/article/10.1007/s12519-021-00423-2

Recurrent COVID-19 including evidence of reinfection and enhanced severity in thirty Brazilian healthcare workers. J Infection. 11.3.2021. https://www.journalofinfection.com/article/S0163-4453(21)00043-8/fulltext

School reopening without robust COVID-19 mitigation risks accelerating the pandemic. Lancet. 10.3.2021. https://www.thelancet.com/journals/lancet/article/PIIS0140-67362100622-X/fulltext

Long-term clinical, virological and immunological outcomes in patients hospitalized for COVID-19: antibody response predicts long COVID. medExiv. 8.3.2021. https://www.medrxiv.org/content/10.1101/2021.03.08.21253124v1.full

A guideline to limit indoor airborne transmission of COVID-19. PNAS. 3.3.2021.  https://www.pnas.org/content/118/17/e2018995118

COVID-19 – exploring the implications of long-term condition type and extent of multimorbidity on years of life lost (YLL, UK, Italy): a modelling study. Wellcome Open Research. 1.3.2021. https://wellcomeopenresearch.org/articles/5-75

March

Adapting COVID-19 vaccines to SARS-CoV-2 variants: guidance for vaccine manufacturers Share. European Medicines Agency. 25.2.2021. https://www.ema.europa.eu/en/news/adapting-covid-19-vaccines-sars-cov-2-variants-guidance-vaccine-manufacturers

Market design to accelerate COVID-19 vaccine supply. Science. 25.2.2021. https://www.science.org/doi/10.1126/science.abg0889

Unmasking the mask studies: why the effectiveness of surgical masks in preventing
respiratory infections has been underestimated. aRxiv. 24.2.2021. https://arxiv.org/pdf/2102.04882.pdf

Outdoor Transmission of SARS-CoV-2 and Other Respiratory Viruses: A Systematic Review. J Infect Dis. 24.2.2021. https://pubmed.ncbi.nlm.nih.gov/33249484/

Karanteenin unohtava keskustelu perusoikeuksista koronanhallinnassa on nurinkurista. Thomas Bradd. 24.2.2021. https://thomasbrand.me/korona/karanteenin-unohtava-keskustelu-perusoikeuksista-koronanhallinnassa-on-nurinkurista

NIH launches new initiative to study “Long COVID”. NIH. 23.2.2021. https://www.nih.gov/about-nih/who-we-are/nih-director/statements/nih-launches-new-initiative-study-long-covid

Years of life lost to COVID-19 in 81 countries. Scientific Reports. 8.2.2021. https://www.nature.com/articles/s41598-021-83040-3

Sequelae in Adults at 6 Months After COVID-19 Infection. @IanRicksecker A University of Washington study found that 30% of Covid patients had reduced Health Related Quality of Life, with 8% of the patients limited in routine daily activities. JAMA. 19.2.2021. https://doi:10.1001/jamanetworkopen.2021.0830

Effectiveness of Mask Wearing to Control Community Spread of SARS-CoV-2. JAMA Network. 10.2.2021. https://jamanetwork.com/journals/jama/fullarticle/2776536?

Aerosol emission of adolescents voices during speaking, singing and shouting. PLOS ONE. 10.2.2021. https://doi.org/10.1371/journal.pone.0246819

Miksi Suomessa on päädytty 12 viikon rokotusväliin? Koronarokotteiden optimaalista annosväliä ei ole tutkittu, koska on pyritty mahdollisimman nopeaan ohjelmaan. Lääkärilehti. 10.2.2021. https://www.laakarilehti.fi/ajassa/ajankohtaista/miksi-suomessa-on-paadytty-12-viikon-rokotusvaliin/

Covid-19: Social murder, they wrote—elected, unaccountable, and unrepentant. BMJ. 4.2.2021. https://www.bmj.com/content/372/bmj.n314

February

SARS-CoV-2 persistence is associated with antigen-specific CD8 T-cell responses. eBioMedicine. 30.1.2021. https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(21)00023-2/fulltext

Preliminary Evidence on Long COVID in children. @IanRicksecker Children also suffer from Long Covid. ”More than half [of pediatric patients] reported at least one persisting symptom even 120 days [after] COVID-19, with 42.6% impaired by these symptoms during daily activities.” medRxiv. 26.1.2021. https://doi.org/10.1101/2021.01.23.21250375

Undercounting of Covid-19 deaths is greatest in pro-Trump areas, analysis shows. STAT. 25.1.2021. https://www.statnews.com/2021/01/25/undercounting-covid-19-deaths-greatest-in-pro-trump-areas-analysis-shows/

How COVID-19 Spreads. CDC. 14.1.2021. https://www.cdc.gov/coronavirus/2019-ncov/prevent-getting-sick/how-covid-spreads.html

Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection. Nature Immunology. 13.1.2021. https://www.nature.com/articles/s41590-021-01113-x

What is the economic impact of the latest round of lockdowns? The rich world has become better at mitigating their economic cost. Economist. 13.1.2021. https://www.economist.com/finance-and-economics/2021/01/13/what-is-the-economic-impact-of-the-latest-round-of-lockdowns

Dismantling myths on the airborne transmission of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The Journal of Hospital Infection. 12.1.2021. https://www.journalofhospitalinfection.com/article/S0195-6701(21)00007-4/fulltext

An evidence review of face masks against COVID-19. PNAS 11.1.2021. https://www.pnas.org/doi/full/10.1073/pnas.2014564118

Muistio: Koronavirusmuunnosten leviäminen Suomessa on estettävä välittömästi. Eroonkoronasta. 10.1.2021. https://www.eroonkoronasta.fi/muistio-koronavirusmuunnosten-leviaeminen-suomessa-on-estettaevae-vaelittoemaesti/

Why facemasks were not recommended despite their benefits. Pasi Malm. 2021-01-02. https://www.researchgate.net/publication/348162827_Why_facemasks_were_not_recommended_despite_their_benefits_2021-01-02

A guide towards healthy classrooms. Michael Riedeker Blog. 6.1.2021. COVID-19 | SCOEH

January 2021

Akt-Fas to Quell Aberrant T Cell Differentiation and Apoptosis in Covid-19. @IanRicksecker, There are also immunology implications:Johns Hopkins’ @fitterhappierAJ found that “CD95-mediated [T cell] differentiation and death may be advancing T cells to greater effector acquisition, fewer numbers, and immune dysregulation.” Frontiers in immunology. 21.12.2020. https://doi.org/10.3389/fimmu.2020.600405

Face masks to prevent transmission of COVID-19: A systematic review and meta-analysis. Am J Infect Control. 19.12.2020. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7748970/

Filtration Efficiency of Face Masks Used by the Public During the COVID-19 Pandemic. JAMA Network. 19.12.2020. https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2774265

The S1 protein of SARS-CoV-2 crosses the blood-brain barrier in mice. @IanRicksecker, The virus appears to be able to cross the blood-brain barrier and cause significant neurological damage. The ability of the spike protein to cross the blood-brain barrier was demonstrated in mice at the University of Washington. Nature Neuroscience. 16.12.2020. https://doi:10.1038/s41593-020-00771-8

We want them infected’: Trump appointee demanded ‘herd immunity’ strategy, emails reveal. Then-HHS science adviser Paul Alexander called for millions of Americans to be infected as means of fighting Covid-19 [GBD, Children]. Politico. 16.12.2020. https://www.politico.com/news/2020/12/16/trump-appointee-demanded-herd-immunity-strategy-446408

 

Modeling epidemic spreading through public transit using time-varying encounter network. Transp Res Part C Emerg Tecnol. 15.12.2020. https://pubmed.ncbi.nlm.nih.gov/33519128/

The Culling: Pandemic, Gerocide, Generational Affect. Medical Anthropology Quarterly. 4.12.2020. https://anthrosource.onlinelibrary.wiley.com/doi/full/10.1111/maq.12627

FINCOVID-19. Tutkimus koronataudin pitkäaikaisvaikutuksista. FILHA. 4.12.2020. https://www.filha.fi/hankkeet/fincovid-19/

Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19. Nature neuroscience. 30.11.2020. https://www.nature.com/articles/s41593-020-00758-5

No evidence for increased transmissibility from recurrent mutations in SARS-CoV-2. Nature. 25.11.2020. https://www.nature.com/articles/s41467-020-19818-2

COVID-19 pneumonia causes lower testosterone levels. Andrologia 19.11.2020. https://pubmed.ncbi.nlm.nih.gov/33210743/

Evidence of Structural Protein Damage and Membrane Lipid Remodeling in Red Blood Cells from COVID-19 Patients. @IanRicksecker, It’s also a vascular disease. A Columbia study found ”significantly altered lipid metabolism” during acute disease, which ”suggests a significant impact of SARS-CoV-2 infection on red blood cell structural membrane homeostasis.” J Proteome Res. 19.11.2020. https://doi.org/10.1021/acs.jproteome.0c00606

Immunity to the Coronavirus May Last Years, New Data Hint. Blood samples from recovered patients suggest a powerful, long-lasting immune response, researchers reported. New York Times. 17.11.2022. https://www.nytimes.com/2020/11/17/health/coronavirus-immunity.html?referringSource=articleShare

Immunological memory to SARS-CoV-2 assessed for greater than six months after infection. bioRxiv. 16.11.2020. https://www.biorxiv.org/content/10.1101/2020.11.15.383323v1

New-onset type 1 diabetes in Finnish children during the COVID-19 pandemic. Archives of Diseases in Childhood. NN.11.2020. https://adc.bmj.com/content/107/2/180

Neuropathology of patients with COVID-19 in Germany: a post-mortem case series. @IanRicksecker, Post-mortem neuropathology in Hamburg, Germany found “Infiltration by cytotoxic T lymphocytes .. in the brainstem and cerebellum, [with] meningeal cytotoxic T lymphocyte infiltration seen in 79% [of] patients.” Lancet Neurology. 11.11.2020. https://pubmed.ncbi.nlm.nih.gov/33031735/

Environmental factors involved in SARS-CoV-2 transmission: effect and role of indoor environmental quality in the strategy for COVID-19 infection control. Environmenta Health and Preventive Medicine (Japan). 3.11.2020.

Social Media Conversations in Support of Herd Immunity are Driven by Bots [GBD, Great Barrington Declaration].  Federation of American Scientists. 30.10.2020.  https://fas.org/disinfoblog/social-media-conversations-in-support-of-herd-immunity-are-driven-by-bots/

Dose-response Relation Deduced for Coronaviruses From Coronavirus Disease 2019, Severe Acute Respiratory Syndrome, and Middle East Respiratory Syndrome: Meta-analysis Results and its Application for Infection Risk Assessment of Aerosol Transmission. Clinical Infectious Diseases. 29.10.2020. https://academic.oup.com/cid/article/73/1/e241/5943160

Atlas push to ’slow the testing down’ tracks with dramatic decline in one key state [Atlas de Santis Trump Elections COVID GBD]. CNN Politics 29.10.2020.  https://edition.cnn.com/2020/10/29/politics/atlas-desantis-testing-covid-florida/index.html

Hulluksi leimaamista, vähättelyä, tukien menetyksiä: pitkä korona voi viedä työkyvyn perusterveeltä ja potilaat vaativat nyt tiedotusta. Suomessa voi olla jo tuhansia potilaita, joiden kuukausien oireilu johtuu koronasta. Toisen aallon sairastajia ei ole laskettu lukuun. YLE-Uutiset. 28.10.2020. https://yle.fi/uutiset/3-11613115

Superspreading: SARS-CoV-2 outbreak investigation in a German meat processing plant. EMBO Molecular Medicine. 27.10.2020. https://doi.org/10.15252/emmm.202013296

Fauci says Trump hasn’t attended White House coronavirus task force meeting in ’several months’. CNBC. 23.10.2020. https://www.cnbc.com/amp/2020/10/23/fauci-says-trump-hasnt-attended-white-house-coronavirus-task-force-meeting-in-several-months.html

Covid: ministers ignored Sage advice to impose lockdown or face catastrophe. Most Sage proposals not acted upon by government despite strong warnings over second wave. Guardian. 20.10.2020.  https://www.theguardian.com/world/2020/oct/12/ministers-rejected-four-out-five-proposals-from-sage-to-avert-covid-second-wave?CMP=Share_iOSApp_Other

Scientific consensus on the COVID-19 pandemic: we need to act now [John Snow Memorandum]. Lancet 15.10.2020. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32153-X/fulltext

Modelling aerosol transport and virus exposure with numerical simulations in relation to SARS-CoV-2 transmission by inhalation indoors [Ville Vuorinen, aerosol transmission]. Safety Science. nn.10.2020. https://www.sciencedirect.com/science/article/pii/S0925753520302630?via%3Dihub

THE JOHN SNOW MEMORANDUM. 14.10.2020. https://www.johnsnowmemo.com/john-snow-memo.html

Simulation of SARS-CoV-2 Aerosol Emissions in the Infected Population and Resulting Airborne Exposures in Different Indoor Scenarios. AAGR. 13.10.2020. https://aaqr.org/articles/aaqr-20-08-covid-0531

These Scientists Have A Controversial Plan For “Herd Immunity” — And The White House Is Listening. For months, a small group of scientists has pushed policies that mainstream health experts say would cause many more COVID-19 deaths. They just got their biggest audience yet [GBD Trump]. BuzzFeedNews. 9.10.2020. https://www.buzzfeednews.com/article/stephaniemlee/herd-immunity-bhattacharya-atlas-barrington

Uusi ohjelma mallintaa nopeasti, miten virusta kantavat aerosolit liikkuvat sisäilmassa. Apulaisprofessori Ville Vuorinen kehittää Suomen Akatemian rahoittamassa hankkeessa avoimen koodin ohjelmaa, joka vauhdittaa aerosolien leviämisen tutkimista. Ohjelma tekee jopa tunnissa sen, mihin aiemmin kului supertietokoneella useita päiviä. A# Uutiset. 28.9.2020. https://www.aalto.fi/fi/uutiset/uusi-ohjelma-mallintaa-nopeasti-miten-virusta-kantavat-aerosolit-liikkuvat-sisailmassa

Transmission of SARS-CoV-2 by inhalation of respiratory aerosol in the Skagit Valley Chorale superspreading event. Indoor Air. 26.9.2020. https://doi.org/10.1111/ina.12751

Superspreading: Transmission of SARS-CoV 2 During Long-Haul Flight. CDC Emerging Infectious Diseases. 18.9.2020.  https://doi:10.3201/eid2611.203299

Clustering and superspreading potential of SARS-CoV-2 infections in Hong Kong. Nature Medicine. 17.9.2020. https://www.nature.com/articles/s41591-020-1092-0

THL:n Salminen: Korona ei ole niin vaarallinen kuin pelättiin – ”Se, miltä korona näytti keväällä, ei ihan pidä paikkansa”. Koronan kokonaisvaikutus pitää arvioida uudelleen, sanoo Mika Salminen. Ilta=Sanomat. 15.9.2020. https://www.is.fi/kotimaa/art-2000006635940.html

The Impact of Vocalization Loudness on COVID-19 Transmission in Indoor Spaces. Cornell University. 9.9.2020. https://arxiv.org/abs/2009.04060

COVID-19 Is Transmitted Through Aerosols. We Have Enough Evidence, Now It Is Time to Act. TIME. 25.8.2020. https://time.com/5883081/covid-19-transmitted-aerosols/

Filtration Efficiency of Hospital Face Mask Alternatives Available for Use During the COVID-19 Pandemic. JAMA Network. 11.8.2020. https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2769443

Socio-Educational Policies and Covid-19 – A Case Study on Finland and Sweden in the Spring 2020. Jyrki Loima. International Journal of Education & Literacy Studies. 31.7.2020. http://www.journals.aiac.org.au/index.php/IJELS/article/view/6201/4383

Comparison of Face-Touching Behaviors Before and During the Coronavirus Disease 2019 Pandemic. JAMA. 29.7.2020. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2768767

Superspeading: A large COVID-19 outbreak in a high school 10 days after schools’ reopening, Israel, May 2020. Eurosurveilance. 23.7.2020. https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2020.25.29.2001352

Transmission of SARS-CoV-2 following exposure in school settings: experience from two Helsinki area exposure incidents. medRxiv. 20.7.2020. https://www.medrxiv.org/content/10.1101/2020.07.20.20156018v1

Tartuntatautirekisteriin muutoksia jotka vaikuttavat myös koronakarttasovelluksen tietoihin. [uusintainfektioiden rekisteröinti Suomessa – ei uusintainfektio jos 1 v sisällä ensimmäisestä]  THL 15.7.2020. https://thl.fi/fi/-/tartuntatautirekisteriin-muutoksia-jotka-vaikuttavat-myos-koronakarttasovelluksen-tietoihin

Selective Estrogen Receptor Modulators in COVID-19: A Possible Therapeutic Option? Frontirers in Pharmacology. 15.7.2020. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381128/

How can airborne transmission of COVID-19 indoors be minimised? Environment International. nn.7.2020. https://www.sciencedirect.com/science/article/pii/S0160412020317876

‘Only those with plastic visors were infected’: Swiss government warns against face shields. The Local 15.7.2020. https://www.thelocal.ch/20200715/only-those-with-plastic-visors-were-infected-swiss-government-warns-against-face-shields/

The emerging spectrum of COVID-19 neurology: clinical, radiological and laboratory findings. Brain. 8.7.2020. https://academic.oup.com/brain/article/143/10/3104/5868408?login=false

Warning of serious brain disorders in people with mild coronavirus symptoms. UK neurologists publish details of mildly affected or recovering Covid-19 patients with serious or potentially fatal brain conditions. Guardian. 8.7.2020. https://www.theguardian.com/world/2020/jul/08/warning-of-serious-brain-disorders-in-people-with-mild-covid-symptoms

TU Delft – Tests With Masks. YouTube. 7.7.2020. https://www.youtube.com/watch?app=desktop&v=mJ81IBTMvcU&feature=youtu.be

It Is Time to Address Airborne Transmission of Coronavirus Disease 2019 (COVID-19). Clinical Infectious Diseases. 6.7.2020.  https://academic.oup.com/cid/article/71/9/2311/5867798

Low Exhaled Breath Droplet Formation May Explain Why Children are Poor SARS-CoV-2 Transmitters. AAQR. 20.6.2020. https://aaqr.org/articles/aaqr-20-06-covid-0304

Naistenpäivän surullisenkuuluisa konsertti oli luultuakin pahempi viruslinko – jopa sata ihmistä sai koronan ja tartutti sitä vielä eteenpäin: ”Olihan se aivan erityinen tilaisuus”. MTV-Uurtiset. 11.6.2020. https://www.mtvuutiset.fi/artikkeli/naistenpaivan-surullisenkuuluisa-konsertti-oli-luultuakin-pahempi-viruslinko-jopa-sata-ihmista-sai-koronan-ja-tartutti-sita-viela-eteenpain-olihan-se-aivan-erityinen-tilaisuus/7844414

Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis. Lancet. 1.6.2020. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31142-9/fulltext

Neljä koronaan liittyvää tutkimushanketta sai Suomen Akatemian erityisrahoituksen. Hankkeet tutkivat koronavirusta, pandemiaa ja sen vaikutuksia yhteiskunnassa. Neljälle Aallon hankkeelle myönnetty kokonaissumma on 730 000 euroa. A” Uutiset. 29.5.2020. https://www.aalto.fi/fi/uutiset/nelja-koronaan-liittyvaa-tutkimushanketta-sai-suomen-akatemian-erityisrahoituksen

FFP3, FFP2, N95, surgical masks and respirators: what should we be wearing for ophthalmic surgery in the COVID-19 pandemic? Graefes Arch Clin Exp Ophthalmol. 28.5.2020. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248188/

Fallout from the COVID-19 pandemic – should we prepare for a tsunami of post viral depression? Ir J Psychol Med 15.5.2020. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431842/

Reduction of secondary transmission of SARS-CoV-2 in households by face mask use, disinfection and social distancing: a cohort study in Beijing, China. BMJ Global Health. nn.5.2020. https://pubmed.ncbi.nlm.nih.gov/32467353/

Arvostamme rakentavaa keskustelua. THL blogi. 6.5.2020. https://blogi.thl.fi/arvostamme-rakentavaa-keskustelua/

What are the underlying transmission patterns of COVID-19 outbreak? An age-specific social contact characterization. eClinicalMedicine. 1.5.2020. https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(20)30098-5/fulltext?

Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19). @IanRicksecker
This Chinese military study of the initial Wuhan outbreak concluded that “T cell counts are reduced significantly in COVID-19 patients, and the surviving T cells appear functionally exhausted.” The study authors went on to warn, “Non-ICU patients with total T cells counts lower than 800/μL may still require urgent intervention, even in the immediate absence of more severe symptoms due to a high risk for further deterioration in condition.”  Frontiers in Immunology. 1.5.2020. https://www.frontiersin.org/articles/10.3389/fimmu.2020.00827/full

What are the underlying transmission patterns of COVID-19 outbreak? An age-specific social contact characterization. eClinicalMedicine. 28.4.2020. https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(20)30098-5/fulltext?

Persistence of intestinal SARS-CoV-2 infection in patients with COVID-19 leads to re-admission after pneumonia resolved. Int J Infect Dis. 27.4.2020.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184976/

Pelkopandemia: Moderni yövartijavaltio puolustaa uhkaavilta taudeilta. Paul Lillrank. EVA analyysi. 24.4.2020. https://www.eva.fi/wp-content/uploads/2020/04/eva-analyysi-no_80.pdf

Cleaning and Disinfectant Chemical Exposures and Temporal Associations with COVID-19 – National Poison Data System, United States, January 1, 2020-March 31, 2020. CDC. 24.4.2020. https://www.cdc.gov/mmwr/volumes/69/wr/mm6916e1.htm

The effect of travel restrictions on the spread of the 2019 novel coronavirus (COVID-19) outbreak. Science. 24.4.2020. https://pubmed.ncbi.nlm.nih.gov/32144116/

Coronavirus Disease Outbreak in Call Center, South Korea. CDC Emerging Infectious Diseases. 23.4.2020. https://wwwnc.cdc.gov/eid/article/26/8/20-1274_article

Tilastokeskus julkistaa kuolleiden määrästä poikkeuksellista pikaennakkotilastoa. Tilastokeskus. 22.4.2020. https://www.stat.fi/uutinen/tilastokeskus-julkistaa-kuolleiden-maarasta-poikkeuksellista-pikaennakkotilastoa

Tutkijan synkkä laskelma: Väärä valinta koronan torjunnassa voi viedä Suomen taloudesta lähes 100 miljardia 2020-luvulla. Epidemian hidastamispolitiikka voi olla taloudelle erittäin tuhoisaa, laskee taloustieteilijä Juha Tervala. Eduskunnan tulevaisuusvaliokunta tilasi häneltä lausunnon koronaviruksen vaikutuksista. SK. 20.4.2020.  https://suomenkuvalehti.fi/jutut/kotimaa/talous/tutkijan-karu-laskelma-suomen-taloudesta-jaa-uupumaan-koronan-takia-lahes-100-miljardia-2020-luvulla-jos-nyt-valitaan-vaarin/

Etenemissuunnitelma covid-19-rajoitusten purkamiseksi. Eur-Lex. 17.4.2020. https://eur-lex.europa.eu/legal-content/FI/LSU/?uri=uriserv:OJ.C_.2020.126.01.0001.01.FIN

Dritte Ad-hoc-Stellungnahme: Coronavirus-Pandemie – Die Krise nachhaltig überwinden. Leopoldina – Nationale Academie  der Wissenschaften. 13.4.2020. https://www.leopoldina.org/uploads/tx_leopublication/2020_04_13_Coronavirus-Pandemie-Die_Krise_nachhaltig_%C3%BCberwinden_final.pdf

India has only one choice: Anders Tegnell’s (Swedish) approach. The tIMES OF iNDIA. 11.4.2020. https://timesofindia.indiatimes.com/blogs/seeing-the-invisible/india-has-only-one-choice-anders-tegnells-swedish-approach/

Football Lockdowns: Smallpox outbreak in 1972. Football makes History. 30.4.2020. https://www.footballmakeshistory.eu/smallpox-outbreak-in-1972/

Koronaviruspandemian torjunta kestävästi. Suosituksia joustavaksi riskisopeutetuksi strategiaksi [Saksan IFO:n Exit strategian suomenkielinen käännös]. 9.4.2020.  https://docs.google.com/document/d/1MT8LD4XWGj-jykgn3N2ltR4oyGZTsy5K_HVjlYpKv0c/edit#

Potential utilities of mask-wearing and instant hand hygiene for fighting SARS-CoV-2. J Med Virology. 8.4.2020. https://pubmed.ncbi.nlm.nih.gov/32232986/

Respiratory virus shedding in exhaled breath and efficacy of face masks. Nature Medicine. 3.4.2020. https://www.nature.com/articles/s41591-020-0843-2

Die Bekämpfung der CoronavirusPandemie tragfähig gestalten
Empfehlungen für eine flexible, risikoadaptierte Strategie. IFO. 2.4.2020. https://www.ifo.de/DocDL/Coronavirus-Pandemie-Strategie-Fuest-Lohse-etal-2020-04.pdf

Finnish health boss [Mika Salminen] questions WHO coronavirus testing advice. Finland’s national health authority questioned on Friday the World Health Organization’s call on countries to test as many patients as possible for coronavirus, after the country ran out of testing capacity this week. Reuters 20.3.2020. https://www.reuters.com/article/us-health-coronavirus-finland-who-idUSKBN2170ZB

Report 9: Impact of non-pharmaceutical interventions (NPIs) to reduce COVID-19 mortality and healthcare demand. Imperial College. 16.3.2020

Click to access Imperial-College-COVID19-NPI-modelling-16-03-2020.pdf

Anders Tegnell hyllar brittisk tanke kring flockimmunitet: ”Dit vi behöver komma”. LONDON. Storbritannien vill stoppa coronaviruset med hjälp av flockimmunitet. Att en majoritet av invånarna smittas och skapar ett kollektivt skydd kan även bli aktuellt i Sverige. – Vi kommer nog inte att få kontroll på det på något annat sätt, säger statsepidemiolog Anders Tegnell. Aftonbladet. 16.3.2020. https://www.aftonbladet.se/nyheter/a/6j7vaO/anders-tegnell-hyllar-brittisk-tanke-kring-flockimmunitet-dit-vi-beh

THL: Suomi on lähellä epidemiaa – koronavirustartuntoja todettu nyt 155. Metropoli. 13.3.2020. https://www.metropoli.net/uutiset/thl-suomi-on-lahella-epidemiaa-koronavirustartuntoja-todettu-nyt-155/

DEPARTMENT OF HEALTH AND HUMAN SERVICES / CENTERS FOR DISEASE CONTROL AND PREVENTION. National Center for Emerging and Zoonotic Infectious Diseases. Division of Healthcare Quality Promotion (DHQP)
Healthcare Infection Control Practices Advisory Committee March 5, 2020
Atlanta, Georgia. Record of the Proceedings. CDC. 5.3.2020. https://www.cdc.gov/hicpac/pdf/2020-March-HICPAC-Summary-508.pdf

Kuinka monen kuoleman syy on influenssa – kertovatko luvut kaiken?. Tieto&Trendit. 28.2.2020. https://www.stat.fi/tietotrendit/artikkelit/2020/kuinka-monen-kuoleman-syy-on-influenssa-kertovatko-luvut-kaiken/

Systemic Risk of Pandemic via Novel PathogensCoronavirus: A Note. New England Complex Systems Institute. 26.1.2020. https://static1.squarespace.com/static/5b68a4e4a2772c2a206180a1/t/5e2efaa2ff2cf27efbe8fc91/1580137123173/Systemic_Risk_of_Pandemic_via_Novel_Path.pdf

2020

Defining ‘T cell exhaustion’. nature reviews immunology. 30.9.2019. https://www.nature.com/articles/s41577-019-0221-9

Superspreading: Transmission of SARS-CoV 2 During Long-Haul Flight. CDC Emerging Infectious Diseases. 18.9.2020.  https://doi:10.3201/eid2611.203299

Protective and Regenerative Roles of T Cells in Central Nervous System Disorders. @IanRicksecker, For context, the parenchyma is the functional tissue of the brain – your neurons and glial cells. It isn’t normally where T cells are: “In the brain of healthy individuals, T cells are only present sporadically in the parenchyma.”Frontiers in Immunology. 12.9.2019. https://doi:10.3389/fimmu.2019.02171

Life Expectancy: Frequently Used, but Hardly Understood. [Life expectancyCohort effectsHeterogeneityHarvesting effectTempo effects] Karger. 19.8.2019. https://www.karger.com/Article/Fulltext/500955#ref22

Contamination by respiratory viruses on outer surface of medical masks used by hospital healthcare workers. BMC Infectious Diseases. 3.6.2019. https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-019-4109-x

America’s Frontline Doctors [2019, Great Barrington Declaration, Tea Party, Simone Gold].  Wikipedia. https://en.m.wikipedia.org/wiki/America%27s_Frontline_Doctors

Study Shows That Red Blood Cells Arte Stiffer in People with ME [Myalgenic Enceohalomyelitis]. ME Action. 2.1.2019.  https://www.meaction.net/2019/01/02/study-shows-that-red-blood-cells-are-stiffer-in-people-with-me/

Study of the micro-climate and bacterial distribution in the deadspace of N95 filtering face respirators. Scientific Reports. 26.11.2018. https://www.nature.com/articles/s41598-018-35693-w

Surgical masks as source of bacterial contamination during operative procedures. J Orthop Transl. 07.2018. https://www.sciencedirect.com/science/article/pii/S2214031X18300809

Syyte 21-vuotiaan kuolemantuottamuksesta: Anestesialääkäri ei käyttänyt kasvosuojainta – otimme selvää, miten leikkaussalissa yleensä toimitaan. Aamulehti. 16.5.2018. https://www.aamulehti.fi/uutiset/art-2000007303868.html

How AIDS denialism spreads in Russia through online social networks. The CONVERSATION. 3.4.2017. https://theconversation.com/how-aids-denialism-spreads-in-russia-through-online-social-networks-73875

Cleaning up the hygiene hypothesis. The rise of allergy and autoimmune diseases is due to much more than rampant cleanliness. Is it time to throw out the hygiene hypothesis? PNAS. 14.2.2017. https://www.pnas.org/doi/10.1073/pnas.1700688114

Indoor inhalation intake fractions of fine particulate matter: review of influencing factors. Indoor AIr. 12.2016. https://pubmed.ncbi.nlm.nih.gov/26562829/

Epidemiologic features of the first MERS outbreak in Korea: focus on Pyeongtaek St. Mary’s Hospital. Epidemiol Health. 17.9.2015. https://pubmed.ncbi.nlm.nih.gov/26725225/

Impact of Summer Heat on Urban Population Mortality in Europe during the 1990s: An Evaluation of Years of Life Lost Adjusted for Harvesting. PLOS One. July 2013. https://www.researchgate.net/profile/Michela-Baccini/publication/253336614_Impact_of_Summer_Heat_on_Urban_Population_Mortality_in_Europe_during_the_1990s_An_Evaluation_of_Years_of_Life_Lost_Adjusted_for_Harvesting/links/0c960539eb7aac2c74000000/Impact-of-Summer-Heat-on-Urban-Population-Mortality-in-Europe-during-the-1990s-An-Evaluation-of-Years-of-Life-Lost-Adjusted-for-Harvesting.pdf?origin=publication_detail

Bad air, amulets and mosquitoes: 2,000 years of changing perspectives on malaria. Malaria Journal. 9.7.2013. https://malariajournal.biomedcentral.com/articles/10.1186/1475-2875-12-232

A Randomized Clinical Trial of Three Options for N95 Respirators and Medical Masks in Health Workers. American Journal of Respiratory and Critical Care Medicine. 24.1.2013. https://www.atsjournals.org/doi/full/10.1164/rccm.201207-1164OC

Development of a Dose-Response Model for SARS Coronavirus. Risk Analysis. 14.10.2010. https://onlinelibrary.wiley.com/doi/10.1111/j.1539-6924.2010.01427.x

The effect of mask use on the spread of influenza during a pandemic. Risk Analysis. 20.5.2010. https://pubmed.ncbi.nlm.nih.gov/20497389/

Public Avoidance and the Epidemiology of novel H1N1 Influenza A. National Bureau of Economic Resaéarch. nn. 2.2010. https://www.nber.org/papers/w15752

Vesirokkorokotus kansalliseen rokotusohjelmaan? Duodecim. 1.2020. https://www.duodecimlehti.fi/duo98512

Pandemics: avoiding the mistakes of 1918. Nature 20.5.2009. https://www.nature.com/articles/459324a

When can dispersal synchronize populations? Theoretical Population Biology. nn.5.2008. https://www.sciencedirect.com/science/article/pii/S0040580907001396

Intake fraction distributions for indoor VOC sources in five European cities. Indoor Air 10.2007. https://pubmed.ncbi.nlm.nih.gov/17880633/

Why Most Published Research Findings Are False. OLOS Medicine. 30.8.2005. https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.0020124

Meta-analysis of the Italian studies on short-term effects of air pollution–MISA 1996-2002. [harvesting] Epidemiol Prec. Jul-Oct 2004. https://pubmed.ncbi.nlm.nih.gov/15730075/

Death and miasma in Victorian London: an obstinate belief. BMJ. 22.12.2001. https://www.bmj.com/content/323/7327/1469

How It Really Happened: What Nobody Needs to Know About Airborne Infection. Am J Respir Crit Care Med Vol 163. pp 7–8, 2001. https://www.atsjournals.org/doi/pdf/10.1164/ajrccm.163.1.hh11-00

Killer mousepox virus raises bioterror fears. New Scientist. 10.1.2001. https://www.newscientist.com/article/dn311-killer-mousepox-virus-raises-bioterror-fears/

Survival of mycobacteria on N95 personal respirators. Infect Control Hosp Epidemiol. 04.1999. doi: 10.1086/501618.

Human monkeypox in Kasaï Oriental, Zaire (1996-1997). Eurosurveillance. 11.4.1997. https://www.eurosurveillance.org/content/10.2807/esm.02.05.00161-en

CDC and the smallpox crusade. CDC. 1987. https://stacks.cdc.gov/view/cdc/21534

Epidemic cholera: its history, causes, pathology, and treatment. medicalheritagelibrary. 1849. https://archive.org/details/39002086311546.med.yale.edu

A Journal of the Plague Year by Daniel Defoe – being Observations or Memorials of the most remarkable occurrences, as well public as private, which happened in London during the last great visitation in 1665.
Written by a CITIZEN who continued all the while in London. Never made publick before. 1722.  https://www.gutenberg.org/files/376/376-h/376-h.htm

Päiväämättömät

5-11-vuotiaiden lasten rokottaminen COVID-19 tautia vastaan Suomessa. THL Nohynek. https://www.julkari.fi/handle/10024/143460

2021

 

Jatkuvasti päivittyvät

Excess mortality in England (onwards from 21.3.2022). Office for Health Improvement and Disparities. https://app.powerbi.com/view?r=eyJrIjoiYmUwNmFhMjYtNGZhYS00NDk2LWFlMTAtOTg0OGNhNmFiNGM0IiwidCI6ImVlNGUxNDk5LTRhMzUtNGIyZS1hZDQ3LTVmM2NmOWRlODY2NiIsImMiOjh9

Advice for the public: Coronavirus disease (COVID-19). WHO [frequently updated 2019…10.5.2022]. https://www.who.int/emergencies/diseases/novel-coronavirus-2019/advice-for-public

Rates of COVID-19 Cases and Deaths by Vaccination Status. CDC Covid Data Tracker. Updated monthly. CDC COVID Data Tracker: Rates of COVID-19 Cases and Deaths by Vaccination Status

Coronavirus (COVID-19) deaths worldwide per one million population as of April 26, 2022, by country https://www.statista.com/statistics/1104709/coronavirus-deaths-worldwide-per-million-inhabitants/

Demographic Trends of COVID-19 cases and deaths in the US reported to CDC. Maps, charts, and data provided by CDC, updates Tues-Sun by 8 pm ET. CDC COVID Data Tracker. https://covid.cdc.gov/covid-data-tracker/#demographics

Graphs and maps. Euromomo. https://www.euromomo.eu/graphs-and-maps

WHO Coronavirus (COVID-19) Dashboard. WHO. https://covid19.who.int/table

Lesson 1: Introduction to Epidemiology. Section 11: Epidemic Disease Occurrence. Level of disease. CDC. https://www.cdc.gov/csels/dsepd/ss1978/lesson1/section11.html

Maps in support of the Council Recommendation on a coordinated approach to travel measures in the EU. ECDC. https://www.ecdc.europa.eu/en/covid-19/situation-updates/weekly-maps-coordinated-restriction-free-movement

Tracking COVID-19 variant Omicron. https://bnonews.com/index.php/2021/11/omicron-tracker/

Suomen riski ja tartuntakartat. Suomen COVID-19 riskikartta ja tartuntatilanne kunnissa – Epidemia.fi

[New Zealand] Alert Level 4: Information on what Alert Level 4 means for you. Alert Level 4 | Unite against COVID-19 (covid19.govt.nz)

COVID Data Tracker. CDC. https://covid.cdc.gov/covid-data-tracker/#variant-proportions  https://covid.cdc.gov/covid-data-tracker/#covidnet-hospitalizations-vaccination

COVID-19 Alberta statistics. Interactive aggregate data on COVID-19 cases in Alberta. https://www.alberta.ca/stats/covid-19-alberta-statistics.htm#severe-outcomes

Coronavirus tracked: see how your country compares. Financial Times. https://ig.ft.com/coronavirus-chart/

More Than 2.3 Billion Shots Given: Covid-19 Tracker. In the U.S., 307 million doses have been administered. https://www.bloomberg.com/graphics/covid-vaccine-tracker-global-distribution/?cmpid=BBD052721_CORONAVIRUS&utm_medium=email&utm_source=newsletter&utm_term=210527&utm_campaign=coronavirus

UK summary. The official UK government website for data and insights on coronavirus (COVID-19). https://coronavirus.data.gov.uk/

Choosing Safer Activities. Vaccinated – not vaccinated. CDC. 2021. https://www.cdc.gov/coronavirus/2019-ncov/vaccines/pdfs/324153_choosingSaferActivities11.pdf

Global Report Investigating Novel Coronavirus Haplotypes. These lineages are being tracked because they have mutations of interest and evidence of international spread.Pango lineages. Global report investigating novel coronavirus haplotypes. 2021. https://cov-lineages.org/global_report.html.

KUOLEMAT JA KUOLINSYYT: MITÄ ISTAT TUOTTAA. Institut Nationale di Statistica. https://www.istat.it/it/archivio/240401

Päivittyvä koronaseuranta. Helsingin Sanomat. https://www.hs.fi/kotimaa/art-2000007780238.html

Excess mortality during the COVID-19 pandemic. https://github.com/dkobak/excess-mortality

Italia, yksityiskohtaiset Covid-19 tiedot alueittain: https://github.com/pcm-dpc/COVID-19/blob/master/dati-province/dpc-covid19-ita-province-20201231.csv

Altistumiset, tietokanta. https://altistumiset.fi/ords/f?p=102:17:504074001699701:::::

Tracking covid-19 excess deaths across countries. In many parts of the world, official death tolls undercount the total number of fatalities. The Economist. https://www.economist.com/graphic-detail/coronavirus-excess-deaths-tracker

COVID-NET A Weekly Summary of U.S. COVID-19- Associated Hospitalisations. CDC.  https://gis.cdc.gov/grasp/covidnet/COVID19_3.html

Population receiving at least one dose of a covid-19 vaccine, % of total. The Economist. https://www.economist.com/graphic-detail/tracking-coronavirus-across-the-world

Our coverage of the coronavirus. A selection of our stories about covid-19 and its consequences. The Economist. https://www.economist.com/coronavirus-pandemic

Hallituksen tiedotustilaisuudet sekä tilannekatsaukset koronavirusepidemiasta. Valtioneuvosto Statsrådet. https://valtioneuvosto.fi/tietoa-koronaviruksesta/tilannekatsaukset

General information and news. LitCov.   https://www.ncbi.nlm.nih.gov/research/coronavirus/docsum?filters=topics.General%20Info

Globaalit ja maakohtaiset koronatilastot.  https://www.worldometers.info/coronavirus/

WHO daily situation reports and corona statistics since 21.1.2020.   https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situation-reports

Maps & Trends. Follow global cases and trends. Johns Hopkins coronavirus Resource Center.   https://coronavirus.jhu.edu/data

Coronavirus Source Data. Hannah Ritchie. The data on the coronavirus pandemic is updated daily.    https://ourworldindata.org/coronavirus-source-data

covid-19-data/public/data/owid-covid-data.xlsx. Global GitHub database.   https://github.com/owid/covid-19-data/blob/master/public/data/owid-covid-data.xlsx

Korean CDC Press Releases. Public Health Weekly Reports. https://www.cdc.go.kr/board/board.es?mid=a30501000000&bid=0031&cg_code=C04

Global research on coronavirus disease (COVID-19), WHO Database.    https://www.who.int/emergencies/diseases/novel-coronavirus-2019/global-research-on-novel-coronavirus-2019-ncov

SSRN’s Coronavirus and Infectious Disease Research page provides a curated view into the early-stage research to help researchers, public health authorities, clinicians and the public understand, contain and manage this disease. https://www.ssrn.com/index.cfm/en/coronavirus/

I.Stat il tuo accesso diretto alla statistica italiana.  https://www.istat.it/it/archivio/240401

All you need to Crush covid-19.  https://www.endcoronavirus.org/

See how your community is moving around differently due to COVID-19. Community Mobility Reports.  https://www.google.com/covid19/mobility/

Tämä artikkeli käsittelee COVID-19-tautia. Sen aiheuttavaa virusta käsittelee artikkeli SARS-CoV-2 ja viruksen aiheuttamaa pandemiaa käsittelee artikkeli koronaviruspandemia 2019–2020. WIKIPEDIA. (Sisältää lukuisia täältä puuttuvia viitteitä ja linkkejä – Ajoittain päivittyvä).    https://fi.wikipedia.org/wiki/COVID-19

COVID-19  https://informationisbeautiful.net/visualizations/covid-19-coronavirus-infographic-datapack/#activities

COVID-19: Latest news updates from around the world. Twitter  https://twitter.com/i/events/1219057585707315201

Coronavirus Disease 2019 (COVID-19). Annals of Internal Medicine. (139 articles up to 9.7.2020.) https://www.acpjournals.org/topic/category/coronavirus

COVID-19 Dashboard by the Center for Systems Science and Engineering (CSSE) at Johns Hopkins University (JHU).  https://gisanddata.maps.arcgis.com/apps/opsdashboard/index.html#/bda7594740fd40299423467b48e9ecf6

Jatkuvasti päivittyvä koronagrafiikkakooste.  N.M.2020. http://pitkaranta.blogspot.com/search/label/koronavirus

Morbidity and Mortalioty Weekly Report (MMWR). CDC. N.M.  https://www.cdc.gov/mmwr/index2020.html

Download data on the weekly subnational 14-day notification rate of new COVID-19 cases. ECDC. Weekly.  https://www.ecdc.europa.eu/en/publications-data/weekly-subnational-14-day-notification-rate-covid-19

Koronavirusepidemian aikaiset rajoitukset. Valtioneuvosto.  https://valtioneuvosto.fi/tietoa-koronaviruksesta/rajoitukset-ja-suositukset

https://coronavirus-staging.data.gov.uk/

https://tradingeconomics.com/country-list/gdp-annual-growth-rate

Daily COVID-19 tests per thousand people: Because not all countries report testing data on a daily basis, daily test figures are not available for some countries in our dataset. https://ourworldindata.org/grapher/full-list-daily-covid-19-tests-per-thousand?time=2020-02-18..latest&country=BEL~DNK~FIN~FRA~GRC~ISL~ITA~NOR~SWE~CHE~GBR

The Atlantic – Covid Tracking Project: https://covidtracking.com/data/charts/us-all-key-metrics

Covid in the U.S.: Latest Map and Case Count. New York Times. https://www.nytimes.com/interactive/2020/us/coronavirus-us-cases.html

Sonderseite, Coronavirus. Frankfurter Allegemenine Zeitung. https://www.faz.net/aktuell/gesellschaft/gesundheit/coronavirus/

COVID-19: Current cases.  Information about confirmed and probable cases of COVID-19 in New Zealand. Ministry of Health. https://www.health.govt.nz/our-work/diseases-and-conditions/covid-19-novel-coronavirus/covid-19-data-and-statistics/covid-19-current-cases

COVID-19 Projections. IHME. https://covid19.healthdata.org/global?view=total-deaths&tab=trend

COVID-19 Information Hub. Astra Zeneca. https://www.astrazeneca.com/covid-19.html

RECOVERY Trial: This national clinical trial aims to identify treatments that may be beneficial for people hospitalised with suspected or confirmed COVID-19.  University of Oxford. https://www.recoverytrial.net/

Covid-19 updates. New Scientist. https://www.newscientist.com/article-topic/covid-19/#top

Template:COVID-19 pandemic data. Wikipedia. https://en.wikipedia.org/wiki/Template:COVID-19_pandemic_data

COVID-19 lockdowns. Wikipedia. https://en.wikipedia.org/wiki/COVID-19_lockdowns#Canada

Statistics and Research. Coronavirus (COVID-19) Vaccinations. Our World in Data. https://ourworldindata.org/covid-vaccinations

Osuus positiivisista COVID-19-testeistä. Vahvistettujen tapausten kokonaismäärä osuutena testattujen ihmisten kokonaismäärästä tai suoritettujen testien määrästä – sen mukaan, miten maa raportoi testitiedot. Luvut esitetään ajan mittaan viidennen vahvistetun kuoleman jälkeen kuluneiden päivien mukaan.  https://ourworldindata.org/grapher/covid19-positive-rate-since-5th-death?time=2020-02-23 .. viimeisin

GOV.UK-koronavirus (COVID-19) Isossa-Britanniassa. https://coronavirus.data.gov.uk/details/deaths

 

 

Vastaa